A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Preconditioning selective ventral root injury promotes plasticity of ascending sensory neurons in the injured spinal cord of adult rats--possible roles of brain-derived neurotrophic factor, TrkB and p75 neurotrophin receptor. — PubMed · 2009 · Journal Article
- Serial changes in bladder, locomotion, and levels of neurotrophic factors in rats with spinal cord contusion. — PubMed · 2009 · Journal Article
- Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. — PubMed · 2009 · Journal Article
- Environmental factors involved in axonal regeneration following spinal cord transection in rats. — PubMed · 2009 · Journal Article
- Recombinant DNA vaccine against inhibition of neurite outgrowth promotes functional recovery associated with endogeous NGF expression in spinal cord hemisected adult rats. — PubMed · 2009 · Journal Article
- Reconnecting injured nerves. — PubMed · 2009 · Comment
- Role of Neurotrophin 3 in spinal neuroplasticity in rats subjected to cord transection. — PubMed · 2009 · Journal Article
- Comparison of adult neurospheres derived from different origins for treatment of rat spinal cord injury. — PubMed · 2009 · Journal Article
- HSV-mediated transfer of artemin overcomes myelin inhibition to improve outcome after spinal cord injury. — PubMed · 2009 · Journal Article
- Muscle injection of AAV-NT3 promotes anatomical reorganization of CST axons and improves behavioral outcome following SCI. — PubMed · 2009 · Journal Article
- Pre-differentiated embryonic stem cells promote neuronal regeneration by cross-coupling of BDNF and IL-6 signaling pathways in the host tissue. — PubMed · 2009 · Journal Article
- Combination of microsurgery and gene therapy for spinal dorsal root injury repair. — PubMed · 2009 · Journal Article
- Postinjury niches induce temporal shifts in progenitor fates to direct lesion repair after spinal cord injury. — PubMed · 2009 · Journal Article
- Activation of dendritic-like cells and neural stem/progenitor cells in injured spinal cord by GM-CSF. — PubMed · 2009 · Journal Article
- [Endogenous BDNF promote regeneration of injured nervous system]. — PubMed · 2009 · English Abstract
- [Expression of ciliary neurotrophic factor mRNA in spinal cords of adult rats with transection injury]. — PubMed · 2009 · English Abstract
- Forced exercise as a rehabilitation strategy after unilateral cervical spinal cord contusion injury. — PubMed · 2009 · Journal Article
- Paraplegia increased cardiac NGF content, sympathetic tonus, and the susceptibility to ischemia-induced ventricular tachycardia in conscious rats. — PubMed · 2009 · Journal Article
- Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympathetic neurons. — PubMed · 2009 · Journal Article
- Regeneration of spinal cord with cell and gene therapy. — PubMed · 2009 · Comparative Study
- Electro-acupuncture promotes survival, differentiation of the bone marrow mesenchymal stem cells as well as functional recovery in the spinal cord-transected rats. — PubMed · 2009 · Comparative Study
- Spinal cord compression injury in adult rats initiates changes in dorsal horn remodeling that may correlate with development of neuropathic pain. — PubMed · 2009 · Journal Article
- Early exercise in spinal cord injured rats induces allodynia through TrkB signaling. — PubMed · 2009 · Journal Article
- Induction of bone marrow stromal cells into cholinergic-like cells by nerve growth factor. — PubMed · 2009 · Journal Article
- Acute spinal cord injury reduces brain derived neurotrohic factor expression in rat hippocampus. — PubMed · 2009 · Journal Article
- Absence of endogenous interleukin-10 enhances secondary inflammatory process after spinal cord compression injury in mice. — PubMed · 2009 · Journal Article
- Lithium enhances the neuronal differentiation of neural progenitor cells in vitro and after transplantation into the avulsed ventral horn of adult rats through the secretion of brain-derived neurotrophic factor. — PubMed · 2009 · Journal Article
- Modularity of endpoint force patterns evoked using intraspinal microstimulation in treadmill trained and/or neurotrophin-treated chronic spinal cats. — PubMed · 2009 · Journal Article
- Neurotrophic factor treatment after spinal root avulsion injury. — PubMed · 2009 · Journal Article
- Roles of platelet-derived growth factor-B expression in the ventral horn and motor cortex in the spinal cord-hemisected rhesus monkey. — PubMed · 2009 · Journal Article
- Electroacupuncture induced spinal plasticity is linked to multiple gene expressions in dorsal root deafferented rats. — PubMed · 2009 · Journal Article
- NG2 cell response in the CNP-EGFP mouse after contusive spinal cord injury. — PubMed · 2009 · Journal Article
- Cotransplantation of mouse embryonic stem cells and bone marrow stromal cells following spinal cord injury suppresses tumor development. — PubMed · 2009 · Journal Article
- [Effect of olfactory ensheathing cells on growth of spinal cord neurons and its protective effect on neurons after injury in vitro]. — PubMed · 2009 · Journal Article
- Glial cell line-derived neurotrophic factor added to a sciatic nerve fragment grafted in a spinal cord gap ameliorates motor impairments in rats and increases local axonal growth. — PubMed · 2009 · Journal Article
- In vitro and in vivo characterization of neurally modified mesenchymal stem cells induced by epigenetic modifiers and neural stem cell environment. — PubMed · 2008 · Journal Article
- Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury. — PubMed · 2008 · Journal Article
- Temporal changes in the level of neurotrophins in the spinal cord and associated precentral gyrus following spinal hemisection in adult Rhesus monkeys. — PubMed · 2008 · Journal Article
- S100beta and fibroblast growth factor-2 are present in cultured Schwann cells and may exert paracrine actions on the peripheral nerve injury. — PubMed · 2008 · Journal Article
- The role of vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide in the neural pathways controlling the lower urinary tract. — PubMed · 2008 · Journal Article
- Training improves the electrophysiological properties of lumbar neurons and locomotion after thoracic spinal cord injury in rats. — PubMed · 2008 · Journal Article
- Undesired effects of a combinatorial treatment for spinal cord injury--transplantation of olfactory ensheathing cells and BDNF infusion to the red nucleus. — PubMed · 2008 · Journal Article
- Brain-derived neurotrophic factor suppresses anoikis-induced death of Schwann cells. — PubMed · 2008 · Journal Article
- Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury. — PubMed · 2008 · Journal Article
- FK1706, a novel non-immunosuppressant neurophilin ligand, ameliorates motor dysfunction following spinal cord injury through its neuroregenerative action. — PubMed · 2008 · Journal Article
- A novel cell-based therapy for contusion spinal cord injury using GDNF-delivering NIH3T3 cells with dual reporter genes monitored by molecular imaging. — PubMed · 2008 · Journal Article
- Dietary restriction started after spinal cord injury improves functional recovery. — PubMed · 2008 · Journal Article
- Involvement of acidic fibroblast growth factor in spinal cord injury repair processes revealed by a proteomics approach. — PubMed · 2008 · Journal Article
- Gene expression alterations of neurotrophins, their receptors and prohormone convertases in a rat model of spinal cord contusion. — PubMed · 2008 · Journal Article
- Microdialysis in central nervous system disorders and their treatment. — PubMed · 2008 · Journal Article
- Functional recovery after spinal cord injury in mice through activation of microglia and dendritic cells after IL-12 administration. — PubMed · 2008 · Journal Article
- Adenovirus-mediated retrograde transfer of neurotrophin-3 gene enhances survival of anterior horn neurons of twy/twy mice with chronic mechanical compression of the spinal cord. — PubMed · 2008 · Comparative Study
- Effects of intrathecal administration of pituitary adenylate cyclase activating polypeptide on lower urinary tract functions in rats with intact or transected spinal cords. — PubMed · 2008 · Comparative Study
- Exogenous administration of glial cell line-derived neurotrophic factor improves recovery after spinal cord injury. — PubMed · 2008 · Journal Article
- Modulation of dendritic spine remodeling in the motor cortex following spinal cord injury: effects of environmental enrichment and combinatorial treatment with transplants and neurotrophin-3. — PubMed · 2008 · Journal Article
- Graft of pre-injured sural nerve promotes regeneration of corticospinal tract and functional recovery in rats with chronic spinal cord injury. — PubMed · 2008 · Journal Article
- Elevation of neuron-specific enolase and S-100beta protein level in experimental acute spinal cord injury. — PubMed · 2008 · Journal Article
- Aspiration of a cervical spinal contusion injury in preparation for delayed peripheral nerve grafting does not impair forelimb behavior or axon regeneration. — PubMed · 2008 · Journal Article
- Ex vivo non-viral vector-mediated neurotrophin-3 gene transfer to olfactory ensheathing glia: effects on axonal regeneration and functional recovery after implantation in rats with spinal cord injury. — PubMed · 2008 · Journal Article
- Immunofluorescence laser confocal expression and localization study of rat nerve growth guidance cues Netrin-1 and Slit2 after spinal cord injury. — PubMed · 2008 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 5 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1558014 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 1726 · this programme has 1726 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])