A subject this map covers
Corticosteroids
Part of: Neuroprotection
What belongs here
High-dose steroids in the acute phase, the dispute about benefit and harm included.
What does not belong here, however close it looks
Steroids given for unrelated conditions do not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 819 records · 1950–2026
- Indexed as work in animals: 426 records · 1963–2026
- Indexed as laboratory work: 8 records · 1982–2018
- The source has not said who or what was studied: 179 records · 1959–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1432 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Effects of low-dose methotrexate in spinal cord injury in rats. — PubMed · 2013 · Journal Article
- The dose-dependent neuroprotective effect of alpha-lipoic acid in experimental spinal cord injury. — PubMed · 2013 · Comparative Study
- Effects of combining methylprednisolone with rolipram on functional recovery in adult rats following spinal cord injury. — PubMed · 2013 · Journal Article
- [Effects of intrathecal injection of methylprednisolone sodium succinate in acute spinal cord injury rabbits]. — PubMed · 2013 · English Abstract
- Neuroprotective effect of cocaine- and amphetamine-regulated transcript peptide in spinal cord injury in mice. — PubMed · 2013 · Journal Article
- The effect of methylprednisolone intravenous infusion on the expression of ciliary neurotrophic factor in a rat spinal cord injury model. — PubMed · 2013 · Journal Article
- Microglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injury. — PubMed · 2013 · Journal Article
- Mn (III) tetrakis (4-benzoic acid) porphyrin scavenges reactive species, reduces oxidative stress, and improves functional recovery after experimental spinal cord injury in rats: comparison with methylprednisolone. — PubMed · 2013 · Comparative Study
- Protective effect of ginkgolide B against acute spinal cord injury in rats and its correlation with the Jak/STAT signaling pathway. — PubMed · 2013 · Comparative Study
- A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte-secreted vimentin. — PubMed · 2013 · Journal Article
- The comparison of neuroprotective effects of intrathecal dexmedetomidine and metilprednisolone in spinal cord injury. — PubMed · 2013 · Journal Article
- Neuroprotective effects of hypothermia after spinal cord injury in rats: comparative study between epidural hypothermia and systemic hypothermia. — PubMed · 2012 · Comparative Study
- Analysis of methylprednisolone-induced inhibition on the proliferation of neural progenitor cells in vitro by gene expression profiling. — PubMed · 2012 · Journal Article
- Neuroprotective effects of racemic ketamine and (S)-ketamine on spinal cord injury in rat. — PubMed · 2012 · Comparative Study
- Methothrexate attenuates early neutrophil infiltration and the associated lipid peroxidation in the injured spinal cord but does not induce neurotoxicity in the uninjured spinal cord in rats. — PubMed · 2012 · Journal Article
- Response to 'The administration of high-dose methylprednisolone for 24 h reduced muscle size and increased atrophy-related gene expression in spinal cord-injured rats'. — PubMed · 2012 · Letter
- Stability, disposition, and penetration of catalytic antioxidants Mn-porphyrin and Mn-salen and of methylprednisolone in spinal cord injury. — PubMed · 2012 · Journal Article
- BDNF and NT-3 expression by using glucocorticoid-induced bicistronic expression vector pGC-BDNF-IRES-NT3 protects apoptotic cells in a cellular injury model. — PubMed · 2012 · Journal Article
- Mechanisms of injury and emergency care of acute spinal cord injury in dogs and cats. — PubMed · 2012 · Journal Article
- Autophagy is activated in injured neurons and inhibited by methylprednisolone after experimental spinal cord injury. — PubMed · 2012 · Journal Article
- [Effect of methylprednisolone on neurological behavior and the BDNF and NMDA receptor expression after traumatic spinal cord injury in rats]. — PubMed · 2012 · English Abstract
- A reassessment of a classic neuroprotective combination therapy for spinal cord injured rats: LPS/pregnenolone/indomethacin. — PubMed · 2012 · Comparative Study
- A reassessment of LPS/indomethacin/pregnenolone combination therapy after spinal cord injury in rats. — PubMed · 2012 · Journal Article
- Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats. — PubMed · 2012 · Journal Article
- Testosterone reduced methylprednisolone-induced muscle atrophy in spinal cord-injured rats. — PubMed · 2012 · Journal Article
- Low dose estrogen prevents neuronal degeneration and microglial reactivity in an acute model of spinal cord injury: effect of dosing, route of administration, and therapy delay. — PubMed · 2011 · Journal Article
- The administration of high-dose methylprednisolone for 24 h reduced muscle size and increased atrophy-related gene expression in spinal cord-injured rats. — PubMed · 2011 · Journal Article
- Treatment of experimental spinal cord injury with 3β-methoxy-pregnenolone. — PubMed · 2011 · Journal Article
- Do corticosteroids affect lumbar spinal fusion? A rabbit model using high-dose methylprednisolone. — PubMed · 2011 · Journal Article
- The effect of irradiation and methylprednisolone in spinal cord injured rats. — PubMed · 2011 · Journal Article
- [Impacts of high-dose methylprednisolone on gene expression profiling in acute spinal cord injury]. — PubMed · 2011 · English Abstract
- Pregabalin as a neuroprotector after spinal cord injury in rats: biochemical analysis and effect on glial cells. — PubMed · 2011 · Journal Article
- Antioxidant effects of curcumin in spinal cord injury in rats. — PubMed · 2011 · Comparative Study
- Comparative neuroprotective effects of methylprednisolone and rosiglitazone, a peroxisome proliferator-activated receptor-γ following spinal cord injury. — PubMed · 2011 · Comparative Study
- Effects of a single dose of methylprednisolone versus three doses of rosiglitazone on nerve growth factor levels after spinal cord injury. — PubMed · 2011 · Journal Article
- Protective effects of edaravone on experimental spinal cord injury in rats. — PubMed · 2011 · Comparative Study
- Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury. — PubMed · 2010 · Journal Article
- Combined hyperbaric oxygen and hypothermia treatment on oxidative stress parameters after spinal cord injury: an experimental study. — PubMed · 2010 · Journal Article
- Evaluation of protective effects of the alpha lipoic acid after spinal cord injury: an animal study. — PubMed · 2010 · Journal Article
- Tetraparesis resembling acute transverse myelitis in a captive chimpanzee (Pan troglodytes): long-term care and recovery. — PubMed · 2010 · Case Reports
- Curcumin improves early functional results after experimental spinal cord injury. — PubMed · 2010 · Comparative Study
- Glucocorticoid protection of oligodendrocytes against excitotoxin involving hypoxia-inducible factor-1alpha in a cell-type-specific manner. — PubMed · 2010 · Journal Article
- Neuroprotective effects of gabapentin in experimental spinal cord injury. — PubMed · 2010 · Comparative Study
- Neuroprotective efficacy of estrogen in experimental spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Postinjury estrogen treatment of chronic spinal cord injury improves locomotor function in rats. — PubMed · 2010 · Journal Article
- What is your diagnosis? Occipitoatlantoaxial malformation and spinal cord compression secondary to intervertebral disk degeneration and herniation. — PubMed · 2010 · Case Reports
- Neuroprotective effect of mesna (2-mercaptoethane sulfonate) against spinal cord ischemia/reperfusion injury in rabbits. — PubMed · 2010 · Journal Article
- The effectiveness of dexmedetomidine in experimental spinal cord injury compared to methylprednisolone in rats. — PubMed · 2010 · Journal Article
- Ultrastructural changes in the liver after experimental spinal cord injury in rats: effects of methylprednisolone, immunoglobulin g and albumin. — PubMed · 2010 · Journal Article
- Protective effects of tadalafil on experimental spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Reducing macrophages to improve bone marrow stromal cell survival in the contused spinal cord. — PubMed · 2010 · Journal Article
- Early metabolic reactivation versus antioxidant therapy after a traumatic spinal cord injury in adult rats. — PubMed · 2010 · Comparative Study
- Comparison of the effect of mexiletine and methylprednisolone on neural function and histopathological damage after transient spinal cord ischemia in rabbits. — PubMed · 2010 · Journal Article
- The biochemical effectiveness of N-acetylcysteine in experimental spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Antiapoptotic and neuroprotective effects of mycophenolate mofetil after acute spinal cord injury in young rats. — PubMed · 2009 · Journal Article
- Methylprednisolone fails to improve functional and histological outcome following spinal cord injury in rats. — PubMed · 2009 · Journal Article
- Olfactory bulb implantation and methylprednisolone administration in the treatment of spinal cord injury in rats. — PubMed · 2009 · Journal Article
- Effects of dexmedetomidine or methylprednisolone on inflammatory responses in spinal cord injury. — PubMed · 2009 · Comparative Study
- [Effects of high dose methylprednisolone on cell apoptosis and Bcl-2 expression after acute spinal cord injuries in rats]. — PubMed · 2009 · English Abstract
- Magnesium chloride in a polyethylene glycol formulation as a neuroprotective therapy for acute spinal cord injury: preclinical refinement and optimization. — PubMed · 2009 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 8 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 838759 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 3 · this programme has 1421 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("methylprednisolone" OR "corticosteroid") - Crossref
spinal cord injury methylprednisolone corticosteroid - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Methylprednisolone"[MeSH Terms] OR "Adrenal Cortex Hormones"[MeSH Terms] OR "methylprednisolone"[Title/Abstract] OR "corticosteroid"[Title/Abstract])