A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Differences in cytokine gene expression profile between acute and secondary injury in adult rat spinal cord. — PubMed · 2003 · Journal Article
- Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing. — PubMed · 2003 · Journal Article
- Vaccination with dendritic cells pulsed with peptides of myelin basic protein promotes functional recovery from spinal cord injury. — PubMed · 2003 · Journal Article
- Differential temporal expression of matrix metalloproteinases after spinal cord injury: relationship to revascularization and wound healing. — PubMed · 2003 · Journal Article
- Features of skin-coincubated macrophages that promote recovery from spinal cord injury. — PubMed · 2003 · Journal Article
- Hematogenous macrophages express CD8 and distribute to regions of lesion cavitation after spinal cord injury. — PubMed · 2003 · Journal Article
- Rats and mice exhibit distinct inflammatory reactions after spinal cord injury. — PubMed · 2003 · Comparative Study
- Upregulation of phospholipase D1 in the spinal cords of rats with clip compression injury. — PubMed · 2003 · Comparative Study
- Decreased neural damage after spinal cord injury in tPA-deficient mice. — PubMed · 2003 · Journal Article
- Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events. — PubMed · 2002 · Journal Article
- Treatment of spinal cord impact injury in the rat with transforming growth factor-beta. — PubMed · 2002 · Comparative Study
- The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation. — PubMed · 2002 · Journal Article
- Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion. — PubMed · 2002 · Journal Article
- Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors. — PubMed · 2002 · Journal Article
- Expression of TGFbeta2 but not TGFbeta1 correlates with the deposition of scar tissue in the lesioned spinal cord. — PubMed · 2002 · Journal Article
- Efficacy of methylprednisolone therapy for the injured rat spinal cord. — PubMed · 2002 · Journal Article
- Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats. — PubMed · 2002 · Journal Article
- Expression of tenascin R and J1 mRNA in motoneurons after a traumatic lesion in the spinal cord. — PubMed · 2001 · Journal Article
- AIF-1 expression defines a proliferating and alert microglial/macrophage phenotype following spinal cord injury in rats. — PubMed · 2001 · Journal Article
- Acute up-regulation of brain-derived neurotrophic factor expression resulting from experimentally induced injury in the rat spinal cord. — PubMed · 2001 · Journal Article
- Support of axonal regrowth by endogenous mechanisms following spinal cord injury in adult rats. — PubMed · 2001 · Journal Article
- Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord. — PubMed · 2001 · Journal Article
- Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord. — PubMed · 2001 · Journal Article
- Giant multinucleated macrophages occur in acute spinal cord injury. — PubMed · 2001 · Journal Article
- Regenerating descending axons preferentially reroute to the gray matter in the presence of a general macrophage/microglial reaction caudal to a spinal transection in adult zebrafish. — PubMed · 2001 · Journal Article
- Nitric oxide via macrophage iNOS induces apoptosis following traumatic spinal cord injury. — PubMed · 2000 · Journal Article
- Brain-derived neurotrophic factor in astrocytes, oligodendrocytes, and microglia/macrophages after spinal cord injury. — PubMed · 2000 · Journal Article
- Sustained induction of heme oxygenase-1 in the traumatized spinal cord. — PubMed · 2000 · Journal Article
- Up-regulation of glial cell line-derived neurotrophic factor (GDNF) following traumatic spinal cord injury. — PubMed · 2000 · Journal Article
- Co-induction of HSP70 and heme oxygenase-1 in macrophages and glia after spinal cord contusion in the rat. — PubMed · 2000 · Journal Article
- Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: a potential new anti-inflammatory treatment. — PubMed · 2000 · Journal Article
- Persistent accumulation of cyclooxygenase-1 (COX-1) expressing microglia/macrophages and upregulation by endothelium following spinal cord injury. — PubMed · 2000 · Journal Article
- Calpain activity and expression increased in activated glial and inflammatory cells in penumbra of spinal cord injury lesion. — PubMed · 2000 · Journal Article
- The macrophage in acute neural injury: changes in cell numbers over time and levels of cytokine production in mammalian central and peripheral nervous systems. — PubMed · 2000 · Journal Article
- Localization of transforming growth factor-beta1 and receptor mRNA after experimental spinal cord injury. — PubMed · 2000 · Journal Article
- Cytokine chemokine expression in contused rat spinal cord. — PubMed · 2000 · Journal Article
- Leukaemia inhibitory factor is required for normal inflammatory responses to injury in the peripheral and central nervous systems in vivo and is chemotactic for macrophages in vitro. — PubMed · 2000 · Journal Article
- Modulation of macrophage and microglial responses to axonal injury in the peripheral and central nervous systems. — PubMed · 1999 · Journal Article
- Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. — PubMed · 1999 · Journal Article
- Long-term effects of methylprednisolone following transection of adult rat spinal cord. — PubMed · 1999 · Journal Article
- Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury. — PubMed · 1999 · Journal Article
- Potential repair of rat spinal cord injuries using stimulated homologous macrophages. — PubMed · 1999 · Journal Article
- Differential activation of microglia after experimental spinal cord injury. — PubMed · 1999 · Journal Article
- Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats. — PubMed · 1998 · Journal Article
- Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis. — PubMed · 1998 · Journal Article
- Spontaneous longitudinally orientated axonal regeneration is associated with the Schwann cell framework within the lesion site following spinal cord compression injury of the rat. — PubMed · 1998 · Journal Article
- Induction of heme oxygenase-1 (HO-1) in the contused spinal cord of the rat. — PubMed · 1998 · Journal Article
- Acute inflammatory response in spinal cord following impact injury. — PubMed · 1998 · Journal Article
- Traumatic spinal cord injury induces nuclear factor-kappaB activation. — PubMed · 1998 · Journal Article
- Two- and three-dimensional computer graphic evaluation of the subacute spinal cord injury. — PubMed · 1998 · Journal Article
- Effects of macrophage transplantation in the injured adult rat spinal cord: a combined immunocytochemical and biochemical study. — PubMed · 1998 · Journal Article
- Activated macrophage/microglial cells can promote the regeneration of sensory axons into the injured spinal cord. — PubMed · 1997 · Journal Article
- Activated macrophages and the blood-brain barrier: inflammation after CNS injury leads to increases in putative inhibitory molecules. — PubMed · 1997 · Journal Article
- Endogenous repair after spinal cord contusion injuries in the rat. — PubMed · 1997 · Journal Article
- Effects of pro-inflammatory cytokines in experimental spinal cord injury. — PubMed · 1997 · Journal Article
- [Identification of macrophage migration inhibitory factor (MIF) in rat spinal cord and its kinetics on experimental spinal cord injury]. — PubMed · 1997 · English Abstract
- Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. — PubMed · 1997 · Journal Article
- Steps to recovery. Researchers finding ways of coaxing spinal nerves to grow. — PubMed · 1997 · News
- Comparison of the growth and fate of fetal spinal iso- and allografts in the adult rat injured spinal cord. — PubMed · 1996 · Comparative Study
- Genetic influences on cellular reactions to spinal cord injury: a wound-healing response present in normal mice is impaired in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration. — PubMed · 1996 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])