A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Biological interventions for spinal cord injury. — PubMed · 1998 · Journal Article
- [Research status and prospects of gene therapy in spinal cord injuries]. — PubMed · 1998 · English Abstract
- Preparation of brain-derived neurotrophic factor- and neurotrophin-3-secreting Schwann cells by infection with a retroviral vector. — PubMed · 1998 · Journal Article
- Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination. — PubMed · 1998 · Journal Article
- Neurotrophin gene therapy in CNS models of trauma and degeneration. — PubMed · 1998 · Journal Article
- Spinal cord injury: bridging the lesion and the role of neurotrophic factors in repair. — PubMed · 1998 · Journal Article
- Functional characterization of NGF-secreting cell grafts to the acutely injured spinal cord. — PubMed · 1997 · Journal Article
- Regeneration of injured axons in the adult mammalian central nervous system. — PubMed · 1997 · Journal Article
- [Neurotrophic factors and spinal cord injury. A review]. — PubMed · 1997 · Journal Article
- New view of spinal cord injury. — PubMed · 1996 · Conference Proceedings
- Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat. — PubMed · 1996 · Journal Article
- Prospects for the treatment of spinal cord and peripheral nerve injury. — PubMed · 1996 · Editorial
- Cytoskeletal derangements following central nervous system injury: modulation by neurotrophic gene transfection. — PubMed · 1995 · Journal Article
- Neurotrophic factors in central nervous system trauma. — PubMed · 1995 · Journal Article
- Ex vivo gene therapy for Alzheimer's disease and spinal cord injury. — PubMed · 1995 · Journal Article
- Growth and repair after injury of the central nervous system: yesterday, today and tomorrow. — PubMed · 1994 · Journal Article
- Neurotrophic factor therapy for nervous system degenerative diseases. — PubMed · 1994 · Journal Article
- [Neuronal protection in neurologic diseases?]. — PubMed · 1994 · English Abstract
- Brain repair. — PubMed · 1994 · Journal Article
- Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. — PubMed · 1994 · Journal Article
- Spinal cord injuries. New optimism blooms for developing treatments. — PubMed · 1992 · News
- Polyamines in neurotrauma. Ubiquitous molecules in search of a function. — PubMed · 1992 · Journal Article
- Grafts and growth factors in CNS. Basic science with clinical promise. — PubMed · 1990 · Journal Article
- Cellular mechanisms for recovery from nervous system injury. — PubMed · 1980 · Journal Article
- The possibility of structural and functional restitution after spinal cord injury. A review. — PubMed · 1977 · Case Reports
- The current status of research on growth and regeneration in the central nervous system. Summary of a subcommittee report commissioned by the National Advisory Council of the National Institute of Neurological and Communicative Disorders and Stroke, 1975. — PubMed · 1976 · Journal Article
Indexed as work in animals
- 3D GelMA-Chitosan constructs regulate mesenchymal stem cell fate via YAP-dependent mechanotransduction for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Aligned fibrous scaffolds containing glycosaminoglycan mimetics enhance Schwann cell-supported axon growth and myelination. — PubMed · 2026 · Journal Article
- Impact of hypericin and Hypericum perforatum L. (St. John's Wort) extract on oxidative stress and neurotrophic factors during the acute phase of spinal cord injury in male rats. — PubMed · 2026 · Journal Article
- Inadvertent p75NTR signaling might cause inconsistencies in the neuroprotection offered by mesenchymal stem cells. — PubMed · 2026 · Journal Article
- Hyperbaric oxygen preconditioning alleviates spinal cord injury by inhibiting pro-inflammatory astrocyte polarization in a rat model of decompression sickness. — PubMed · 2026 · Journal Article
- Mo2Ti2C3/CeO2/Neurotrophin-3 MXene Hydrogel Combined with Electrical Stimulation Promotes Functional Recovery by Activating the Biogenesis and Fusion of Mitochondria in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- NINJ1 monoclonal antibody alleviates neuroinflammation and promotes functional recovery after spinal cord injury by suppressing pyroptosis-mediated DAMPs release. — PubMed · 2026 · Journal Article
- Polydopamine-functionalized 3D-printed scaffold co-loaded with resveratrol and NGF for enhanced neuronal differentiation under inflammatory stress. — PubMed · 2026 · Journal Article
- Recombinant Artemin-Fc Fusion Protein Attenuates TLR4/NF-κB-Associated Neuroinflammation and Modulates Inhibitory/Excitatory Synaptic Marker Expression After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Bioactive adipose-derived ECM hydrogel loaded with cytokine-releasing microspheres promotes spinal cord repair by suppressing inflammation, apoptosis, oxidative stress, and ferroptosis. — PubMed · 2026 · Journal Article
- Netrin-1 derived from BMSC-exosomes promotes axonal regeneration and functional recovery after spinal cord injury via inhibition of the RhoA/ROCK pathway. — PubMed · 2026 · Journal Article
- Novel Neurotrophin-3 peptidomimetic synthetic neurotrophin promotes neurological recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Engineered CCR2 positive macrophages coordinate immunoregulation with neural regeneration and matrix remodeling after spinal cord injury. — PubMed · 2026 · Journal Article
- Body weight-supported treadmill training enhances motor recovery and ameliorates neuron injury through the MDK/LRP-1 signaling pathway in T10 incomplete spinal cord-injured rats. — PubMed · 2026 · Journal Article
- Preparation and application of modified peach gum polysaccharide in the repair of central nervous system injury. — PubMed · 2026 · Journal Article
- Netrin-1 Therapy Restores Partial Hindlimb Movement in a Rat Model of High-Severity Chronic Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Temporal Biomarker Profiles Following Non-Surgical Spinal Cord Concussion. — PubMed · 2026 · Journal Article
- Hierarchically functionalized PCL/CS with synergistic PDA-mediated antioxidant therapy and NGF-activated neurogenesis for spinal cord injury regeneration. — PubMed · 2026 · Journal Article
- Role of A-delta low threshold mechanoreceptors and tropomyosin receptor kinase B plasticity in at-level aversive pain after spinal cord injury. — PubMed · 2026 · Journal Article
- Simulated closed-loop magnetic stimulation promotes function recovery and axonal regeneration in spinal cord injury. — PubMed · 2026 · Journal Article
- NanoScript-Enabled Nonviral Transient Repression of Phosphatase and Tensin Homolog for Axonal Regeneration and Central Nervous System Injury Repair. — PubMed · 2026 · Journal Article
- Bone mesenchymal stem cells attenuate axonopathy in spinal cord of rats exposed to 2,5-hexanedione via NGF-dependent and -independent pathways. — PubMed · 2026 · Journal Article
- Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1. — PubMed · 2026 · Journal Article
- Postinjury Carnosine Treatment Prevents Neurotrophic Factor Decline in Denervated Muscle and Spinal Cord After Traumatic Injury. — PubMed · 2026 · Journal Article
- Neuregulin1-ErbB4 Signaling Involved in Acupuncture Promoting Myelin Regeneration in Spinal Cord Injury Rats. — PubMed · 2026 · Journal Article
- Opuntia ficus-indica (L.) Mill. Extract: From Chemical Characterization to Inflammatory Profiling and Its Potential Effects in a Zebrafish Model of Spinal Cord Injury-A Morphological and Molecular Study. — PubMed · 2026 · Journal Article
- Immuno-Neuroprotectants Facilitate Neurological Recovery via Sequestration of Neutrophil Extracellular Traps (NETs) and Promotion of Neuroregeneration. — PubMed · 2026 · Journal Article
- Evaluation of Polyphenol-Rich Lemon Peel Extract Use in a Zebrafish Model of Spinal Cord Injury: Morphology, Repair-Associated Markers, and Inflammatory Profile. — PubMed · 2026 · Journal Article
- Biomimetic core-shell GelMA microspheres co-delivering ANXA1, NGF, and fibronectin enable phase-matched immunomodulation and neurorepair after spinal cord injury. — PubMed · 2026 · Journal Article
- Silencing miR-134-5p promotes functional recovery after spinal cord injury by activating brain-derived neurotrophic factor (BDNF). — PubMed · 2026 · Journal Article
- Spatiotemporal Delivery of Required Facilitators for Microenvironment Remodeling Propels Neural Regeneration after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- The effects of UCN2 on neural cell function of spinal cord injury rats facilitate post-injury neuronal regeneration. — PubMed · 2025 · Journal Article
- POU6F1 promote lumbar motor circuit reorganization following spinal cord injury. — PubMed · 2025 · Journal Article
- Exercise promotes neurological recovery by enhancing neuroplasticity and the spinal cord compensation in stroke-affected rats. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 5 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1558014 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 1726 · this programme has 1726 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])