A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Multipotent adult progenitor cells prevent macrophage-mediated axonal dieback and promote regrowth after spinal cord injury. — PubMed · 2011 · Journal Article
- The glial scar-monocyte interplay: a pivotal resolution phase in spinal cord repair. — PubMed · 2011 · Journal Article
- The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. — PubMed · 2010 · Journal Article
- "Tissue-repairing" blood-derived macrophages are essential for healing of the injured spinal cord: from skin-activated macrophages to infiltrating blood-derived cells? — PubMed · 2010 · Journal Article
- Endogenous expression of interleukin-4 regulates macrophage activation and confines cavity formation after traumatic spinal cord injury. — PubMed · 2010 · Journal Article
- Anti-IL-6-receptor antibody promotes repair of spinal cord injury by inducing microglia-dominant inflammation. — PubMed · 2010 · Journal Article
- NgR expression in macrophages promotes nerve regeneration after spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Embryonic stem cells promote motor recovery and affect inflammatory cell infiltration in spinal cord injured mice. — PubMed · 2010 · Journal Article
- Postinjury estrogen treatment of chronic spinal cord injury improves locomotor function in rats. — PubMed · 2010 · Journal Article
- ProBDNF inhibits infiltration of ED1+ macrophages after spinal cord injury. — PubMed · 2010 · Journal Article
- The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury. — PubMed · 2010 · Journal Article
- Separation of the perivascular basement membrane provides a conduit for inflammatory cells in a mouse spinal cord injury model. — PubMed · 2010 · Journal Article
- Expression of galectin-1 in immune cells and glial cells after spinal cord injury. — PubMed · 2010 · Journal Article
- Myelin activates FAK/Akt/NF-kappaB pathways and provokes CR3-dependent inflammatory response in murine system. — PubMed · 2010 · Journal Article
- Reducing macrophages to improve bone marrow stromal cell survival in the contused spinal cord. — PubMed · 2010 · Journal Article
- Comparison of immunopathology and locomotor recovery in C57BL/6, BUB/BnJ, and NOD-SCID mice after contusion spinal cord injury. — PubMed · 2010 · Comparative Study
- Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment. — PubMed · 2010 · Comparative Study
- Adult NG2+ cells are permissive to neurite outgrowth and stabilize sensory axons during macrophage-induced axonal dieback after spinal cord injury. — PubMed · 2010 · Comparative Study
- Progranulin expression is upregulated after spinal contusion in mice. — PubMed · 2010 · Journal Article
- Inhibition of TGF-beta1 promotes functional recovery after spinal cord injury. — PubMed · 2009 · Journal Article
- Timing and duration of anti-alpha4beta1 integrin treatment after spinal cord injury: effect on therapeutic efficacy. — PubMed · 2009 · Journal Article
- Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. — PubMed · 2009 · Journal Article
- Overcoming macrophage-mediated axonal dieback following CNS injury. — PubMed · 2009 · Journal Article
- Arachidonyl trifluoromethyl ketone is neuroprotective after spinal cord injury. — PubMed · 2009 · Journal Article
- The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury. — PubMed · 2009 · Journal Article
- High-dose corticosteroids after spinal cord injury reduce neural progenitor cell proliferation. — PubMed · 2009 · Journal Article
- Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice. — PubMed · 2009 · Journal Article
- Glial and axonal responses in areas of Wallerian degeneration of the corticospinal and dorsal ascending tracts after spinal cord dorsal funiculotomy. — PubMed · 2009 · Journal Article
- Activation of dendritic-like cells and neural stem/progenitor cells in injured spinal cord by GM-CSF. — PubMed · 2009 · Journal Article
- Dose and chemical modification considerations for continuous cyclic AMP analog delivery to the injured CNS. — PubMed · 2009 · Journal Article
- Deletion of macrophage migration inhibitory factor attenuates neuronal death and promotes functional recovery after compression-induced spinal cord injury in mice. — PubMed · 2009 · Journal Article
- Granulocyte-macrophage colony-stimulating factor promotes survival of dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced murine Parkinson's disease model. — PubMed · 2009 · Journal Article
- PAL31 may play an important role as inflammatory modulator in the repair process of the spinal cord injury rat. — PubMed · 2009 · Journal Article
- GM-CSF inhibits glial scar formation and shows long-term protective effect after spinal cord injury. — PubMed · 2009 · Journal Article
- Upregulation in rat spinal cord microglia of the nonintegrin laminin receptor 37 kDa-LRP following activation by a traumatic lesion or peripheral injury. — PubMed · 2009 · Journal Article
- Neuropathic pain behaviours in a chronic-relapsing model of experimental autoimmune encephalomyelitis (EAE). — PubMed · 2009 · Journal Article
- The endocannabinoid system is modulated in response to spinal cord injury in rats. — PubMed · 2009 · Journal Article
- Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury. — PubMed · 2008 · Journal Article
- Alpha4beta1 integrin blockade after spinal cord injury decreases damage and improves neurological function. — PubMed · 2008 · Journal Article
- An integrin inhibiting molecule decreases oxidative damage and improves neurological function after spinal cord injury. — PubMed · 2008 · Journal Article
- Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1. — PubMed · 2008 · Journal Article
- Spinal cord injury-induced immunodepression syndrome. — PubMed · 2008 · Editorial
- Robust axonal growth and a blunted macrophage response are associated with impaired functional recovery after spinal cord injury in the MRL/MpJ mouse. — PubMed · 2008 · Comparative Study
- Liver Kupffer cells control the magnitude of the inflammatory response in the injured brain and spinal cord. — PubMed · 2008 · Journal Article
- Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions. — PubMed · 2008 · Journal Article
- Spinal cord injury causes rapid osteoclastic resorption and growth plate abnormalities in growing rats (SCI-induced bone loss in growing rats). — PubMed · 2008 · Journal Article
- The systemic inflammatory response after spinal cord injury damages lungs and kidneys. — PubMed · 2008 · Journal Article
- Detrimental effects of antiapoptotic treatments in spinal cord injury. — PubMed · 2008 · Journal Article
- Mechanistic insights into posttraumatic syringomyelia based on a novel in vivo animal model. Laboratory investigation. — PubMed · 2008 · Journal Article
- Combined treatment using peripheral nerve graft and FGF-1: changes to the glial environment and differential macrophage reaction in a complete transected spinal cord. — PubMed · 2008 · Journal Article
- The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. — PubMed · 2008 · Journal Article
- Delayed accumulation of activated macrophages and inhibition of remyelination after spinal cord injury in an adult rodent model. — PubMed · 2008 · Journal Article
- Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat. — PubMed · 2008 · Journal Article
- Selenium attenuates ROS-mediated apoptotic cell death of injured spinal cord through prevention of mitochondria dysfunction; in vitro and in vivo study. — PubMed · 2008 · Journal Article
- A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury. — PubMed · 2007 · Comparative Study
- Evaluation of cellular organization and axonal regeneration through linear PLA foam implants in acute and chronic spinal cord injury. — PubMed · 2007 · Journal Article
- The extent of myelin pathology differs following contusion and transection spinal cord injury. — PubMed · 2007 · Journal Article
- Reparixin, an inhibitor of CXCR2 function, attenuates inflammatory responses and promotes recovery of function after traumatic lesion to the spinal cord. — PubMed · 2007 · Journal Article
- Distinct types of microglial activation in white and grey matter of rat lumbosacral cord after mid-thoracic spinal transection. — PubMed · 2007 · Journal Article
- Lithium enhances proliferation and neuronal differentiation of neural progenitor cells in vitro and after transplantation into the adult rat spinal cord. — PubMed · 2007 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])