A subject this map covers
Corticosteroids
Part of: Neuroprotection
What belongs here
High-dose steroids in the acute phase, the dispute about benefit and harm included.
What does not belong here, however close it looks
Steroids given for unrelated conditions do not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 819 records · 1950–2026
- Indexed as work in animals: 426 records · 1963–2026
- Indexed as laboratory work: 8 records · 1982–2018
- The source has not said who or what was studied: 179 records · 1959–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1432 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Magnetic Nanoparticles and Methylprednisolone Based Physico-Chemical Bifunctional Neural Stem Cells Delivery System for Spinal Cord Injury Repair. — PubMed · 2024 · Journal Article
- In Situ Piezoelectric-Catalytic Anti-Inflammation Promotes the Rehabilitation of Acute Spinal Cord Injury in Synergy. — PubMed · 2024 · Journal Article
- Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway. — PubMed · 2024 · Journal Article
- The combination treatment of methylprednisolone and growth factor-rich serum ameliorates the structural and functional changes after spinal cord injury in rat. — PubMed · 2024 · Journal Article
- Lesion level-dependent systemic muscle wasting after spinal cord injury is mediated by glucocorticoid signaling in mice. — PubMed · 2023 · Journal Article
- Schwann Cell-Derived Exosomes and Methylprednisolone Composite Patch for Spinal Cord Injury Repair. — PubMed · 2023 · Journal Article
- Formononetin ameliorates the LPS-induced inflammatory response and apoptosis of neuronal cells via NF-κB/NLRP3 signaling pathway. — PubMed · 2023 · Journal Article
- Single-Cell Sequencing Reveals the Optimal Time Window for Anti-Inflammatory Treatment in Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency. — PubMed · 2023 · Journal Article
- Microneedle/CD-MOF-mediated transdural controlled release of methylprednisolone sodium succinate after spinal cord injury. — PubMed · 2023 · Journal Article
- Carrier-Free Nanodrug Based on Co-Assembly of Methylprednisolone Dimer and Rutin for Combined Treatment of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Effects of Methylprednisolone in the Treatment of Spinal Cord Injuries by Evaluation of microRNA-21: An Experimental Study. — PubMed · 2023 · Journal Article
- Morphofunctional Changes in the Spinal Cord of Rats after Contusion Injury with Local Delivery of Methylprednisolone in Combination with a Copolymer. — PubMed · 2023 · Journal Article
- Selective Calpain Inhibition Improves Functional and Histopathological Outcomes in a Canine Spinal Cord Injury Model. — PubMed · 2022 · Journal Article
- Minocycline-Loaded Poly(α-Lipoic Acid)-Methylprednisolone Prodrug Nanoparticles for the Combined Anti-Inflammatory Treatment of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Exerting the Appropriate Application of Methylprednisolone in Acute Spinal Cord Injury Based on Time Course Transcriptomics Analysis. — PubMed · 2021 · Journal Article
- Polydopamine-Decorated Microcomposites Promote Functional Recovery of an Injured Spinal Cord by Inhibiting Neuroinflammation. — PubMed · 2021 · Journal Article
- A 3D Fiber-Hydrogel Based Non-Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Effects of Ganoderma lucidum Polysaccharides on Different Pathways Involved in the Development of Spinal Cord Ischemia Reperfusion Injury: Biochemical, Histopathologic, and Ultrastructural Analysis in a Rat Model. — PubMed · 2021 · Journal Article
- Inhibition of MAGL activates the Keap1/Nrf2 pathway to attenuate glucocorticoid-induced osteonecrosis of the femoral head. — PubMed · 2021 · Journal Article
- LncRNA CASC9 attenuates lactate dehydrogenase-mediated oxidative stress and inflammation in spinal cord injury via sponging miR-383-5p. — PubMed · 2021 · Journal Article
- Comparison of systemic and localized carrier-mediated delivery of methylprednisolone succinate for treatment of acute spinal cord injury. — PubMed · 2021 · Journal Article
- Antioxidative effects of alpha-lipoic acid in spinal cord injury An experimental rat model. — PubMed · 2021 · Journal Article
- Delayed administration of high dose human immunoglobulin G enhances recovery after traumatic cervical spinal cord injury by modulation of neuroinflammation and protection of the blood spinal cord barrier. — PubMed · 2021 · Journal Article
- Therapeutic effect of metformin on inflammation and apoptosis after spinal cord injury in rats through the Wnt/β-catenin signaling pathway. — PubMed · 2020 · Journal Article
- Alteration of glycinergic receptor expression in lumbar spinal motoneurons is involved in the mechanisms underlying spasticity after spinal cord injury. — PubMed · 2020 · Journal Article
- Effects of combined treatment of minocycline and methylprednisolone on the expression of tumor necrosis factor alpha and interleukine-6 in experimental spinal cord injury: a light and electron microscopic study. — PubMed · 2020 · Journal Article
- A novel CX3CR1 inhibitor AZD8797 facilitates early recovery of rat acute spinal cord injury by inhibiting inflammation and apoptosis. — PubMed · 2020 · Journal Article
- Why do anti-inflammatory signals of bone marrow-derived stromal cells improve neurodegenerative conditions where anti-inflammatory drugs fail? — PubMed · 2020 · Journal Article
- EDNRB Reverses Methylprednisolone-Mediated Decrease in Neural Progenitor Cell Viability via Regulating PI3K/Akt Pathway and lncRNA Expression. — PubMed · 2020 · Journal Article
- Research on the Effects of Levetiracetam in Spinal Cord Injury Model in Rats: An Experimental Study. — PubMed · 2020 · Journal Article
- Alkaline-phosphatase triggered self-assemblies enhances the anti-inflammatory property of methylprednisolone in spinal cord injury. — PubMed · 2020 · Journal Article
- Risk factors associated with progressive myelomalacia in dogs with complete sensorimotor loss following intervertebral disc extrusion: a retrospective case-control study. — PubMed · 2019 · Journal Article
- Protective effects of dantrolene and methylprednisolone against spinal cord injury-induced early oxidative damage in rabbit bladder: A comparative experimental study. — PubMed · 2019 · Journal Article
- Relationships between microRNA-20a and microRNA-125b expression and apoptosis and inflammation in experimental spinal cord injury. — PubMed · 2019 · Journal Article
- Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury. — PubMed · 2019 · Journal Article
- Resveratrol treatment of spinal cord injury in rat model. — PubMed · 2019 · Journal Article
- Can Quercetin be an Option for Treatment of Spinal Cord Injury? An Experimental Study. — PubMed · 2019 · Journal Article
- Evaluation of the neuroprotective effects of anti-inflammatory drugs in experimental spinal cord damage. — PubMed · 2019 · Journal Article
- Spinal Cord Injury in Rats Disrupts the Circadian System. — PubMed · 2018 · Journal Article
- Methylprednisolone treatment enhances early recovery following surgical decompression for degenerative cervical myelopathy without compromise to the systemic immune system. — PubMed · 2018 · Journal Article
- Effect evaluation of methylprednisolone plus mitochondrial division inhibitor-1 on spinal cord injury rats. — PubMed · 2018 · Journal Article
- FNDC5 expression in Purkinje neurons of adult male rats with acute spinal cord injury following treatment with methylprednisolone. — PubMed · 2018 · Journal Article
- Methylprednisolone inhibits the proliferation of endogenous neural stem cells in nonhuman primates with spinal cord injury. — PubMed · 2018 · Journal Article
- Changes of Spinal Edema and Expression of Aquaporin 4 in Methylprednisolone-treated Rats with Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Anti-inflammatory effect of Mongolian drug Naru-3 on traumatic spinal cord injury and its mechanism of action. — PubMed · 2018 · Evaluation Study
- Epidermal growth factor regulates apoptosis and oxidative stress in a rat model of spinal cord injury. — PubMed · 2018 · Journal Article
- Therapeutic Effect of Curcumin and Methylprednisolone in the Rat Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Neuroprotective Effects of C-terminal Domain of Tetanus Toxin on Rat Brain Against Motorneuron Damages After Experimental Spinal Cord Injury. — PubMed · 2018 · Journal Article
- [Effect of Buyanghuanwu decoction on the expression of platelet activating factor after acute spinal cord injury in rats]. — PubMed · 2018 · Journal Article
- Granulocyte Colony-Stimulating Factor Combined with Methylprednisolone Improves Functional Outcomes in Rats with Experimental Acute Spinal Cord Injury. — PubMed · 2018 · Evaluation Study
- Albumin-Conjugated Lipid-Based Multilayered Nanoemulsion Improves Drug Specificity and Anti-Inflammatory Potential at the Spinal Cord Injury gSite after Intravenous Administration. — PubMed · 2018 · Journal Article
- Effects of aquaporin 4 and inward rectifier potassium channel 4.1 on medullospinal edema after methylprednisolone treatment to suppress acute spinal cord injury in rats. — PubMed · 2018 · Journal Article
- [Effects of decompression combined with electro-acupuncture on rat with acute severe upper cervical spinal cord compression injury]. — PubMed · 2018 · Journal Article
- Effects of Intrathecal Caffeic Acid Phenethyl Ester (CAPE) on IL-6 and TNF-α Levels and Local Inflammatory Responses in Spinal Cord Injuries. — PubMed · 2018 · Comparative Study
- Evaluation of the effect of BMSCs condition media and methylprednisolone in TGF-β expression and functional recovery after an acute spinal cord injury. — PubMed · 2018 · Journal Article
- Methods for Assessing Serpins as Neuroprotective Therapeutics. — PubMed · 2018 · Journal Article
- The role of low level laser therapy on neuropathic pain relief and interleukin-6 expression following spinal cord injury: An experimental study. — PubMed · 2018 · Journal Article
- Localized delivery of methylprednisolone sodium succinate with polymeric nanoparticles in experimental injured spinal cord model. — PubMed · 2017 · Journal Article
- Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles. — PubMed · 2017 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 8 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 838759 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 3 · this programme has 1421 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("methylprednisolone" OR "corticosteroid") - Crossref
spinal cord injury methylprednisolone corticosteroid - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Methylprednisolone"[MeSH Terms] OR "Adrenal Cortex Hormones"[MeSH Terms] OR "methylprednisolone"[Title/Abstract] OR "corticosteroid"[Title/Abstract])