A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages. — PubMed · 2015 · Journal Article
- Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat. — PubMed · 2015 · Journal Article
- Early transplantation of mesenchymal stem cells after spinal cord injury relieves pain hypersensitivity through suppression of pain-related signaling cascades and reduced inflammatory cell recruitment. — PubMed · 2015 · Journal Article
- Polarized Macrophages Have Distinct Roles in the Differentiation and Migration of Embryonic Spinal-cord-derived Neural Stem Cells After Grafting to Injured Sites of Spinal Cord. — PubMed · 2015 · Journal Article
- The prognostic value of cerebrospinal fluid characteristics in dogs without deep pain perception due to thoracolumbar disc herniation. — PubMed · 2015 · Journal Article
- Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury. — PubMed · 2015 · Journal Article
- In vivo two-photon imaging of axonal dieback, blood flow, and calcium influx with methylprednisolone therapy after spinal cord injury. — PubMed · 2015 · Journal Article
- The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Macrophages in spinal cord injury: phenotypic and functional change from exposure to myelin debris. — PubMed · 2015 · Journal Article
- Adoptive transfer of M2 macrophages promotes locomotor recovery in adult rats after spinal cord injury. — PubMed · 2015 · Journal Article
- Decreased anti-regenerative effects after spinal cord injury in spry4-/- mice. — PubMed · 2015 · Journal Article
- Nanocarrier-mediated inhibition of macrophage migration inhibitory factor attenuates secondary injury after spinal cord injury. — PubMed · 2015 · Journal Article
- Effect of nimodipine on rat spinal cord injury. — PubMed · 2015 · Journal Article
- Carvedilol promotes neurological function, reduces bone loss and attenuates cell damage after acute spinal cord injury in rats. — PubMed · 2015 · Journal Article
- CCR5 blockade promotes M2 macrophage activation and improves locomotor recovery after spinal cord injury in mice. — PubMed · 2015 · Journal Article
- Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury. — PubMed · 2015 · Journal Article
- Biocompatibility of a coacervate-based controlled release system for protein delivery to the injured spinal cord. — PubMed · 2015 · Journal Article
- Chronic spinal cord lesions respond positively to tranplants of mesenchymal stem cells. — PubMed · 2015 · Journal Article
- Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair. — PubMed · 2015 · Journal Article
- Subdural infusion of dexamethasone inhibits leukomyelitis after acute spinal cord injury in a rat model. — PubMed · 2015 · Journal Article
- Transient activation of an adaptor protein, disabled-2, in rat spinal cord injury. — PubMed · 2015 · Journal Article
- Two-photon microscopy as a tool to investigate the therapeutic time window of methylprednisolone in a mouse spinal cord injury model. — PubMed · 2015 · Journal Article
- Brilliant blue G treatment facilitates regeneration after optic nerve injury in the adult rat. — PubMed · 2014 · Journal Article
- Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on glial scar formation after spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Ghrelin inhibits BSCB disruption/hemorrhage by attenuating MMP-9 and SUR1/TrpM4 expression and activation after spinal cord injury. — PubMed · 2014 · Journal Article
- Higenamine promotes M2 macrophage activation and reduces Hmgb1 production through HO-1 induction in a murine model of spinal cord injury. — PubMed · 2014 · Journal Article
- Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury. — PubMed · 2014 · Journal Article
- Intravital imaging of axonal interactions with microglia and macrophages in a mouse dorsal column crush injury. — PubMed · 2014 · Journal Article
- An acute growth factor treatment that preserves function after spinal cord contusion injury. — PubMed · 2014 · Journal Article
- Spatial and cellular characterization of mTORC1 activation after spinal cord injury reveals biphasic increase mainly attributed to microglia/macrophages. — PubMed · 2014 · Journal Article
- Beneficial effects of thymosin β4 on spinal cord injury in the rat. — PubMed · 2014 · Journal Article
- Effects of an immunomodulatory therapy and chondroitinase after spinal cord hemisection injury. — PubMed · 2014 · Journal Article
- Cerebrospinal fluid inflammatory cytokines and chemokines in naturally occurring canine spinal cord injury. — PubMed · 2014 · Journal Article
- Keratan sulfate expression is associated with activation of a subpopulation of microglia/macrophages in Wallerian degeneration. — PubMed · 2014 · Journal Article
- TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. — PubMed · 2014 · Journal Article
- Effects of low intensity vibration on bone and muscle in rats with spinal cord injury. — PubMed · 2014 · Evaluation Study
- Cytoprotective and anti-inflammatory effects of PAL31 overexpression in glial cells. — PubMed · 2014 · Journal Article
- IL-4 signaling drives a unique arginase+/IL-1β+ microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after traumatic spinal cord injury. — PubMed · 2014 · Journal Article
- The role of hemorrhage following spinal-cord injury. — PubMed · 2014 · Journal Article
- Blockade of IL-6 signaling by MR16-1 inhibits reduction of docosahexaenoic acid-containing phosphatidylcholine levels in a mouse model of spinal cord injury. — PubMed · 2014 · Journal Article
- CD36 deletion improves recovery from spinal cord injury. — PubMed · 2014 · Journal Article
- Complement C5a is detrimental to histological and functional locomotor recovery after spinal cord injury in mice. — PubMed · 2014 · Journal Article
- Immunohistochemical analysis of activin A expression in spinal cords of rats with clip compression injuries. — PubMed · 2014 · Journal Article
- Differences in the phagocytic response of microglia and peripheral macrophages after spinal cord injury and its effects on cell death. — PubMed · 2014 · Journal Article
- Two-photon-excited fluorescence microscopy as a tool to investigate the efficacy of methylprednisolone in a mouse spinal cord injury model. — PubMed · 2014 · Journal Article
- Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury. — PubMed · 2014 · Journal Article
- High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury. — PubMed · 2014 · Journal Article
- Inflammatory cascades mediate synapse elimination in spinal cord compression. — PubMed · 2014 · Journal Article
- Fgf2 improves functional recovery-decreasing gliosis and increasing radial glia and neural progenitor cells after spinal cord injury. — PubMed · 2014 · Journal Article
- Evaluation of mechanical properties and therapeutic effect of injectable self-assembling hydrogels for spinal cord injury. — PubMed · 2014 · Journal Article
- Mesenchymal stem cells improve locomotor recovery in traumatic spinal cord injury: systematic review with meta-analyses of rat models. — PubMed · 2014 · Journal Article
- Polymeric nanoparticle system to target activated microglia/macrophages in spinal cord injury. — PubMed · 2014 · Journal Article
- The neuroprotective effect of treatment with curcumin in acute spinal cord injury: laboratory investigation. — PubMed · 2014 · Comparative Study
- Compression injury in the mouse spinal cord elicits a specific proliferative response and distinct cell fate acquisition along rostro-caudal and dorso-ventral axes. — PubMed · 2013 · Journal Article
- Anabolic steroids reduce spinal cord injury-related bone loss in rats associated with increased Wnt signaling. — PubMed · 2013 · Journal Article
- Signaling proteins in spinal parenchyma and dorsal root ganglion in rat with spinal injury-induced spasticity. — PubMed · 2013 · Journal Article
- Extracellular matrix alterations, accelerated leukocyte infiltration and enhanced axonal sprouting after spinal cord hemisection in tenascin-C-deficient mice. — PubMed · 2013 · Journal Article
- Systemic iron chelation results in limited functional and histological recovery after traumatic spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Mobilisation of the splenic monocyte reservoir and peripheral CX₃CR1 deficiency adversely affects recovery from spinal cord injury. — PubMed · 2013 · Journal Article
- Temporal changes in monocyte and macrophage subsets and microglial macrophages following spinal cord injury in the Lys-Egfp-ki mouse model. — PubMed · 2013 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])