A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Mesenchymal stem cell-derived small extracellular vesicles in spinal cord injury: From molecular repair mechanisms to standardized translational development. — PubMed · 2026 · Journal Article
- Soft substrate priming erases fibrotic mechanical memory in mesenchymal stromal cells via YAP lysosomal degradation to improve therapeutic efficacy for spinal cord injury. — PubMed · 2026 · Journal Article
- Paclitaxel-induced astrocytic immunogenic cell death promotes motor function recovery in mice with spinal cord injury. — PubMed · 2026 · Journal Article
- Mechanisms of Serotonergic Modulation of Glial Cell Functions in the Recovery Period After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- A four-dimensional spatial atlas of spinal cord injury reveals predominant Spp1-integrin signaling driving microglia-fibroblast crosstalk in fibrotic niches. — PubMed · 2026 · Journal Article
- Multi-time-point controlled-release methylprednisolone composite scaffolds based on clinical benchmarking for promoting spinal cord injury repair. — PubMed · 2026 · Journal Article
- Advances in ferroptosis and cuproptosis: implications for spinal cord injury. — PubMed · 2026 · Journal Article
- Beyond Scar Removal: Reprogramming the Glial Scar for Neural Repair. — PubMed · 2026 · Journal Article
- Notch Signaling in Spinal Cord Injury: Mechanistic Insights and Therapeutic Perspectives. — PubMed · 2026 · Journal Article
- From neural stem cells to cell-free exosome nanotherapy: reprogramming the injured spinal cord microenvironment for regeneration. — PubMed · 2026 · Journal Article
- Harnessing wireless electrical stimulation and silk-based conductive hydrogels to boost iPSC-derived astrocytes neuroprotection and guide macrophage polarisation in vitro for spinal cord repair. — PubMed · 2026 · Journal Article
- Overcoming Barriers to Axonal Regeneration in Spinal Cord Injury: Mechanistic Insights and Therapeutic Frontiers. — PubMed · 2026 · Journal Article
- Platelet lysate derived macroporous hydrogel loaded with adipose stem cells for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Risk factors for renal scarring in individuals with spinal cord injury: A retrospective study. — PubMed · 2026 · Journal Article
- Understanding the Role of Fibrotic Scarring in Shaping the Lesion Site and Neural Repair After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Repurposing tumor-derived extracellular vesicles with an adhesive carboxymethyl chitosan-based hydrogel for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Multimodal Treatment of Chronic Spinal Cord Injury With Human Cord Blood Stem Cell Therapy, Surgery, and Regenerative Rehabilitation: Clinical Review. — PubMed · 2026 · Journal Article
- Orchestrating Scarless Spinal Cord Repair: Dynamic Glial-Immune Interplay and Biomaterial Support. — PubMed · 2026 · Journal Article
- A novel Minimally-Invasive technique for Non-Traumatic postoperative adhesive Syringomyelia. — PubMed · 2026 · Journal Article
- Reprogramming the Inflammatory Response to Promote Neural Stem Cell Function After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Research Progress on Spinal Cord Repair Based on Regulation of the Neuroregenerative Microenvironment. — PubMed · 2026 · Journal Article
- Activated Platelet-Rich Plasma Fibrin Scaffolds Enhance Axonal Regeneration and Functional Recovery Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Efficient generation of human dorsal spinal GABAergic progenitors for the treatment of spinal cord injury. — PubMed · 2026 · Journal Article
- Systemic Interleukin-4 Application Promotes Functional Recovery and Reprograms Neuroinflammatory and Molecular Responses after Spinal Cord Injury in Rats. — PubMed · 2026 · Journal Article
- Recent Advances in Hydrogels as Therapeutic Tools for Spinal Cord Injury Regeneration. — PubMed · 2026 · Journal Article
- Nanomaterial-based therapeutic strategies for spinal cord injury repair: harnessing multifunctionality to overcome pathophysiological challenges. — PubMed · 2026 · Journal Article
- Metformin in Preventing Secondary Gliosis Following Acute Thoraco-Lumbar Spinal Cord Injury — ClinicalTrials.gov · 2026 · Interventional · Not Yet Recruiting
- Repurposing of Chemokine Antagonists for Combined Phase-Resolved Spinal Cord Injury Treatment. — PubMed · 2026 · Journal Article
- Spinal segment-specific properties of neural stem cells contribute to the outcomes of spinal cord injury repair. — PubMed · 2026 · Journal Article
- Mesenchymal Stem Cell-Derived Exosomes: A Promising Therapeutic Strategy for Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Mechanism analysis and intervention strategies of the inflammatory microenvironment in traumatic spinal cord injury. — PubMed · 2025 · Journal Article
- Neurovascular dynamics in the spinal cord from development to pathophysiology. — PubMed · 2025 · Journal Article
- The role of polarization dynamics in macrophages and microglia on the inflammatory microenvironment of spinal cord injury. — PubMed · 2025 · Journal Article
- Letter to the Editor Rebuttal to Qi et al. (2025): "Alpha 9 integrin in spinal cord repair: a critical appraisal of mechanisms, circuitry, and translational potential". — PubMed · 2025 · Letter
- Application and challenge of Schwann cell transplantation in spinal cord injury and clinical trial. — PubMed · 2025 · Journal Article
- Calcium Signaling in Astrocytes and Its Role in the Central Nervous System Injury. — PubMed · 2025 · Journal Article
- ZEB2: a multifunctional regulator of neural injury repair. — PubMed · 2025 · Journal Article
- Immune Activation Following Spinal Cord Injury: A Review Focused on Inflammatory Changes in the Spinal Cord. — PubMed · 2025 · Journal Article
- GelMA Hydrogel Encapsulating iPSC-Derived Human Spinal Cord Organoids Enhances Neural Regeneration and Restores Motor Function in Rat Spinal Cord Injury. — PubMed · 2025 · Journal Article
- The neuroinflammatory triumvirate: NF-κB, NLRP3, and mTOR in spinal cord injury. — PubMed · 2025 · Journal Article
- CRISPR and Artificial Intelligence in Neuroregeneration: Closed-Loop Strategies for Precision Medicine, Spinal Cord Repair, and Adaptive Neuro-Oncology. — PubMed · 2025 · Journal Article
- How Advanced Are Exosomes as Cell-Free Therapeutics for Spinal Cord Injury? — PubMed · 2025 · Journal Article
- Astrocytic monoamine oxidase B (MAOB)-gamma-aminobutyric acid (GABA) axis as a molecular brake on repair following spinal cord injury. — PubMed · 2025 · Journal Article
- F-box/LRR-repeat protein 12 reorchestrated microglia to inhibit scarring and achieve adult spinal cord injury repair. — PubMed · 2025 · Journal Article
- Evolving insights on the role of microglia in neuroinflammation, plasticity, and regeneration of the injured spinal cord. — PubMed · 2025 · Journal Article
- Advanced Therapeutic Approaches Based on Small Extracellular Vehicles (sEVs) For the Regeneration of Spinal Cord Injuries. — PubMed · 2025 · Journal Article
- Autophagy modulation by hADSCs and green light therapy alleviates inflammation and promotes functional recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- Astrocytic Ryk signaling coordinates scarring and wound healing after spinal cord injury. — PubMed · 2025 · Journal Article
- [Electroacupuncture of "Jiaji" (EX-B2) inhibits neuroinflammatory response and glial scar formation by regulating the expression of neutrophil extracellular traps in mice with spinal cord injury]. — PubMed · 2025 · Journal Article
- Astrocytic heterogeneous nuclear ribonucleoprotein U is involved in scar formation after spinal cord injury. — PubMed · 2025 · Journal Article
- Neurons Are Not All the Same: Diversity in Neuronal Populations and Their Intrinsic Responses to Spinal Cord Injury. — PubMed · 2025 · Journal Article
- The Glial Scar: To Penetrate or Not for Motor Pathway Restoration? — PubMed · 2025 · Journal Article
- Thoracic spinal cord compression due to excessive scarring around surgical paddle epidural electrodes. Report of two cases with literature review. — PubMed · 2025 · Journal Article
- Histological effects of combined therapy involving scar resection, decellularized scaffolds, and human iPSC-NS/PCs transplantation in chronic complete spinal cord injury. — PubMed · 2024 · Journal Article
- Therapeutic potential of placenta-derived stem cells cultivated on noggin-loaded nanochitosan/polypyrrole-alginate conductive scaffold to restore spinal cord injury. — PubMed · 2024 · Journal Article
- Cell Sheets Formation Enhances Therapeutic Effects of Human Umbilical Cord Mesenchymal Stem Cells on Spinal Cord Injury. — PubMed · 2024 · Journal Article
- FGF20 promotes spinal cord injury repair by inhibiting the formation of necrotic corpuscle P-MLKL/P-RIP1/P-RIP3 in neurons. — PubMed · 2024 · Journal Article
- Bibliometric analysis of the inflammation expression after spinal cord injury: current research status and emerging frontiers. — PubMed · 2024 · Journal Article
- From apoptosis to pyroptosis: A two-decade analysis of spinal cord injury systematic review. — PubMed · 2024 · Journal Article
- Unravelling the Road to Recovery: Mechanisms of Wnt Signalling in Spinal Cord Injury. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])