A subject this map covers
Therapeutic hypothermia
Part of: Neuroprotection
What belongs here
Controlled lowering of body temperature or local cooling of the cord after injury.
What does not belong here, however close it looks
Hypothermia after cardiac arrest or stroke without cord injury does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 266 records · 1958–2026
- Indexed as work in animals: 127 records · 1965–2026
- Indexed as laboratory work: 6 records · 1993–2016
- The source has not said who or what was studied: 105 records · 1975–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
504 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Spinal cord hypothermia. Neurosurgical management of immediate and delayed post-traumatic neurologic sequelae. — PubMed · 1975 · Case Reports
- The problem of gunshot injuries of the spinal cord and cauda equina (report on 10 patients. — PubMed · 1974 · Journal Article
- Spinal cord injury: a review of experimental implications for clinical prognosis and treatment. — PubMed · 1974 · Journal Article
- The pathophysiological response to spinal cord injury. The current status of related research. — PubMed · 1974 · Journal Article
- Emergency treatment of spinal cord injury. — PubMed · 1973 · Journal Article
- Spinal cord hypothermia in the neurosurgical management of the acute and chronic post-traumatic paraplegic patient. — PubMed · 1973 · Journal Article
- Chapter 30. Current status of spinal cord cooling. — PubMed · 1973 · Journal Article
- [Hypothermia of the spinal cord]. — PubMed · 1973 · Journal Article
- Local hypothermia in the treatment of acute injuries of the spinal cord. — PubMed · 1973 · Journal Article
- Recent research on spinal cord injury. — PubMed · 1972 · Journal Article
- Local hypothermia in the treatment of spinal cord injuries. Report of seven cases. — PubMed · 1972 · Journal Article
- Spinal cord complications following surgery for coarctation of the aorta. A study of 66 cases. — PubMed · 1972 · Journal Article
- Acute spinal cord injury: a review of recent studies of treatment and pathophysiology. — PubMed · 1972 · Journal Article
- [Conservative treatment of central nervous system injuries. II. Closed skull injuries: treatment of blood volume and composition disorders, disorders of the aicd-base equilibrium, post-traumatic brain edema. Conservative treatment of spinal cord injury]. — PubMed · 1971 · Journal Article
- Anaesthesia for laminectomy and localized cord cooling in acute cervical spine injury. Report of three cases. — PubMed · 1971 · Journal Article
- Icewater irrigation of the spinal cord. — PubMed · 1971 · Journal Article
- The hypothermostat. An instrument to obtain local hypothermia of the brain or spinal cord. — PubMed · 1970 · Journal Article
- Neurologic surgery. — PubMed · 1970 · Journal Article
- Effects of localized cooling on spinal cord trauma. — PubMed · 1969 · Journal Article
- [Local hypothermia: treatment of paraplegia secondary to spinal cord injuries]. — PubMed · 1969 · Journal Article
- [Therapy of traumatic brain and spinal cord injuries]. — PubMed · 1969 · Journal Article
- CRIPPLING EFFECTS OF DECOMPRESSION SICKNESS: REPORT OF TEN CASES. — PubMed · 1965 · Journal Article
- EXTENSIVE SPINAL EPIDURAL ABSCESS TREATED BY LAMINECTOMY AND HYPOTHERMIA. CASE REPORT. — PubMed · 1964 · Journal Article
- ADVANCES IN NEUROSURGERY. — PubMed · 1963 · Journal Article
- Penetrating wounds of the spinal canal. Problems of paraplegia and notes on autonomic hyperreflexia and sympathetic blockade. — PubMed · 1963 · Journal Article
- [Treatment of autonomic disorders following injuries to the cervical cord]. — PubMed · 1958 · Journal Article
Indexed as work in animals
- Repurposing Dexmedetomidine: Early Pharmacological Hypothermia Enhances Neuroprotection and Improves Locomotor and Bladder Functional Recovery after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Is Cooler Safer and More Advantageous? A Feasibility Study in Rabbits. — PubMed · 2026 · Journal Article
- [Effects of mild hypothermia on neurological function in rats with spinal cord injury based on adenosine monophosphate activated protein kinase/Nod-like receptor protein 3 pathway]. — PubMed · 2025 · English Abstract
- Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia. — PubMed · 2025 · Journal Article
- The potential role of RhoA/ROCK-inhibition on locomotor recovery after spinal cord injury: a systematic review of in-vivo studies. — PubMed · 2025 · Journal Article
- Evaluation of Conditions for the Development of Cryogenic Spinal Cord Injury Using a Canine Model: An Experimental Study on the Safety of Cryoablation for Metastatic Spinal Tumors. — PubMed · 2024 · Journal Article
- Maladaptation of renal hemodynamics contributes to kidney dysfunction resulting from thoracic spinal cord injury in mice. — PubMed · 2022 · Journal Article
- Protective Effect of Mild Hypothermia on Spinal Cord Ischemia-Induced Delayed Paralysis and Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Postcooling But Not Precooling Benefits Motor Recovery by Suppressing Cell Death After Surgical Spinal Cord Injury in Rats. — PubMed · 2022 · Journal Article
- The effect of mild hypothermia plus rutin on the treatment of spinal cord injury and inflammatory factors by repressing TGF-β/smad pathway. — PubMed · 2021 · Journal Article
- Cryogen spray cooling mitigates inflammation and injury-induced CISD2 decline in rat spinal cord hemisection model. — PubMed · 2020 · Journal Article
- Therapeutic hypothermia effectively reduces elevated extracellular ascorbate concentrations caused by acute spinal cord injury. — PubMed · 2019 · Journal Article
- The Effect of Prophylactic Hypothermia on Neurophysiological and Functional Measures in the Setting of Iatrogenic Spinal Cord Impact Injury. — PubMed · 2019 · Journal Article
- Therapeutic hypothermia attenuates paraplegia and neuronal damage in the lumbar spinal cord in a rat model of asphyxial cardiac arrest. — PubMed · 2019 · Journal Article
- Targeted Temperature Management With Total Liquid Ventilation After Ischemic Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Effect of hypothermia on interleukin-1 receptor antagonist pharmacodynamics in inflammatory-sensitized hypoxic-ischemic encephalopathy of term newborns. — PubMed · 2018 · Journal Article
- Neuroprotective assessment of prolonged local hypothermia post contusive spinal cord injury in rodent model. — PubMed · 2018 · Journal Article
- Stretching After Heat But Not After Cold Decreases Contractures After Spinal Cord Injury in Rats. — PubMed · 2016 · Comparative Study
- [The effect of inhibition of hyperplasia on spinal cord reactive astrocytes by mild hypothermia]. — PubMed · 2016 · Journal Article
- Beneficial effects of local profound hypothermia and the possible mechanism after experimental spinal cord injury in rats. — PubMed · 2016 · Journal Article
- A Direct Comparison of Three Clinically Relevant Treatments in a Rat Model of Cervical Spinal Cord Injury. — PubMed · 2015 · Comparative Study
- Autophagy-mediated stress response in motor neurons after hypothermic spinal cord ischemia in rabbits. — PubMed · 2015 · Journal Article
- Prolonged Local Hypothermia Has No Long-Term Adverse Effect on the Spinal Cord. — PubMed · 2015 · Journal Article
- Effects of Therapeutic Hypothermia on Apoptosis and Autophagy After Spinal Cord Injury in Rats. — PubMed · 2015 · Comparative Study
- Effects of hypothermia combined with neural stem cell transplantation on recovery of neurological function in rats with spinal cord injury. — PubMed · 2015 · Journal Article
- [Effect of local hypothermia on H- and M-responses after spinal cord contusion in dogs]. — PubMed · 2014 · English Abstract
- [Protective effect of retrograde venous perfusion of cryogenic liquid via accessory hemiazygos vein and treated with resveratrol on spinal cord injury in swine]. — PubMed · 2013 · Journal Article
- The effect of hypothermia on sensory-motor function and tissue sparing after spinal cord injury. — PubMed · 2013 · Journal Article
- Combined use of an epidural cooling catheter and systemic moderate hypothermia enhances spinal cord protection against ischemic injury in rabbits. — PubMed · 2013 · Journal Article
- A contusion model of severe spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Systematic review and meta-analysis of therapeutic hypothermia in animal models of spinal cord injury. — PubMed · 2013 · Journal Article
- Regional hypothermia inhibits spinal cord somatosensory-evoked potentials without neural damage in uninjured rats. — PubMed · 2013 · Journal Article
- Moderate systemic hypothermia decreases burn depth progression. — PubMed · 2013 · Journal Article
- A simple and effective semi-invasive method for inducing local hypothermia in rat spinal cord. — PubMed · 2013 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-17 | the source found 1388692 · this programme has 47 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 475 · this programme has 475 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("hypothermia" OR "therapeutic cooling") - Crossref
spinal cord injury hypothermia therapeutic cooling - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Hypothermia, Induced"[MeSH Terms] OR "hypothermia"[Title/Abstract] OR "therapeutic cooling"[Title/Abstract])