Result
Motor function · Outside our vocabulary · Efficacy
Effect as reported: [object Object]
Location in the source: abstract
we show that the combined treatment had a profound effect on functional recovery of the chronically paralyzed forelimb and paw
Study
37606910/abstract
rodent Rat · Preclinical, controlled · Not reported · 3–12 months · Not applicable
Participants actually studied: No dataNothing has been recorded here yet. This is not a zero.
No dataNothing has been recorded here yet. This is not a zero.
What this result says about which claim
- Partially supports — Enzymatic degradation of chondroitin sulfate proteoglycans with Chondroitinase ABC improves motor function after spinal cord injury.
Importantly, ChABC treatment at cervical level 4 in this chronic model also elicited improvements in gross upper arm function.
- Supports — Systemic combinatorial blockade of chondroitin sulfate proteoglycan production and the PTPσ receptor improves forelimb and paw motor function after spinal cord injury.
we show that the combined treatment had a profound effect on functional recovery of the chronically paralyzed forelimb and paw