A subject this map covers
Oligodendrocyte progenitor cells
Part of: Cell therapy
What belongs here
Cells intended to become oligodendrocytes and restore myelin on spared fibres.
What does not belong here, however close it looks
Drugs promoting remyelination without a cell graft are pharmacology, not cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 288 records · 1968–2026
- Indexed as work in animals: 673 records · 1964–2026
- Indexed as laboratory work: 68 records · 1988–2025
- The source has not said who or what was studied: 55 records · 1998–2024
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1084 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Decoding TREM2: A microglial receptor governing the fate of myelin. — PubMed · 2026 · Journal Article
- Near‑Infrared Photobiomodulation in White‑Matter Disease: From Microglial States to Measurable Endpoints. — PubMed · 2026 · Journal Article
- The Hypothesis of Myelinodegeneration as an Initial Risk of Neuropathic Pain. — PubMed · 2026 · Journal Article
- Transcutaneous auricular vagus nerve stimulation promotes post-spinal cord injury remyelination via α7nAChR-mediated activation of oligodendrocyte precursor cells. — PubMed · 2026 · Journal Article
- Lesion-remote astrocytes govern microglia-mediated white matter repair. — PubMed · 2026 · Journal Article
- VEGF-A promotes the proliferation and myelination of induced oligodendrocyte progenitor cells in rat spinal cord injury lesions. — PubMed · 2025 · Journal Article
- Roles of Ion Channels in Oligodendrocyte Precursor Cells: From Physiology to Pathology. — PubMed · 2025 · Journal Article
- Spinal Cord Injury Remyelination: Pathways to Therapies. — PubMed · 2025 · Journal Article
- Morphometric analysis of peripheral nerves in people with spinal cord injury. — PubMed · 2025 · Journal Article
- A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury — ClinicalTrials.gov · 2025 · Interventional · Recruiting
- Quercetin inhibits oligodendrocytes ferroptosis by blocking NCOA4-mediated ferritinophagy. — PubMed · 2025 · Journal Article
- Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors. — PubMed · 2025 · Journal Article
- Bioinformatics analysis reveals key mechanisms of oligodendrocytes and oligodendrocyte precursor cells regulation in spinal cord Injury. — PubMed · 2025 · Journal Article
- Characterizing progenitor cells in developing and injured spinal cord: Insights from single-nucleus transcriptomics and lineage tracing. — PubMed · 2025 · Journal Article
- Myelin Imaging of the Spinal Cord in Animal Models and Patients with Multiple Sclerosis Using [(11)C]MeDAS PET: A Translational Study. — PubMed · 2025 · Journal Article
- Unraveling the role of oligodendrocytes and myelin in pain. — PubMed · 2025 · Journal Article
- Targeting Remyelination in Spinal Cord Injury: Insights and Emerging Therapeutic Strategies. — PubMed · 2024 · Journal Article
- A review focuses on a neglected and controversial component of SCI: myelin debris. — PubMed · 2024 · Journal Article
- Identification of a New Role of miR-199a-5p as Factor Implied in Neuronal Damage: Decreasing the Expression of Its Target X-Linked Anti-Apoptotic Protein (XIAP) After SCI. — PubMed · 2024 · Journal Article
- The roles of neural stem cells in myelin regeneration and repair therapy after spinal cord injury. — PubMed · 2024 · Journal Article
- Oligodendrocyte Progenitors in Glial Scar: A Bet on Remyelination. — PubMed · 2024 · Journal Article
- Advanced Magnetic Resonance Imaging Biomarkers of the Injured Spinal Cord: A Comparative Study of Imaging and Histology in Human Traumatic Spinal Cord Injury. — PubMed · 2024 · Journal Article
- The role of olfactory ensheathing cells in the repair of nerve injury. — PubMed · 2024 · Journal Article
- Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury. — PubMed · 2024 · Journal Article
- Local delivery of AdipoRon from self-assembled microparticles to inhibit myelin lipid uptake and to promote lipid efflux from rat macrophages. — PubMed · 2024 · Journal Article
- hBcl2 overexpression in BMSCs enhances resistance to myelin debris-induced apoptosis and facilitates neuroprotection after spinal cord injury in rats. — PubMed · 2024 · Journal Article
- Single-cell analysis of spinal cord injury reveals functional heterogeneity of oligodendrocyte lineage cells. — PubMed · 2023 · Journal Article
- Quercetin prevents the ferroptosis of OPCs by inhibiting the Id2/transferrin pathway. — PubMed · 2023 · Journal Article
- Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injury. — PubMed · 2023 · Journal Article
- Mesenchymal Stem Cell Therapy in Traumatic Spinal Cord Injury: A Systematic Review. — PubMed · 2023 · Systematic Review
- Amelioration of White Matter Injury Through Mitigating Ferroptosis Following Hepcidin Treatment After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Cell reprogramming for oligodendrocytes: A review of protocols and their applications to disease modeling and cell-based remyelination therapies. — PubMed · 2023 · Journal Article
- IPSC-Derived Sensory Neurons Directing Fate Commitment of Human BMSC-Derived Schwann Cells: Applications in Traumatic Neural Injuries. — PubMed · 2023 · Journal Article
- Differentiation of Human Induced Pluripotent Stem Cells into Mature and Myelinating Schwann Cells. — PubMed · 2023 · Journal Article
- Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord. — PubMed · 2023 · Journal Article
- Dynamic induction of the myelin-associated growth inhibitor Nogo-A in perilesional plasticity regions after human spinal cord injury. — PubMed · 2023 · Journal Article
- Honokiol exerts protective effects on neural myelin sheaths after compressed spinal cord injury by inhibiting oligodendrocyte apoptosis through regulation of ER-mitochondrial interactions. — PubMed · 2022 · Journal Article
- D-4F, an apolipoprotein A-I mimetic, promotes the clearance of myelin debris and the reduction of foamy macrophages after spinal cord injury. — PubMed · 2022 · Journal Article
- Spinal Cord Injury Inhibits the Differentiation and Maturation of NG2 Cells in the Cerebellum in Mice. — PubMed · 2022 · Journal Article
- Chemical approach to generating long-term self-renewing pMN progenitors from human embryonic stem cells. — PubMed · 2022 · Journal Article
- A2B5-positive oligodendrocyte precursor cell transplantation improves neurological deficits in rats following spinal cord contusion associated with changes in expression of factors involved in the Notch signaling pathway. — PubMed · 2022 · Journal Article
- Taurolithocholic acid but not tauroursodeoxycholic acid rescues phagocytosis activity of bone marrow-derived macrophages under inflammatory stress. — PubMed · 2022 · Journal Article
- Protective Effects of Estrogen via Nanoparticle Delivery to Attenuate Myelin Loss and Neuronal Death after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Regenerative replacement of neural cells for treatment of spinal cord injury. — PubMed · 2021 · Journal Article
- Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model. — PubMed · 2021 · Journal Article
- Human Muse cells-derived neural precursor cells as the novel seed cells for the repair of spinal cord injury. — PubMed · 2021 · Journal Article
- Ketogenic diet-mediated steroid metabolism reprogramming improves the immune microenvironment and myelin growth in spinal cord injury rats according to gene and co-expression network analyses. — PubMed · 2021 · Journal Article
- The Role of Lipids, Lipid Metabolism and Ectopic Lipid Accumulation in Axon Growth, Regeneration and Repair after CNS Injury and Disease. — PubMed · 2021 · Journal Article
- hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats. — PubMed · 2021 · Journal Article
- The effects of myelin on macrophage activation are phenotypic specific via cPLA(2) in the context of spinal cord injury inflammation. — PubMed · 2021 · Journal Article
- Regionally Specific Human Pre-Oligodendrocyte Progenitor Cells Produce Both Oligodendrocytes and Neurons after Transplantation in a Chronically Injured Spinal Cord Rat Model after Glial Scar Ablation. — PubMed · 2021 · Journal Article
- Reactive oligodendrocyte progenitor cells (re-)myelinate the regenerating zebrafish spinal cord. — PubMed · 2020 · Journal Article
- Molecular Mechanisms of Central Nervous System Axonal Regeneration and Remyelination: A Review. — PubMed · 2020 · Journal Article
- Spatio-temporal and Cellular Expression Patterns of PTK7 in the Healthy and Traumatically Injured Rat and Human Spinal Cord. — PubMed · 2020 · Journal Article
- Delayed short-term tamoxifen treatment does not promote remyelination or neuron sparing after spinal cord injury. — PubMed · 2020 · Journal Article
- Overexpression of Rictor in the injured spinal cord promotes functional recovery in a rat model of spinal cord injury. — PubMed · 2020 · Journal Article
- Treadmill training improves survival and differentiation of transplanted neural precursor cells after cervical spinal cord injury. — PubMed · 2020 · Journal Article
- An injectable recombinant human milk fat globule-epidermal growth factor 8-loaded copolymer system for spinal cord injury reduces inflammation through NF-κB and neuronal cell death. — PubMed · 2020 · Journal Article
- Prolonged inflammation leads to ongoing damage after spinal cord injury. — PubMed · 2020 · Journal Article
- Damage Mechanisms to Oligodendrocytes and White Matter in Central Nervous System Injury: The Australian Context. — PubMed · 2020 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 3677477 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 1077 · this programme has 1077 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("oligodendrocyte progenitor cell" OR "oligodendrocyte precursor cell" OR "remyelination cell therapy") - Crossref
spinal cord injury oligodendrocyte progenitor cell oligodendrocyte precursor cell - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Oligodendroglia"[MeSH Terms] OR "oligodendrocyte progenitor cell"[Title/Abstract] OR "oligodendrocyte precursor cell"[Title/Abstract] OR "remyelination cell therapy"[Title/Abstract])