Напрям, який покриває ця карта

Олігодендроцитарні прогенітори

Що сюди належить

Клітини, призначені дати олігодендроцити й відновити мієлінову оболонку збережених волокон.

Що сюди не належить, хоч і схоже

Ліки, що сприяють ремієлінізації без пересадки клітин, — це нейропротекція або окрема фармакологія.

Що вже дивилися

Порахували з того, як джерела каталогізують роботи, а не з їхнього читання. Це каже, скільки роботи існує і за який проміжок років — і ніколи не каже, що в ній знайшли.

Зареєстровано або проіндексовано як робота з людьми: 288 записів · 1968–2026
Проіндексовано як робота на тваринах: 673 записи · 1964–2026
Проіндексовано як лабораторна робота: 68 записів · 1988–2025
Джерело не сказало, кого або що досліджували: 55 записів · 1998–2024

Перевірено

Записи, які людина прочитала в оригіналі й опублікувала в цій карті. Вони несуть вимірювання, стан доказовості й місце на драбині.

Знайдено у наукових джерелах, ще не перевірено

Назви й ідентифікатори так, як їх публікують джерела. Ніхто тут цих статей не читав, і ніщо на цій полиці не є результатом, рекомендацією чи доказом, що щось працює. Кожен рядок відкриває оригінал.

1084 записи

Це групування — власна каталогізація джерела, а не прочитання статті. Воно каже, куди запис поклали, а не що в ньому знайшли.

мовою оригіналу · англійська

Зареєстровано або проіндексовано як робота з людьми

Decoding TREM2: A microglial receptor governing the fate of myelin. — PubMed · 2026 · Journal Article
Near‑Infrared Photobiomodulation in White‑Matter Disease: From Microglial States to Measurable Endpoints. — PubMed · 2026 · Journal Article
The Hypothesis of Myelinodegeneration as an Initial Risk of Neuropathic Pain. — PubMed · 2026 · Journal Article
Transcutaneous auricular vagus nerve stimulation promotes post-spinal cord injury remyelination via α7nAChR-mediated activation of oligodendrocyte precursor cells. — PubMed · 2026 · Journal Article
Lesion-remote astrocytes govern microglia-mediated white matter repair. — PubMed · 2026 · Journal Article
VEGF-A promotes the proliferation and myelination of induced oligodendrocyte progenitor cells in rat spinal cord injury lesions. — PubMed · 2025 · Journal Article
Roles of Ion Channels in Oligodendrocyte Precursor Cells: From Physiology to Pathology. — PubMed · 2025 · Journal Article
Spinal Cord Injury Remyelination: Pathways to Therapies. — PubMed · 2025 · Journal Article
Morphometric analysis of peripheral nerves in people with spinal cord injury. — PubMed · 2025 · Journal Article
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury — ClinicalTrials.gov · 2025 · Interventional · Recruiting
Quercetin inhibits oligodendrocytes ferroptosis by blocking NCOA4-mediated ferritinophagy. — PubMed · 2025 · Journal Article
Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors. — PubMed · 2025 · Journal Article
Bioinformatics analysis reveals key mechanisms of oligodendrocytes and oligodendrocyte precursor cells regulation in spinal cord Injury. — PubMed · 2025 · Journal Article
Characterizing progenitor cells in developing and injured spinal cord: Insights from single-nucleus transcriptomics and lineage tracing. — PubMed · 2025 · Journal Article
Myelin Imaging of the Spinal Cord in Animal Models and Patients with Multiple Sclerosis Using [(11)C]MeDAS PET: A Translational Study. — PubMed · 2025 · Journal Article
Unraveling the role of oligodendrocytes and myelin in pain. — PubMed · 2025 · Journal Article
Targeting Remyelination in Spinal Cord Injury: Insights and Emerging Therapeutic Strategies. — PubMed · 2024 · Journal Article
A review focuses on a neglected and controversial component of SCI: myelin debris. — PubMed · 2024 · Journal Article
Identification of a New Role of miR-199a-5p as Factor Implied in Neuronal Damage: Decreasing the Expression of Its Target X-Linked Anti-Apoptotic Protein (XIAP) After SCI. — PubMed · 2024 · Journal Article
The roles of neural stem cells in myelin regeneration and repair therapy after spinal cord injury. — PubMed · 2024 · Journal Article
Oligodendrocyte Progenitors in Glial Scar: A Bet on Remyelination. — PubMed · 2024 · Journal Article
Advanced Magnetic Resonance Imaging Biomarkers of the Injured Spinal Cord: A Comparative Study of Imaging and Histology in Human Traumatic Spinal Cord Injury. — PubMed · 2024 · Journal Article
The role of olfactory ensheathing cells in the repair of nerve injury. — PubMed · 2024 · Journal Article
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury. — PubMed · 2024 · Journal Article
Local delivery of AdipoRon from self-assembled microparticles to inhibit myelin lipid uptake and to promote lipid efflux from rat macrophages. — PubMed · 2024 · Journal Article
hBcl2 overexpression in BMSCs enhances resistance to myelin debris-induced apoptosis and facilitates neuroprotection after spinal cord injury in rats. — PubMed · 2024 · Journal Article
Single-cell analysis of spinal cord injury reveals functional heterogeneity of oligodendrocyte lineage cells. — PubMed · 2023 · Journal Article
Quercetin prevents the ferroptosis of OPCs by inhibiting the Id2/transferrin pathway. — PubMed · 2023 · Journal Article
Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injury. — PubMed · 2023 · Journal Article
Mesenchymal Stem Cell Therapy in Traumatic Spinal Cord Injury: A Systematic Review. — PubMed · 2023 · Systematic Review
Amelioration of White Matter Injury Through Mitigating Ferroptosis Following Hepcidin Treatment After Spinal Cord Injury. — PubMed · 2023 · Journal Article
Cell reprogramming for oligodendrocytes: A review of protocols and their applications to disease modeling and cell-based remyelination therapies. — PubMed · 2023 · Journal Article
IPSC-Derived Sensory Neurons Directing Fate Commitment of Human BMSC-Derived Schwann Cells: Applications in Traumatic Neural Injuries. — PubMed · 2023 · Journal Article
Differentiation of Human Induced Pluripotent Stem Cells into Mature and Myelinating Schwann Cells. — PubMed · 2023 · Journal Article
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord. — PubMed · 2023 · Journal Article
Dynamic induction of the myelin-associated growth inhibitor Nogo-A in perilesional plasticity regions after human spinal cord injury. — PubMed · 2023 · Journal Article
Honokiol exerts protective effects on neural myelin sheaths after compressed spinal cord injury by inhibiting oligodendrocyte apoptosis through regulation of ER-mitochondrial interactions. — PubMed · 2022 · Journal Article
D-4F, an apolipoprotein A-I mimetic, promotes the clearance of myelin debris and the reduction of foamy macrophages after spinal cord injury. — PubMed · 2022 · Journal Article
Spinal Cord Injury Inhibits the Differentiation and Maturation of NG2 Cells in the Cerebellum in Mice. — PubMed · 2022 · Journal Article
Chemical approach to generating long-term self-renewing pMN progenitors from human embryonic stem cells. — PubMed · 2022 · Journal Article
A2B5-positive oligodendrocyte precursor cell transplantation improves neurological deficits in rats following spinal cord contusion associated with changes in expression of factors involved in the Notch signaling pathway. — PubMed · 2022 · Journal Article
Taurolithocholic acid but not tauroursodeoxycholic acid rescues phagocytosis activity of bone marrow-derived macrophages under inflammatory stress. — PubMed · 2022 · Journal Article
Protective Effects of Estrogen via Nanoparticle Delivery to Attenuate Myelin Loss and Neuronal Death after Spinal Cord Injury. — PubMed · 2021 · Journal Article
Regenerative replacement of neural cells for treatment of spinal cord injury. — PubMed · 2021 · Journal Article
Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model. — PubMed · 2021 · Journal Article
Human Muse cells-derived neural precursor cells as the novel seed cells for the repair of spinal cord injury. — PubMed · 2021 · Journal Article
Ketogenic diet-mediated steroid metabolism reprogramming improves the immune microenvironment and myelin growth in spinal cord injury rats according to gene and co-expression network analyses. — PubMed · 2021 · Journal Article
The Role of Lipids, Lipid Metabolism and Ectopic Lipid Accumulation in Axon Growth, Regeneration and Repair after CNS Injury and Disease. — PubMed · 2021 · Journal Article
hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats. — PubMed · 2021 · Journal Article
The effects of myelin on macrophage activation are phenotypic specific via cPLA(2) in the context of spinal cord injury inflammation. — PubMed · 2021 · Journal Article
Regionally Specific Human Pre-Oligodendrocyte Progenitor Cells Produce Both Oligodendrocytes and Neurons after Transplantation in a Chronically Injured Spinal Cord Rat Model after Glial Scar Ablation. — PubMed · 2021 · Journal Article
Reactive oligodendrocyte progenitor cells (re-)myelinate the regenerating zebrafish spinal cord. — PubMed · 2020 · Journal Article
Molecular Mechanisms of Central Nervous System Axonal Regeneration and Remyelination: A Review. — PubMed · 2020 · Journal Article
Spatio-temporal and Cellular Expression Patterns of PTK7 in the Healthy and Traumatically Injured Rat and Human Spinal Cord. — PubMed · 2020 · Journal Article
Delayed short-term tamoxifen treatment does not promote remyelination or neuron sparing after spinal cord injury. — PubMed · 2020 · Journal Article
Overexpression of Rictor in the injured spinal cord promotes functional recovery in a rat model of spinal cord injury. — PubMed · 2020 · Journal Article
Treadmill training improves survival and differentiation of transplanted neural precursor cells after cervical spinal cord injury. — PubMed · 2020 · Journal Article
An injectable recombinant human milk fat globule-epidermal growth factor 8-loaded copolymer system for spinal cord injury reduces inflammation through NF-κB and neuronal cell death. — PubMed · 2020 · Journal Article
Prolonged inflammation leads to ongoing damage after spinal cord injury. — PubMed · 2020 · Journal Article
Damage Mechanisms to Oligodendrocytes and White Matter in Central Nervous System Injury: The Australian Context. — PubMed · 2020 · Journal Article

Де це шукали і коли

Точне питання, яке поставили кожному джерелу, день, коли його поставили, і що повернулось. Нуль на цій сторінці чесний лише тоді, коли це на ній є.

ClinicalTrials.gov	запитали, і там нічого немає	запитано 2026-10-05	джерело знайшло 0 · програма отримала 2 · ще очікує 0	мета: усі записи, що відповідають цьому питанню
Crossref	запитали, і воно відповіло	запитано 2026-09-16	джерело знайшло 3677477 · програма отримала 48	мета: вибірка найдоречніших записів. Це джерело ранжує мішок слів, тому його власне число — це розмір корпусу, який має спільні слова, а не борг, який нам ще винні.
PubMed	запитали, і воно відповіло	запитано 2026-09-17	джерело знайшло 1077 · програма отримала 1077 · ще очікує 0	мета: усі записи, що відповідають цьому питанню

Поставлене питання

ClinicalTrials.gov("oligodendrocyte progenitor cell" OR "oligodendrocyte precursor cell" OR "remyelination cell therapy")
Crossrefspinal cord injury oligodendrocyte progenitor cell oligodendrocyte precursor cell
PubMed("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Oligodendroglia"[MeSH Terms] OR "oligodendrocyte progenitor cell"[Title/Abstract] OR "oligodendrocyte precursor cell"[Title/Abstract] OR "remyelination cell therapy"[Title/Abstract])