A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Peripherally-derived BDNF promotes regeneration of ascending sensory neurons after spinal cord injury. — PubMed · 2008 · Journal Article
- Spinal adenosine A2a receptor activation elicits long-lasting phrenic motor facilitation. — PubMed · 2008 · Journal Article
- Analysis of the intracellular barriers encountered by nonviral gene carriers in a model of spatially controlled delivery to neurons. — PubMed · 2008 · Journal Article
- Immune activation is required for NT-3-induced axonal plasticity in chronic spinal cord injury. — PubMed · 2008 · Journal Article
- Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3. — PubMed · 2008 · Journal Article
- Single exposure to erythropoietin modulates Nerve Growth Factor expression in the spinal cord following traumatic injury: comparison with methylprednisolone. — PubMed · 2008 · Comparative Study
- Mature adipocyte-derived cells, dedifferentiated fat cells (DFAT), promoted functional recovery from spinal cord injury-induced motor dysfunction in rats. — PubMed · 2008 · Journal Article
- Temporal neurotransmitter conditioning restores the functional activity of adult spinal cord neurons in long-term culture. — PubMed · 2008 · Journal Article
- Plasmid-based genetic modification of human bone marrow-derived stromal cells: analysis of cell survival and transgene expression after transplantation in rat spinal cord. — PubMed · 2007 · Journal Article
- Adenovirus vector-mediated ex vivo gene transfer of brain-derived neurotrophic factor to bone marrow stromal cells promotes axonal regeneration after transplantation in completely transected adult rat spinal cord. — PubMed · 2007 · Journal Article
- A select combination of neurotrophins enhances neuroprotection and functional recovery following spinal cord injury. — PubMed · 2007 · Journal Article
- [FGF-2-treatment improves locomotor function via axonal regeneration in the transected rat spinal cord]. — PubMed · 2007 · English Abstract
- Reaching training in rats with spinal cord injury promotes plasticity and task specific recovery. — PubMed · 2007 · Journal Article
- Social and environmental enrichment improves sensory and motor recovery after severe contusive spinal cord injury in the rat. — PubMed · 2007 · Journal Article
- Could neurotrophins replace treadmill training as locomotor therapy following spinal cord injury? Focus on "neurotrophic factors promote and enhance locomotor recovery in untrained spinalized cats". — PubMed · 2007 · Comment
- GDNF selectively promotes regeneration of injury-primed sensory neurons in the lesioned spinal cord. — PubMed · 2007 · Journal Article
- Transduced Schwann cells promote axon growth and myelination after spinal cord injury. — PubMed · 2007 · Journal Article
- Transient growth factor delivery sustains regenerated axons after spinal cord injury. — PubMed · 2007 · Journal Article
- BDNF and learning: Evidence that instrumental training promotes learning within the spinal cord by up-regulating BDNF expression. — PubMed · 2007 · Journal Article
- The p75 neurotrophin receptor is essential for neuronal cell survival and improvement of functional recovery after spinal cord injury. — PubMed · 2007 · Journal Article
- Erythropoietin attenuates neuronal injury and potentiates the expression of pCREB in anterior horn after transient spinal cord ischemia in rats. — PubMed · 2007 · Journal Article
- Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury. — PubMed · 2007 · Journal Article
- Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury. — PubMed · 2007 · Journal Article
- Olfactory ensheathing cells promote migration of Schwann cells by secreted nerve growth factor. — PubMed · 2007 · Journal Article
- Intravenous infusion of dihydroginsenoside Rb1 prevents compressive spinal cord injury and ischemic brain damage through upregulation of VEGF and Bcl-XL. — PubMed · 2007 · Journal Article
- Temporal changes in the expression of some neurotrophins in spinal cord transected adult rats. — PubMed · 2007 · Journal Article
- Endogenous TrkB ligands suppress functional mechanosensory plasticity in the deafferented spinal cord. — PubMed · 2007 · Journal Article
- Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury. — PubMed · 2007 · Journal Article
- Dorsal column sensory axons lack TrkC and are not rescued by local neurotrophin-3 infusions following spinal cord contusion in adult rats. — PubMed · 2007 · Journal Article
- Fibrillation potentials following spinal cord injury: improvement with neurotrophins and exercise. — PubMed · 2007 · Journal Article
- NGF mRNA is expressed in the dorsal root ganglia after spinal cord injury in the rat. — PubMed · 2007 · Journal Article
- Simultaneous application of two neurotrophic factors after spinal cord injury. — PubMed · 2007 · Journal Article
- Delayed transplantation with exogenous neurotrophin administration enhances plasticity of corticofugal projections after spinal cord injury. — PubMed · 2007 · Journal Article
- Rescue of rat anterior horn neurons after spinal cord injury by retrograde transfection of adenovirus vector carrying brain-derived neurotrophic factor gene. — PubMed · 2007 · Journal Article
- Osteopontin-deficient mice exhibit less inflammation, greater tissue damage, and impaired locomotor recovery from spinal cord injury compared with wild-type controls. — PubMed · 2007 · Journal Article
- CNTF promotes the survival and differentiation of adult spinal cord-derived oligodendrocyte precursor cells in vitro but fails to promote remyelination in vivo. — PubMed · 2007 · Journal Article
- Cortical reorganization in NT3-treated experimental spinal cord injury: Functional magnetic resonance imaging. — PubMed · 2007 · Journal Article
- Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. — PubMed · 2007 · Journal Article
- Spinal cord transection enhances afferent-evoked inhibition in lamina II neurons and abolishes BDNF-induced facilitation of their sensory input. — PubMed · 2007 · Journal Article
- Protracted myelin clearance hinders central primary afferent regeneration following dorsal rhizotomy and delayed neurotrophin-3 treatment. — PubMed · 2007 · Journal Article
- Axon regeneration through scars and into sites of chronic spinal cord injury. — PubMed · 2007 · Journal Article
- Combined treatment of neurotrophin-3 gene and neural stem cells is propitious to functional recovery after spinal cord injury. — PubMed · 2007 · Journal Article
- Cotransplant of neural stem cells and NT-3 gene modified Schwann cells promote the recovery of transected spinal cord injury. — PubMed · 2007 · Journal Article
- Effects of single versus combinatorial treatment strategies on beta II-tubulin gene expression in axotomized hamster rubrospinal motoneurons. — PubMed · 2007 · Journal Article
- Gene transfer of insulin-like growth factor-I providing neuroprotection after spinal cord injury in rats. — PubMed · 2007 · Evaluation Study
- Plasma as a scaffold for regeneration of neural precursor cells after transplantation into rats with spinal cord injury. — PubMed · 2007 · Journal Article
- Responses of reactive astrocytes containing S100beta protein and fibroblast growth factor-2 in the border and in the adjacent preserved tissue after a contusion injury of the spinal cord in rats: implications for wound repair and neuroregeneration. — PubMed · 2007 · Journal Article
- Synaptic plasticity modulates the spontaneous recovery of locomotion after spinal cord hemisection. — PubMed · 2007 · Journal Article
- Expression of some neurotrophins in the spinal motoneurons after cord hemisection in adult rats. — PubMed · 2006 · Journal Article
- Neutralization of ciliary neurotrophic factor reduces astrocyte production from transplanted neural stem cells and promotes regeneration of corticospinal tract fibers in spinal cord injury. — PubMed · 2006 · Journal Article
- Positioned to inhibit: netrin-1 and netrin receptor expression after spinal cord injury. — PubMed · 2006 · Journal Article
- Effect of controlled delivery of neurotrophin-3 from fibrin on spinal cord injury in a long term model. — PubMed · 2006 · Comparative Study
- Cell adhesion molecule L1 modulates nerve-growth-factor-induced CGRP-IR fiber sprouting. — PubMed · 2006 · Comparative Study
- IGF-I specifically enhances axon outgrowth of corticospinal motor neurons. — PubMed · 2006 · Journal Article
- Bladder overactivity and hyperexcitability of bladder afferent neurons after intrathecal delivery of nerve growth factor in rats. — PubMed · 2006 · Comparative Study
- An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury. — PubMed · 2006 · Journal Article
- Pain with no gain: allodynia following neural stem cell transplantation in spinal cord injury. — PubMed · 2006 · Journal Article
- Spinal cord regeneration: the action of neurotrophin-3 in spinal cord injury in rats. — PubMed · 2006 · Journal Article
- Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. — PubMed · 2006 · Journal Article
- Neuronal loss and expression of neurotrophic factors in a model of rat chronic compressive spinal cord injury. — PubMed · 2006 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 5 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1558014 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 1726 · this programme has 1726 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])