Напрям, який покриває ця карта
Хондроїтиназа ABC
Частина напряму: Гліальний рубець і його перебудова
Цю карту веде цей напрям як технологію
Що сюди належить
Фермент, що розщеплює гальмівні молекули рубця, введений або доставлений геном.
Що сюди не належить, хоч і схоже
Інші способи знешкодити ті самі молекули — окреме поняття модуляції протеогліканів.
Що вже дивилися
Порахували з того, як джерела каталогізують роботи, а не з їхнього читання. Це каже, скільки роботи існує і за який проміжок років — і ніколи не каже, що в ній знайшли.
- Зареєстровано або проіндексовано як робота з людьми: 61 запис · 2002–2025
- Проіндексовано як робота на тваринах: 126 записів · 2002–2026
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- Джерело не сказало, кого або що досліджували: 81 запис · 2000–2026
- Жодного клінічного випробування про це при травмі спинного мозку не зареєстровано.
Перевірено
Записи, які людина прочитала в оригіналі й опублікувала в цій карті. Вони несуть вимірювання, стан доказовості й місце на драбині.
- Chondroitinase ABC administration improves locomotor recovery after spinal cord injury.
- Enzymatic degradation of chondroitin sulfate proteoglycans with Chondroitinase ABC improves motor function after spinal cord injury.
- The locomotor benefit of chondroitinase ABC after spinal cord injury is not modified by follow-up duration or by the locomotor scoring scale used.
- The locomotor benefit of chondroitinase ABC after spinal cord injury is not modified by the injury model, the injury severity, or the number of administrations.
- A systematic review and meta-analysis of chondroitinase ABC promotes functional recovery in rat models of spinal cord injury.
- Axonal regeneration of Clarke's neurons beyond the spinal cord injury scar after treatment with chondroitinase ABC
- Chondroitinase ABC
- Chondroitinase ABC Administration in Locomotion Recovery After Spinal Cord Injury: A Systematic Review and Meta-analysis.
- Chondroitinase ABC combined with Schwann cell transplantation enhances axonal regrowth after spinal cord injury.
- Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury.
- Chondroitinase ABC combined with Schwann cell transplantation improves locomotor recovery after spinal cord injury.
- Chondroitinase ABC combined with Schwann cell transplantation improves urinary bladder function after spinal cord injury.
Знайдено у наукових джерелах, ще не перевірено
Назви й ідентифікатори так, як їх публікують джерела. Ніхто тут цих статей не читав, і ніщо на цій полиці не є результатом, рекомендацією чи доказом, що щось працює. Кожен рядок відкриває оригінал.
278 записів
Це групування — власна каталогізація джерела, а не прочитання статті. Воно каже, куди запис поклали, а не що в ньому знайшли.
мовою оригіналу · англійська
Зареєстровано або проіндексовано як робота з людьми
- Chondroitin sulphate proteoglycans in the CNS injury response. — PubMed · 2002 · Journal Article
Проіндексовано як робота на тваринах
- Impeding glial scarring hyperplasia and activating axon neogenesis via immunomodulatory microneedle patch for spinal cord repair. — PubMed · 2026 · Journal Article
- Electroacupuncture Modulation of Chondroitin Sulfate Glycosaminoglycan Promotes the Repair of Damaged Spinal Cord in Rats. — PubMed · 2026 · Journal Article
- Disrupting CSPG-Driven Microglia-Astrocyte Crosstalk Enables Scar-Free Repair in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Molecular Changes in CSPG and Glial Scar Markers in Response to Subpial Chondroitinase ABC Treatment Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Ultrasound-guided intraparenchymal injection of slow release Chondroitinase ABC-37 in the chronic phase of spinal cord injury improves long-term recovery. — PubMed · 2025 · Journal Article
- Targeting Nerve Fiber Outgrowth Inhibition After Experimental Spinal Cord Injury: A Systematic Review and Meta-analysis of Chondroitinase ABC. — PubMed · 2025 · Journal Article
- A systematic review and meta-analysis of chondroitinase ABC promotes functional recovery in rat models of spinal cord injury. — PubMed · 2024 · Journal Article
- Chronic muscle recordings reveal recovery of forelimb function in spinal injured female rats after cortical epidural stimulation combined with rehabilitation and chondroitinase ABC. — PubMed · 2022 · Journal Article
- Sustained delivery of chABC improves functional recovery after a spine injury. — PubMed · 2022 · Meta-Analysis
- A Localized Materials-Based Strategy to Non-Virally Deliver Chondroitinase ABC mRNA Improves Hindlimb Function in a Rat Spinal Cord Injury Model. — PubMed · 2022 · Journal Article
- Chondroitinase ABC/galectin-3 fusion proteins with hyaluronan-based hydrogels stabilize enzyme and provide targeted enzyme activity for neural applications. — PubMed · 2021 · Journal Article
- Delivery of chondroitinase by canine mucosal olfactory ensheathing cells alongside rehabilitation enhances recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- Self-assembling peptide hydrogels for the stabilization and sustained release of active Chondroitinase ABC in vitro and in spinal cord injuries. — PubMed · 2021 · Journal Article
- Combined treatment with enteric neural stem cells and chondroitinase ABC reduces spinal cord lesion pathology. — PubMed · 2021 · Journal Article
- PTEN-silencing combined with ChABC-overexpression in adipose-derived stem cells promotes functional recovery of spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries. — PubMed · 2020 · Journal Article
- ChABC-loaded PLGA nanoparticles: A comprehensive study on biocompatibility, functional recovery, and axonal regeneration in animal model of spinal cord injury. — PubMed · 2020 · Journal Article
- Magnetic Field Promotes Migration of Schwann Cells with Chondroitinase ABC (ChABC)-Loaded Superparamagnetic Nanoparticles Across Astrocyte Boundary in vitro. — PubMed · 2020 · Journal Article
- Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury. — PubMed · 2019 · Journal Article
- Plasticity Induced Recovery of Breathing Occurs at Chronic Stages after Cervical Contusion. — PubMed · 2019 · Journal Article
- Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains. — PubMed · 2019 · Journal Article
- Rapid and robust restoration of breathing long after spinal cord injury. — PubMed · 2018 · Journal Article
- Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury. — PubMed · 2018 · Journal Article
- Poly(glycerol sebacate) combined with chondroitinase ABC promotes spinal cord repair in rats. — PubMed · 2018 · Journal Article
- 'Chase': in dogged pursuit of a therapy for spinal cord injury. — PubMed · 2018 · Journal Article
- Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury. — PubMed · 2017 · Journal Article
- Combining Constitutively Active Rheb Expression and Chondroitinase Promotes Functional Axonal Regeneration after Cervical Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Combinatory repair strategy to promote axon regeneration and functional recovery after chronic spinal cord injury. — PubMed · 2017 · Journal Article
- Neural stem cell mediated recovery is enhanced by Chondroitinase ABC pretreatment in chronic cervical spinal cord injury. — PubMed · 2017 · Journal Article
- Local delivery of chondroitinase ABC with or without stromal cell-derived factor 1α promotes functional repair in the injured rat spinal cord. — PubMed · 2017 · Journal Article
- The combination of db-cAMP and ChABC with poly(propylene carbonate) microfibers promote axonal regenerative sprouting and functional recovery after spinal cord hemisection injury. — PubMed · 2017 · Journal Article
- Chondroitinase administration and pcDNA3.1-BDNF-BMSC transplantation promote motor functional recovery associated with NGF expression in spinal cord-transected rat. — PubMed · 2016 · Journal Article
- Combined treatment with chondroitinase ABC and treadmill rehabilitation for chronic severe spinal cord injury in adult rats. — PubMed · 2016 · Journal Article
- The incorporation of growth factor and chondroitinase ABC into an electrospun scaffold to promote axon regrowth following spinal cord injury. — PubMed · 2016 · Journal Article
- Migration of Adipose-derived Mesenchymal Stem Cells Stably Expressing Chondroitinase ABC In vitro. — PubMed · 2016 · Journal Article
- Transplantation of neural progenitor cells in chronic spinal cord injury. — PubMed · 2016 · Journal Article
- Guiding migration of transplanted glial progenitor cells in the injured spinal cord. — PubMed · 2016 · Journal Article
- Combination therapy of stem cell derived neural progenitors and drug delivery of anti-inhibitory molecules for spinal cord injury. — PubMed · 2015 · Journal Article
- Sustained delivery of chondroitinase ABC by poly(propylene carbonate)-chitosan micron fibers promotes axon regeneration and functional recovery after spinal cord hemisection. — PubMed · 2015 · Journal Article
- Local Delivery of High-Dose Chondroitinase ABC in the Sub-Acute Stage Promotes Axonal Outgrowth and Functional Recovery after Complete Spinal Cord Transection. — PubMed · 2015 · Journal Article
- Sustained dual drug delivery of anti-inhibitory molecules for treatment of spinal cord injury. — PubMed · 2015 · Journal Article
- Chondroitinase gene therapy improves upper limb function following cervical contusion injury. — PubMed · 2015 · Journal Article
- Expressing Constitutively Active Rheb in Adult Neurons after a Complete Spinal Cord Injury Enhances Axonal Regeneration beyond a Chondroitinase-Treated Glial Scar. — PubMed · 2015 · Journal Article
- [TRANSPLANTATION OF NEURAL STEM CELLS INDUCED BY ALL-TRANS- RETINOIC ACID COMBINED WITH GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR AND CHONDROITINASE ABC FOR REPAIRING SPINAL CORD INJURY OF RATS]. — PubMed · 2015 · Journal Article
- Increased migration of olfactory ensheathing cells secreting the Nogo receptor ectodomain over inhibitory substrates and lesioned spinal cord. — PubMed · 2015 · Journal Article
- Impact of treatment duration and lesion size on effectiveness of chondroitinase treatment post-SCI. — PubMed · 2015 · Journal Article
- A combination of keratan sulfate digestion and rehabilitation promotes anatomical plasticity after rat spinal cord injury. — PubMed · 2015 · Journal Article
- Plasticity of subcortical pathways promote recovery of skilled hand function in rats after corticospinal and rubrospinal tract injuries. — PubMed · 2015 · Journal Article
- Antisense vimentin cDNA combined with chondroitinase ABC promotes axon regeneration and functional recovery following spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Integrity of cortical perineuronal nets influences corticospinal tract plasticity after spinal cord injury. — PubMed · 2015 · Journal Article
- Pharmacologically inhibiting kinesin-5 activity with monastrol promotes axonal regeneration following spinal cord injury. — PubMed · 2015 · Journal Article
- Entrapment via synaptic-like connections between NG2 proteoglycan+ cells and dystrophic axons in the lesion plays a role in regeneration failure after spinal cord injury. — PubMed · 2014 · Journal Article
- Cortical PKC inhibition promotes axonal regeneration of the corticospinal tract and forelimb functional recovery after cervical dorsal spinal hemisection in adult rats. — PubMed · 2014 · Journal Article
- Examination of the combined effects of chondroitinase ABC, growth factors and locomotor training following compressive spinal cord injury on neuroanatomical plasticity and kinematics. — PubMed · 2014 · Journal Article
- Effects of an immunomodulatory therapy and chondroitinase after spinal cord hemisection injury. — PubMed · 2014 · Journal Article
- Astrocytic and vascular remodeling in the injured adult rat spinal cord after chondroitinase ABC treatment. — PubMed · 2014 · Journal Article
- Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury. — PubMed · 2014 · Journal Article
- Combination of engineered Schwann cell grafts to secrete neurotrophin and chondroitinase promotes axonal regeneration and locomotion after spinal cord injury. — PubMed · 2014 · Journal Article
- Combination of chondroitinase ABC and AAV-NT3 promotes neural plasticity at descending spinal pathways after thoracic contusion in rats. — PubMed · 2013 · Journal Article
Де це шукали і коли
Точне питання, яке поставили кожному джерелу, день, коли його поставили, і що повернулось. Нуль на цій сторінці чесний лише тоді, коли це на ній є.
| ClinicalTrials.gov | запитали, і там нічого немає | запитано 2026-09-29 | джерело знайшло 0 · програма отримала 0 · ще очікує 0 | мета: усі записи, що відповідають цьому питанню |
|---|---|---|---|---|
| Crossref | запитали, і воно відповіло | запитано 2026-09-16 | джерело знайшло 841372 · програма отримала 49 | мета: вибірка найдоречніших записів. Це джерело ранжує мішок слів, тому його власне число — це розмір корпусу, який має спільні слова, а не борг, який нам ще винні. |
| PubMed | запитали, і там нічого немає | запитано 2026-10-12 | джерело знайшло 0 · програма отримала 269 · ще очікує 0 | мета: усі записи, що відповідають цьому питанню |
Поставлене питання
- ClinicalTrials.gov
("chondroitinase ABC" OR "chondroitinase") - Crossref
spinal cord injury chondroitinase ABC chondroitinase - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Chondroitin ABC Lyase"[MeSH Terms] OR "chondroitinase ABC"[Title/Abstract] OR "chondroitinase"[Title/Abstract])