A subject this map covers
Scar proteoglycan modulation
Part of: Glial scar and its remodelling
What belongs here
Acting on the scar’s inhibitory molecules or their receptors without enzymatic digestion.
What does not belong here, however close it looks
Enzymatic digestion is chondroitinase, a separate concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 84 records · 2000–2025
- Indexed as work in animals: 244 records · 1997–2026
- Indexed as laboratory work: 23 records · 2004–2021
- The source has not said who or what was studied: 68 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
419 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Integration of angiogenesis and programmed cell death mechanisms unveils potential diagnostic and therapeutic targets in spinal cord injury. — PubMed · 2025 · Journal Article
- Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain. — PubMed · 2025 · Journal Article
- Systematic Review of Peptide CAQK: Properties, Applications, and Outcomes. — PubMed · 2024 · Journal Article
- Remodeling Microenvironment for Endogenous Repair through Precise Modulation of Chondroitin Sulfate Proteoglycans Following Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Glial scar survives until the chronic phase by recruiting scar-forming astrocytes after spinal cord injury. — PubMed · 2023 · Journal Article
- More Attention on Segments Remote from the Primary Spinal Cord Lesion Site. — PubMed · 2022 · Journal Article
- Advances in chondroitinase delivery for spinal cord repair. — PubMed · 2022 · Journal Article
- Dual-functional hydrogel system for spinal cord regeneration with sustained release of arylsulfatase B alleviates fibrotic microenvironment and promotes axonal regeneration. — PubMed · 2022 · Journal Article
- Suppressing CSPG/LAR/PTPσ Axis Facilitates Neuronal Replacement and Synaptogenesis by Human Neural Precursor Grafts and Improves Recovery after Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Small Molecules Targeting PTPσ-Trk Interactions Promote Sympathetic Nerve Regeneration. — PubMed · 2022 · Journal Article
- Multiple therapeutic effects of human neural stem cells derived from induced pluripotent stem cells in a rat model of post-traumatic syringomyelia. — PubMed · 2022 · Journal Article
- Diversity of Adult Neural Stem and Progenitor Cells in Physiology and Disease. — PubMed · 2021 · Journal Article
- Inhibition of Chondroitin Sulfate Proteoglycans by APRIL. — PubMed · 2021 · Journal Article
- Multi-target approaches to CNS repair: olfactory mucosa-derived cells and heparan sulfates. — PubMed · 2020 · Journal Article
- Epac2 Promotes Axonal Outgrowth and Attenuates the Glial Reaction in an Ex Vivo Model of Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Enhancing myelin repair in experimental model of multiple sclerosis using immobilized chondroitinase ABC I on porous silicon nanoparticles. — PubMed · 2020 · Journal Article
- Targeting Chondroitin Sulfate Proteoglycans: An Emerging Therapeutic Strategy to Treat CNS Injury. — PubMed · 2020 · Journal Article
- Diltiazem Promotes Regenerative Axon Growth. — PubMed · 2019 · Journal Article
- Time is spine: a review of translational advances in spinal cord injury. — PubMed · 2018 · Journal Article
- Human Oligodendrogenic Neural Progenitor Cells Delivered with Chondroitinase ABC Facilitate Functional Repair of Chronic Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Pro-inflammatory roles of chondroitin sulfate proteoglycans in disorders of the central nervous system. — PubMed · 2018 · Journal Article
- Roles of CSGalNAcT1, a key enzyme in regulation of CS synthesis, in neuronal regeneration and plasticity. — PubMed · 2018 · Journal Article
- Adult rat myelin enhances axonal outgrowth from neural stem cells. — PubMed · 2018 · Journal Article
- Dissecting spinal cord regeneration. — PubMed · 2018 · Journal Article
- The Biology of Regeneration Failure and Success After Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Chondrotinase ABC I thermal stability is enhanced by site-directed mutagenesis: a molecular dynamic simulations approach. — PubMed · 2018 · Journal Article
- Cetuximab modified collagen scaffold directs neurogenesis of injury-activated endogenous neural stem cells for acute spinal cord injury repair. — PubMed · 2017 · Journal Article
- Lentiviral Delivery of miR-133b Improves Functional Recovery After Spinal Cord Injury in Mice. — PubMed · 2017 · Journal Article
- Rapid generation of OPC-like cells from human pluripotent stem cells for treating spinal cord injury. — PubMed · 2017 · Journal Article
- Post-spinal cord injury astrocyte-mediated functional recovery in rats after intraspinal injection of the recombinant adenoviral vectors Ad5-VEGF and Ad5-ANG. — PubMed · 2017 · Journal Article
- Combined chondroitinase and KLF7 expression reduce net retraction of sensory and CST axons from sites of spinal injury. — PubMed · 2017 · Journal Article
- Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity. — PubMed · 2016 · Journal Article
- Conditional Sox9 ablation improves locomotor recovery after spinal cord injury by increasing reactive sprouting. — PubMed · 2016 · Journal Article
- Nucleolin inhibitor GroA triggers reduction in epidermal growth factor receptor activation: Pharmacological implication for glial scarring after spinal cord injury. — PubMed · 2016 · Journal Article
- Canine olfactory ensheathing cells from the olfactory mucosa can be engineered to produce active chondroitinase ABC. — PubMed · 2016 · Journal Article
- Concise Review: Bridging the Gap: Novel Neuroregenerative and Neuroprotective Strategies in Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Diffusion tensor imaging with direct cytopathological validation: characterisation of decorin treatment in experimental juvenile communicating hydrocephalus. — PubMed · 2016 · Journal Article
- Chondroitinase: A promising therapeutic enzyme. — PubMed · 2016 · Journal Article
- The reactions and role of NG2 glia in spinal cord injury. — PubMed · 2016 · Journal Article
- The role of the PI3K/Akt/mTOR pathway in glial scar formation following spinal cord injury. — PubMed · 2016 · Journal Article
- Graft of the NT-3 persistent delivery gelatin sponge scaffold promotes axon regeneration, attenuates inflammation, and induces cell migration in rat and canine with spinal cord injury. — PubMed · 2016 · Journal Article
- "Inhibiting the Inhibitors" to Support Axonal Regeneration. — PubMed · 2016 · Journal Article
- Molecular mechanisms of scar-sourced axon growth inhibitors. — PubMed · 2015 · Journal Article
- Phenotypic assays to identify agents that induce reactive gliosis: a counter-screen to prioritize compounds for preclinical animal studies. — PubMed · 2015 · Journal Article
- Chondroitin sulfate proteoglycans: Key modulators in the developing and pathologic central nervous system. — PubMed · 2015 · Journal Article
- ADAMTS expression and function in central nervous system injury and disorders. — PubMed · 2015 · Journal Article
- NG2+ progenitors derived from embryonic stem cells penetrate glial scar and promote axonal outgrowth into white matter after spinal cord injury. — PubMed · 2015 · Journal Article
- Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury. — PubMed · 2015 · Journal Article
- Neuroprotective Effect of Simvastatin via Inducing the Autophagy on Spinal Cord Injury in the Rat Model. — PubMed · 2015 · Journal Article
- The extracellular matrix in plasticity and regeneration after CNS injury and neurodegenerative disease. — PubMed · 2015 · Journal Article
- Perineuronal net, CSPG receptor and their regulation of neural plasticity. — PubMed · 2014 · Journal Article
- Decorin blocks scarring and cystic cavitation in acute and induces scar dissolution in chronic spinal cord wounds. — PubMed · 2014 · Journal Article
- Third trimester NG2-positive amniotic fluid cells are effective in improving repair in spinal cord injury. — PubMed · 2014 · Journal Article
- ADAMTS4 and ADAMTS5 knockout mice are protected from versican but not aggrecan or brevican proteolysis during spinal cord injury. — PubMed · 2014 · Journal Article
- Targeting the neural extracellular matrix in neurological disorders. — PubMed · 2013 · Journal Article
- Pathophysiology of the brain extracellular matrix: a new target for remyelination. — PubMed · 2013 · Journal Article
- Where no synapses go: gatekeepers of circuit remodeling and synaptic strength. — PubMed · 2013 · Journal Article
- Differentiation of oligodendrocyte progenitor cells from human embryonic stem cells on vitronectin-derived synthetic peptide acrylate surface. — PubMed · 2013 · Journal Article
- Scar-mediated inhibition and CSPG receptors in the CNS. — PubMed · 2012 · Journal Article
- Dependence of regenerated sensory axons on continuous neurotrophin-3 delivery. — PubMed · 2012 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1527414 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 404 · this programme has 404 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("chondroitin sulfate proteoglycan" OR "CSPG receptor" OR "PTPsigma peptide") - Crossref
spinal cord injury chondroitin sulfate proteoglycan CSPG receptor - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Chondroitin Sulfate Proteoglycans"[MeSH Terms] OR "chondroitin sulfate proteoglycan"[Title/Abstract] OR "CSPG receptor"[Title/Abstract] OR "PTPsigma peptide"[Title/Abstract])