A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Experimental subacute spinal cord compression: correlation of serial S100B and NSE serum measurements, histopathological changes, and outcome. — PubMed · 2011 · Journal Article
- Treadmill step training-induced adaptive muscular plasticity in a chronic paraplegia model. — PubMed · 2011 · Journal Article
- Expression of tyrosine kinase receptor C in the segments of the spinal cord and the cerebral cortex after cord transection in adult rats. — PubMed · 2011 · Journal Article
- Neuropathic pain- and glial derived neurotrophic factor-associated regulation of cadherins in spinal circuits of the dorsal horn. — PubMed · 2011 · Journal Article
- Initial phase of neuropathic pain within a few hours after nerve injury in mice. — PubMed · 2011 · Comparative Study
- Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord. — PubMed · 2011 · Journal Article
- Acid fibroblast growth factor and peripheral nerve grafts regulate Th2 cytokine expression, macrophage activation, polyamine synthesis, and neurotrophin expression in transected rat spinal cords. — PubMed · 2011 · Journal Article
- Activity-dependent increase in neurotrophic factors is associated with an enhanced modulation of spinal reflexes after spinal cord injury. — PubMed · 2011 · Journal Article
- Neurotrophin 3 improves delayed reconstruction of sensory pathways after cervical dorsal root injury. — PubMed · 2011 · Journal Article
- Sustained delivery of activated Rho GTPases and BDNF promotes axon growth in CSPG-rich regions following spinal cord injury. — PubMed · 2011 · Journal Article
- Simvastatin treatment improves functional recovery after experimental spinal cord injury by upregulating the expression of BDNF and GDNF. — PubMed · 2011 · Journal Article
- Anti-neuroinflammatory and neurotrophic effects of combined therapy with annexin II and Reg-2 on injured spinal cord. — PubMed · 2011 · Journal Article
- Comparison of canine umbilical cord blood-derived mesenchymal stem cell transplantation times: involvement of astrogliosis, inflammation, intracellular actin cytoskeleton pathways, and neurotrophin-3. — PubMed · 2011 · Journal Article
- Effects of a single dose of methylprednisolone versus three doses of rosiglitazone on nerve growth factor levels after spinal cord injury. — PubMed · 2011 · Journal Article
- Electro-acupuncture promotes differentiation of mesenchymal stem cells, regeneration of nerve fibers and partial functional recovery after spinal cord injury. — PubMed · 2011 · Journal Article
- Ghrelin alleviates spinal cord injury in rats via its anti-inflammatory effects. — PubMed · 2011 · Journal Article
- Optimal time point for neuronal generation of transplanted neural progenitor cells in injured spinal cord following root avulsion. — PubMed · 2011 · Journal Article
- The neuroprotective effects of Reg-2 following spinal cord transection injury. — PubMed · 2011 · Comparative Study
- Treatment of rat spinal cord injury with the neurotrophic factor albumin-oleic acid: translational application for paralysis, spasticity and pain. — PubMed · 2011 · Journal Article
- 2-Decenoic acid ethyl ester, a derivative of unsaturated medium-chain fatty acids, facilitates functional recovery of locomotor activity after spinal cord injury. — PubMed · 2010 · Journal Article
- Implantation of adult bone marrow-derived mesenchymal stem cells transfected with the neurotrophin-3 gene and pretreated with retinoic acid in completely transected spinal cord. — PubMed · 2010 · Journal Article
- Functional and histological improvement of the injured spinal cord following transplantation of Schwann cells transfected with NRG1 gene. — PubMed · 2010 · Journal Article
- Neurotrophic factors improve muscle reinnervation from embryonic neurons. — PubMed · 2010 · Journal Article
- Microglia, corticotropin-releasing hormone, and spinal cord injury. — PubMed · 2010 · News
- Structural neuroplasticity following T5 spinal cord transection: increased cardiac sympathetic innervation density and SPN arborization. — PubMed · 2010 · Journal Article
- Neurite outgrowth from PC12 cells is enhanced by an inhibitor of mechanical channels. — PubMed · 2010 · Journal Article
- Regeneration of long-tract axons through sites of spinal cord injury using templated agarose scaffolds. — PubMed · 2010 · Journal Article
- Combined genetic attenuation of myelin and semaphorin-mediated growth inhibition is insufficient to promote serotonergic axon regeneration. — PubMed · 2010 · Journal Article
- Inhibition of apoptotic cell death by ghrelin improves functional recovery after spinal cord injury. — PubMed · 2010 · Evaluation Study
- [Preliminary study on effects of human brain-derived neurotrophic factor gene-modified bone marrow mesenchymal stem cells by intravenous transplantation on structure and function of rat injured spinal cord]. — PubMed · 2010 · English Abstract
- Local and remote growth factor effects after primate spinal cord injury. — PubMed · 2010 · Journal Article
- Hydrogen-rich saline protects against spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Attenuating experimental spinal cord injury by hyperbaric oxygen: stimulating production of vasculoendothelial and glial cell line-derived neurotrophic growth factors and interleukin-10. — PubMed · 2010 · Journal Article
- Cerebrolysin reduces blood-cerebrospinal fluid barrier permeability change, brain pathology, and functional deficits following traumatic brain injury in the rat. — PubMed · 2010 · Journal Article
- ProBDNF inhibits infiltration of ED1+ macrophages after spinal cord injury. — PubMed · 2010 · Journal Article
- Promoting directional axon growth from neural progenitors grafted into the injured spinal cord. — PubMed · 2010 · Journal Article
- The hematopoietic factor granulocyte-colony stimulating factor improves outcome in experimental spinal cord injury. — PubMed · 2010 · Journal Article
- Differential regulation of dendritic plasticity by neurotrophins following deafferentation of the adult spinal cord is independent of p75(NTR). — PubMed · 2010 · Journal Article
- Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation. — PubMed · 2010 · Journal Article
- Ginsenoside Rg1 promotes proliferation and neurotrophin expression of olfactory ensheathing cells. — PubMed · 2010 · Journal Article
- Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury. — PubMed · 2010 · Journal Article
- [Effects of Yiqi Huayu Decoction on brain-derived neurotrophic factor expression in rats with lumbar nerve root injury]. — PubMed · 2010 · English Abstract
- Quercetin administration after spinal cord trauma changes S-100 levels. — PubMed · 2010 · Journal Article
- Targeted retrograde gene delivery of brain-derived neurotrophic factor suppresses apoptosis of neurons and oligodendroglia after spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Transplantation of ciliary neurotrophic factor-expressing adult oligodendrocyte precursor cells promotes remyelination and functional recovery after spinal cord injury. — PubMed · 2010 · Journal Article
- Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injury. — PubMed · 2010 · Journal Article
- Stem cells in the adult rat spinal cord: plasticity after injury and treadmill training exercise. — PubMed · 2010 · Journal Article
- Exercise exerts neuroprotective effects on Parkinson's disease model of rats. — PubMed · 2010 · Journal Article
- Effect of neurotrophin-3 genetically modified olfactory ensheathing cells transplantation on spinal cord injury. — PubMed · 2010 · Journal Article
- Selected combination of neurotrophins potentiate neuroprotection and functional recovery following spinal cord injury in the rat. — PubMed · 2010 · Journal Article
- Survival of neurally induced mesenchymal cells may determine degree of motor recovery in injured spinal cord rats. — PubMed · 2010 · Journal Article
- Exercise-induced motor improvement after complete spinal cord transection and its relation to expression of brain-derived neurotrophic factor and presynaptic markers. — PubMed · 2009 · Journal Article
- Guiding regenerating axons to their brainstem targets. — PubMed · 2009 · News
- Muscle-conditioned media and cAMP promote survival and neurite outgrowth of adult spinal cord motor neurons. — PubMed · 2009 · Journal Article
- [The repair of acute spinal cord injury in rats by olfactory ensheathing cells graft modified by glia cell line-derived neurotrophic factor gene in combination with the injection of monoclonal antibody IN-1]. — PubMed · 2009 · English Abstract
- Combining peripheral nerve grafts and chondroitinase promotes functional axonal regeneration in the chronically injured spinal cord. — PubMed · 2009 · Journal Article
- Timing in the absence of supraspinal input II: regularly spaced stimulation induces a lasting alteration in spinal function that depends on the NMDA receptor, BDNF release, and protein synthesis. — PubMed · 2009 · Comparative Study
- Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury. — PubMed · 2009 · Journal Article
- A comparison of autologous and allogenic bone marrow-derived mesenchymal stem cell transplantation in canine spinal cord injury. — PubMed · 2009 · Journal Article
- Neurotrophic factor-expressing mesenchymal stem cells survive transplantation into the contused spinal cord without differentiating into neural cells. — PubMed · 2009 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 5 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1558014 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 1726 · this programme has 1726 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])