A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
The source has not said who or what was studied
- Novel therapeutic approach to slow down the inflammatory cascade in acute/subacute spinal cord injury: Early immune therapy with lipopolysaccharide enhanced neuroprotective effect of combinational therapy of granulocyte colony-stimulating factor and bone-marrow mesenchymal stem cell in spinal cord injury. — PubMed · 2022 · Journal Article
- Quercetin Derivatives in Combating Spinal Cord Injury: A Mechanistic and Systematic Review. — PubMed · 2022 · Journal Article
- Sustained release of hydrogen sulfide from anisotropic ferrofluid hydrogel for the repair of spinal cord injury. — PubMed · 2022 · Journal Article
- Intestinal microbiota and melatonin in the treatment of secondary injury and complications after spinal cord injury. — PubMed · 2022 · Journal Article
- Endogenous reparative pluripotent Muse cells with a unique immune privilege system: Hint at a new strategy for controlling acute and chronic inflammation. — PubMed · 2022 · Journal Article
- The therapeutic potential of triptolide and celastrol in neurological diseases. — PubMed · 2022 · Journal Article
- Application of natural antioxidants from traditional Chinese medicine in the treatment of spinal cord injury. — PubMed · 2022 · Journal Article
- Photobiomodulation for the treatment of neuroinflammation: A systematic review of controlled laboratory animal studies. — PubMed · 2022 · Systematic Review
- Protective role of ethyl pyruvate in spinal cord injury by inhibiting the high mobility group box-1/toll-like receptor4/nuclear factor-kappa B signaling pathway. — PubMed · 2022 · Journal Article
- Therapy of spinal cord injury by folic acid polyethylene glycol amine-modified zeolitic imidazole framework-8 nanoparticles targeted activated M/Ms. — PubMed · 2022 · Journal Article
- Epigallocatechin-3-gallate selenium nanoparticles for neuroprotection by scavenging reactive oxygen species and reducing inflammation. — PubMed · 2022 · Journal Article
- Protective role of muscones on astrocytes under a mechanical-chemical damage model. — PubMed · 2022 · Journal Article
- Pharmacological and non-pharmacological therapeutic interventions for the treatment of spinal cord injury-induced pain. — PubMed · 2022 · Journal Article
- Effectiveness of Prophylactic Interventions in Neurogenic Heterotopic Ossification (NHO): A Systematic Review. — PubMed · 2022 · Journal Article
- Neuroprotective Mechanisms of Puerarin in Central Nervous System Diseases: Update. — PubMed · 2022 · Journal Article
- Immunomodulatory Strategies for Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Intrathecal administration of naringenin improves motor dysfunction and neuropathic pain following compression spinal cord injury in rats: relevance to its antioxidant and anti-inflammatory activities. — PubMed · 2022 · Journal Article
- TAZ Induces Migration of Microglia and Promotes Neurological Recovery After Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Tauroursodeoxycholic Acid Reduces Neuroinflammation but Does Not Support Long Term Functional Recovery of Rats with Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Selenium nanoparticles derived from Proteus mirabilis YC801 alleviate oxidative stress and inflammatory response to promote nerve repair in rats with spinal cord injury. — PubMed · 2022 · Journal Article
- The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation. — PubMed · 2022 · Journal Article
- An anti-inflammatory and neuroprotective biomimetic nanoplatform for repairing spinal cord injury. — PubMed · 2022 · Journal Article
- Neuroprotective Mechanisms of Ginsenoside Rb1 in Central Nervous System Diseases. — PubMed · 2022 · Journal Article
- Curcumin as a Promising Neuroprotective Agent for the Treatment of Spinal Cord Injury: A Review of the Literature. — PubMed · 2022 · Journal Article
- Lenalidomide improves H(2)O(2)-induced PC12 cell injury by blocking the Notch signaling pathway. — PubMed · 2022 · Journal Article
- Lithium promotes recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Protective effects of muscone on traumatic spinal cord injury in rats. — PubMed · 2022 · Journal Article
- Edaravone Modulates Neuronal GPX4/ACSL4/5-LOX to Promote Recovery After Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes. — PubMed · 2022 · Journal Article
- Melatonin as a Potential Neuroprotectant: Mechanisms in Subarachnoid Hemorrhage-Induced Early Brain Injury. — PubMed · 2022 · Journal Article
- Strategies for Biomaterial-Based Spinal Cord Injury Repair via the TLR4-NF-κB Signaling Pathway. — PubMed · 2022 · Journal Article
- Early mobilization in spinal cord injury promotes changes in microglial dynamics and recovery of motor function. — PubMed · 2022 · Journal Article
- Vagus Nerve Stimulation Reduces Neuroinflammation Through Microglia Polarization Regulation to Improve Functional Recovery After Spinal Cord Injury. — PubMed · 2022 · Journal Article
- S100A9 blockade improves the functional recovery after spinal cord injury via mediating neutrophil infiltration. — PubMed · 2022 · Journal Article
- Anti-Inflammatory CDGSH Iron-Sulfur Domain 2: A Biomarker of Central Nervous System Insult in Cellular, Animal Models and Patients. — PubMed · 2022 · Journal Article
- The Therapeutic Role of Exercise and Probiotics in Stressful Brain Conditions. — PubMed · 2022 · Journal Article
- Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells. — PubMed · 2022 · Journal Article
- Therapeutic Effect of Exosomes Derived From Stem Cells in Spinal Cord Injury: A Systematic Review Based on Animal Studies. — PubMed · 2022 · Systematic Review
- Bio-C (Modified Hyaluronic Acid-Coated-Collagen Tube) Implants Enable Functional Recovery after Complete Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Alendronate Enhances Functional Recovery after Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Treatment with Pulsed Extremely Low Frequency Electromagnetic Field (PELF-EMF) Exhibit Anti-Inflammatory and Neuroprotective Effect in Compression Spinal Cord Injury Model. — PubMed · 2022 · Journal Article
- Will Cannabigerol Trigger Neuroregeneration after a Spinal Cord Injury? An In Vitro Answer from NSC-34 Scratch-Injured Cells Transcriptome. — PubMed · 2022 · Journal Article
- L-Arginine Depletion Improves Spinal Cord Injury via Immunomodulation and Nitric Oxide Reduction. — PubMed · 2022 · Journal Article
- Bioengineered Zinc Oxide Nanoparticle-Loaded Hydrogel for Combinative Treatment of Spinal Cord Transection. — PubMed · 2022 · Journal Article
- Current Knowledge of Microglia in Traumatic Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Anti-repulsive guidance molecule: An antibody treatment in spinal cord injury — Crossref · 2022 · book-chapter
- Innate immune responses of glia and inflammatory cells in spinal cord injury — Crossref · 2022 · book-chapter
- Exosomes derived from olfactory ensheathing cells provided neuroprotection for spinal cord injury by switching the phenotype of macrophages/microglia. — PubMed · 2021 · Journal Article
- The Repression of the HMGB1-TLR4-NF-κB Signaling Pathway by Safflower Yellow May Improve Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Development of a New Formulation Based on In Situ Photopolymerized Polymer for the Treatment of Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Gold nanoclusters conjugated berberine reduce inflammation and alleviate neuronal apoptosis by mediating M2 polarization for spinal cord injury repair. — PubMed · 2021 · Journal Article
- Case report: "an unexpected origin of coma in a young adult". — PubMed · 2021 · Journal Article
- The Potential Therapeutic Effects of Agmatine, Methylprednisolone, and Rapamycin on Experimental Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Anti-inflammatory and antioxidative effects of genistein in a model of spinal cord injury in rats. — PubMed · 2021 · Journal Article
- Allografts for Skin Closure during In Utero Spina Bifida Repair in a Sheep Model. — PubMed · 2021 · Journal Article
- Genes and miRNAs as Hurdles and Promoters of Corticospinal Tract Regeneration in Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Distinct Polarization Dynamics of Microglia and Infiltrating Macrophages: A Novel Mechanism of Spinal Cord Ischemia/Reperfusion Injury. — PubMed · 2021 · Journal Article
- Therapeutic Effects of Risperidone against Spinal Cord Injury in a Rat Model of Asphyxial Cardiac Arrest: A Focus on Body Temperature, Paraplegia, Motor Neuron Damage, and Neuroinflammation. — PubMed · 2021 · Journal Article
- Long Non-coding RNAs and Circular RNAs: Insights Into Microglia and Astrocyte Mediated Neurological Diseases. — PubMed · 2021 · Journal Article
- Gut Microbiota Disorders Promote Inflammation and Aggravate Spinal Cord Injury Through the TLR4/MyD88 Signaling Pathway. — PubMed · 2021 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 13 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1741999 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 17 · accumulated records across collection walks 2063 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])