A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Quinolinic acid accumulation and functional deficits following experimental spinal cord injury. — PubMed · 1995 · Journal Article
- Adhesive/repulsive properties in the injured spinal cord: relation to myelin phagocytosis by invading macrophages. — PubMed · 1994 · Journal Article
- Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury. — PubMed · 1994 · Journal Article
- Characterization of photochemically induced spinal cord injury in the rat by light and electron microscopy. — PubMed · 1994 · Journal Article
- Effects of silica on the outcome from experimental spinal cord injury: implication of macrophages in secondary tissue damage. — PubMed · 1994 · Journal Article
- Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. — PubMed · 1994 · Journal Article
- Complete prevention of postischemic spinal cord injury by means of regional infusion with hypothermic saline and adenosine. — PubMed · 1994 · Journal Article
- Elevation of the neurotoxin quinolinic acid occurs following spinal cord trauma. — PubMed · 1994 · Journal Article
- Increased levels of the excitotoxin quinolinic acid in spinal cord following contusion injury. — PubMed · 1993 · Journal Article
- Protection from postischemic spinal cord injury by perfusion cooling of the epidural space. — PubMed · 1993 · Comparative Study
- Differential expression of carbonic anhydrase isozymes in microglial cell types. — PubMed · 1993 · Comparative Study
- [Experimental study of acute spinal cord injury: a histopathological study]. — PubMed · 1993 · English Abstract
- Role of adult oligodendrocytes in remyelination after neural injury. — PubMed · 1992 · Journal Article
- Chronic cervical compressive myelopathy in horses: clinical correlations with spinal cord alterations. — PubMed · 1991 · Journal Article
- The electrolytic lesion as a model of spinal cord damage and repair in the adult rat. — PubMed · 1991 · Journal Article
- Monocytes become macrophages; they do not become microglia: a light and electron microscopic autoradiographic study using 125-iododeoxyuridine. — PubMed · 1986 · Journal Article
- Delayed demyelination and macrophage invasion: a candidate for secondary cell damage in spinal cord injury. — PubMed · 1985 · Journal Article
- An ultrastructural study on the reactive oligodendrocytes, myeloclasts, and myelophages in transected dog spinal cord. — PubMed · 1980 · Journal Article
- [Reparative regeneration of cat spinal cord nerve fibers]. — PubMed · 1980 · Comparative Study
- Studies on cell-mediated hypersensitivity to neural antigens after experimental spinal cord injury. — PubMed · 1977 · Journal Article
- The relationship between microglia and brain macrophages. Experimental investigations. — PubMed · 1975 · Journal Article
- Pressure-induced lesions in the spinal cord of rabbits. — PubMed · 1974 · Journal Article
- Early axonal changes following lesions of the dorsal columns in rats. — PubMed · 1974 · Journal Article
- Cell proliferation in injured spinal cord. An electron microscopic study. — PubMed · 1973 · Journal Article
- Radiation-induced cellular changes in traumatic spinal cord injury. — PubMed · 1969 · Journal Article
- Fine-structural changes of myelin sheaths after axonal degeneration in the spinal cord of rats. — PubMed · 1966 · Journal Article
Indexed as laboratory work
- A Polydopamine-coated Engineered Type II Collagen Scaffold for Motor Neuron Organization and Spinal Cord Injury Regeneration. — PubMed · 2026 · Journal Article
- Human spinal cord microglia/macrophages culture: Accutase digestion and non-enzymatic purification. — PubMed · 2025 · Journal Article
- Engineered Extracellular Vesicles from Antler Blastema Progenitor Cells: A Therapeutic Choice for Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Construction and optimization of a coculture system of mouse brain microvascular endothelial cells and myelin debris. — PubMed · 2023 · Journal Article
- Bile acids attenuate PKM2 pathway activation in proinflammatory microglia. — PubMed · 2022 · Journal Article
- D-dopachrome tautomerase activates COX2/PGE(2) pathway of astrocytes to mediate inflammation following spinal cord injury. — PubMed · 2021 · Journal Article
- The Effect of Inflammatory Priming on the Therapeutic Potential of Mesenchymal Stromal Cells for Spinal Cord Repair. — PubMed · 2021 · Journal Article
- Engineering Microenvironment for Endogenous Neural Regeneration after Spinal Cord Injury by Reassembling Extracellular Matrix. — PubMed · 2020 · Journal Article
- IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury. — PubMed · 2020 · Journal Article
- TGF-β Secretion by M2 Macrophages Induces Glial Scar Formation by Activating Astrocytes In Vitro. — PubMed · 2019 · Journal Article
- Effect of Differently Polarized Macrophages on Proliferation and Differentiation of Ependymal Cells from Adult Spinal Cord. — PubMed · 2019 · Journal Article
- Regulatory effects of dermal papillary pluripotent stem cells on polarization of macrophages from M1 to M2 phenotype in vitro. — PubMed · 2019 · Journal Article
- Polycaprolactone/polysialic acid hybrid, multifunctional nanofiber scaffolds for treatment of spinal cord injury. — PubMed · 2018 · Journal Article
- Effect of hyaluronic acid hydrogels containing astrocyte-derived extracellular matrix and/or V2a interneurons on histologic outcomes following spinal cord injury. — PubMed · 2018 · Journal Article
- Differently polarized macrophages affect the viability and growth of NSPCs by regulating the expression of PACAP. — PubMed · 2017 · Journal Article
- Regulation of RhoA by STAT3 coordinates glial scar formation. — PubMed · 2017 · Journal Article
- Bone marrow-derived mesenchymal stem cells in three-dimensional culture promote neuronal regeneration by neurotrophic protection and immunomodulation. — PubMed · 2016 · Journal Article
- CCL2 Mediates Neuron-Macrophage Interactions to Drive Proregenerative Macrophage Activation Following Preconditioning Injury. — PubMed · 2015 · Journal Article
- Cellular transplantation-based evolving treatment options in spinal cord injury. — PubMed · 2015 · Journal Article
- Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation. — PubMed · 2014 · Journal Article
- Programmed death 1 deficiency induces the polarization of macrophages/microglia to the M1 phenotype after spinal cord injury in mice. — PubMed · 2014 · Journal Article
- Selective nanovector mediated treatment of activated proinflammatory microglia/macrophages in spinal cord injury. — PubMed · 2013 · Journal Article
- Culturing microglia from the neonatal and adult central nervous system. — PubMed · 2013 · Journal Article
- Spatio-temporal development of axonopathy in canine intervertebral disc disease as a translational large animal model for nonexperimental spinal cord injury. — PubMed · 2013 · Journal Article
- Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury. — PubMed · 2012 · Journal Article
- Nanofibrous collagen nerve conduits for spinal cord repair. — PubMed · 2012 · Journal Article
- Prominent microglial activation in the early proinflammatory immune response in naturally occurring canine spinal cord injury. — PubMed · 2011 · Journal Article
- Schwann cell coculture improves the therapeutic effect of bone marrow stromal cells on recovery in spinal cord-injured mice. — PubMed · 2011 · Journal Article
- A phase 2 autologous cellular therapy trial in patients with acute, complete spinal cord injury: pragmatics, recruitment, and demographics. — PubMed · 2010 · Clinical Trial, Phase II
- Interaction of NG2(+) glial progenitors and microglia/macrophages from the injured spinal cord. — PubMed · 2010 · Journal Article
- Fibrin-based tissue engineering scaffolds enhance neural fiber sprouting and delay the accumulation of reactive astrocytes at the lesion in a subacute model of spinal cord injury. — PubMed · 2010 · Journal Article
- Tumor necrosis factor alpha enhances glutamatergic transmission onto spinal motoneurons. — PubMed · 2010 · Journal Article
- Transplantation of human marrow stromal cells and mono-nuclear bone marrow cells into the injured spinal cord: a comparative study. — PubMed · 2009 · Comparative Study
- Macrophages and inflammatory mediators in chemical toxicity: a battle of forces. — PubMed · 2009 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])