A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Immune modulatory therapies for spinal cord injury--past, present and future. — PubMed · 2014 · Journal Article
- Is neuroinflammation in the injured spinal cord different than in the brain? Examining intrinsic differences between the brain and spinal cord. — PubMed · 2014 · Comparative Study
- CNS repair requires both effector and regulatory T cells with distinct temporal and spatial profiles. — PubMed · 2014 · Journal Article
- Inducible protein-10, a potential driver of neurally controlled interleukin-10 and morbidity in human blunt trauma. — PubMed · 2014 · Comparative Study
- Decorin blocks scarring and cystic cavitation in acute and induces scar dissolution in chronic spinal cord wounds. — PubMed · 2014 · Journal Article
- Identification of distinct monocyte phenotypes and correlation with circulating cytokine profiles in acute response to spinal cord injury: a pilot study. — PubMed · 2014 · Comparative Study
- Short hairpin RNA against PTEN enhances regenerative growth of corticospinal tract axons after spinal cord injury. — PubMed · 2013 · Journal Article
- Pilot study: elevated circulating levels of the proinflammatory cytokine macrophage migration inhibitory factor in patients with chronic spinal cord injury. — PubMed · 2013 · Journal Article
- The prevalence and phenotype of activated microglia/macrophages within the spinal cord of the hyperostotic mouse (twy/twy) changes in response to chronic progressive spinal cord compression: implications for human cervical compressive myelopathy. — PubMed · 2013 · Journal Article
- [Pathogenesis of spinal cord injuries and mechanisms of repair induced by olfactory ensheathing cells]. — PubMed · 2013 · English Abstract
- Comparison of mesenchymal stromal cells from human bone marrow and adipose tissue for the treatment of spinal cord injury. — PubMed · 2013 · Journal Article
- The effect of Lycium barbarum on spinal cord injury, particularly its relationship with M1 and M2 macrophage in rats. — PubMed · 2013 · Journal Article
- Early loss of pericytes and perivascular stromal cell-induced scar formation after stroke. — PubMed · 2013 · Clinical Trial
- [Management of multiple myeloma-related bone disease]. — PubMed · 2013 · English Abstract
- Managing inflammation after spinal cord injury through manipulation of macrophage function. — PubMed · 2013 · Journal Article
- A combination of taxol infusion and human umbilical cord mesenchymal stem cells transplantation for the treatment of rat spinal cord injury. — PubMed · 2012 · Journal Article
- Beneficial effects of αB-crystallin in spinal cord contusion injury. — PubMed · 2012 · Journal Article
- Autologous incubated macrophage therapy in acute, complete spinal cord injury: results of the phase 2 randomized controlled multicenter trial. — PubMed · 2012 · Clinical Trial, Phase II
- From bench to beside to cure spinal cord injury: lost in translation? — PubMed · 2012 · Journal Article
- Encapsulated mesenchymal stromal cells for in vivo transplantation. — PubMed · 2011 · Journal Article
- Repertoire of microglial and macrophage responses after spinal cord injury. — PubMed · 2011 · Journal Article
- Spinal cord injury therapies in humans: an overview of current clinical trials and their potential effects on intrinsic CNS macrophages. — PubMed · 2011 · Journal Article
- PDE 7 inhibitors: new potential drugs for the therapy of spinal cord injury. — PubMed · 2011 · Journal Article
- Experimental reconstruction of the injured spinal cord. — PubMed · 2011 · Journal Article
- Establishing a model spinal cord injury in the African green monkey for the preclinical evaluation of biodegradable polymer scaffolds seeded with human neural stem cells. — PubMed · 2010 · Journal Article
- Immunoglobulin G: a potential treatment to attenuate neuroinflammation following spinal cord injury. — PubMed · 2010 · Journal Article
- The enigmatic roles of microglial versus neuronal progranulin in neurological disease. — PubMed · 2010 · Journal Article
- Taking advantage of the systemic immune system to cure brain diseases. — PubMed · 2009 · Journal Article
- Identification of BLyS (B lymphocyte stimulator), a non-myelin-associated protein, as a functional ligand for Nogo-66 receptor. — PubMed · 2009 · Journal Article
- Pilot Study: The Role of Macrophage Migration Inhibitory Factor (MIF) in Spinal Cord Injury — ClinicalTrials.gov · 2009 · Observational · Completed
- Novel roles for Nogo receptor in inflammation and disease. — PubMed · 2008 · Journal Article
- TGF-beta1 and TGF-beta2 expression after traumatic human spinal cord injury. — PubMed · 2008 · Journal Article
- Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial. — PubMed · 2007 · Clinical Trial, Phase I
- SPARC from olfactory ensheathing cells stimulates Schwann cells to promote neurite outgrowth and enhances spinal cord repair. — PubMed · 2007 · Comparative Study
- Matrix metalloproteinases and their inhibitors in human traumatic spinal cord injury. — PubMed · 2007 · Journal Article
- Subacute human spinal cord contusion: few lymphocytes and many macrophages. — PubMed · 2007 · Case Reports
- The cellular inflammatory response in human spinal cords after injury. — PubMed · 2006 · Journal Article
- MR imaging of lineage-restricted neural precursors following transplantation into the adult spinal cord. — PubMed · 2006 · Journal Article
- Gene delivery to the spinal cord: comparison between lentiviral, adenoviral, and retroviral vector delivery systems. — PubMed · 2006 · Comparative Study
- 6-Shogaol, a natural product, reduces cell death and restores motor function in rat spinal cord injury. — PubMed · 2006 · Journal Article
- Survival and migration of human and rat olfactory ensheathing cells in intact and injured spinal cord. — PubMed · 2006 · Comparative Study
- Drug evaluation: ProCord - a potential cell-based therapy for spinal cord injury. — PubMed · 2006 · Journal Article
- Immune-based therapy for spinal cord repair: autologous macrophages and beyond. — PubMed · 2006 · Journal Article
- Characterization of non-neuronal elements within fibronectin mats implanted into the damaged adult rat spinal cord. — PubMed · 2006 · Journal Article
- Macrophage migration inhibitory factor induces cell death and decreases neuronal nitric oxide expression in spinal cord neurons. — PubMed · 2006 · Journal Article
- Spinal cord compression as a result of Rosai-Dorfman disease of the upper cervical spine in a child. — PubMed · 2005 · Case Reports
- Chemokines, chemokine receptors and pain. — PubMed · 2005 · Journal Article
- Complete cord injury. — PubMed · 2005 · Comment
- Treatment of complete spinal cord injury patients by autologous bone marrow cell transplantation and administration of granulocyte-macrophage colony stimulating factor. — PubMed · 2005 · Journal Article
- Inflammatory-mediated injury and repair in the traumatically injured spinal cord. — PubMed · 2005 · Journal Article
- Macrophages and dendritic cells treatment of spinal cord injury: from the bench to the clinic. — PubMed · 2005 · Journal Article
- Synthes Award for Resident Research on Spinal Cord and Spinal Column Injury: granulocyte macrophage colony stimulating factor (GM-CSF) prevents apoptosis and improves functional outcome in experimental spinal cord contusion injury. — PubMed · 2005 · Journal Article
- Neuroprotection from complement-mediated inflammatory damage. — PubMed · 2004 · Journal Article
- A monoclonal antibody to CD11d reduces the inflammatory infiltrate into the injured spinal cord: a potential neuroprotective treatment. — PubMed · 2004 · Comparative Study
- Early expression and cellular localization of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in human traumatic spinal cord injury. — PubMed · 2004 · Journal Article
- A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury. — PubMed · 2004 · Comparative Study
- Spinal cord injury induces lesional expression of the proinflammatory and antiangiogenic cytokine EMAP II. — PubMed · 2003 · Comparative Study
- Autologous Incubated Macrophages for Patients With Complete Spinal Cord Injuries — ClinicalTrials.gov · 2003 · Interventional · Suspended
- Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth. — PubMed · 2002 · Journal Article
- Transplant mediated repair of the central nervous system: an imminent solution? — PubMed · 2002 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])