A subject this map covers
Nanoparticle delivery
Part of: Biomaterials
What belongs here
Nanometre-scale carriers delivering drug, gene or signal to the injury.
What does not belong here, however close it looks
A nanostructured scaffold with no delivery role is a scaffold.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 257 records · 1989–2026
- Indexed as work in animals: 327 records · 1999–2026
- Indexed as laboratory work: 46 records · 2005–2026
- The source has not said who or what was studied: 112 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
742 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- The effect of long-term release of Shh from implanted biodegradable microspheres on recovery from spinal cord injury in mice. — PubMed · 2012 · Journal Article
- A re-assessment of the effects of intracortical delivery of inosine on transmidline growth of corticospinal tract axons after unilateral lesions of the medullary pyramid. — PubMed · 2012 · Comparative Study
- Biodegradable nanoparticles for protein delivery: analysis of preparation conditions on particle morphology and protein loading, activity and sustained release properties. — PubMed · 2012 · Journal Article
- Highly efficient magnetic targeting of mesenchymal stem cells in spinal cord injury. — PubMed · 2012 · Journal Article
- A pilot study of poly(N-isopropylacrylamide)-g-polyethylene glycol and poly(N-isopropylacrylamide)-g-methylcellulose branched copolymers as injectable scaffolds for local delivery of neurotrophins and cellular transplants into the injured spinal cord. — PubMed · 2011 · Journal Article
- Magnetic nanoparticle-mediated gene transfer to oligodendrocyte precursor cell transplant populations is enhanced by magnetofection strategies. — PubMed · 2011 · Journal Article
- Therapeutic effects with magnetic targeting of bone marrow stromal cells in a rat spinal cord injury model. — PubMed · 2011 · Comparative Study
- Sustained delivery of dibutyryl cyclic adenosine monophosphate to the transected spinal cord via oligo [(polyethylene glycol) fumarate] hydrogels. — PubMed · 2011 · Journal Article
- Proteins conjugated to poly(butyl cyanoacrylate) nanoparticles as potential neuroprotective agents. — PubMed · 2011 · Journal Article
- [Study of TAT-PEG loaded magnetic liposomes crossing blood spinal cord barrier after spinal cord injury in rats]. — PubMed · 2011 · Journal Article
- Morphologic changes associated with intrathecal catheters for direct delivery to the central nervous system in preclinical studies. — PubMed · 2011 · Comparative Study
- Nano PGE1 promoted the recovery from spinal cord injury-induced motor dysfunction through its accumulation and sustained release. — PubMed · 2010 · Journal Article
- Controlled release of chondroitinase ABC from fibrin gel reduces the level of inhibitory glycosaminoglycan chains in lesioned spinal cord. — PubMed · 2010 · Journal Article
- Novel multifunctional polyethylene glycol-transactivating-transduction protein-modified liposomes cross the blood-spinal cord barrier after spinal cord injury. — PubMed · 2010 · Journal Article
- Poly(ethylene glycol) modification enhances penetration of fibroblast growth factor 2 to injured spinal cord tissue from an intrathecal delivery system. — PubMed · 2010 · Journal Article
- Functional silica nanoparticle-mediated neuronal membrane sealing following traumatic spinal cord injury. — PubMed · 2010 · Journal Article
- Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injury. — PubMed · 2010 · Journal Article
- Nanowired-drug delivery enhances neuroprotective efficacy of compounds and reduces spinal cord edema formation and improves functional outcome following spinal cord injury in the rat. — PubMed · 2010 · Journal Article
- Silicon dioxide nanoparticles (SiO2, 40-50 nm) exacerbate pathophysiology of traumatic spinal cord injury and deteriorate functional outcome in the rat. An experimental study using pharmacological and morphological approaches. — PubMed · 2009 · Journal Article
- Nanoparticle-mediated local delivery of Methylprednisolone after spinal cord injury. — PubMed · 2009 · Journal Article
- A new paradigm for local and sustained release of therapeutic molecules to the injured spinal cord for neuroprotection and tissue repair. — PubMed · 2009 · Journal Article
- Uptake of systemically administered magnetic nanoparticles (MNPs) in areas of experimental spinal cord injury (SCI). — PubMed · 2009 · Journal Article
- Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury. — PubMed · 2008 · Journal Article
- Repairing the damaged spinal cord and brain with nanomedicine. — PubMed · 2008 · Journal Article
- Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord. — PubMed · 2008 · Journal Article
- Drug delivery to the spinal cord tagged with nanowire enhances neuroprotective efficacy and functional recovery following trauma to the rat spinal cord. — PubMed · 2007 · Journal Article
- Delayed release particles from vascular endothelial growth factor for repairing spinal cord ischemic injury of rats. — PubMed · 2007 · Journal Article
- Effect of controlled delivery of neurotrophin-3 from fibrin on spinal cord injury in a long term model. — PubMed · 2006 · Comparative Study
- An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury. — PubMed · 2006 · Journal Article
- Magnetic targeting of bone marrow stromal cells into spinal cord: through cerebrospinal fluid. — PubMed · 2006 · Comparative Study
- Delivery of neurotrophin-3 from fibrin enhances neuronal fiber sprouting after spinal cord injury. — PubMed · 2006 · Comparative Study
- Lecithinized superoxide dismutase (PC-SOD) improved spinal cord injury-induced motor dysfunction through suppression of oxidative stress and enhancement of neurotrophic factor production. — PubMed · 2006 · Journal Article
- In situ gelling hydrogels for conformal repair of spinal cord defects, and local delivery of BDNF after spinal cord injury. — PubMed · 2006 · Journal Article
- Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection. — PubMed · 2006 · Journal Article
- Controlled release of neurotrophin-3 from fibrin gels for spinal cord injury. — PubMed · 2004 · Journal Article
- Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord. — PubMed · 2004 · Comparative Study
- Freeze-dried poly(D,L-lactic acid) macroporous guidance scaffolds impregnated with brain-derived neurotrophic factor in the transected adult rat thoracic spinal cord. — PubMed · 2004 · Comparative Study
- Restriction of axonal retraction and promotion of axonal regeneration by chronically injured neurons after intraspinal treatment with glial cell line-derived neurotrophic factor (GDNF). — PubMed · 2003 · Comparative Study
- Remyelination of the spinal cord following intravenous delivery of bone marrow cells. — PubMed · 2002 · Journal Article
- Convection-enhanced delivery in intact and lesioned peripheral nerve. — PubMed · 2001 · Journal Article
- Adenovirus-mediated glial cell line-derived neurotrophic factor gene delivery reduces motor neuron injury after transient spinal cord ischemia in rabbits. — PubMed · 2000 · Journal Article
- Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. — PubMed · 1999 · Journal Article
- Alpha-melanocyte stimulating hormone promotes regrowth of injured axons in the adult rat spinal cord. — PubMed · 1999 · Journal Article
- Delivering neuroactive molecules from biodegradable microspheres for application in central nervous system disorders. — PubMed · 1999 · Journal Article
Indexed as laboratory work
- Smart alginate-based biomaterials for neurodegenerative disease therapy: Innovations in delivery, regeneration, and clinical translation. — PubMed · 2026 · Journal Article
- Engineering integrin αvβ8-targeted extracellular vesicles to deliver BDNF mRNA for motor recovery in spinal cord injury. — PubMed · 2026 · Journal Article
- Advancements in Spinal Cord Injury Treatment: Integrating Drug Delivery, Biophysical Stimulation, Cell-Based Therapies, and Tissue Engineering Approaches. — PubMed · 2025 · Journal Article
- Bioactive Three-Dimensional Chitosan-Based Scaffolds Modified with Poly(dopamine)/CBD@Pt/Au/PVP Nanoparticles as Potential NGCs Applicable in Nervous Tissue Regeneration-Preparation and Characterization. — PubMed · 2024 · Journal Article
- miR-NPs-RVG promote spinal cord injury repair: implications from spinal cord-derived microvascular endothelial cells. — PubMed · 2024 · Journal Article
- Electrospun drug-loaded scaffolds for nervous system repair. — PubMed · 2024 · Journal Article
- Construction and optimization of a coculture system of mouse brain microvascular endothelial cells and myelin debris. — PubMed · 2023 · Journal Article
- 3D printable Sodium alginate-Matrigel (SA-MA) hydrogel facilitated ectomesenchymal stem cells (EMSCs) neuron differentiation. — PubMed · 2021 · Journal Article
- Recent Advances in the Regenerative Approaches for Traumatic Spinal Cord Injury: Materials Perspective. — PubMed · 2020 · Journal Article
- Bidirectional Enhancement of Cell Proliferation Between Iron Oxide Nanoparticle-Labeled Mesenchymal Stem Cells and Choroid Plexus in a Cell-Based Therapy Model of Ischemic Stroke. — PubMed · 2020 · Journal Article
- Docosahexaenoic Acid-Loaded Polylactic Acid Core-Shell Nanofiber Membranes for Regenerative Medicine after Spinal Cord Injury: In Vitro and In Vivo Study. — PubMed · 2020 · Journal Article
- Alginate Hydrogels as Scaffolds and Delivery Systems to Repair the Damaged Spinal Cord. — PubMed · 2019 · Journal Article
- Matrices, scaffolds & carriers for cell delivery in nerve regeneration. — PubMed · 2019 · Journal Article
- Combinatorial tissue engineering partially restores function after spinal cord injury. — PubMed · 2019 · Journal Article
- Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices. — PubMed · 2019 · Journal Article
- Promotion of neuronal regeneration by using self-polymerized dendritic polypeptide scaffold for spinal cord tissue engineering. — PubMed · 2017 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 947365 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 709 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("nanoparticle" OR "nanomedicine") - Crossref
spinal cord injury nanoparticle nanomedicine - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nanoparticles"[MeSH Terms] OR "Drug Delivery Systems"[MeSH Terms] OR "nanoparticle"[Title/Abstract] OR "nanomedicine"[Title/Abstract])