A subject this map covers
Extracellular vesicles and exosomes
Part of: Cell therapy
What belongs here
Products of cells without the cells: vesicles, exosomes, conditioned medium, delivered in spinal cord injury.
What does not belong here, however close it looks
Delivering living cells, even when the authors credit their vesicles, is cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 226 records · 2000–2026
- Indexed as work in animals: 224 records · 1998–2026
- Indexed as laboratory work: 33 records · 2003–2026
- The source has not said who or what was studied: 171 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
654 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- LPS Pre-Conditioned Olfactory Ensheathing Cells Derived Extracellular Vesicle Regulate Microglia Polarization Through mir-1224/CD44/SLC7A11 Axis Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Olfactory Mucosa Mesenchymal Stem Cell-Derived Exosomal lncRNA RMRP Regulates Glial Metabolic Reprogramming to Promote Axonal Regeneration After Spinal Cord Injury by Inhibiting WTAP-Mediated p53 m(6)A. — PubMed · 2026 · Journal Article
- Dual-engineered Treg-Exosome-IKVAV nanovesicles spatiotemporally sequentially regulate neuro-immune microenvironment to promote spinal cord injury repair. — PubMed · 2026 · Journal Article
- Hypoxia-conditioned BMSC exosomes improve short-term spinal cord injury outcomes via the miR-615-3p/PDE4C-mediated cAMP/PKA pathway. — PubMed · 2026 · Journal Article
- Comparison of the Safety and Efficacy of Hypoxia-Conditioned Mesenchymal Stem Cells and Their Extracellular Vesicles in a Spinal Cord Injury Rat Model. — PubMed · 2026 · Journal Article
- Collagen-Based Hydrogel Loaded With Microspheres Encapsulated With Placental Mesenchymal Stem Cells-Derived Exosomes Synergistically Promote Recovery After Spinal Cord Injury in Rats. — PubMed · 2026 · Journal Article
- MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Olfactory ensheathing cell transplantation targets macrophage extracellular traps and NKCC1 to alleviate pain after spinal cord injury. — PubMed · 2026 · Journal Article
- Niche-targeted paracrine signaling from OMSCs restores the regenerative microenvironment after SCI. — PubMed · 2025 · Journal Article
- Photobiomodulation Reduces Fibrous Scar Formation After Spinal Cord Injury by Downregulating CXCL3 Expression in Macrophages. — PubMed · 2025 · Journal Article
- MiR499-5P loaded MSC derived exosomes affect oxidative stress and inflammatory response after spinal cord injury by targeting genes. — PubMed · 2025 · Journal Article
- Engineered BMSC-derived exosomes deliver miR-17-5p inhibitor to restore sensory conduction via the IL-11/GP130/STAT3/GAP-43 axis in dorsal column lesion. — PubMed · 2025 · Journal Article
- Exosomal miR-494 from Bone Marrow Mesenchymal Stem Cells Attenuates Ferroptosis and Enhances Spinal Cord Injury Repair by Modulating the SIRT1/HO-1 Pathway. — PubMed · 2025 · Journal Article
- The Combination of Sodium Tanshinone IIA Sulfonate and Mesenchymal Stem Cell-derived Exosomes Against Spinal Cord Injury via VEGF Pathway. — PubMed · 2025 · Journal Article
- BMSCs-derived exosomal AKAP12 alleviates neuronal cell ferroptosis by inhibiting the STAT3 and ERK signaling pathways in spinal cord injury. — PubMed · 2025 · Journal Article
- miR-218a-5p derived from neural stem cell-exosomes inhibits ferroptosis in spinal cord injury through the Bmil/Mettl3/Alox12 axis. — PubMed · 2025 · Journal Article
- Nasal Delivery of Engineered Exosomes via a Thermo-Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair. — PubMed · 2025 · Journal Article
- The role of astrocyte-derived extracellular vesicles in cellular microenvironment remodeling after spinal cord injury: A study based on quantitative proteomics analysis. — PubMed · 2025 · Journal Article
- Three-Dimensional-Printed Gelatin Methacryloyl Scaffold Loaded with Extracellular Vesicles Derived from H(2)S Preconditioned Mesenchymal Stromal Cells Promotes Neuronal Regeneration in Rats with Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Exosomal miR-17-92 Cluster from BMSCs Alleviates Apoptosis and Inflammation in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Bone marrow mesenchymal stem cells-derived exosomal miR-24-3p alleviates spinal cord injury by targeting MAPK9 to inhibit the JNK/c-Jun/c-Fos pathway. — PubMed · 2025 · Journal Article
- Engineered Exosome-Loaded Silk Fibroin Composite Hydrogels Promote Tissue Repair in Spinal Cord Injury Via Immune Checkpoint Blockade. — PubMed · 2025 · Journal Article
- Exosomal lncRNA RMRP-shuttled by Olfactory Mucosa-Mesenchymal Stem Cells Suppresses Microglial Pyroptosis to Improve Spinal Cord Injury via EIF4A3/SIRT1. — PubMed · 2025 · Journal Article
- MiR-124 Delivered by Extracellular Vesicles from Mesenchymal Stem Cell Exerts Neuroprotective Effects by Stabilizing the p62-Keap1-Nrf2 Pathway after Spinal Cord Injury in Rats. — PubMed · 2025 · Journal Article
- A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis. — PubMed · 2025 · Journal Article
- Engineered small extracellular vesicles for targeted delivery of perlecan to stabilise the blood-spinal cord barrier after spinal cord injury. — PubMed · 2025 · Journal Article
- Systemic stem cell treatment rescues injured motoneurons by reducing L-selectin expression on leukocytes. — PubMed · 2025 · Journal Article
- Evaluating purified exosome product and its role in neurologic and functional recovery following spinal cord injury in female rats. — PubMed · 2025 · Journal Article
- An engineering-reinforced extracellular vesicle-integrated hydrogel with an ROS-responsive release pattern mitigates spinal cord injury. — PubMed · 2025 · Journal Article
- LncRNA 4933431K23Rik modulate microglial phenotype via inhibiting miR-10a-5p in spinal cord injury induced neuropathic pain. — PubMed · 2025 · Journal Article
- An injectable responsive exosome-releasing hydrogel based on sodium alginate restores motor and bladder function by alleviating the injury microenvironment and facilitating distal nerve repair. — PubMed · 2025 · Journal Article
- Intranasal Delivery of Brain-Derived Neurotrophic Factor (BDNF)-Loaded Small Extracellular Vesicles for Treating Acute Spinal Cord Injury in Rats and Monkeys. — PubMed · 2025 · Journal Article
- 2-Mercaptoethanol enhances the yield of exosomes showing therapeutic potency in alleviating spinal cord injury mice. — PubMed · 2025 · Journal Article
- Decellularized tissue matrices hydrogels functionalized with extracellular vesicles promote macrophage reprogramming and neural stem cell differentiation for spinal cord injury repair. — PubMed · 2025 · Journal Article
- Resveratrol loaded microglia-derived exosomes attenuate astrogliasis by restoring mitochondrial function to reduce spinal cord injury. — PubMed · 2025 · Journal Article
- Engineered Extracellular Vesicles Modified by Angiopep-2 Peptide Promote Targeted Repair of Spinal Cord Injury and Brain Inflammation. — PubMed · 2025 · Journal Article
- Therapeutic potential of EVs loaded with CB2 receptor agonist in spinal cord injury via the Nrf2/HO-1 pathway. — PubMed · 2024 · Journal Article
- Bone marrow mesenchymal stem cells-derived exosomes promote spinal cord injury repair through the miR-497-5p/TXNIP/NLRP3 axis. — PubMed · 2024 · Journal Article
- A Functionalized Scaffold Facilitates Neurites Extension for Spinal Cord Injury Therapy. — PubMed · 2024 · Journal Article
- BMSC-Derived Exosomes Carrying miR-26a-5p Ameliorate Spinal Cord Injury via Negatively Regulating EZH2 and Activating the BDNF-TrkB-CREB Signaling. — PubMed · 2024 · Journal Article
- Epidermal Neural Crest Stem Cell Conditioned Medium Enhances Spinal Cord Injury Recovery via PI3K/AKT-Mediated Neuronal Apoptosis Suppression. — PubMed · 2024 · Journal Article
- BMSC-derived exosomal miR-219-5p alleviates ferroptosis in neuronal cells caused by spinal cord injury via the UBE2Z/NRF2 pathway. — PubMed · 2024 · Journal Article
- M2 Microglia-derived Exosomes Promote Spinal Cord Injury Recovery in Mice by Alleviating A1 Astrocyte Activation. — PubMed · 2024 · Journal Article
- Ginsenoside Rg1 Regulates Immune Microenvironment and Neurological Recovery After Spinal Cord Injury Through MYCBP2 Delivery via Neuronal Cell-Derived Extracellular Vesicles. — PubMed · 2024 · Journal Article
- Optical imaging detection of extracellular vesicles of miR-146 modified bone marrow mesenchymal stem cells promoting spinal cord injury repair. — PubMed · 2024 · Journal Article
- Schwann Cell-Derived Exosomes Induced Axon Growth after Spinal Cord Injury by Decreasing PTP-σ Activation on CSPGs via the Rho/ROCK Pathway. — PubMed · 2024 · Journal Article
- Spinal cord injury disrupts plasma extracellular vesicles cargoes leading to neuroinflammation in the brain and neurological dysfunction in aged male mice. — PubMed · 2024 · Journal Article
- Platelet-rich plasma-derived exosomes promote blood-spinal cord barrier repair and attenuate neuroinflammation after spinal cord injury. — PubMed · 2024 · Journal Article
- IPSC-NSCs-derived exosomal let-7b-5p improves motor function after spinal cord Injury by modulating microglial/macrophage pyroptosis. — PubMed · 2024 · Journal Article
- Exosomes derived from vMIP-II-Lamp2b gene-modified M2 cells provide neuroprotection by targeting the injured spinal cord, inhibiting chemokine signals and modulating microglia/macrophage polarization in mice. — PubMed · 2024 · Journal Article
- Exosomes from hypoxic ADSCs ameliorate neuronal damage post spinal cord injury through circ-Wdfy3 delivery and inhibition of ferroptosis. — PubMed · 2024 · Journal Article
- Extracellular vesicles containing miR-181a-5p as a novel therapy for experimental autoimmune encephalomyelitis-induced demyelination. — PubMed · 2024 · Journal Article
- Spinal Lymphatic Dysfunction Aggravates the Recovery Process After Spinal Cord Injury. — PubMed · 2024 · Journal Article
- MSC-derived exosomes deliver ZBTB4 to mediate transcriptional repression of ITIH3 in astrocytes in spinal cord injury. — PubMed · 2024 · Journal Article
- Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats. — PubMed · 2024 · Journal Article
- Intranasal delivery of small extracellular vesicles from specific subpopulation of mesenchymal stem cells mitigates traumatic spinal cord injury. — PubMed · 2024 · Journal Article
- Myeloid Cell Association with Spinal Cord Injury-Induced Neuropathic Pain and Depressive-like Behaviors in LysM-eGFP Mice. — PubMed · 2024 · Journal Article
- Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway. — PubMed · 2024 · Journal Article
- Sex Dependent Disparities in the Central Innate Immune Response after Moderate Spinal Cord Contusion in Rat. — PubMed · 2024 · Journal Article
- Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Promote the Recovery of Spinal Cord Injury and Inhibit Ferroptosis by Inactivating IL-17 Pathway. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 963561 · this programme has 49 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 12 · this programme has 639 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("extracellular vesicle" OR "exosome" OR "conditioned medium" OR "secretome") - Crossref
spinal cord injury extracellular vesicle exosome - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Extracellular Vesicles"[MeSH Terms] OR "Exosomes"[MeSH Terms] OR "extracellular vesicle"[Title/Abstract] OR "exosome"[Title/Abstract] OR "conditioned medium"[Title/Abstract] OR "secretome"[Title/Abstract])