A subject this map covers
Neuropathic pain
What belongs here
Pain arising from damage to the nervous system itself, and everything used to treat it.
What does not belong here, however close it looks
Mechanical shoulder pain from wheelchair overuse is a separate, orthopaedic subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1478 records · 1957–2026
- Indexed as work in animals: 615 records · 1992–2026
- Indexed as laboratory work: 13 records · 1994–2019
- The source has not said who or what was studied: 509 records · 1972–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2615 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- RUNX1 Induces Central Neuropathic Pain by Activating Microglia and Triggering the Inflammatory Response in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- CGRP(+) fibers sprout within gastrocnemius muscle following complete spinal cord injury in rodents. — PubMed · 2025 · Journal Article
- Contusive spinal cord injury causes Nav1.8 dysfunction to upregulate small sensory neuron excitability. — PubMed · 2025 · Journal Article
- Injectable ROS homeostasis protective hydrogel inhibiting microglial ferroptosis through the Nrf2/Slc7a11/Gpx4 to alleviate neuropathic pain and promote spinal cord injury repair. — PubMed · 2025 · Journal Article
- The Analgesic and Antispastic Effects of Epidural Spinal Stimulation Depending on the Frequency and Intensity After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Isolation, characterization and testing of RNA aptamers targeting glutamate receptors in a rat spinal cord injury pain model. — PubMed · 2025 · Journal Article
- Neuropathic Pain-Like Responses in a Chronic CNS Injury Model Are Mediated by Corticospinal-Targeted Spinal Interneurons. — PubMed · 2025 · Journal Article
- Phosphodiesterase 2A as a Therapeutic Target for Relieving Mechanical Allodynia and Modulating Microglial Polarization in Neuropathic Pain Models Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Astrocytic Inducible Nitric Oxide Synthase Upregulation Contributes to Chronic Below-Level Neuropathic Pain Following Spinal Cord Injury in Male Rats. — PubMed · 2025 · Journal Article
- Ion-channel mRNA expression alterations in a cervical dorsal horn compression induced novel rabbit model of trigeminal neuropathic pain. — PubMed · 2025 · Journal Article
- Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels. — PubMed · 2025 · Journal Article
- LncRNA 4933431K23Rik modulate microglial phenotype via inhibiting miR-10a-5p in spinal cord injury induced neuropathic pain. — PubMed · 2025 · Journal Article
- Repeated Administrations of Polyphenolic Extracts Prevent Chronic Reflexive and Non-Reflexive Neuropathic Pain Responses by Modulating Gliosis and CCL2-CCR2/CX3CL1-CX3CR1 Signaling in Spinal Cord-Injured Female Mice. — PubMed · 2025 · Journal Article
- Metformin's therapeutic potential in spinal cord injury: a systematic review and meta-analysis on locomotor recovery, neuropathic pain alleviation, and modulation of secondary injury mechanisms. — PubMed · 2025 · Journal Article
- Ivabradine reduces neuropathic pain after spinal cord injury by inhibiting excitatory synaptic transmission in the spinal dorsal horn. — PubMed · 2025 · Journal Article
- Emergent epileptiform activity in spinal sensory circuits drives ectopic bursting in afferent axons and sensory dysfunction after cord injury. — PubMed · 2025 · Journal Article
- Formoterol alters chemokine expression and ameliorates pain behaviors after moderate spinal cord injury in female mice. — PubMed · 2025 · Journal Article
- Valacyclovir and Acyclovir Are Substrates of the Guanine Deaminase Cytosolic PSD-95 Interactor (Cypin). — PubMed · 2025 · Journal Article
- Differential Neuronal Activation of Nociceptive Pathways in Neuropathic Pain After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- TrkB Agonist (7,8-DHF)-Induced Responses in Dorsal Root Ganglia Neurons Are Decreased after Spinal Cord Injury: Implication for Peripheral Pain Mechanisms. — PubMed · 2025 · Journal Article
- Administration of anti-GFAP antibodies increases CGRP expression and increases pain hypersensitivity in spinal cord injured animals. — PubMed · 2025 · Journal Article
- Discriminating fingerprints of chronic neuropathic pain following spinal cord injury using artificial neural networks and mass spectrometry analysis of female mice serum. — PubMed · 2024 · Journal Article
- Mirtazapine Improves Locomotor Activity and Attenuates Neuropathic Pain Following Spinal Cord Injury in Rats via Neuroinflammation Modulation. — PubMed · 2024 · Journal Article
- Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache. — PubMed · 2024 · Journal Article
- Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury. — PubMed · 2024 · Journal Article
- Corticothalamic input derived from corticospinal neurons contributes to chronic neuropathic pain after spinal cord injury. — PubMed · 2024 · Journal Article
- The effect of intra spinal administration of cerium oxide nanoparticles on central pain mechanism: An experimental study. — PubMed · 2024 · Journal Article
- Transcriptomic Profiling of Primary Microglia: Effects of miR-19a-3p and miR-19b-3p on Microglia Activation. — PubMed · 2024 · Journal Article
- Combined use of CLP290 and bumetanide alleviates neuropathic pain and its mechanism after spinal cord injury in rats. — PubMed · 2024 · Journal Article
- Mechanism of gabapentinoid potentiation of opioid effects on cyclic AMP signaling in neuropathic pain. — PubMed · 2024 · Journal Article
- TRPM7 Mediates Neuropathic Pain by Activating mTOR Signaling in Astrocytes after Spinal Cord Injury in Rats. — PubMed · 2024 · Journal Article
- Chronic Spinal Cord Injury Increases Spontaneous Intraspinal Neural Transmission and Spike Train Variability. — PubMed · 2024 · Journal Article
- Nonlinear Firing Dynamics in Spinal Interneurons May Delineate the Presence or Absence of Spinal Cord Injury-related Neuropathic Pain. — PubMed · 2024 · Journal Article
- Osteopontin Promotes Angiogenesis in the Spinal Cord and Exerts a Protective Role Against Motor Function Impairment and Neuropathic Pain After Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Chemogenetic Attenuation of Acute Nociceptive Signaling Enhances Functional Outcomes Following Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Effects of dim light at night in C57BL/6 J mice on recovery after spinal cord injury. — PubMed · 2024 · Journal Article
- Myeloid Cell Association with Spinal Cord Injury-Induced Neuropathic Pain and Depressive-like Behaviors in LysM-eGFP Mice. — PubMed · 2024 · Journal Article
- Positive Correlation Between Motor Function and Neuropathic Pain-Like Behaviors After Spinal Cord Injury: A Longitudinal Study of Mice. — PubMed · 2024 · Journal Article
- Dissecting Genetic Mechanisms of Differential Locomotion, Depression, and Allodynia after Spinal Cord Injury in Three Mouse Strains. — PubMed · 2024 · Journal Article
- Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway. — PubMed · 2024 · Journal Article
- Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model. — PubMed · 2024 · Journal Article
- Tropisetron attenuates neuroinflammation and chronic neuropathic pain via α7nAChR activation in the spinal cord in rats. — PubMed · 2024 · Journal Article
- Cypin Inhibition as a Therapeutic Approach to Treat Spinal Cord Injury-Induced Mechanical Pain. — PubMed · 2024 · Journal Article
- Combined effect of Cerium oxide nanoparticles loaded scaffold and photobiomodulation therapy on pain and neuronal regeneration following spinal cord injury: an experimental study. — PubMed · 2024 · Journal Article
- Autophagy exerts a protective role in cervical spinal cord injury by microglia inhibition through the nuclear factor kappa-B pathway. — PubMed · 2024 · Journal Article
- Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury. — PubMed · 2024 · Journal Article
- IL-6/JAK2/STAT3 axis mediates neuropathic pain by regulating astrocyte and microglia activation after spinal cord injury. — PubMed · 2023 · Journal Article
- Photobiomodulation reduces neuropathic pain after spinal cord injury by downregulating CXCL10 expression. — PubMed · 2023 · Journal Article
- Relating Spinal Injury-Induced Neuropathic Pain and Spontaneous Afferent Activity to Sleep and Respiratory Dysfunction. — PubMed · 2023 · Journal Article
- Resolvin D2 activates anti-inflammatory microglia via restoring autophagy flux and alleviate neuropathic pain following spinal cord injury in rats. — PubMed · 2023 · Journal Article
- Chitosan biomaterial enhances the effect of OECs on the inhibition of sciatic nerve injury-induced neuropathic pain. — PubMed · 2023 · Journal Article
- Evaluation of photobiomodulation therapy (117 and 90s) on pain, regeneration, and epigenetic factors (HDAC 2, DNMT3a) expression following spinal cord injury in a rat model. — PubMed · 2023 · Journal Article
- Increased astrocytic GLT-1 expression in tripartite synapses is associated with SCI-induced hyperreflexia. — PubMed · 2023 · Journal Article
- ST2-Conditioned Medium Fosters Dorsal Horn Cell Excitability and Synaptic Transmission in Cultured Mouse Spinal Cord. — PubMed · 2023 · Journal Article
- Inhibition of T-Type Calcium Channels With TTA-P2 Reduces Chronic Neuropathic Pain Following Spinal Cord Injury in Rats. — PubMed · 2023 · Journal Article
- Minocycline relieves neuropathic pain in rats with spinal cord injury via activation of autophagy and suppression of PI3K/Akt/mTOR pathway. — PubMed · 2023 · Journal Article
- Rolipram-loaded PgP nanoparticle reduces secondary injury and enhances motor function recovery in a rat moderate contusion SCI model. — PubMed · 2023 · Journal Article
- Hydralazine Promotes Central Nervous System Recovery after Spinal Cord Injury by Suppressing Oxidative Stress and Inflammation through Macrophage Regulation. — PubMed · 2023 · Journal Article The source marks this record as retracted.
- Suberoylanilide Hydroxamic Acid Ameliorates Pain Sensitization in Central Neuropathic Pain After Spinal Cord Injury via the HDAC5/NEDD4/SCN9A Axis. — PubMed · 2023 · Journal Article
- Suppression of microglial Ccl2 reduces neuropathic pain associated with chronic spinal compression. — PubMed · 2023 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | asked, and it answered | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 2 · accumulated records across collection walks 176 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 2050358 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 2439 · accumulated records across collection walks 2439 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuropathic pain" OR "central pain") - Crossref
spinal cord injury neuropathic pain central pain - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuralgia"[MeSH Terms] OR "Chronic Pain"[MeSH Terms] OR "neuropathic pain"[Title/Abstract] OR "central pain"[Title/Abstract])