A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Clodronate liposomes: perspectives in research and therapeutics. — PubMed · 2002 · Journal Article
- [Transplants as a therapy after spinal cord injury]. — PubMed · 2002 · English Abstract
- Disuse osteoporosis. — PubMed · 2001 · Journal Article
- Inducible nitric oxide synthase in the bladder of spinal cord injured patients with a chronic indwelling urinary catheter. — PubMed · 2001 · Journal Article
- Immunological approaches to the treatment of spinal cord injury. — PubMed · 2001 · Journal Article
- Major histocompatibility complex class II expression by activated microglia caudal to lesions of descending tracts in the human spinal cord is not associated with a T cell response. — PubMed · 2000 · Journal Article
- Known and plausible modulators of depressed immune functions following spinal cord injuries. — PubMed · 2000 · Journal Article
- Autoimmune involvement in CNS trauma is beneficial if well controlled. — PubMed · 2000 · Journal Article
- Immunological regulation of neuronal degeneration and regeneration in the injured spinal cord. — PubMed · 2000 · Journal Article
- Poly(alpha-hydroxyacids) for application in the spinal cord: resorbability and biocompatibility with adult rat Schwann cells and spinal cord. — PubMed · 1998 · Comparative Study
- Increased osteoclast-like cells formation in long-term bone marrow cultures from patients with a spinal cord injury. — PubMed · 1998 · Journal Article
- Spinal cord injury: bridging the lesion and the role of neurotrophic factors in repair. — PubMed · 1998 · Journal Article
- Upregulated expression of chemokines in herniated nucleus pulposus resorption. — PubMed · 1996 · Journal Article
- The role of bisphosphonates in the treatment of bone metastases--the U.S. experience. — PubMed · 1996 · Clinical Trial
- The kynurenine pathway and neurologic disease. Therapeutic strategies. — PubMed · 1996 · Journal Article
- Bone histomorphometry in men with spinal osteoporosis. — PubMed · 1995 · Journal Article
- Effects of tiludronate on bone loss in paraplegic patients. — PubMed · 1995 · Clinical Trial
- Macrophage responses to central and peripheral nerve injury. — PubMed · 1993 · Journal Article
- Macrophages and inflammatory damage in spinal cord injury. — PubMed · 1992 · Journal Article
- Cortical osteoclasts are less sensitive to etidronate than trabecular osteoclasts. — PubMed · 1991 · Journal Article
- Effects of a 120 day period of bed-rest on bone mass and bone cell activities in man: attempts at countermeasure. — PubMed · 1987 · Journal Article
- Microglia, monocytes, and macrophages. — PubMed · 1981 · Journal Article
- Cellular inflammatory response. Findings in patients with neurological diseases. — PubMed · 1974 · Journal Article
- Schwann cells and peripheral myelin within human central nervous tissues: the mesenchymal character of Schwann cells. — PubMed · 1971 · Journal Article
- The pathogenesis of Pott's paraplegia. — PubMed · 1967 · Journal Article
Indexed as work in animals
- Dual-engineered imDC-exosome-IKVAV nanovesicles spatiotemporally remodel the neuro-immune microenvironment for spinal cord repair. — PubMed · 2026 · Journal Article
- Lgals3(high) macrophages orchestrate neuroinflammation and extracellular matrix remodelling via NF-κB pathway in acute spinal cord injury. — PubMed · 2026 · Journal Article
- A printable blue-light photocurable gelatin methacryloyl/silk fibroin hydrogel loaded with salvianolic acid B for enhanced spinal cord repair. — PubMed · 2026 · Journal Article
- Every-Other-Day Fasting Prehabilitation Attenuates Secondary Injury Following Spinal Cord Injury and Is Associated with Stage-Dependent SREBP1-Related Metabolic-Immune Remodeling. — PubMed · 2026 · Journal Article
- Integrative single-cell and bulk transcriptomic analyses identify a microglia-associated NAGLU signature linked to disulfidptosis-associated transcriptional patterns after spinal cord injury. — PubMed · 2026 · Journal Article
- Network-guided identification and in vitro/in vivo validation of Withaferin A as an inhibitor of nuclear factor kappa B for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Photo-crosslinkable quaternized chitosan-based hydrogel for immunomodulation and functional recovery in spinal cord injury. — PubMed · 2026 · Journal Article
- Polydopamine-functionalized 3D-printed scaffold co-loaded with resveratrol and NGF for enhanced neuronal differentiation under inflammatory stress. — PubMed · 2026 · Journal Article
- Piezo1 promote macrophage-to-myofibroblast transition and bladder fibrosis in neurogenic bladder. — PubMed · 2026 · Journal Article
- KDM6A/MMP-3 epigenetic axis governs macrophage senescence after spinal cord injury for mediating the regenerative niche to promote neurological repair. — PubMed · 2026 · Journal Article
- Tetramethylpyrazine promotes spinal cord injury repair by modulating macrophage M1/M2 polarization via inhibition of the IL-6/JAK2/STAT3 pathway. — PubMed · 2026 · Journal Article
- The Canonical Wnt Surrogate Agonist scFv-Dkk1c Ameliorates Spinal Cord Injury in Rats. — PubMed · 2026 · Journal Article
- Elevated phagocytic capacity directs innate spinal cord repair. — PubMed · 2026 · Journal Article
- Activation of the Reverse Cholesterol Transport Pathway: A Strategy to Ameliorate Lipid Metabolic Dyshomeostasis in the Microenvironment Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Molecular Mechanism of M2 Macrophage-Derived Extracellular Vesicles in Alleviating Inflammation in Rats with Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Engineered CCR2 positive macrophages coordinate immunoregulation with neural regeneration and matrix remodeling after spinal cord injury. — PubMed · 2026 · Journal Article
- Temporal and spatial-adapted metal ions delivery system for spinal cord injury repair with Mg-Zn-doped bilayer bioactive glasses. — PubMed · 2026 · Journal Article
- Varenicline-mediated cholinergic activation through α4β2 nAChR inhibits microglial neuroinflammation and alleviates neuropathic pain and depression following spinal cord injury. — PubMed · 2026 · Journal Article
- Depleting non-resolving neuroinflammation in chronic spinal cord injury attenuates thermal hypersensitivity. — PubMed · 2026 · Journal Article
- Multifunctional Nanozyme Hydrogel for Oxidative Stress Scavenging and Mitophagy Activation in Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- A reparative neutrophil subpopulation accelerates spinal cord regeneration in zebrafish by controlling macrophage inflammation via Il-4. — PubMed · 2026 · Journal Article
- Impeding glial scarring hyperplasia and activating axon neogenesis via immunomodulatory microneedle patch for spinal cord repair. — PubMed · 2026 · Journal Article
- ABCA1-mediated lipid efflux restrains oxidative stress and neuroinflammation after spinal cord injury. — PubMed · 2026 · Journal Article
- M2 Macrophage-Derived Osteopontin Promotes Osteogenesis of Fibro-Adipogenic Progenitors After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Multi-omics mapping identifies a C/EBPβ-S100a4⁺ macrophage axis as a therapeutic target in acute spinal cord injury. — PubMed · 2026 · Journal Article
- Macrophages warrant Mauthner cell axon regrowth by preventing late-stage hyperglycemia in zebrafish. — PubMed · 2026 · Journal Article
- PLX5622 did not alter anxiety-like behaviour and showed limited microglial depletion efficacy in a spinal cord injury model in female rats. — PubMed · 2026 · Journal Article
- Metformin-Loaded Schwann Cell Exosomes Reprogram Macrophages and Enhance Neurogenesis in Spinal Cord Injury Through PI3K/AKT Activation. — PubMed · 2026 · Journal Article
- Repetitive trans-spinal magnetic stimulation promotes repair in inflammatory spinal cord injury through sex-dependent immune modulation. — PubMed · 2026 · Journal Article
- SYK-dependent lipid handling in monocyte-derived macrophages governs functional recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Injectable Metal-Free Carbon Dot-Integrated Hydrogel for Regulating Inflammation via Macrophage Metabolic Reprograming in Spinal Cord Injury Therapy. — PubMed · 2026 · Journal Article
- APOE-mediated lipid transport prevents C1q-related synaptic loss after spinal cord injury via attenuating macrophage lipid stress. — PubMed · 2026 · Journal Article
- FGF4 activates FGFR1 - PI3K/AKT signaling to enhance Clec10a-mediated intracellular myelin debris processing and promote spinal cord repair. — PubMed · 2026 · Journal Article
- A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Liposome-encapsulated clodronate and COX-2 inhibitor treatment impair ventilatory recovery but improve compensatory locomotor function following cervical spinal cord injury in rats. — PubMed · 2026 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])