A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
The source has not said who or what was studied
- Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization. — PubMed · 2023 · Journal Article
- Induced pluripotent stem cells as natural biofactories for exosomes carrying miR-199b-5p in the treatment of spinal cord injury. — PubMed · 2023 · Journal Article
- Macrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis. — PubMed · 2023 · Preprint
- Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Biomaterials delivery strategies to repair spinal cord injury by modulating macrophage phenotypes. — PubMed · 2022 · Journal Article
- Silk-Elastin-like Polymers for Acute Intraparenchymal Treatment of the Traumatically Injured Spinal Cord: A First Systematic Experimental Approach. — PubMed · 2022 · Journal Article
- Novel therapeutic approach to slow down the inflammatory cascade in acute/subacute spinal cord injury: Early immune therapy with lipopolysaccharide enhanced neuroprotective effect of combinational therapy of granulocyte colony-stimulating factor and bone-marrow mesenchymal stem cell in spinal cord injury. — PubMed · 2022 · Journal Article
- Electroconductive PEDOT nanoparticle integrated scaffolds for spinal cord tissue repair. — PubMed · 2022 · Journal Article
- Sustained release of hydrogen sulfide from anisotropic ferrofluid hydrogel for the repair of spinal cord injury. — PubMed · 2022 · Journal Article
- Cerium Oxide Nanoparticles Alleviate Neuropathic Pain by Modulating Macrophage Polarization in a Rat SCI Model. — PubMed · 2022 · Journal Article
- Characterization of microglia/macrophage phenotypes in the spinal cord following intervertebral disc herniation. — PubMed · 2022 · Journal Article
- Exosomes derived from M2 Macrophages Improve Angiogenesis and Functional Recovery after Spinal Cord Injury through HIF-1α/VEGF Axis. — PubMed · 2022 · Journal Article
- D-dopachrome tautomerase drives astroglial inflammation via NF-κB signaling following spinal cord injury. — PubMed · 2022 · Journal Article
- Reducing host aldose reductase activity promotes neuronal differentiation of transplanted neural stem cells at spinal cord injury sites and facilitates locomotion recovery. — PubMed · 2022 · Journal Article
- Moxibustion exhibits therapeutic effects on spinal cord injury via modulating microbiota dysbiosis and macrophage polarization — Crossref · 2022 · journal-article
- Mesenchymal Stem Cell-Derived Exosomal MiRNAs Promote M2 Macrophages Polarization: Therapeutic Opportunities for Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Macrophage Migration Inhibitory Factor (MIF) Makes Complex Contributions to Pain-Related Hyperactivity of Nociceptors after Spinal Cord Injury. — PubMed · 2022 · Journal Article
- The Inflammatory Response after Moderate Contusion Spinal Cord Injury: A Time Study. — PubMed · 2022 · Journal Article
- Effects of amyloid precursor protein peptide APP96-110, alone or with human mesenchymal stromal cells, on recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Characterization of Ex Vivo and In Vitro Wnt Transcriptome Induced by Spinal Cord Injury in Rat Microglial Cells. — PubMed · 2022 · Journal Article
- Genistein Protects against Spinal Cord Injury in Mice by Inhibiting Neuroinflammation via TLR4-Mediated Microglial Polarization. — PubMed · 2022 · Journal Article The source marks this record as retracted.
- Agathisflavone as a Single Therapy or in Association With Mesenchymal Stem Cells Improves Tissue Repair in a Spinal Cord Injury Model in Rats. — PubMed · 2022 · Journal Article
- Corrigendum to 'Berberine-loaded M2 macrophage-derived exosomes for spinal cord injury therapy' [Acta Biomaterialia 126 (2021) 211-223]. — PubMed · 2022 · Published Erratum
- Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress. — PubMed · 2022 · Journal Article
- Regulatory Role of Mesenchymal Stem Cells on Secondary Inflammation in Spinal Cord Injury. — PubMed · 2022 · Journal Article
- L-Arginine Depletion Improves Spinal Cord Injury via Immunomodulation and Nitric Oxide Reduction. — PubMed · 2022 · Journal Article
- A New and Simple Method for Spinal Cord Injury Induction in Mice. — PubMed · 2022 · Journal Article
- Sodium alginate and naloxone loaded macrophage-derived nanovesicles for the treatment of spinal cord injury. — PubMed · 2022 · Journal Article
- Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Accelerate Functional Recovery After Spinal Cord Injury by Promoting the Phagocytosis of Macrophages to Clean Myelin Debris. — PubMed · 2021 · Journal Article
- Low-dose metformin treatment in the subacute phase improves the locomotor function of a mouse model of spinal cord injury. — PubMed · 2021 · Journal Article
- Bone Marrow Mesenchymal Stem Cell-Derived Exosome-Educated Macrophages Promote Functional Healing After Spinal Cord Injury. — PubMed · 2021 · Journal Article
- VX-765 reduces neuroinflammation after spinal cord injury in mice. — PubMed · 2021 · Journal Article
- Effect of Humic Acid on Oxidative Stress and Neuroprotection in Traumatic Spinal Cord Injury: An Experimental Study. — PubMed · 2021 · Journal Article
- Macrophage membrane-mediated targeted drug delivery for treatment of spinal cord injury regardless of the macrophage polarization states — Crossref · 2021 · journal-article
- Ninjurin-1: a biomarker for reflecting the process of neuroinflammation after spinal cord injury. — PubMed · 2021 · Journal Article
- MitoQ Promotes M2-Like Macrophage/Microglia Polarization And Attenuates Apoptosis After Spinal Cord Injury Through Mitochondria-Dependent Pathway — Crossref · 2021 · posted-content
- Ivermectin-functionalized multiwall carbon nanotube enhanced the locomotor activity and neuropathic pain by modulating M1/M2 macrophage and decrease oxidative stress in rat model of spinal cord injury. — PubMed · 2021 · Journal Article The source marks this record as retracted.
- Imaging of Inflammation in Spinal Cord Injury: Novel Insights on the Usage of PFC-Based Contrast Agents. — PubMed · 2021 · Journal Article
- Mechanism of mesenchymal stem cells in spinal cord injury repair through macrophage polarization — Crossref · 2021 · journal-article
- More attention on glial cells to have better recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- Human adipose tissue- and umbilical cord-derived stem cells: which is a better alternative to treat spinal cord injury? — PubMed · 2020 · Journal Article
- Neural stem cells induce M2 polarization of macrophages through the upregulation of interleukin-4. — PubMed · 2020 · Journal Article
- Current Insights Into the Pathology of Canine Intervertebral Disc Extrusion-Induced Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats. — PubMed · 2020 · Journal Article
- Parthenolide promotes the repair of spinal cord injury by modulating M1/M2 polarization via the NF-κB and STAT 1/3 signaling pathway. — PubMed · 2020 · Journal Article
- Neuroprotective Effect of Subdural Infusion of Serp-1 in Spinal Cord Trauma. — PubMed · 2020 · Journal Article
- "Median paralyzing dose" and "multiple regression analysis", a new viewpoint to the research method of spinal cord injury. — PubMed · 2020 · Journal Article
- Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Local Serpin Treatment via Chitosan-Collagen Hydrogel after Spinal Cord Injury Reduces Tissue Damage and Improves Neurologic Function. — PubMed · 2020 · Journal Article
- Butylphthalide has an Anti-Inflammatory Role in Spinal Cord Injury by Promoting Macrophage/Microglia M2 Polarization via p38 Phosphorylation — Crossref · 2020 · journal-article
- Berberine-Loaded M2 Macrophage-Derived Exosomes for Spinal Cord Injury Therapy — Crossref · 2020 · posted-content
- Decellularized brain matrix enhances macrophage polarization and functional improvements in rat spinal cord injury — Crossref · 2020 · journal-article
- LncGBP9/miR-34a axis modulates macrophage M1/M2 polarization to affect spinal cord injury repair via STAT1/STAT6 and SOCS3 — Crossref · 2019 · posted-content
- PLG Bridge Implantation in Chronic SCI Promotes Axonal Elongation and Myelination. — PubMed · 2019 · Journal Article
- Relationship of Inflammatory Cytokines From M1-Type Microglia/Macrophages at the Injured Site and Lumbar Enlargement With Neuropathic Pain After Spinal Cord Injury in the CCL21 Knockout (plt) Mouse. — PubMed · 2019 · Journal Article
- Delayed Azithromycin Treatment Improves Recovery After Mouse Spinal Cord Injury. — PubMed · 2019 · Journal Article
- The Role of Neuronal Factors in the Epigenetic Reprogramming of Microglia in the Normal and Diseased Central Nervous System. — PubMed · 2019 · Journal Article
- Silencing of the MEKK2/MEKK3 Pathway Protects against Spinal Cord Injury via the Hedgehog Pathway and the JNK Pathway. — PubMed · 2019 · Journal Article The source marks this record as retracted.
- Inhibition of MALT1 paracaspase activity improves lesion recovery following spinal cord injury. — PubMed · 2019 · Journal Article
- MicroRNAs in Microglia: How do MicroRNAs Affect Activation, Inflammation, Polarization of Microglia and Mediate the Interaction Between Microglia and Glioma? — PubMed · 2019 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 2 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1037078 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 4 · accumulated records across collection walks 1301 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])