A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Gasotransmitters in the regulation of connexins in central and peripheral nervous system injuries. — PubMed · 2027 · Journal Article
- Lipid droplets as redox-active organelles after spinal cord injury: lipid peroxidation, mitochondrial dysfunction, and neuroinflammation. — PubMed · 2026 · Journal Article
- Cuproptosis in spinal cord injury: emerging mechanisms and immunological relevance. — PubMed · 2026 · Journal Article
- Cooperative protein-ligand antioxidant activation: Sulforaphane binding to human serum immunoglobulin Genhances neuroprotection in spinal cord neurons via structural and functional modifications. — PubMed · 2026 · Journal Article
- Mesenchymal stem cell-derived small extracellular vesicles in spinal cord injury: From molecular repair mechanisms to standardized translational development. — PubMed · 2026 · Journal Article
- Recent advances in fucoidan for stem cell protection and regenerative tissue repair. — PubMed · 2026 · Journal Article
- Comparison of deep and nondeep hypothermia in thoracic and thoracoabdominal aortic surgery: A systematic review and meta-analysis. — PubMed · 2026 · Journal Article
- Future Directions Related to Spinal Cord Compression: Where Will we be in the Next 10 Years? — PubMed · 2026 · Journal Article
- Introduction to Evolving Concepts Related to Spinal Cord Compression. — PubMed · 2026 · Journal Article
- Neuroprotection of the Compressed Spine: A Systematized Narrative Review of Riluzole for Humans with Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Optimizing Spinal Cord Perfusion in Traumatic and Non-traumatic Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Pathophysiology and Repair Potential in Degenerative Cervical Myelopathy. — PubMed · 2026 · Journal Article
- The role of PANoptosis regulatory networks in acute neurological injury. — PubMed · 2026 · Journal Article
- Metallotoxicity-driven oxidative perturbations in spinal cord injury: Unraveling the pathophysiological nexus between metal-induced redox imbalance and disease severity: A correlational and multivariate analysis. — PubMed · 2026 · Journal Article
- Metabolic Collapse in Acute CNS Injury: A Spatiotemporal Framework Linking Redox Failure, Ferroptosis, and Neurovascular Dysfunction. — PubMed · 2026 · Journal Article
- Mitochondrial homeostasis imbalance-triggered PANoptosis in traumatic brain and spinal cord injury: from mechanism to therapeutic strategies. — PubMed · 2026 · Journal Article
- PPARGC1A Modulation Attenuates Ferroptosis-Related Injury and Promotes Functional Recovery After Spinal Cord Injury: Potential Involvement of PPARγ Signaling. — PubMed · 2026 · Journal Article
- The multifaceted role of B cells in traumatic spinal cord injury: Antibody-dependent and antibody-independent mechanisms. — PubMed · 2026 · Journal Article
- MicroRNA-Ferroptosis-Spinal Cord Injury: A Complex Interplay in Neurodegeneration and Repair. — PubMed · 2026 · Journal Article
- Trichostatin A-primed spinal cord organoids alleviate oxidative stress and improve recovery after spinal cord injury involving the NRF2/HO-1 signaling pathway. — PubMed · 2026 · Journal Article
- Alkaloids as Emerging Neuroprotective Agents for Neurodegenerative Disorders: Insights into Tryptanthrin and Its Derivatives. — PubMed · 2026 · Journal Article
- Andrograpanin attenuates secondary neuroinflammation after spinal cord injury by modulating microglial glycolysis via HIF-1α. — PubMed · 2026 · Journal Article
- Lipid Metabolism in Central Nervous System Diseases: Pathological Mechanisms and Therapeutic Advances. — PubMed · 2026 · Journal Article
- Lost in translation: why pharmacological trials keep failing in acute spinal cord injury. — PubMed · 2026 · Journal Article
- Notch Signaling in Spinal Cord Injury: Mechanistic Insights and Therapeutic Perspectives. — PubMed · 2026 · Journal Article
- Targeting Neurodegeneration With Naringenin: Mechanistic Perspectives and Therapeutic Implications. — PubMed · 2026 · Journal Article
- The Pleiotropic Therapeutic Perspectives of GLP-1 and GIP Receptor Agonists in Spinal Cord Injury: A Narrative Review. — PubMed · 2026 · Journal Article
- Research Progress on Regulating Neuroinflammation After Spinal Cord Injury by Targeting the cGAS-STING Pathway. — PubMed · 2026 · Journal Article
- Multifunctional nanozyme platforms in central nervous system therapies: from rational design to translational medicine. — PubMed · 2026 · Journal Article
- Clinical trial landscape of cell therapy for spinal cord injury: from integrated practices to future developments. — PubMed · 2026 · Journal Article
- Mechanism and therapeutic potential of mitophagy in spinal cord injury. — PubMed · 2026 · Journal Article
- Dynamic activation of lytic cell death-related programs identifies CD14 as a candidate hub gene associated with secondary injury after spinal cord injury. — PubMed · 2026 · Journal Article
- Advances in tailored intraparenchymal delivery of regenerative medicine for spinal cord injury: a review of preclinical studies and clinical trials. — PubMed · 2026 · Journal Article
- Elezanumab for the treatment of spinal cord injury: assessing the clinical development journey to date. — PubMed · 2026 · Journal Article
- Harnessing wireless electrical stimulation and silk-based conductive hydrogels to boost iPSC-derived astrocytes neuroprotection and guide macrophage polarisation in vitro for spinal cord repair. — PubMed · 2026 · Journal Article
- Neural Stem Cell-Derived Extracellular Vesicles: The Next Frontier in Neurological and Neurodegenerative Diseases. — PubMed · 2026 · Journal Article
- Platelet lysate derived macroporous hydrogel loaded with adipose stem cells for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Remarkable Recovery After Delayed High-Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury. — PubMed · 2026 · Case Reports
- STAT3 Signaling in Spinal Cord Injury: Neurochemical Mechanisms Linking Neuroinflammation, Mitochondrial Stress, and Glial Remodeling. — PubMed · 2026 · Journal Article
- GLP-1 Receptor Agonists in Neurological Disorders: From Mechanisms to Clinical Translation. — PubMed · 2026 · Journal Article
- Restoring neuroplasticity after CNS trauma: cell therapy approaches in spinal cord and traumatic brain injury. — PubMed · 2026 · Journal Article
- Translational potential of GMP-grade human umbilical cord-derived mesenchymal stem cells (UC-MSCs) in traumatic spinal cord injury: a preclinical study in rat. — PubMed · 2026 · Journal Article
- The neuroprotective and therapeutic potential of resveratrol for traumatic spinal cord injuries: a systematic review. — PubMed · 2026 · Journal Article
- Sexual Dimorphism in Spinal Cord Injury: From Molecular Mechanisms to Clinical Translation. — PubMed · 2026 · Journal Article
- Microglia-vascular interactions after spinal cord injury: regulatory mechanisms and therapeutic advances. — PubMed · 2026 · Journal Article
- Mechanisms and therapeutic potential of hydrogen sulfide in traumatic central nervous system injuries. — PubMed · 2026 · Journal Article
- Riluzole in neuroinflammation and neurodegeneration: Mechanistic insights and experimental validation. — PubMed · 2026 · Journal Article
- The Role of Interleukin-18 After Spinal Cord Injury: Mechanisms and Therapeutic Potential. — PubMed · 2026 · Journal Article
- The immune dysregulation landscape and dynamic regulation of competing endogenous RNAs in spinal cord injury. — PubMed · 2026 · Journal Article
- Multimodal Toxicity of Acrolein and Associated Therapeutic Strategies in Central Nervous System Trauma and Disease. — PubMed · 2026 · Journal Article
- Targeted H(2)S Delivery System Attenuates Blood-Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway. — PubMed · 2026 · Journal Article
- The role of sex hormones in neurological and functional recovery following spinal cord injury in females: a systematic review of the literature. — PubMed · 2026 · Journal Article
- Phase-dependent efficacy of intravenous amniotic mesenchymal stem cells in a rat spinal cord injury model. — PubMed · 2026 · Journal Article
- The evolving landscape of spinal cord injury: a tale of 3 decades. — PubMed · 2026 · Journal Article
- Enhanced MIF/CD74 axis activity shapes B cell functioning following traumatic spinal cord injury. — PubMed · 2026 · Journal Article
- Neurosurgery as an immune anchor point: a translational framework for perioperative immunoengineering. — PubMed · 2026 · Journal Article
- Spatiotemporal Delivery of a Cell-Free DNA Scavenger for Detoxification and Neural Repair after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Network Pharmacology Combined With Clinical Retrospective Analysis to Investigate the Potential Mechanisms and Clinical Significance of Folate in Treating Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Reprogramming the Inflammatory Response to Promote Neural Stem Cell Function After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- From medicinal herb to neuroprotective candidate: A review of curculigoside's potential in central nervous system disorders. — PubMed · 2026 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 6 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1230843 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 3744 · this programme has 3744 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])