A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Lanthionine ketimine ester promotes locomotor recovery after spinal cord injury by reducing neuroinflammation and promoting axon growth. — PubMed · 2017 · Journal Article
- Newly Formed Endothelial Cells Regulate Myeloid Cell Activity Following Spinal Cord Injury via Expression of CD200 Ligand. — PubMed · 2017 · Journal Article
- Curcumin inhibits glial scar formation by suppressing astrocyte-induced inflammation and fibrosis in vitro and in vivo. — PubMed · 2017 · Journal Article
- Macrophage migration inhibitory factor activates inflammatory responses of astrocytes through interaction with CD74 receptor. — PubMed · 2017 · Journal Article
- Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment. — PubMed · 2017 · Journal Article
- Extremely low frequency magnetic field protects injured spinal cord from the microglia- and iron-induced tissue damage. — PubMed · 2017 · Journal Article
- Mitochondria Targeted Peptide Attenuates Mitochondrial Dysfunction, Controls Inflammation and Protects Against Spinal Cord Injury-Induced Lung Injury. — PubMed · 2017 · Journal Article
- Cell-Based Delivery of Interleukin-13 Directs Alternative Activation of Macrophages Resulting in Improved Functional Outcome after Spinal Cord Injury. — PubMed · 2016 · Journal Article
- IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury. — PubMed · 2016 · Journal Article
- Spinal cord injury modulates the lung inflammatory response in mechanically ventilated rats: a comparative animal study. — PubMed · 2016 · Comparative Study
- Activation of the niacin receptor HCA(2) reduces demyelination and neurofilament loss, and promotes functional recovery after spinal cord injury in mice. — PubMed · 2016 · Journal Article
- Age increases reactive oxygen species production in macrophages and potentiates oxidative damage after spinal cord injury. — PubMed · 2016 · Journal Article
- Regenerative Potential of Ependymal Cells for Spinal Cord Injuries Over Time. — PubMed · 2016 · Journal Article
- Nanoparticle-Delivered IRF5 siRNA Facilitates M1 to M2 Transition, Reduces Demyelination and Neurofilament Loss, and Promotes Functional Recovery After Spinal Cord Injury in Mice. — PubMed · 2016 · Journal Article
- A Coral-Derived Compound Improves Functional Recovery after Spinal Cord Injury through Its Antiapoptotic and Anti-Inflammatory Effects. — PubMed · 2016 · Journal Article
- Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke. — PubMed · 2016 · Journal Article
- [Helminth derived Immunomodulatory Glycan LNFP3 Impairs Pathogenesis of Peripheral Neuropathic Pain and Spinal Glial Activation]. — PubMed · 2016 · Journal Article
- Red LED photobiomodulation reduces pain hypersensitivity and improves sensorimotor function following mild T10 hemicontusion spinal cord injury. — PubMed · 2016 · Journal Article
- Anti-Inflammatory Mechanism of Neural Stem Cell Transplantation in Spinal Cord Injury. — PubMed · 2016 · Journal Article
- miR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair. — PubMed · 2016 · Journal Article
- Lumbar Myeloid Cell Trafficking into Locomotor Networks after Thoracic Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Unilateral microinjection of acrolein into thoracic spinal cord produces acute and chronic injury and functional deficits. — PubMed · 2016 · Journal Article
- TLR4 Deficiency Impairs Oligodendrocyte Formation in the Injured Spinal Cord. — PubMed · 2016 · Journal Article
- Interleukin-25 is detrimental for recovery after spinal cord injury in mice. — PubMed · 2016 · Journal Article
- Rescuing macrophage normal function in spinal cord injury with embryonic stem cell conditioned media. — PubMed · 2016 · Journal Article
- Adeno associated viral-mediated intraosseous labeling of bone marrow derived cells for CNS tracking. — PubMed · 2016 · Journal Article
- Spinal motor neurons are regenerated after mechanical lesion and genetic ablation in larval zebrafish. — PubMed · 2016 · Journal Article
- Tumor necrosis factor superfamily member APRIL contributes to fibrotic scar formation after spinal cord injury. — PubMed · 2016 · Journal Article
- A Hydrogel Bridge Incorporating Immobilized Growth Factors and Neural Stem/Progenitor Cells to Treat Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Basophils are dispensable for the recovery of gross locomotion after spinal cord hemisection injury. — PubMed · 2016 · Journal Article
- Differential effects of myelin basic protein-activated Th1 and Th2 cells on the local immune microenvironment of injured spinal cord. — PubMed · 2016 · Journal Article
- [EFFECTS OF BONE MARROW MESENCHYMAL STEM CELLS TRANSPLANTATION FOR TREATING RAT SPINAL CORD INJURY AND CYTOKINE EXPRESSION AT INJURY SITES]. — PubMed · 2016 · Journal Article
- Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury. — PubMed · 2016 · Journal Article
- Reactive astrocytes undergo M1 microglia/macrohpages-induced necroptosis in spinal cord injury. — PubMed · 2016 · Journal Article
- Spontaneous Recovery of Reflex Voiding Following Spinal Cord Injury Mediated by Anti-inflammatory and Neuroprotective Factors. — PubMed · 2016 · Journal Article
- Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines. — PubMed · 2016 · Journal Article
- Aldose Reductase Regulates Microglia/Macrophages Polarization Through the cAMP Response Element-Binding Protein After Spinal Cord Injury in Mice. — PubMed · 2016 · Journal Article
- Early modulation of pro-inflammatory microglia by minocycline loaded nanoparticles confers long lasting protection after spinal cord injury. — PubMed · 2016 · Journal Article
- Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice. — PubMed · 2016 · Journal Article
- Specificity of Toll-Like Receptor 2 and Dectin-1 Signaling in CNS Macrophages. — PubMed · 2015 · Journal Article
- Antiapoptotic Effect of Highly Secreted GMCSF From Neuronal Cell-specific GMCSF Overexpressing Neural Stem Cells in Spinal Cord Injury Model. — PubMed · 2015 · Journal Article
- Combination therapy of stem cell derived neural progenitors and drug delivery of anti-inhibitory molecules for spinal cord injury. — PubMed · 2015 · Journal Article
- Myeloid-Specific Blockade of Notch Signaling by RBP-J Knockout Attenuates Spinal Cord Injury Accompanied by Compromised Inflammation Response in Mice. — PubMed · 2015 · Journal Article
- Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury. — PubMed · 2015 · Journal Article
- T cell deficiency in spinal cord injury: altered locomotor recovery and whole-genome transcriptional analysis. — PubMed · 2015 · Journal Article
- Adult bone marrow mesenchymal and neural crest stem cells are chemoattractive and accelerate motor recovery in a mouse model of spinal cord injury. — PubMed · 2015 · Journal Article
- Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury. — PubMed · 2015 · Journal Article
- Delayed Imatinib Treatment for Acute Spinal Cord Injury: Functional Recovery and Serum Biomarkers. — PubMed · 2015 · Journal Article
- Effect of rutin on spinal cord injury through inhibition of the expression of MIP-2 and activation of MMP-9, and downregulation of Akt phosphorylation. — PubMed · 2015 · Journal Article
- Fluorescent Phosphorus Dendrimer as a Spectral Nanosensor for Macrophage Polarization and Fate Tracking in Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Sclerostin antibody preserves the morphology and structure of osteocytes and blocks the severe skeletal deterioration after motor-complete spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Treatment with curcumin alleviates sublesional bone loss following spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Biomaterial bridges enable regeneration and re-entry of corticospinal tract axons into the caudal spinal cord after SCI: Association with recovery of forelimb function. — PubMed · 2015 · Journal Article
- Temporal kinetics of macrophage polarization in the injured rat spinal cord. — PubMed · 2015 · Journal Article
- Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury. — PubMed · 2015 · Journal Article
- CD11d integrin blockade reduces the systemic inflammatory response syndrome after traumatic brain injury in rats. — PubMed · 2015 · Journal Article
- Efficacy of coenzyme Q10 in mitigating spinal cord injury-induced osteoporosis. — PubMed · 2015 · Journal Article
- Lack of galectin-3 improves the functional outcome and tissue sparing by modulating inflammatory response after a compressive spinal cord injury. — PubMed · 2015 · Journal Article
- Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice. — PubMed · 2015 · Journal Article
- Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury. — PubMed · 2015 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])