A subject this map covers
Nanoparticle delivery
Part of: Biomaterials
What belongs here
Nanometre-scale carriers delivering drug, gene or signal to the injury.
What does not belong here, however close it looks
A nanostructured scaffold with no delivery role is a scaffold.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 257 records · 1989–2026
- Indexed as work in animals: 327 records · 1999–2026
- Indexed as laboratory work: 46 records · 2005–2026
- The source has not said who or what was studied: 112 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
742 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Targeting neurite growth inhibitors to induce CNS regeneration. — PubMed · 2005 · Journal Article
- A low-dose radioisotope procedure for assessment of subcutaneous drug delivery systems used for slow intrathecal infusion of antispasmodic agents. — PubMed · 2004 · Journal Article
- Axonal responses to cellularly delivered NT-4/5 after spinal cord injury. — PubMed · 2004 · Journal Article
- Mitochondrial uncoupling as a therapeutic target following neuronal injury. — PubMed · 2004 · Journal Article
- Pharmacokinetics and safety of multiple oral doses of sustained-release 4-aminopyridine (Fampridine-SR) in subjects with chronic, incomplete spinal cord injury. — PubMed · 2004 · Clinical Trial
- Targeting the Nogo receptor to treat central nervous system injuries. — PubMed · 2003 · Journal Article
- Poly(ADP-ribosyl)ation enzyme-1 as a target for neuroprotection in acute central nervous system injury. — PubMed · 2003 · Journal Article
- Pharmacokinetic studies of single and multiple oral doses of fampridine-SR (sustained-release 4-aminopyridine) in patients with chronic spinal cord injury. — PubMed · 2003 · Comparative Study
- Biodegradable polymer grafts for surgical repair of the injured spinal cord. — PubMed · 2002 · Journal Article
- Spontaneous and augmented growth of axons in the primate spinal cord: effects of local injury and nerve growth factor-secreting cell grafts. — PubMed · 2002 · Journal Article
- Clodronate liposomes: perspectives in research and therapeutics. — PubMed · 2002 · Journal Article
- Absorption characteristics of sustained-release 4-aminopyridine (fampridine SR) in patients with chronic spinal cord injury. — PubMed · 2000 · Clinical Trial
- Bioavailability of trospium chloride after intravesical instillation in patients with neurogenic lower urinary tract dysfunction: A pilot study. — PubMed · 1999 · Clinical Trial
- Randomized double-blind crossover trial of fampridine-SR (sustained release 4-aminopyridine) in patients with incomplete spinal cord injury. — PubMed · 1998 · Clinical Trial
- Intrathecal baclofen--a multicentre clinical comparison of the Medtronics Programmable, Cordis Secor and Constant Infusion Infusaid drug delivery systems. — PubMed · 1995 · Clinical Trial
- Reduction in bowel program duration with polyethylene glycol based bisacodyl suppositories. — PubMed · 1995 · Case Reports
- Insulin pump treatment of type I diabetes mellitus in a patient with C6 quadriplegia. — PubMed · 1989 · Case Reports
Indexed as work in animals
- Dual-engineered imDC-exosome-IKVAV nanovesicles spatiotemporally remodel the neuro-immune microenvironment for spinal cord repair. — PubMed · 2026 · Journal Article
- Evaluation the antioxidant effects of scaffold containing curcumin nanoparticles in unilateral spinal cord injury model in the male rats. — PubMed · 2026 · Journal Article
- Nanoformulated fingolimod attenuates NLRP3 inflammasome activation and promotes functional recovery in a rat model of spinal cord injury. — PubMed · 2026 · Journal Article
- Quantum Photothermal Self-Monitoring Fiber Probes for In Vivo Photothermal Therapy. — PubMed · 2026 · Journal Article
- Targeting microglial MyD88 reprograms injury-activated microglia and promotes spinal cord repair via TGF-β signaling and biomimetic nanodelivery. — PubMed · 2026 · Journal Article
- Nanoparticle Modulation of Immune and Vascular Microenvironment Dynamics Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Cel-LDH dual-functional nanotherapy simultaneously promotes microglial efferocytosis and alleviates neuronal apoptosis for spinal cord injury recovery. — PubMed · 2026 · Journal Article
- Mesenchymal Stem Cell-Lysate Sustained-Release Nano-Hydrogel Alleviates Spinal Cord Injury by Inhibiting Ferroptosis and Mitochondrial Intrinsic Apoptosis. — PubMed · 2026 · Journal Article
- Impeding glial scarring hyperplasia and activating axon neogenesis via immunomodulatory microneedle patch for spinal cord repair. — PubMed · 2026 · Journal Article
- Sodium Alginate Hydrogel with Zinc Ion Nanoparticles for Synergistic Neuroprotection and Functional Recovery in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- An Iron-Scavenging and Hydrogen-Releasing Microneedle Patch Suppresses Ferroptosis and Promotes Spinal Cord Repair. — PubMed · 2026 · Journal Article
- Dual-targeting nanoparticles enhance microglial P2Y12R expression to promote neuronal mitophagy for repairing spinal cord injury. — PubMed · 2026 · Journal Article
- Spatiotemporal Co-Delivery of Hydrogen and Magnesium via Microneedle Patches for Neuroinflammation Modulation After Spinal Cord Injury: A Multi-Modal In Vivo Study. — PubMed · 2026 · Journal Article
- Injectable Metal-Free Carbon Dot-Integrated Hydrogel for Regulating Inflammation via Macrophage Metabolic Reprograming in Spinal Cord Injury Therapy. — PubMed · 2026 · Journal Article
- Matrix Metalloproteinase-Activatable Nanodrug Crossing Blood-Spinal Cord Barrier for On-Demand Drug Release in Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- A novel schisantherin B-loaded Prussian blue nanozyme for treating spinal cord injury. — PubMed · 2026 · Journal Article
- Focal Estrogen Therapy in Male Rats Promotes Neuronal Survival and Reduces Denervation Atrophy After Spinal Cord Injury via Modulation of β-Catenin and NF-κB. — PubMed · 2026 · Journal Article
- NanoScript-Enabled Nonviral Transient Repression of Phosphatase and Tensin Homolog for Axonal Regeneration and Central Nervous System Injury Repair. — PubMed · 2026 · Journal Article
- Green Synthesis, Chemical Characterization, and Assessment of the Neuroprotective Properties of Zinc Nanoparticles on the Spinal Cord Injury Contusive Model in Rats. — PubMed · 2026 · Journal Article
- Intracellular small molecule/ion storm from Ca-phytate nanoparticle synergizes neural stem cell therapy and immunomodulation in spinal cord injury. — PubMed · 2026 · Journal Article
- Sequential dual-drug delivery biomimetic hydrogel for temporal orchestration of acute neuroprotection and chronic regeneration in spinal cord injury. — PubMed · 2026 · Journal Article
- Nanoparticle-Assembled Multifaceted Hydrogel Therapy Promotes Functional Recovery After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- LPS Pre-Conditioned Olfactory Ensheathing Cells Derived Extracellular Vesicle Regulate Microglia Polarization Through mir-1224/CD44/SLC7A11 Axis Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- A dual-action nanoparticle approach for spinal cord injury treatment: ferroptosis inhibition, inflammation control, and Myelin preservation. — PubMed · 2026 · Journal Article
- Multifunctional Diselenide-Based Antioxidative Nanozymes Promote Spinal Cord Repair via Oxidative Stress Alleviation and Immune Modulation. — PubMed · 2026 · Journal Article
- A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Immuno-Neuroprotectants Facilitate Neurological Recovery via Sequestration of Neutrophil Extracellular Traps (NETs) and Promotion of Neuroregeneration. — PubMed · 2026 · Journal Article
- Local release of fibroblast growth factor 21 and cannabidiol promoting spinal cord nerve injury repair through activation of cannabinoid receptor 2. — PubMed · 2026 · Journal Article
- Targeting peptide homes to spinal cord injury in a rat model. — PubMed · 2026 · Journal Article
- A Novel Retrievable Drug Infusion Stent and Blood-Brain Barrier Portal for Antibody Therapies to the Spinal Cord. — PubMed · 2026 · Journal Article
- Development of a multifunctional, injectable biomaterial using hyaluronan as a bioactive nanocarrier. — PubMed · 2026 · Journal Article
- Lysine-polydopamine nanoparticles for ameliorating acidic microenvironment and neuroprotection in spinal cord injury repair. — PubMed · 2026 · Journal Article
- N-acetylcysteine loaded electrospun core/shell nanofibers: a promising system for ferroptosis in spinal cord injury. — PubMed · 2026 · Journal Article
- Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Neuroprotection and Axonal Regeneration via ECM-Mimetic Nanofibers Incorporating Metal-Phenolic Network Nanoparticles Toward Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- Uric Acid Released from Poly (Lactic-co-Glycolic Acid) Nanoparticles Mitigates Glutamate-Induced Excitotoxicity of Spinal Cord Neurons. — PubMed · 2026 · Journal Article
- Galantamine-loaded PLGA nanoparticles reduce oxidative stress and inflammation in a rat model of spinal cord injury. — PubMed · 2025 · Journal Article
- Precisely targeting of engineered nanovesicles to implanted scaffolds via click chemistry for microenvironment regulation in acute spinal cord injury. — PubMed · 2025 · Journal Article
- Cabazitaxel Sustained-Release Nanoparticles Treat Spinal Cord Injury through Inhibiting Fibrin Deposition and Improving the Microenvironment. — PubMed · 2025 · Journal Article
- Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of IL-10 for Effective Management of Peripheral and Central Neuropathic Pain in Rats. — PubMed · 2025 · Journal Article
- A Novel Long-Term Intrathecal Cannulation Technique in Rats: L5-L6 Approach With Cervical Externalization for Chronic Drug Delivery. — PubMed · 2025 · Journal Article
- A hydrogel-based nanoparticles sustained-release system selectively targeting pro-inflammatory microglia for spinal cord injury repair. — PubMed · 2025 · Journal Article
- β-Sheet-Assisted Fabrication of Drug-Loaded Gelatin/Silk Fibroin Nanoparticles for Spinal Cord Injury Treatment. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 947365 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 709 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("nanoparticle" OR "nanomedicine") - Crossref
spinal cord injury nanoparticle nanomedicine - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nanoparticles"[MeSH Terms] OR "Drug Delivery Systems"[MeSH Terms] OR "nanoparticle"[Title/Abstract] OR "nanomedicine"[Title/Abstract])