A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
The source has not said who or what was studied
- Concomitant Traumatic Brain Injury Exacerbates Endotheliopathy in Patients with Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Sustained-Release Spermidine Hydrogel Inhibits M1 Macrophage Polarization and Promotes Tissue Repair for Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
- Novel diagnostic biomarkers associated with macrophage-microglia in spinal cord injury — Crossref · 2025 · journal-article
- Structure-Inspired Lineage-Specific Matrix for Endogenous Neurogenesis in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Iridoids derived from Valeriana jatamansi Jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathway. — PubMed · 2025 · Journal Article
- Enhancement of spinal cord injury repair in rats using photo-crosslinked GelMA hydrogel combined with mitochondrial transplantation. — PubMed · 2025 · Journal Article
- Macrophage Migration Inhibitory Factor Suppresses Natural Killer Cell Response and Promotes Hypoimmunogenic Stem Cell Engraftment Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Usp18 Mediates D-Dopachrome Tautomerase-Induced Astrocytic Inflammation After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Commentary: Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury. — PubMed · 2025 · Journal Article
- Precision Nanotherapy for Spinal Cord Injury: Modulating SLC16A3 With Methylprednisolone-Loaded Nanoparticles. — PubMed · 2025 · Journal Article
- Redefining macrophage phenotypes after spinal cord injury: An open data approach — Crossref · 2025 · journal-article
- Curcumin-loaded polydopamine nanoparticles-based antioxidant scaffold promote spinal cord repair though dural-regulation of macrophage polarization. — PubMed · 2025 · Journal Article
- Mature neutrophils promote long-term functional recovery after spinal cord injury in a sex-dependent manner. — PubMed · 2025 · Journal Article
- Macrophage Migration Inhibitory Factor Suppresses Natural Killer Cell Response and Promotes Hypoimmunogenic Stem Cell Engraftment Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury. — PubMed · 2025 · Journal Article
- Macrophage- and pluripotent-like reparative Muse cells are unique endogenous stem cells distinct from other somatic stem cells. — PubMed · 2025 · Journal Article
- A Scoping Review of Exosome Delivery Applications in Hair Loss. — PubMed · 2025 · Journal Article
- Controlled release of MIF siRNA and GDNF protein from a photocurable scaffold efficiently repairs spinal cord injury. — PubMed · 2025 · Journal Article
- Retraction notice to "Ivermectin-functionalized multiwall carbon nanotube enhanced the locomotor activity and neuropathic pain by modulating M1/M2 macrophage and decrease oxidative stress in rat model of spinal cord injury" [Heliyon 7 (2021) e07311]. — PubMed · 2025 · Journal Article
- Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury. — PubMed · 2025 · Journal Article
- Research Progress on Stem Cell Regulation of Macrophage Polarization in Promoting Spinal Cord Injury Recovery in Stem Cell Transplantation — Crossref · 2024 · journal-article
- Bioinspired conductive oriented nanofiber felt with efficient ROS clearance and anti-inflammation for inducing M2 macrophage polarization and accelerating spinal cord injury repair. — PubMed · 2024 · Journal Article
- Macrophage Polarization-Based Biomaterials for Repairing Spinal Cord Injury — Crossref · 2024 · journal-article
- Cytosolic Phospholipase A2 in Infiltrating Monocyte-Derived Macrophages Does Not Impair Recovery After Spinal Cord Injury in Female Mice. — PubMed · 2024 · Journal Article
- Galectin-3 inhibition reduces fibrotic scarring and promotes functional recovery after spinal cord injury in mice. — PubMed · 2024 · Journal Article
- Inosine Improves Functional Recovery and Cell Morphology Following Compressive Spinal Cord Injury in Mice. — PubMed · 2024 · Journal Article
- Small extracellular vesicles from hypoxia-preconditioned bone marrow mesenchymal stem cells attenuate spinal cord injury via miR-146a-5p-mediated regulation of macrophage polarization. — PubMed · 2024 · Journal Article
- Targeting transcription factor pu.1 for improving neurologic outcomes after spinal cord injury. — PubMed · 2024 · Journal Article
- Elevated phagocytic capacity directs innate spinal cord repair. — PubMed · 2024 · Journal Article
- Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment. — PubMed · 2024 · Journal Article
- Upregulation of circ0000381 attenuates microglial/macrophage pyroptosis after spinal cord injury. — PubMed · 2024 · Journal Article
- Non-resolving neuroinflammation regulates axon regeneration in chronic spinal cord injury. — PubMed · 2024 · Preprint
- Regeneration in Mice of Injured Skin, Heart, and Spinal Cord by α-Gal Nanoparticles Recapitulates Regeneration in Amphibians. — PubMed · 2024 · Journal Article
- Biocompatible adipose extracellular matrix and reduced graphene oxide nanocomposite for tissue engineering applications. — PubMed · 2024 · Journal Article
- Ablation of the integrin CD11b mac-1 limits deleterious responses to traumatic spinal cord injury and improves functional recovery in mice. — PubMed · 2024 · Preprint
- Retraction Note: Hydralazine Promotes Central Nervous System Recovery after Spinal Cord Injury by Suppressing Oxidative Stress and Inflammation through Macrophage Regulation. — PubMed · 2024 · Retraction Notice
- Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury. — PubMed · 2024 · Journal Article
- Unveiling the role of tRNA-derived small RNAs in MAPK signaling pathway: implications for cancer and beyond. — PubMed · 2024 · Journal Article
- Retracted: The Conditioned Medium of Lactobacillus rhamnoides GG Regulates Microglia/Macrophage Polarization and Improves Functional Recovery after Spinal Cord Injury in Rats — Crossref · 2024 · journal-article The source marks this record as retracted.
- The GLP-1 receptor agonist exenatide improves recovery from spinal cord injury by inducing macrophage polarization toward the M2 phenotype — Crossref · 2024 · journal-article
- Mesenchymal stem cells overexpressing XIST induce macrophage M2 polarization and improve neural stem cell homeostatic microenvironment, alleviating spinal cord injury. — PubMed · 2024 · Journal Article
- Macrophage polarization in spinal cord injury repair and the possible role of microRNAs: A review — Crossref · 2023 · journal-article
- Mesenchymal Stem Cells Combined With Electroacupuncture Treatment Regulate the Subpopulation of Macrophages and Astrocytes to Facilitate Axonal Regeneration in Transected Spinal Cord. — PubMed · 2023 · Journal Article
- Bibliometric and visual analysis of spinal cord injury-associated macrophages from 2002 to 2023. — PubMed · 2023 · Systematic Review
- Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis. — PubMed · 2023 · Journal Article
- CD1d-dependent neuroinflammation impairs tissue repair and functional recovery following a spinal cord injury. — PubMed · 2023 · Preprint
- Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos. — PubMed · 2023 · Journal Article
- Quantitative biochemical phenotypic heterogeneity of macrophages after myelin debris phagocytosis at a single cell level by synchrotron radiation fourier transform infrared microspectroscopy. — PubMed · 2023 · Journal Article
- Macrophage migration inhibitory factor facilitates astrocytic production of the CCL2 chemokine following spinal cord injury. — PubMed · 2023 · Journal Article
- Potential targets and mechanisms of photobiomodulation for spinal cord injury. — PubMed · 2023 · Journal Article
- UTX deletion promotes M2 macrophage polarization by epigenetically regulating endothelial cell-macrophage crosstalk after spinal cord injury — Crossref · 2023 · journal-article
- Mechanism of M2 macrophages modulating astrocyte polarization through the TGF-β/PI3K/Akt pathway. — PubMed · 2023 · Journal Article
- Identification of Cathepsin B as a Therapeutic Target for Ferroptosis of Macrophage after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury. — PubMed · 2023 · Journal Article
- The pathogenesis of DLD-mediated cuproptosis induced spinal cord injury and its regulation on immune microenvironment. — PubMed · 2023 · Journal Article
- Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Small extracellular vesicles derived from four dimensional-culture of mesenchymal stem cells induce alternatively activated macrophages by upregulating IGFBP2/EGFR to attenuate inflammation in the spinal cord injury of rats. — PubMed · 2023 · Journal Article
- Effects of Whole-Body Vibration and Manually Assisted Locomotor Therapy on Neurotrophin-3 Expression and Microglia/Macrophage Mobilization Following Thoracic Spinal Cord Injury in Rats. — PubMed · 2023 · Journal Article
- Microglial activating transcription factor 3 upregulation: An indirect target to attenuate inflammation in the nervous system. — PubMed · 2023 · Journal Article
- Early treatment with dapsone after spinal cord injury in rats decreases the inflammatory response and promotes long-term functional recovery. — PubMed · 2023 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 2 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1037078 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 4 · accumulated records across collection walks 1301 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])