A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Up-regulation of tyrosine kinase (Trka, Trkb) receptor expression and phosphorylation in lumbosacral dorsal root ganglia after chronic spinal cord (T8-T10) injury. — PubMed · 2002 · Journal Article
- Brain-derived neurotrophic factor applied to the motor cortex promotes sprouting of corticospinal fibers but not regeneration into a peripheral nerve transplant. — PubMed · 2002 · Journal Article
- Accumulation of nerve growth factor protein at both rostral and caudal stumps in the transected rat spinal cord. — PubMed · 2002 · Journal Article
- Brain-derived neurotrophic factor suppresses delayed apoptosis of oligodendrocytes after spinal cord injury in rats. — PubMed · 2002 · Journal Article
- Effect of nerve growth factor on neuronal apoptosis after spinal cord injury in rats. — PubMed · 2002 · Journal Article
- Effects of nerve growth factor on neuronal nitric oxide production after spinal cord injury in rats. — PubMed · 2002 · Journal Article
- Intralesion transplantation of serotonergic precursors enhances locomotor recovery but has no effect on development of chronic central pain following hemisection injury in rats. — PubMed · 2002 · Journal Article
- Neurotrophins reduce degeneration of injured ascending sensory and corticospinal motor axons in adult rat spinal cord. — PubMed · 2002 · Journal Article
- Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy. — PubMed · 2002 · Journal Article
- Promoting axonal regeneration in the central nervous system by enhancing the cell body response to axotomy. — PubMed · 2002 · Journal Article
- Differential electrophysiological effects of brain-derived neurotrophic factor on dorsal horn neurons following chronic spinal cord hemisection injury in the rat. — PubMed · 2002 · Journal Article
- Survival and regeneration of rubrospinal neurons 1 year after spinal cord injury. — PubMed · 2002 · Journal Article
- Expression of neuregulin and ErbB3 and ErbB4 after a traumatic lesion in the ventral funiculus of the spinal cord and in the intact primary olfactory system. — PubMed · 2002 · Comparative Study
- Neurotrophin potentiation of iron-induced spinal cord injury. — PubMed · 2002 · Journal Article
- TrkC overexpression enhances survival and migration of neural stem cell transplants in the rat spinal cord. — PubMed · 2002 · Journal Article
- Spinal cord regeneration: from gene to transplants. — PubMed · 2001 · Journal Article
- Axonal regeneration and functional recovery after complete spinal cord transection in rats by delayed treatment with transplants and neurotrophins. — PubMed · 2001 · Journal Article
- Functional regeneration of chronically injured sensory afferents into adult spinal cord after neurotrophin gene therapy. — PubMed · 2001 · Journal Article
- Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats. — PubMed · 2001 · Journal Article
- Subdural engraftment of serotonergic neurons following spinal hemisection restores spinal serotonin, downregulates serotonin transporter, and increases BDNF tissue content in rat. — PubMed · 2001 · Journal Article
- Acute up-regulation of brain-derived neurotrophic factor expression resulting from experimentally induced injury in the rat spinal cord. — PubMed · 2001 · Journal Article
- Distant microglial and astroglial activation secondary to experimental spinal cord lesion. — PubMed · 2001 · Journal Article
- [Intraspinal implantation of genetically modified myoblasts with brain-derived neurotrophic factor gene in treating spinal cord injury in rats: neurophysiological study]. — PubMed · 2001 · English Abstract
- Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons. — PubMed · 2001 · Journal Article
- A possible role for BDNF, NT-4 and TrkB in the spinal cord and muscle of rat subjected to mechanical overload, bupivacaine injection and axotomy. — PubMed · 2001 · Journal Article
- Pegylated brain-derived neurotrophic factor shows improved distribution into the spinal cord and stimulates locomotor activity and morphological changes after injury. — PubMed · 2001 · Journal Article
- Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid. — PubMed · 2001 · Journal Article
- Neurotrophic factors, cellular bridges and gene therapy for spinal cord injury. — PubMed · 2001 · Journal Article
- [Effect of fetal spinal cord graft with nerve growth factor and nimodipine in secondary injury of spinal cord of adult rat]. — PubMed · 2001 · English Abstract
- Grafting of encapsulated BDNF-producing fibroblasts into the injured spinal cord without immune suppression in adult rats. — PubMed · 2001 · Journal Article
- Neurotrophic and migratory properties of an olfactory ensheathing cell line. — PubMed · 2001 · Journal Article
- Effects of red nucleus ablation and exogenous neurotrophin-3 on corticospinal axon terminal distribution in the adult rat. — PubMed · 2001 · Journal Article
- Intraspinal implants of fibrin glue containing glial cell line-derived neurotrophic factor promote dorsal root regeneration into spinal cord. — PubMed · 2001 · Journal Article
- Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels. — PubMed · 2001 · Journal Article
- Preventive effects of lecithinized superoxide dismutase and methylprednisolone on spinal cord injury in rats: transcriptional regulation of inflammatory and neurotrophic genes. — PubMed · 2001 · Journal Article
- Regulation of Trk receptors following contusion of the rat spinal cord. — PubMed · 2001 · Journal Article
- BDNF abolishes the survival effect of NT-3 in axotomized Clarke neurons of adult rats. — PubMed · 2000 · Journal Article
- Adenovirus-mediated glial cell line-derived neurotrophic factor gene delivery reduces motor neuron injury after transient spinal cord ischemia in rabbits. — PubMed · 2000 · Journal Article
- Brain-derived neurotrophic factor in astrocytes, oligodendrocytes, and microglia/macrophages after spinal cord injury. — PubMed · 2000 · Journal Article
- Effect of brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 on functional recovery and regeneration after spinal cord injury in adult rats. — PubMed · 2000 · Journal Article
- Increase in neurotrophin-3 expression followed by Purkinje cell degeneration in the adult rat cerebellum after spinal cord transection. — PubMed · 2000 · Journal Article
- Up-regulation of glial cell line-derived neurotrophic factor (GDNF) following traumatic spinal cord injury. — PubMed · 2000 · Journal Article
- Changes in truncated trkB and p75 receptor expression in the rat spinal cord following spinal cord hemisection and spinal cord hemisection plus neurotrophin treatment. — PubMed · 2000 · Journal Article
- Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord. — PubMed · 2000 · Journal Article
- Effects of neurotrophic factors on motoneuron survival following axonal injury in newborn rats. — PubMed · 2000 · Journal Article
- Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway. — PubMed · 2000 · Journal Article
- Sequential mRNA expression for immediate early genes, cytokines, and neurotrophins in spinal cord injury. — PubMed · 2000 · Comparative Study
- Leukaemia inhibitory factor is required for normal inflammatory responses to injury in the peripheral and central nervous systems in vivo and is chemotactic for macrophages in vitro. — PubMed · 2000 · Journal Article
- Nerve growth factor in glia and inflammatory cells of the injured rat spinal cord. — PubMed · 2000 · Journal Article
- Survival effects of BDNF and NT-3 on axotomized rubrospinal neurons depend on the temporal pattern of neurotrophin administration. — PubMed · 2000 · Comparative Study
- Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction. — PubMed · 2000 · Journal Article
- Expression of the netrin receptor UNC-5 in lamprey brain: modulation by spinal cord transection. — PubMed · 2000 · Journal Article
- Grafting of genetically modified fibroblasts into the injured spinal cord. — PubMed · 2000 · Journal Article
- Neurotrophic factors attenuate alterations in spinal cord evoked potentials and edema formation following trauma to the rat spinal cord. — PubMed · 2000 · Journal Article
- Neurotrophic factors influence upregulation of constitutive isoform of heme oxygenase and cellular stress response in the spinal cord following trauma. An experimental study using immunohistochemistry in the rat. — PubMed · 2000 · Journal Article
- Topical application of brain derived neurotrophic factor influences upregulation of constitutive isoform of heme oxygenase in the spinal cord following trauma an experimental study using immunohistochemistry in the rat. — PubMed · 2000 · Journal Article
- Induction of glial cell line-derived neurotrophic factor and c-ret porto-oncogene-like immunoreactivity in rabbit spinal cord after transient ischemia. — PubMed · 1999 · Journal Article
- Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. — PubMed · 1999 · Journal Article
- Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1. — PubMed · 1999 · Journal Article
- NT-3 promotes growth of lesioned adult rat sensory axons ascending in the dorsal columns of the spinal cord. — PubMed · 1999 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 5 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1558014 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 1726 · accumulated records across collection walks 1726 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])