A subject this map covers
Myelin inhibitor blockade
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Lifting the inhibitory myelin signals that stop a fibre growing.
What does not belong here, however close it looks
Remyelination to restore conduction is a different aim — the oligodendrocyte-progenitor concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 124 records · 1983–2026
- Indexed as work in animals: 268 records · 1977–2025
- Indexed as laboratory work: 19 records · 1986–2018
- The source has not said who or what was studied: 58 records · 2002–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
469 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- T cell responses to myelin basic protein in patients with spinal cord injury and multiple sclerosis. — PubMed · 1999 · Comparative Study
- Regeneration of injured axons in the adult mammalian central nervous system. — PubMed · 1997 · Journal Article
- [Enzyme-linked immunoadsorbent assays for myelin basic protein and antibodies to myelin basic protein in serum and CSF of patients with diseases of the nervous system]. — PubMed · 1995 · English Abstract
- Systemic humoral factors participating in the course of spinal cord injury. — PubMed · 1983 · Journal Article
Indexed as work in animals
- Improving neuronal recovery in spinal cord injury with NEP1-40-modified neural stem cells through RhoA/ROCK signaling pathway modulation. — PubMed · 2025 · Journal Article
- Preemptive Propofol Administration in Spinal Cord Injury: Effects on Pain-Induced Hypertension, Neuroinflammation, and Functional Recovery in Rats. — PubMed · 2025 · Journal Article
- Modulation of the biphasic pattern of cortical reorganization in spinal cord-transected rats by external magnetic fields. — PubMed · 2025 · Journal Article
- Inhibition of the Nogo-pathway in experimental spinal cord injury: a meta-analysis of 76 experimental treatments. — PubMed · 2023 · Meta-Analysis
- Amino-terminal proteolytic fragment of the axon growth inhibitor Nogo-A (Rtn4A) is upregulated by injury and promotes axon regeneration. — PubMed · 2023 · Journal Article
- Electroacupuncture-Regulated miR-34a-3p/PDCD6 Axis Promotes Post-Spinal Cord Injury Recovery in Both In Vitro and In Vivo Settings. — PubMed · 2022 · Journal Article
- Development of Neurogenic Detrusor Overactivity after Thoracic Spinal Cord Injury Is Accompanied by Time-Dependent Changes in Lumbosacral Expression of Axonal Growth Regulators. — PubMed · 2022 · Journal Article
- Assessment of the Oral Delivery of a Myelin Basic Protein Gene Promoter with Antiapoptotic bcl-x(L) (pMBP-bcl-x(L)) DNA by Cyclic Peptide Nanotubes with Two Aspect Ratios and Its Biodistribution in the Brain and Spinal Cord. — PubMed · 2021 · Journal Article
- Activation of skeletal muscle-resident glial cells upon nerve injury. — PubMed · 2021 · Journal Article
- NEP1-40-overexpressing Neural Stem Cells Enhance Axon Regeneration by Inhibiting Nogo-A/NgR1 Signaling Pathway. — PubMed · 2021 · Journal Article
- Effects of repetitive magnetic stimulation on motor function and GAP43 and 5-HT expression in rats with spinal cord injury. — PubMed · 2020 · Journal Article
- Complement C6 deficiency exacerbates pathophysiology after spinal cord injury. — PubMed · 2020 · Journal Article
- NOGO-A immunolabeling is present in glial cells and some neurons of the recovering lumbar spinal cord in lizards. — PubMed · 2020 · Journal Article
- Nogo receptor decoy promotes recovery and corticospinal growth in non-human primate spinal cord injury. — PubMed · 2020 · Journal Article
- Combined with anti-Nogo-A antibody treatment, BDNF did not compensate the extra deleterious motor effect caused by large size cervical cord hemisection in adult macaques. — PubMed · 2020 · Journal Article
- Oligonucleotide-functionalized hydrogels for sustained release of small molecule (aptamer) therapeutics. — PubMed · 2020 · Journal Article
- Combination Therapy With Hyperbaric Oxygen and Erythropoietin Inhibits Neuronal Apoptosis and Improves Recovery in Rats With Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Cell-seeded porous silk fibroin scaffolds promotes axonal regeneration and myelination in spinal cord injury rats. — PubMed · 2019 · Journal Article
- Anti-Nogo-A Antibodies As a Potential Causal Therapy for Lower Urinary Tract Dysfunction after Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Plexina2 and CRMP2 Signaling Complex Is Activated by Nogo-A-Liganded Ngr1 to Restrict Corticospinal Axon Sprouting after Trauma. — PubMed · 2019 · Journal Article
- Low sulfated heparins target multiple proteins for central nervous system repair. — PubMed · 2019 · Journal Article
- Implications of immunotherapy with high-dose glatiramer acetate in acute phase of spinal cord injury in rats. — PubMed · 2019 · Journal Article
- LOTUS Inhibits Neuronal Apoptosis and Promotes Tract Regeneration in Contusive Spinal Cord Injury Model Mice. — PubMed · 2018 · Journal Article
- Changes of motor corticobulbar projections following different lesion types affecting the central nervous system in adult macaque monkeys. — PubMed · 2018 · Journal Article
- Overexpression of HIPK2 attenuates spinal cord injury in rats by modulating apoptosis, oxidative stress, and inflammation. — PubMed · 2018 · Journal Article
- Feasibility study on mouse live imaging after spinal cord injury and poly(lactide-co-glycolide) bridge implantation. — PubMed · 2018 · Journal Article
- The human natural killer-1 (HNK-1) glycan mimetic ursolic acid promotes functional recovery after spinal cord injury in mouse. — PubMed · 2018 · Journal Article
- A Small Organic Compound Mimicking the L1 Cell Adhesion Molecule Promotes Functional Recovery after Spinal Cord Injury in Zebrafish. — PubMed · 2018 · Journal Article
- Effects of MicroRNA-494 on Astrocyte Proliferation and Synaptic Remodeling in the Spinal Cord of a Rat Model of Chronic Compressive Spinal Cord Injury by Regulating the Nogo/Ngr Signaling Pathway. — PubMed · 2018 · Journal Article The source marks this record as retracted.
- Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury. — PubMed · 2018 · Journal Article
- Comparison of RNAi NgR and NEP1-40 in Acting on Axonal Regeneration After Spinal Cord Injury in Rat Models. — PubMed · 2017 · Comparative Study
- Protease activated receptor 2 controls myelin development, resiliency and repair. — PubMed · 2017 · Journal Article
- Withaferin A protects against spinal cord injury by inhibiting apoptosis and inflammation in mice. — PubMed · 2017 · Journal Article
- Myelination of axons emerging from neural progenitor grafts after spinal cord injury. — PubMed · 2017 · Journal Article
- Local injection of Lenti-Olig2 at lesion site promotes functional recovery of spinal cord injury in rats. — PubMed · 2017 · Journal Article
- Myelin Basic Protein Regulates Primitive and Definitive Neural Stem Cell Proliferation from the Adult Spinal Cord. — PubMed · 2017 · Journal Article
- Resistance of interleukin-6 to the extracellular inhibitory environment promotes axonal regeneration and functional recovery following spinal cord injury. — PubMed · 2017 · Journal Article
- Kinematic gait parameters are highly sensitive measures of motor deficits and spinal cord injury in mice subjected to experimental autoimmune encephalomyelitis. — PubMed · 2017 · Journal Article
- Intraspinal transplantation of subventricular zone-derived neural progenitor cells improves phrenic motor output after high cervical spinal cord injury. — PubMed · 2017 · Journal Article
- Lentiviral Vector-Mediated p27(kip1) Expression Facilitates Recovery After Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Protective effects of BMP-7 against tumor necrosis factor α-induced oligodendrocyte apoptosis. — PubMed · 2016 · Journal Article
- The Neurite Outgrowth Inhibitory Nogo-A-Δ20 Region Is an Intrinsically Disordered Segment Harbouring Three Stretches with Helical Propensity. — PubMed · 2016 · Journal Article
- NT-3 promotes proprioceptive axon regeneration when combined with activation of the mTor intrinsic growth pathway but not with reduction of myelin extrinsic inhibitors. — PubMed · 2016 · Journal Article
- Myelin Basic Protein Cleaves Cell Adhesion Molecule L1 and Improves Regeneration After Injury. — PubMed · 2016 · Journal Article
- Long-term production of BDNF and NT-3 induced by A91-immunization after spinal cord injury. — PubMed · 2016 · Journal Article
- Interleukin-25 is detrimental for recovery after spinal cord injury in mice. — PubMed · 2016 · Journal Article
- Knockdown of Nogo gene by short hairpin RNA interference promotes functional recovery of spinal cord injury in a rat model. — PubMed · 2016 · Journal Article
- Local Delivery of Neurotrophin-3 and Anti-NogoA Promotes Repair After Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Semi-automated counting of axon regeneration in poly(lactide co-glycolide) spinal cord bridges. — PubMed · 2016 · Journal Article
- Spinal cord injury repair by implantation of structured hyaluronic acid scaffold with PLGA microspheres in the rat. — PubMed · 2016 · Journal Article
- A novel Nogo-66 receptor antagonist peptide promotes neurite regeneration in vitro. — PubMed · 2016 · Journal Article
- Differential effects of myelin basic protein-activated Th1 and Th2 cells on the local immune microenvironment of injured spinal cord. — PubMed · 2016 · Journal Article
- ROCK inhibition with fasudil promotes early functional recovery of spinal cord injury in rats by enhancing microglia phagocytosis. — PubMed · 2016 · Journal Article
- X-ray therapy promotes structural regeneration after spinal cord injury in a rat model. — PubMed · 2016 · Evaluation Study
- Beneficial effects of local profound hypothermia and the possible mechanism after experimental spinal cord injury in rats. — PubMed · 2016 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 1 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1641516 · this programme has 49 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it has nothing | asked on 2026-10-12 | the source found 0 · this programme has 452 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("anti-Nogo" OR "Nogo-A antibody" OR "myelin associated inhibitor") - Crossref
spinal cord injury anti-Nogo Nogo-A antibody - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Myelin Proteins"[MeSH Terms] OR "Nogo Proteins"[MeSH Terms] OR "anti-Nogo"[Title/Abstract] OR "Nogo-A antibody"[Title/Abstract] OR "myelin associated inhibitor"[Title/Abstract])