A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Circuit reconstruction of newborn neurons after spinal cord injury in adult rats via an NT3-chitosan scaffold. — PubMed · 2023 · Journal Article
- Depletion of SASH1, an astrocyte differentiation-related gene, contributes to functional recovery in spinal cord injury. — PubMed · 2023 · Journal Article
- Spinal Canal and Spinal Cord in Rat Continue to Grow Even after Sexual Maturation: Anatomical Study and Molecular Proposition. — PubMed · 2022 · Journal Article
- Apigenin inhibits fibrous scar formation after acute spinal cord injury through TGFβ/SMADs signaling pathway. — PubMed · 2022 · Journal Article
- Bone Marrow Mesenchymal Stem Cell Exosome Attenuates Inflammasome-Related Pyroptosis via Delivering circ_003564 to Improve the Recovery of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin. — PubMed · 2022 · Journal Article
- Research on Polycaprolactone-Gelatin Composite Scaffolds Carrying Nerve Growth Factor for the Repair of Spinal Cord Injury. — PubMed · 2022 · Journal Article The source marks this record as retracted.
- 7,8-Dihydroxyflavone accelerates recovery of Brown-Sequard syndrome in adult female rats with spinal cord lateral hemisection. — PubMed · 2022 · Journal Article
- NPC transplantation rescues sci-driven cAMP/EPAC2 alterations, leading to neuroprotection and microglial modulation. — PubMed · 2022 · Journal Article
- Exosomes derived from NGF-overexpressing bone marrow mesenchymal stem cell sheet promote spinal cord injury repair in a mouse model. — PubMed · 2022 · Journal Article
- Insulin-Like Growth Factor-1 Enhances Motoneuron Survival and Inhibits Neuroinflammation After Spinal Cord Transection in Zebrafish. — PubMed · 2022 · Journal Article
- Fecal Microbiota Transplantation Exerts Neuroprotective Effects in a Mouse Spinal Cord Injury Model by Modulating the Microenvironment at the Lesion Site. — PubMed · 2022 · Journal Article
- Body Weight-Supported Treadmill Training Ameliorates Motoneuronal Hyperexcitability by Increasing GAD-65/67 and KCC2 Expression via TrkB Signaling in Rats with Incomplete Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Nerve growth factor-mediated Na(+) channel plasticity of bladder afferent neurons in mice with spinal cord injury. — PubMed · 2022 · Journal Article
- NT3 treatment alters spinal cord injury-induced changes in the gray matter volume of rhesus monkey cortex. — PubMed · 2022 · Journal Article
- Peptide OM-LV20 promotes structural and functional recovery of spinal cord injury in rats. — PubMed · 2022 · Journal Article
- hUC-MSC-mediated recovery of subacute spinal cord injury through enhancing the pivotal subunits β3 and γ2 of the GABA(A) receptor. — PubMed · 2022 · Journal Article
- Application of a New Gene-Cell Construct Based on the Olfactory Mucosa Escheating Cells Transduced with an Adenoviral Vector Encoding Mature BDNF in the Therapy of Spinal Cord Cysts. — PubMed · 2022 · Journal Article
- Activation of Three Major Signaling Pathways After Endurance Training and Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Nerve Growth Factor-Laden Anisotropic Silk Nanofiber Hydrogels to Regulate Neuronal/Astroglial Differentiation for Scarless Spinal Cord Repair. — PubMed · 2022 · Journal Article
- The effect of Iridoids effective fraction of Valeriana jatamansi Jones on movement function in rats after acute cord injury and the related mechanism. — PubMed · 2022 · Journal Article
- New Therapy for Spinal Cord Injury: Autologous Genetically-Enriched Leucoconcentrate Integrated with Epidural Electrical Stimulation. — PubMed · 2022 · Journal Article
- Cotransplantation with RADA16-PRG-Self-Assembled Nanopeptide Scaffolds, Bone Mesenchymal Stem Cells and Brain-Derived Neurotrophic Factor-Adeno-Associated Virus Promote Functional Repair After Acute Spinal Cord Injury in Rats. — PubMed · 2022 · Journal Article
- Homeodomain Interacting Protein Kinase 2-Modified Rat Spinal Astrocytes Affect Neurofunctional Recovery After Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Hypoxic preconditioning neural stem cell transplantation promotes spinal cord injury in rats by affecting transmembrane immunoglobulin domain-containing. — PubMed · 2022 · Journal Article
- Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine. — PubMed · 2022 · Journal Article
- Availability of neuregulin-1beta1 protects neurons in spinal cord injury and against glutamate toxicity through caspase dependent and independent mechanisms. — PubMed · 2021 · Journal Article
- Treadmill training based on the overload principle promotes locomotor recovery in a mouse model of chronic spinal cord injury. — PubMed · 2021 · Journal Article
- Changes in depressive-like behaviors induced by spinal cord injury based on the hypothalamic-pituitary-adrenal axis and hippocampal neurogenesis. — PubMed · 2021 · Journal Article
- [Effect of electroacupuncture on urodynamics of neurogenic bladder and PACAP/cAMP/PKA signaling pathway in detrusor tissue of rats after suprasacral spinal cord injury]. — PubMed · 2021 · Journal Article
- Resveratrol inhibits inflammation after spinal cord injury via SIRT-1/NF-κB signaling pathway. — PubMed · 2021 · Journal Article
- Thermo-sensitive electroactive hydrogel combined with electrical stimulation for repair of spinal cord injury. — PubMed · 2021 · Journal Article
- Comparisons of Neurotrophic Effects of Mesenchymal Stem Cells Derived from Different Tissues on Chronic Spinal Cord Injury Rats. — PubMed · 2021 · Journal Article
- The thrombin receptor modulates astroglia-neuron trophic coupling and neural repair after spinal cord injury. — PubMed · 2021 · Journal Article
- A Time-Course Study of the Expression Level of Synaptic Plasticity-Associated Genes in Un-Lesioned Spinal Cord and Brain Areas in a Rat Model of Spinal Cord Injury: A Bioinformatic Approach. — PubMed · 2021 · Journal Article
- Sigma 1 receptor agonist cutamesine promotes plasticity of serotonergic boutons in lumbar enlargement in spinal cord injured rats. — PubMed · 2021 · Journal Article
- Interleukin-17A regulates ependymal cell proliferation and functional recovery after spinal cord injury in mice. — PubMed · 2021 · Journal Article
- Intraspinal Administration of Netrin-1 Promotes Locomotor Recovery after Complete Spinal Cord Transection. — PubMed · 2021 · Journal Article
- Nerve growth factor loaded macrophage-derived nanovesicles for inhibiting neuronal apoptosis after spinal cord injury. — PubMed · 2021 · Journal Article
- Up-regulation of miR-338-5p after spinal cord injury enhances the neuronal repair via inhibition of inflammation aggravation and oxidative stress. — PubMed · 2021 · Letter
- miR-21a-5p Promotes Inflammation following Traumatic Spinal Cord Injury through Upregulation of Neurotoxic Reactive Astrocyte (A1) Polarization by Inhibiting the CNTF/STAT3/Nkrf Pathway. — PubMed · 2021 · Journal Article
- Neuroprotective effect of neuregulin-1β on spinal cord ischemia reperfusion injury. — PubMed · 2021 · Journal Article
- Thermosensitive quaternized chitosan hydrogel scaffolds promote neural differentiation in bone marrow mesenchymal stem cells and functional recovery in a rat spinal cord injury model. — PubMed · 2021 · Journal Article
- Time-dependent progression of neurogenic lower urinary tract dysfunction after spinal cord injury in the mouse model. — PubMed · 2021 · Journal Article
- Acute intrathecal BDNF enhances functional recovery after cervical spinal cord injury in rats. — PubMed · 2021 · Journal Article
- A TrkB Antibody Agonist Promotes Plasticity after Cervical Spinal Cord Injury in Adult Rats. — PubMed · 2021 · Journal Article
- Lithium alleviated spinal cord injury (SCI)-induced apoptosis and inflammation in rats via BDNF-AS/miR-9-5p axis. — PubMed · 2021 · Journal Article
- Binary scaffold facilitates in situ regeneration of axons and neurons for complete spinal cord injury repair. — PubMed · 2021 · Journal Article
- Peripheral Nerve-Derived Stem Cell Spheroids Induce Functional Recovery and Repair after Spinal Cord Injury in Rodents. — PubMed · 2021 · Journal Article
- Effects of combination treatment with transcranial magnetic stimulation and bone marrow mesenchymal stem cell transplantation or Raf inhibition on spinal cord injury in rats. — PubMed · 2021 · Journal Article
- Locomotor deficits induced by lumbar muscle inflammation involve spinal microglia and are independent of KCC2 expression in a mouse model of complete spinal transection. — PubMed · 2021 · Journal Article
- Governor Vessel Electro-Acupuncture Promotes the Intrinsic Growth Ability of Spinal Neurons through Activating Calcitonin Gene-Related Peptide/α-Calcium/Calmodulin-Dependent Protein Kinase/Neurotrophin-3 Pathway after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Effects of minocycline on motor function recovery and expression of glial fibrillary acidic protein and brain-derived neurotrophic factor after spinal cord injury in rats. — PubMed · 2021 · Journal Article
- Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p/145-5p-mediated NGF/TrkA signaling pathway in rats. — PubMed · 2021 · Journal Article
- Nanoparticle-Based Estrogen Delivery to Spinal Cord Injury Site Reduces Local Parenchymal Destruction and Improves Functional Recovery. — PubMed · 2021 · Journal Article
- Neuregulin-1 converts reactive astrocytes toward oligodendrocyte lineage cells via upregulating the PI3K-AKT-mTOR pathway to repair spinal cord injury. — PubMed · 2021 · Journal Article
- The lncRNA Ftx/miR-382-5p/Nrg1 axis improves the inflammation response of microglia and spinal cord injury repair. — PubMed · 2021 · Journal Article
- Water treadmill training protects the integrity of the blood-spinal cord barrier following SCI via the BDNF/TrkB-CREB signalling pathway. — PubMed · 2021 · Journal Article
- A combinatorial approach to modulate microenvironment toward regeneration and repair after spinal cord injury in rats. — PubMed · 2021 · Journal Article
- BmK NSPK, a Potent Potassium Channel Inhibitor from Scorpion Buthus martensii Karsch, Promotes Neurite Outgrowth via NGF/TrkA Signaling Pathway. — PubMed · 2021 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 5 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1558014 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 1726 · this programme has 1726 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])