A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Dynamics of biomarkers across the stages of traumatic spinal cord injury - implications for neural plasticity and repair. — PubMed · 2021 · Journal Article
- MiR-124 improves spinal cord injury in rats by activating the Wnt/β-catenin signaling pathway. — PubMed · 2020 · Letter
- Therapeutic effect of metformin on inflammation and apoptosis after spinal cord injury in rats through the Wnt/β-catenin signaling pathway. — PubMed · 2020 · Journal Article
- Delivery of injectable thermo-sensitive hydrogel releasing nerve growth factor for spinal cord regeneration in rat animal model. — PubMed · 2020 · Journal Article
- Intrathecal Delivery of BDNF Into the Lumbar Cistern Re-Engages Locomotor Stepping After Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Effect of Simultaneous Combined Treadmill Training and Magnetic Stimulation on Spasticity and Gait Impairments after Cervical Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Deep Brain Stimulation Improves Motor Function in Rats with Spinal Cord Injury by Increasing Synaptic Plasticity. — PubMed · 2020 · Journal Article
- Neuroprotective effect of gastrodin in methamphetamine-induced apoptosis through regulating cAMP/PKA/CREB pathway in cortical neuron. — PubMed · 2020 · Journal Article
- Reactive astrocytes increase expression of proNGF in the mouse model of contused spinal cord injury. — PubMed · 2020 · Journal Article
- Ginsenoside Rg1-induced activation of astrocytes promotes functional recovery via the PI3K/Akt signaling pathway following spinal cord injury. — PubMed · 2020 · Journal Article
- Thermosensitive heparin-poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury. — PubMed · 2020 · Journal Article
- Molecular and histologic outcomes following spinal cord injury in spiny mice, Acomys cahirinus. — PubMed · 2020 · Journal Article
- Immunization with neural-derived peptides increases neurogenesis in rats with chronic spinal cord injury. — PubMed · 2020 · Journal Article
- Low-energy extracorporeal shock wave therapy promotes BDNF expression and improves functional recovery after spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. — PubMed · 2020 · Journal Article
- Production and evaluation of biosynthesized cellulose tubes as promising nerve guides for spinal cord injury treatment. — PubMed · 2020 · Journal Article
- The early, long-term inhibition of brain-derived neurotrophic factor improves voiding, and storage dysfunctions in mice with spinal cord injury. — PubMed · 2020 · Journal Article
- Neuroprotection of netrin-1 on neurological recovery via Wnt/β-catenin signaling pathway after spinal cord injury. — PubMed · 2020 · Journal Article
- Protective effect of brain-derived neurotrophic factor and neurotrophin-3 overexpression by adipose-derived stem cells combined with silk fibroin/chitosan scaffold in spinal cord injury. — PubMed · 2020 · Journal Article
- The combined effect of granulocyte-colony stimulating factor (G-CSF) treatment and exercise in rats with spinal cord injury. — PubMed · 2020 · Journal Article
- Repairing and Analgesic Effects of Umbilical Cord Mesenchymal Stem Cell Transplantation in Mice with Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Rehabilitation Decreases Spasticity by Restoring Chloride Homeostasis through the Brain-Derived Neurotrophic Factor-KCC2 Pathway after Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Effect of NT-3 on repair of spinal cord injury through the MAPK signaling pathway. — PubMed · 2020 · Journal Article
- Human gingival derived neuronal cells in the optimized caffeic acid hydrogel for hemitransection spinal cord injury model. — PubMed · 2020 · Journal Article
- Neurotrophin-3-Loaded Multichannel Nanofibrous Scaffolds Promoted Anti-Inflammation, Neuronal Differentiation, and Functional Recovery after Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Combined with anti-Nogo-A antibody treatment, BDNF did not compensate the extra deleterious motor effect caused by large size cervical cord hemisection in adult macaques. — PubMed · 2020 · Journal Article
- Exercise training modulates glutamic acid decarboxylase-65/67 expression through TrkB signaling to ameliorate neuropathic pain in rats with spinal cord injury. — PubMed · 2020 · Journal Article
- FBXW7alpha Promotes the Recovery of Traumatic Spinal Cord. — PubMed · 2020 · Journal Article
- Investigating the synergic effects of valproic acid and crocin on BDNF and GDNF expression in epidermal neural crest stem cells. — PubMed · 2020 · Comparative Study
- Low-level laser therapy 810-nm up-regulates macrophage secretion of neurotrophic factors via PKA-CREB and promotes neuronal axon regeneration in vitro. — PubMed · 2020 · Journal Article
- Suppression of miR-10a-5p in bone marrow mesenchymal stem cells enhances the therapeutic effect on spinal cord injury via BDNF. — PubMed · 2020 · Journal Article
- AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injury. — PubMed · 2019 · Journal Article
- Graphene oxide-PLGA hybrid nanofibres for the local delivery of IGF-1 and BDNF in spinal cord repair. — PubMed · 2019 · Journal Article
- DNA methylation and behavioral changes induced by neonatal spinal transection. — PubMed · 2019 · Journal Article
- MiR-223-5p inhibitor suppresses microglia inflammation and promotes Nrg-1 in rats of spinal cord injury. — PubMed · 2019 · Journal Article
- Neuroectodermal Stem Cells Grafted into the Injured Spinal Cord Induce Both Axonal Regeneration and Morphological Restoration via Multiple Mechanisms. — PubMed · 2019 · Journal Article
- Pigment Epithelium-Derived Factor Promotes Axon Regeneration and Functional Recovery After Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Therapeutic effects of inhibition of brain-derived neurotrophic factor on voiding dysfunction in mice with spinal cord injury. — PubMed · 2019 · Journal Article
- Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation. — PubMed · 2019 · Journal Article
- Regulation of autophagy in mesenchymal stem cells modulates therapeutic effects on spinal cord injury. — PubMed · 2019 · Journal Article
- Reflex arc recovery after spinal cord dorsal root repair with platelet rich plasma (PRP). — PubMed · 2019 · Journal Article
- Regenerative Effect of Growth Hormone (GH) in the Retina after Kainic Acid Excitotoxic Damage. — PubMed · 2019 · Journal Article
- Overground gait training promotes functional recovery and cortical neuroplasticity in an incomplete spinal cord injury model. — PubMed · 2019 · Journal Article
- Role of the BDNF-TrkB pathway in KCC2 regulation and rehabilitation following neuronal injury: A mini review. — PubMed · 2019 · Journal Article
- Efficient Delivery of Nerve Growth Factors to the Central Nervous System for Neural Regeneration. — PubMed · 2019 · Journal Article
- Pre-Clinical Evaluation of CBD-NT3 Modified Collagen Scaffolds in Completely Spinal Cord Transected Non-Human Primates. — PubMed · 2019 · Journal Article
- Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats. — PubMed · 2019 · Journal Article
- Enhancing the expression of neurotrophic factors in epidermal neural crest stem cells by valproic acid: A potential candidate for combinatorial treatment. — PubMed · 2019 · Journal Article
- Electroacupuncture improves neurogenic bladder dysfunction through activation of NGF/TrkA signaling in a rat model. — PubMed · 2019 · Journal Article
- Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats. — PubMed · 2019 · Journal Article
- Tet1 Overexpression and Decreased DNA Hydroxymethylation Protect Neurons Against Cell Death After Injury by Increasing Expression of Genes Involved in Cell Survival. — PubMed · 2019 · Journal Article
- The effect of lithium chloride on BDNF, NT3, and their receptor mRNA levels in the spinal contusion rat models. — PubMed · 2019 · Journal Article
- Investigating Nrg1 Signaling in the Regenerating Axolotl Spinal Cord Using Multiplexed FISH. — PubMed · 2019 · Journal Article
- MiR-29 regulates retinopathy in diabetic mice via the AMPK signaling pathway. — PubMed · 2019 · Journal Article
- Bone marrow mesenchymal stem cells stimulated with low-intensity pulsed ultrasound: Better choice of transplantation treatment for spinal cord injury: Treatment for SCI by LIPUS-BMSCs transplantation. — PubMed · 2019 · Journal Article
- Hyperbaric oxygen improves functional recovery of rats after spinal cord injury via activating stromal cell-derived factor-1/CXC chemokine receptor 4 axis and promoting brain-derived neurothrophic factor expression. — PubMed · 2019 · Journal Article
- Bone Marrow-Derived Monocytes Drive the Inflammatory Microenvironment in Local and Remote Regions after Thoracic Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Abdominal Aortic Transplantation of Bone Marrow Mesenchymal Stem Cells Regulates the Expression of Ciliary Neurotrophic Factor and Inflammatory Cytokines in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury. — PubMed · 2019 · Journal Article
- Intramuscular Injection of Adenoassociated Virus Encoding Human Neurotrophic Factor 3 and Exercise Intervention Contribute to Reduce Spasms after Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Locomotor Training Increases Synaptic Structure With High NGL-2 Expression After Spinal Cord Hemisection. — PubMed · 2019 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 5 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1558014 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 1726 · this programme has 1726 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])