A subject this map covers
Myelin inhibitor blockade
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Lifting the inhibitory myelin signals that stop a fibre growing.
What does not belong here, however close it looks
Remyelination to restore conduction is a different aim — the oligodendrocyte-progenitor concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 124 records · 1983–2026
- Indexed as work in animals: 268 records · 1977–2025
- Indexed as laboratory work: 19 records · 1986–2018
- The source has not said who or what was studied: 58 records · 2002–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
469 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Lost in translation: why pharmacological trials keep failing in acute spinal cord injury. — PubMed · 2026 · Journal Article
- Enhanced clinical trial stratification in spinal cord injury: the value of electrophysiology. — PubMed · 2026 · Journal Article
- Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors. — PubMed · 2025 · Journal Article
- Safety and efficacy of intrathecal antibodies to Nogo-A in patients with acute cervical spinal cord injury: a randomised, double-blind, multicentre, placebo-controlled, phase 2b trial. — PubMed · 2025 · Journal Article
- Development of neural repair therapy for chronic spinal cord trauma: soluble Nogo receptor decoy from discovery to clinical trial. — PubMed · 2023 · Review
- Conus medullaris syndrome as a presenting feature of MOG-associated disease. — PubMed · 2023 · Case Reports
- Dynamic induction of the myelin-associated growth inhibitor Nogo-A in perilesional plasticity regions after human spinal cord injury. — PubMed · 2023 · Journal Article
- Immunomodulation induced by central nervous system-related peptides as a therapeutic strategy for neurodegenerative disorders. — PubMed · 2021 · Journal Article
- Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions. — PubMed · 2021 · Journal Article
- Strategies to neutralize RhoA/ROCK pathway after spinal cord injury. — PubMed · 2021 · Journal Article
- The Implication of Reticulons (RTNs) in Neurodegenerative Diseases: From Molecular Mechanisms to Potential Diagnostic and Therapeutic Approaches. — PubMed · 2021 · Journal Article
- hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats. — PubMed · 2021 · Journal Article
- Treatment of neurogenic lower urinary tract symptoms: main contributions from 2018 and 2019. — PubMed · 2020 · Journal Article
- A proteolytic C-terminal fragment of Nogo-A (reticulon-4A) is released in exosomes and potently inhibits axon regeneration. — PubMed · 2020 · Journal Article
- Nogo BACE jumps on the exosome. — PubMed · 2020 · Journal Article
- AXER-204 in Participants With Chronic Spinal Cord Injury — ClinicalTrials.gov · 2019 · Interventional · Completed
- Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke. — PubMed · 2019 · Journal Article
- Cell fate regulation by reticulon-4 in human prostate cancers. — PubMed · 2019 · Journal Article
- NEP(1-40)-modified human serum albumin nanoparticles enhance the therapeutic effect of methylprednisolone against spinal cord injury. — PubMed · 2019 · Journal Article
- Effect of exosomes derived from MiR-133b-modified ADSCs on the recovery of neurological function after SCI. — PubMed · 2019 · Journal Article
- Axonal damage is remarkable in patients with acutely worsening symptoms of compression myelopathy: biomarkers in cerebrospinal fluid samples. — PubMed · 2018 · Journal Article
- First-in-Man Intrathecal Application of Neurite Growth-Promoting Anti-Nogo-A Antibodies in Acute Spinal Cord Injury. — PubMed · 2018 · Clinical Trial, Phase I
- Human olfactory mesenchymal stromal cell transplants promote remyelination and earlier improvement in gait co-ordination after spinal cord injury. — PubMed · 2017 · Journal Article
- Nogo-A Antibodies for Progressive Multiple Sclerosis. — PubMed · 2017 · Journal Article
- Traumatic Spinal Cord Injury-Repair and Regeneration. — PubMed · 2017 · Journal Article
- Assessment of Neuroprotective Properties of Melissa officinalis in Combination With Human Umbilical Cord Blood Stem Cells After Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Application of q-Space Diffusion MRI for the Visualization of White Matter. — PubMed · 2016 · Journal Article
- Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation. — PubMed · 2016 · Journal Article
- Cornel Iridoid Glycoside Improves Locomotor Impairment and Decreases Spinal Cord Damage in Rats. — PubMed · 2016 · Journal Article
- Experimental and Clinical Advances in Immunotherapy Strategies for Spinal Cord Injury Target on MAIs and Their Receptors. — PubMed · 2016 · Journal Article
- Myelin oligodendrocyte glycoprotein (MOG35-55)-induced experimental autoimmune encephalomyelitis is ameliorated in interleukin-32 alpha transgenic mice. — PubMed · 2015 · Journal Article
- Anti-Nogo-A antibody: a treatment option for neurogenic lower urinary tract dysfunction? — PubMed · 2015 · Journal Article
- Superman and the Swiss Continence Foundation. — PubMed · 2015 · Editorial
- Human NgR-Fc decoy protein via lumbar intrathecal bolus administration enhances recovery from rat spinal cord contusion. — PubMed · 2014 · Journal Article
- Structural features of the Nogo receptor signaling complexes at the neuron/myelin interface. — PubMed · 2014 · Journal Article
- Nogo limits neural plasticity and recovery from injury. — PubMed · 2014 · Journal Article
- CNS repair requires both effector and regulatory T cells with distinct temporal and spatial profiles. — PubMed · 2014 · Journal Article
- Seronegative Neuromyelitis Optica Spectrum--the challenges on disease definition and pathogenesis. — PubMed · 2014 · Case Reports
- Critical role for PAR1 in kallikrein 6-mediated oligodendrogliopathy. — PubMed · 2013 · Journal Article
- Where no synapses go: gatekeepers of circuit remodeling and synaptic strength. — PubMed · 2013 · Journal Article
- Therapeutics targeting Nogo-A hold promise for stroke restoration. — PubMed · 2013 · Journal Article
- A 32-year-old male with brainstem lesions. — PubMed · 2013 · Case Reports
- Treating spinal cord injury in rats with a combination of human fetal neural stem cells and hydrogels modified with serotonin. — PubMed · 2013 · Journal Article
- Management strategies for acute spinal cord injury: current options and future perspectives. — PubMed · 2012 · Journal Article
- Inhibition of Nogo expression to promote repair after spinal cord injury. — PubMed · 2012 · Journal Article
- Dependence of regenerated sensory axons on continuous neurotrophin-3 delivery. — PubMed · 2012 · Journal Article
- The role of Nogo-A in axonal plasticity, regrowth and repair. — PubMed · 2012 · Journal Article
- Autoreactivity against myelin basic protein in patients with chronic paraplegia. — PubMed · 2012 · Journal Article
- The role of Nogo-A in neuroregeneration: a review. — PubMed · 2012 · Journal Article
- From bench to beside to cure spinal cord injury: lost in translation? — PubMed · 2012 · Journal Article
- The use of a gold nanoparticle-based adjuvant to improve the therapeutic efficacy of hNgR-Fc protein immunization in spinal cord-injured rats. — PubMed · 2011 · Journal Article
- Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. — PubMed · 2011 · Journal Article
- Spinal cord injury: taking a detour to recovery (Commentary on Schnell et al.). — PubMed · 2011 · Journal Article
- SOD1 overexpression improves features of the oligodendrocyte precursor response in vitro. — PubMed · 2011 · Journal Article
- Ganglioside mediate the interaction between Nogo receptor 1 and LINGO-1. — PubMed · 2011 · Journal Article
- A systematic review of directly applied biologic therapies for acute spinal cord injury. — PubMed · 2011 · Journal Article
- Movement rehabilitation after spinal cord injuries: emerging concepts and future directions. — PubMed · 2011 · Journal Article
- Combined NgR vaccination and neural stem cell transplantation promote functional recovery after spinal cord injury in adult rats. — PubMed · 2011 · Journal Article
- TAT-NEP1-40 as a novel therapeutic candidate for axonal regeneration and functional recovery after stroke. — PubMed · 2011 · Journal Article
- Paired immunoglobulin-like receptor B knockout does not enhance axonal regeneration or locomotor recovery after spinal cord injury. — PubMed · 2011 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 1 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1641516 · this programme has 49 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it has nothing | asked on 2026-10-12 | the source found 0 · this programme has 452 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("anti-Nogo" OR "Nogo-A antibody" OR "myelin associated inhibitor") - Crossref
spinal cord injury anti-Nogo Nogo-A antibody - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Myelin Proteins"[MeSH Terms] OR "Nogo Proteins"[MeSH Terms] OR "anti-Nogo"[Title/Abstract] OR "Nogo-A antibody"[Title/Abstract] OR "myelin associated inhibitor"[Title/Abstract])