A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Mesenchymal stem cell-derived small extracellular vesicles in spinal cord injury: From molecular repair mechanisms to standardized translational development. — PubMed · 2026 · Journal Article
- Soft substrate priming erases fibrotic mechanical memory in mesenchymal stromal cells via YAP lysosomal degradation to improve therapeutic efficacy for spinal cord injury. — PubMed · 2026 · Journal Article
- Exosome-mediated macrophage polarization: advances in immunotherapeutic paradigms and mechanisms in skeletal system diseases. — PubMed · 2026 · Journal Article
- Recent advances in fucoidan for stem cell protection and regenerative tissue repair. — PubMed · 2026 · Journal Article
- Role of Pattern Recognition Receptors (PRRs) in Spinal Cord Injury (SCI): A Comprehensive Review. — PubMed · 2026 · Journal Article
- Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Neuropathic Pain Following Spinal Cord Injury — ClinicalTrials.gov · 2026 · Interventional · Not Yet Recruiting
- IL-33/ST2 Signaling and Microglial Functional-State Transitions After Spinal Cord Injury: Direct Evidence and Mechanistic Hypotheses. — PubMed · 2026 · Journal Article
- Multi-time-point controlled-release methylprednisolone composite scaffolds based on clinical benchmarking for promoting spinal cord injury repair. — PubMed · 2026 · Journal Article
- Beyond Scar Removal: Reprogramming the Glial Scar for Neural Repair. — PubMed · 2026 · Journal Article
- Alkaloids as Emerging Neuroprotective Agents for Neurodegenerative Disorders: Insights into Tryptanthrin and Its Derivatives. — PubMed · 2026 · Journal Article
- Andrograpanin attenuates secondary neuroinflammation after spinal cord injury by modulating microglial glycolysis via HIF-1α. — PubMed · 2026 · Journal Article
- Bioinspired hydrogel remodels the niche after spinal cord injury for neural reconnection by promoting angiogenesis and reducing inflammation. — PubMed · 2026 · Journal Article
- Targeting Neurodegeneration With Naringenin: Mechanistic Perspectives and Therapeutic Implications. — PubMed · 2026 · Journal Article
- The Pleiotropic Therapeutic Perspectives of GLP-1 and GIP Receptor Agonists in Spinal Cord Injury: A Narrative Review. — PubMed · 2026 · Journal Article
- Research Progress on Regulating Neuroinflammation After Spinal Cord Injury by Targeting the cGAS-STING Pathway. — PubMed · 2026 · Journal Article
- The Immunologic Function of the Choroid Plexus: A Gateway to Immunomodulatory Therapy in Injury Models of the Central Nervous System. — PubMed · 2026 · Journal Article
- Remarkable Recovery After Delayed High-Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury. — PubMed · 2026 · Case Reports
- Mechanisms ofra Tetmethylpyrazine in spinal cord injury: a narrative review. — PubMed · 2026 · Journal Article
- Mechanistic interactions between curcumin and statins: pharmacological convergence and therapeutic implications. — PubMed · 2026 · Journal Article
- Repurposing tumor-derived extracellular vesicles with an adhesive carboxymethyl chitosan-based hydrogel for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Translational potential of GMP-grade human umbilical cord-derived mesenchymal stem cells (UC-MSCs) in traumatic spinal cord injury: a preclinical study in rat. — PubMed · 2026 · Journal Article
- EmpowerSpine Program — ClinicalTrials.gov · 2026 · Interventional · Not Yet Recruiting
- Mechanisms and therapeutic potential of hydrogen sulfide in traumatic central nervous system injuries. — PubMed · 2026 · Journal Article
- Riluzole in neuroinflammation and neurodegeneration: Mechanistic insights and experimental validation. — PubMed · 2026 · Journal Article
- Coacervates Made of Elastin-Like Polypeptides Fused with Melanocyte-Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord-Injured Mice. — PubMed · 2026 · Journal Article
- Targeting Neuroinflammatory and Regenerative Pathways with Monoclonal Antibodies in Spinal Cord Injury: A Bibliometric Analysis. — PubMed · 2026 · Journal Article
- The Pivotal Roles of Macrophages and Microglia in Mesenchymal Stromal/Stem Cell-Derived Small Extracellular Vesicle-Mediated Tissue Repair After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Neuropathic Pain Severity Is Associated With Opioid Use in Adults With Traumatic Spinal Cord Injury: A Spinal Cord Injury Model System Study. — PubMed · 2026 · Journal Article
- Reprogramming the Inflammatory Response to Promote Neural Stem Cell Function After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- From medicinal herb to neuroprotective candidate: A review of curculigoside's potential in central nervous system disorders. — PubMed · 2026 · Journal Article
- Injectable hydrogel-based localized delivery of IDO-galectin-3 mitigates neuroinflammation and promotes neuronal sparing after spinal cord contusion in rats. — PubMed · 2026 · Journal Article
- Application of hyperbaric oxygen therapy in the treatment of spinal cord injury: insights from preclinical to clinical evidence. — PubMed · 2026 · Journal Article
- Neural Stem Cells and Inflammation Modulation in Preclinical Spinal Cord Injury: A Systematic Review. — PubMed · 2026 · Journal Article
- Systemic Interleukin-4 Application Promotes Functional Recovery and Reprograms Neuroinflammatory and Molecular Responses after Spinal Cord Injury in Rats. — PubMed · 2026 · Journal Article
- Beyond exercise and appetite: The expanding biology and therapeutic potential of N-lactoyl-phenylalanine. — PubMed · 2026 · Journal Article
- The main signaling pathways determining the microglia responses in spinal cord injury: Potential effectors among known pharmaceuticals. — PubMed · 2026 · Journal Article
- Intravesical instillation of pirfenidone/polydopamine nanoparticles for managing neurogenic bladder post-spinal cord injury by alleviating bladder inflammation and fibrosis. — PubMed · 2026 · Journal Article
- The effects of electrical stimulation on neurons and glia of the central nervous system. — PubMed · 2026 · Journal Article
- Progress on Omega-3 fatty acids for the comprehensive and targeted treatment of spinal cord injury. — PubMed · 2026 · Journal Article
- Lac-Phe: An Emerging Appetite-Regulating Exerkine with Health and Therapeutic Benefits. — PubMed · 2026 · Journal Article
- Effects of an Adaptive Exercise Program on Inflammation After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Nanoengineered Niclosamide as a Microenvironment Modulator for Spinal Cord Regeneration: A Hypothetical Roadmap Toward Brain/Head Transplant Feasibility. — PubMed · 2026 · Journal Article
- Mechanism analysis and intervention strategies of the inflammatory microenvironment in traumatic spinal cord injury. — PubMed · 2025 · Journal Article
- The role of polarization dynamics in macrophages and microglia on the inflammatory microenvironment of spinal cord injury. — PubMed · 2025 · Journal Article
- The impact of histone deacetylase inhibition on neurobehavioural outcomes in preclinical models of traumatic and non-traumatic spinal cord injury: a systematic review. — PubMed · 2025 · Journal Article
- Enhancing clinical translation of analgesics for neuropathic pain: a systematic review and meta-analysis on the role of non-evoked pain assessment in preclinical trials. — PubMed · 2025 · Journal Article
- Enhancing spinal cord injury recovery with functional liposomal nanomedicine: A neuroprotective and anti-inflammatory approach. — PubMed · 2025 · Journal Article
- Roles for Exosomes from Various Cellular Sources in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Immune Activation Following Spinal Cord Injury: A Review Focused on Inflammatory Changes in the Spinal Cord. — PubMed · 2025 · Journal Article
- Adipose-derived stem cell exosomes: multifaceted therapeutic applications in regenerative medicine. — PubMed · 2025 · Journal Article
- Biodegradable and anti-swelling peptide-based supermolecule hydrogel for eliminating ROS and inhibiting inflammation in acute spinal cord injury repair. — PubMed · 2025 · Journal Article
- Exosome Therapy: A Promising Avenue for Treating Intervertebral Disc Degeneration. — PubMed · 2025 · Journal Article
- Immunomodulation for Primary Prevention of Urinary Tract Infections in Patients With Spinal Cord Injury or Disease During Primary In-House Rehabilitation: Results From a Randomized Placebo-Controlled Feasibility Trial (UroVaxom-Pilot). — PubMed · 2025 · Journal Article
- Pharmacological landscape of linarin: From benchside mechanisms to potential bedside applications. — PubMed · 2025 · Journal Article
- Mechanisms and parameters of photobiomodulation for neurological and neuropsychiatric disorders: whether and how to apply? — PubMed · 2025 · Journal Article
- Multidimensional Engineering of Extracellular Vesicles for Targeted Delivery and Microglial Reprograming in Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
- Association Between Spinal Cord Injury and Cognitive Impairment, and the Mediating Role of Inflammation. — PubMed · 2025 · Journal Article
- Intermittent Fasting for Inflammation and Depression in Spinal Cord Injury — ClinicalTrials.gov · 2025 · Interventional · Not Yet Recruiting
- Regulatory effect of inflammatory mediators in spinal cord injury. — PubMed · 2025 · Journal Article
- Human iPSC-derived spinal neural progenitors enhance sensorimotor recovery in spinal cord-injured NOD-SCID mice via differentiation and microenvironment regulation. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 13 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1741999 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 17 · this programme has 2063 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])