A subject this map covers
Extracellular vesicles and exosomes
Part of: Cell therapy
What belongs here
Products of cells without the cells: vesicles, exosomes, conditioned medium, delivered in spinal cord injury.
What does not belong here, however close it looks
Delivering living cells, even when the authors credit their vesicles, is cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 226 records · 2000–2026
- Indexed as work in animals: 224 records · 1998–2026
- Indexed as laboratory work: 33 records · 2003–2026
- The source has not said who or what was studied: 171 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
654 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- MSC derived EV loaded with miRNA-22 inhibits the inflammatory response and nerve function recovery after spinal cord injury in rats. — PubMed · 2021 · Journal Article
- Efficacy of dental pulp-derived stem cells conditioned medium loaded in collagen hydrogel in spinal cord injury in rats: Stereological evidence. — PubMed · 2021 · Journal Article
- Rat Bone Mesenchymal Stem Cell-Derived Exosomes Loaded with miR-494 Promoting Neurofilament Regeneration and Behavioral Function Recovery after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats. — PubMed · 2021 · Journal Article
- Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF-β upregulation, microvascular stabilization and functional recovery in a rodent model of severe spinal cord injury. — PubMed · 2021 · Journal Article
- Increasing toll-like receptor 2 on astrocytes induced by Schwann cell-derived exosomes promotes recovery by inhibiting CSPGs deposition after spinal cord injury. — PubMed · 2021 · Journal Article
- Exosomes secreted from sonic hedgehog-modified bone mesenchymal stem cells facilitate the repair of rat spinal cord injuries. — PubMed · 2021 · Journal Article
- The Conditioned Medium of Lactobacillus rhamnoides GG Regulates Microglia/Macrophage Polarization and Improves Functional Recovery after Spinal Cord Injury in Rats. — PubMed · 2021 · Journal Article The source marks this record as retracted.
- SiRNA in MSC-derived exosomes silences CTGF gene for locomotor recovery in spinal cord injury rats. — PubMed · 2021 · Journal Article
- Extracellular Vesicles as an Emerging Frontier in Spinal Cord Injury Pathobiology and Therapy. — PubMed · 2021 · Journal Article
- Photobiomodulation Promotes Neuronal Axon Regeneration After Oxidative Stress and Induces a Change in Polarization from M1 to M2 in Macrophages via Stimulation of CCL2 in Neurons: Relevance to Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Uptake of Fluorescent Labeled Small Extracellular Vesicles In Vitro and in Spinal Cord. — PubMed · 2021 · Journal Article
- Berberine-loaded M2 macrophage-derived exosomes for spinal cord injury therapy. — PubMed · 2021 · Journal Article
- Bone marrow mesenchymal stem cell-derived exosomal microRNA-125a promotes M2 macrophage polarization in spinal cord injury by downregulating IRF5. — PubMed · 2021 · Journal Article
- Mesenchymal stem cell-derived exosomes containing miR-145-5p reduce inflammation in spinal cord injury by regulating the TLR4/NF-κB signaling pathway. — PubMed · 2021 · Journal Article
- [Experimental study of endothelial progenitor cells derived small extracellular vesicles for spinal cord injury repair in mice]. — PubMed · 2021 · Journal Article
- Exosomes derived from miR-26a-modified MSCs promote axonal regeneration via the PTEN/AKT/mTOR pathway following spinal cord injury. — PubMed · 2021 · Journal Article
- Exosomes with high level of miR-181c from bone marrow-derived mesenchymal stem cells inhibit inflammation and apoptosis to alleviate spinal cord injury. — PubMed · 2021 · Journal Article
- NSCs Migration Promoted and Drug Delivered Exosomes-Collagen Scaffold via a Bio-Specific Peptide for One-Step Spinal Cord Injury Repair. — PubMed · 2021 · Journal Article
- Peripheral Macrophage-derived Exosomes promote repair after Spinal Cord Injury by inducing Local Anti-inflammatory type Microglial Polarization via Increasing Autophagy. — PubMed · 2021 · Journal Article
- Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p/145-5p-mediated NGF/TrkA signaling pathway in rats. — PubMed · 2021 · Journal Article
- Exosomes derived from GIT1-overexpressing bone marrow mesenchymal stem cells promote traumatic spinal cord injury recovery in a rat model. — PubMed · 2021 · Journal Article
- Spinal cord injury alters microRNA and CD81+ exosome levels in plasma extracellular nanoparticles with neuroinflammatory potential. — PubMed · 2021 · Journal Article
- Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/β1 integrin pathway. — PubMed · 2021 · Journal Article
- Serum exosomal microRNA transcriptome profiling in subacute spinal cord injured rats. — PubMed · 2020 · Journal Article
- Exosomes derived from miR-544-modified mesenchymal stem cells promote recovery after spinal cord injury. — PubMed · 2020 · Journal Article
- Resveratrol-primed exosomes strongly promote the recovery of motor function in SCI rats by activating autophagy and inhibiting apoptosis via the PI3K signaling pathway. — PubMed · 2020 · Journal Article
- Exosomes from Long Noncoding RNA-Gm37494-ADSCs Repair Spinal Cord Injury via Shifting Microglial M1/M2 Polarization. — PubMed · 2020 · Journal Article
- Reactive astrocytes increase expression of proNGF in the mouse model of contused spinal cord injury. — PubMed · 2020 · Journal Article
- Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes. — PubMed · 2020 · Journal Article
- Stem Cell Conditioned Medium Treatment for Canine Spinal Cord Injury: Pilot Feasibility Study. — PubMed · 2020 · Journal Article
- Subventricular zone-derived extracellular vesicles promote functional recovery in rat model of spinal cord injury by inhibition of NLRP3 inflammasome complex formation. — PubMed · 2020 · Journal Article
- The role of hepatocyte growth factor in mesenchymal stem cell-induced recovery in spinal cord injured rats. — PubMed · 2020 · Journal Article
- MicroRNA-421-3p-abundant small extracellular vesicles derived from M2 bone marrow-derived macrophages attenuate apoptosis and promote motor function recovery via inhibition of mTOR in spinal cord injury. — PubMed · 2020 · Journal Article
- Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Improves Spinal Cord Function After Injury in Rats by Activating Autophagy. — PubMed · 2020 · Journal Article
- Bone marrow mesenchymal stem cell-derived exosomal microRNA-124-3p attenuates neurological damage in spinal cord ischemia-reperfusion injury by downregulating Ern1 and promoting M2 macrophage polarization. — PubMed · 2020 · Journal Article
- Modulating Pro-inflammatory Cytokines, Tissue Damage Magnitude, and Motor Deficit in Spinal Cord Injury with Subventricular Zone-Derived Extracellular Vesicles. — PubMed · 2020 · Journal Article
- Serum exosomal microRNA transcriptome profiling in subacute spinal cord injured rats. — PubMed · 2020 · Journal Article
- Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury. — PubMed · 2020 · Journal Article
- Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization. — PubMed · 2020 · Journal Article
- Neural stem cell-derived exosomes facilitate spinal cord functional recovery after injury by promoting angiogenesis. — PubMed · 2020 · Journal Article
- Insulin-like growth factor-1 enhances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism. — PubMed · 2019 · Journal Article
- Exosomes secreted from miRNA-29b-modified mesenchymal stem cells repaired spinal cord injury in rats. — PubMed · 2019 · Journal Article
- miR-21 deficiency contributes to the impaired protective effects of obese rat mesenchymal stem cell-derived exosomes against spinal cord injury. — PubMed · 2019 · Journal Article
- Bone mesenchymal stem cell-conditioned medium attenuates the effect of oxidative stress injury on NSCs by inhibiting the Notch1 signaling pathway. — PubMed · 2019 · Journal Article
- Exosomes from Bone Marrow Mesenchymal Stem Cells Inhibit Neuronal Apoptosis and Promote Motor Function Recovery via the Wnt/β-catenin Signaling Pathway. — PubMed · 2019 · Journal Article
- Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Identification of serum exosomal microRNAs in acute spinal cord injured rats. — PubMed · 2019 · Journal Article
- Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1. — PubMed · 2019 · Journal Article
- Canine Bone Marrow-derived Mesenchymal Stem Cells: Genomics, Proteomics and Functional Analyses of Paracrine Factors. — PubMed · 2019 · Journal Article
- Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis. — PubMed · 2019 · Journal Article
- Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy. — PubMed · 2019 · Journal Article
- Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells. — PubMed · 2019 · Journal Article
- Release of astroglial vimentin by extracellular vesicles: Modulation of binding and internalization of C3 transferase in astrocytes and neurons. — PubMed · 2019 · Journal Article
- Hypoxia preconditioning promotes bone marrow mesenchymal stem cells survival by inducing HIF-1α in injured neuronal cells derived exosomes culture system. — PubMed · 2019 · Journal Article
- Exosomes Derived from Bone Mesenchymal Stem Cells Repair Traumatic Spinal Cord Injury by Suppressing the Activation of A1 Neurotoxic Reactive Astrocytes. — PubMed · 2019 · Journal Article
- Localized Intrathecal Delivery of Mesenchymal Stromal Cells Conditioned Medium Improves Functional Recovery in a Rat Model of Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons. — PubMed · 2018 · Journal Article
- Effects of Intrathecal Injection of the Conditioned Medium from Bone Marrow Stromal Cells on Spinal Cord Injury in Rats. — PubMed · 2018 · Journal Article
- The role of exosomes derived from cerebrospinal fluid of spinal cord injury in neuron proliferation in vitro. — PubMed · 2018 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 963561 · this programme has 49 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 12 · this programme has 639 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("extracellular vesicle" OR "exosome" OR "conditioned medium" OR "secretome") - Crossref
spinal cord injury extracellular vesicle exosome - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Extracellular Vesicles"[MeSH Terms] OR "Exosomes"[MeSH Terms] OR "extracellular vesicle"[Title/Abstract] OR "exosome"[Title/Abstract] OR "conditioned medium"[Title/Abstract] OR "secretome"[Title/Abstract])