A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Exosomes Derived from Tanshinone IIA-Pretreated Umbilical Cord Mesenchymal Stem Cells Repair Traumatic Spinal Cord Injury by miR-223-5p/USP8/NLRP3 Axis. — PubMed · 2025 · Journal Article
- The efficacy and pharmacological mechanisms of traditional Chinese medicine in the treatment of spinal cord injury. — PubMed · 2025 · Journal Article
- Current Concepts in Neurogenic Heterotopic Ossification. — PubMed · 2025 · Journal Article
- Neuroprotective Potential of Curcumin in Neurodegenerative Diseases: Clinical Insights Into Cellular and Molecular Signaling Pathways. — PubMed · 2025 · Journal Article
- Targeting JAK/STAT signaling pathway by curcumin: implications for spinal cord injury neuroprotection. — PubMed · 2025 · Journal Article
- Repeated Pressure and Shear Stress at the Posterior Heel Following Localized Skin Cooling: Protocol for a Repeated Measures Cohort Study. — PubMed · 2025 · Journal Article
- Chrysin's anti-inflammatory action in the central nervous system: A scoping review and an evidence-gap mapping of its mechanisms. — PubMed · 2025 · Journal Article
- Schwann Cells and Their Exosomes: Research Progress and Prospect in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Multi-omics analysis identified and confirmed TNF-α as a key initiator of the inflammatory response following spinal cord injury. — PubMed · 2025 · Journal Article
- Research landscape and trends of human umbilical cord mesenchymal stem cell-derived exosomes. — PubMed · 2025 · Journal Article
- Rewiring the Spine-Cutting-Edge Stem Cell Therapies for Spinal Cord Repair. — PubMed · 2025 · Journal Article
- Autophagy modulation by hADSCs and green light therapy alleviates inflammation and promotes functional recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases. — PubMed · 2025 · Journal Article
- Effects of Uro-Vaxom vs. placebo on the urinary tract microbiome in individuals with spinal cord injury in a randomized controlled pilot trial (Uro-Vaxom pilot). — PubMed · 2025 · Journal Article
- Repulsive Guidance Molecule-A as a Therapeutic Target Across Neurological Disorders: An Update. — PubMed · 2025 · Journal Article
- Human dental pulp stem cells for spinal cord injury. — PubMed · 2025 · Journal Article
- Local delivery of mesenchymal stem cell-extruded nanovesicles through a bio-responsive scaffold for acute spinal cord injury treatment. — PubMed · 2025 · Journal Article
- 50 years of methylprednisolone application in spinal cord injury: a bibliometric analysis. — PubMed · 2025 · Journal Article
- A biomimetic injectable chitosan/alginate hydrogel biocopmosites encapsulating selenium- folic acid nanoparticles for regeneration of spinal cord injury: An in vitro study. — PubMed · 2025 · Journal Article
- Clinical Efficacy of Ganglioside Combined with Methylprednisolone in the Treatment of Spinal Cord Injury and Its Effect on Inflammatory Response and Oxidative Stress Factors. — PubMed · 2025 · Journal Article
- Sirtuin1 in Spinal Cord Injury: Regulatory Mechanisms, Microenvironment Remodeling and Therapeutic Potential. — PubMed · 2025 · Journal Article
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Inflammation and Depression Following SCI — ClinicalTrials.gov · 2025 · Interventional · Unknown
- Interaction of microglia with the microenvironment in spinal cord injury. — PubMed · 2025 · Journal Article
- Spatial distribution-based progression of spinal cord injury pathology: a key role for neuroimmune cells. — PubMed · 2025 · Journal Article
- Exploring the Effectiveness and Potential Pharmacological Mechanism of Minocycline for Spinal Cord Injury through Meta-Analysis and Network Pharmacology. — PubMed · 2025 · Journal Article
- Mesenchymal Stem Cells and Their Extracellular Vesicles: Therapeutic Mechanisms for Blood-Spinal Cord Barrier Repair Following Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Physicochemical Property Effects on Immune Modulating Polymeric Nanoparticles: Potential Applications in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Saffron and its major constituents against neurodegenerative diseases: A mechanistic review. — PubMed · 2024 · Journal Article
- The macrophage migration inhibitory factor/CD74 axis in traumatic spinal cord injury: lessons learned from animal and human studies. — PubMed · 2024 · Journal Article
- Therapeutic potential of melatonin-pretreated human dental pulp stem cells (hDPSCs) in an animal model of spinal cord injury. — PubMed · 2024 · Journal Article
- The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases. — PubMed · 2024 · Journal Article
- The anti-inflammatory and immunomodulatory effects of olfactory ensheathing cells transplantation in spinal cord injury and concomitant pathological pain. — PubMed · 2024 · Journal Article
- Interleukin-6 in Spinal Cord Injury: Could Immunomodulation Replace Immunosuppression in the Management of Acute Traumatic Spinal Cord Injuries? — PubMed · 2024 · Journal Article
- Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives. — PubMed · 2024 · Journal Article
- OTULIN Can Improve Spinal Cord Injury by the NF-κB and Wnt/β-Catenin Signaling Pathways. — PubMed · 2024 · Journal Article
- Identification of immune-related hub genes in spinal cord injury. — PubMed · 2024 · Journal Article
- Enhanced spinal cord repair using bioengineered induced pluripotent stem cell-derived exosomes loaded with miRNA. — PubMed · 2024 · Journal Article
- Exosomes as promising bioactive materials in the treatment of spinal cord injury. — PubMed · 2024 · Journal Article
- Research Progress on Treating Spinal Cord Injury by Modulating the Phenotype of Microglia. — PubMed · 2024 · Journal Article
- The involvement and significance of M2 macrophages in neuropathic pain following spinal cord injury: a systematic review. — PubMed · 2024 · Journal Article
- Effects of ADSC-Derived Exosome LRRC75A-AS1 on Anti-inflammatory Function After SCI. — PubMed · 2024 · Journal Article
- Zinc ions regulate mitochondrial quality control in neurons under oxidative stress and reduce PANoptosis in spinal cord injury models via the Lgals3-Bax pathway. — PubMed · 2024 · Journal Article
- Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery. — PubMed · 2024 · Journal Article
- S100A9 Induces Macrophage M2 Polarization and Immunomodulatory Role in the Lesion Site After Spinal Cord Injury in Rats. — PubMed · 2024 · Journal Article
- The regulating effect of curcumin on NF-κB pathway in neurodegenerative diseases: a review of the underlying mechanisms. — PubMed · 2024 · Journal Article
- Human induced pluripotent stem cell/embryonic stem cell-derived pyramidal neuronal precursors show safety and efficacy in a rat spinal cord injury model. — PubMed · 2024 · Journal Article
- Umbilical cord blood derived cell expansion: a potential neuroprotective therapy. — PubMed · 2024 · Journal Article
- Stem cell therapies for neurological disorders: current progress, challenges, and future perspectives. — PubMed · 2024 · Journal Article
- Systemic Inflammatory Changes in Spinal Cord Injured Patients after Adding Aquatic Therapy to Standard Physiotherapy Treatment. — PubMed · 2024 · Journal Article
- A case of iatrogenic acute spinal cord injury with tetraplegia following thyroid surgery. — PubMed · 2024 · Case Reports
- Zein-Based Triple-Drug Nanoparticles to Promote Anti-Inflammatory Responses for Nerve Regeneration after Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype. — PubMed · 2024 · Journal Article
- Bioactivities of morroniside: A comprehensive review of pharmacological properties and molecular mechanisms. — PubMed · 2024 · Journal Article
- Stem cell exosome-loaded Gelfoam improves locomotor dysfunction and neuropathic pain in a rat model of spinal cord injury. — PubMed · 2024 · Journal Article
- An evaluation of the effects of localised skin cooling on microvascular, inflammatory, structural, and perceptual responses to sustained mechanical loading of the sacrum: A study protocol. — PubMed · 2024 · Journal Article
- The Molecular Biological Mechanism of Hydrogen Therapy and Its Application in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Human Adipose Tissue Lysate-Based Hydrogel for Lasting Immunomodulation to Effectively Improve Spinal Cord Injury Repair. — PubMed · 2024 · Journal Article
- Modulation of Inflammatory Responses to Enhance Nerve Recovery after Spinal Cord Injury. — PubMed · 2024 · Editorial
- α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes. — PubMed · 2024 · Journal Article
- α-Gal Nanoparticles in CNS Trauma: I. In Vitro Activation of Microglia Towards a Pro-Healing State. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 13 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1741999 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 17 · this programme has 2063 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])