A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Neutralizing intraspinal nerve growth factor blocks autonomic dysreflexia caused by spinal cord injury. — PubMed · 1999 · Journal Article
- Peripheral nerve graft and neurotrophic factors enhance neuronal survival and expression of nitric oxide synthase in Clarke's nucleus after hemisection of the spinal cord in adult rat. — PubMed · 1999 · Journal Article
- Basic fibroblast growth factor increases long-term survival of spinal motor neurons and improves respiratory function after experimental spinal cord injury. — PubMed · 1999 · Journal Article
- Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus. — PubMed · 1999 · Journal Article
- Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury. — PubMed · 1999 · Journal Article
- Neuroprotective effects of basic fibroblast growth factor following spinal cord contusion injury in the rat. — PubMed · 1999 · Journal Article
- NGF levels decrease in the spinal cord and dorsal root ganglion after spinal hemisection. — PubMed · 1999 · Journal Article
- Delivering neuroactive molecules from biodegradable microspheres for application in central nervous system disorders. — PubMed · 1999 · Journal Article
- Fetal spinal cord transplants and exogenous neurotrophic support enhance c-Jun expression in mature axotomized neurons after spinal cord injury. — PubMed · 1999 · Journal Article
- Survival of chronically-injured neurons can be prolonged by treatment with neurotrophic factors. — PubMed · 1999 · Journal Article
- Histological investigation of spinal cord lesions in the spinal hyperostotic mouse (twy/twy): morphological changes in anterior horn cells and immunoreactivity to neurotropic factors. — PubMed · 1998 · Comparative Study
- Regeneration in the spinal cord. — PubMed · 1998 · Journal Article
- Trophic factor modulation of c-Jun expression in supraspinal neurons after chronic spinal cord injury. — PubMed · 1998 · Journal Article
- NT-3 delivered by an adenoviral vector induces injured dorsal root axons to regenerate into the spinal cord of adult rats. — PubMed · 1998 · Journal Article
- Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury. — PubMed · 1998 · Journal Article
- Increased ciliary neurotrophic factor expression in reactive astrocytes following spinal cord injury in the rat. — PubMed · 1998 · Journal Article
- NT-3, but not BDNF, prevents atrophy and death of axotomized spinal cord projection neurons. — PubMed · 1998 · Comparative Study
- Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery. — PubMed · 1998 · Journal Article
- Motoneurotrophins derived from limb buds protect the motoneurons in anterior spinal cord after nerve injury and promote nerve regeneration. — PubMed · 1998 · Journal Article
- Nerve growth factor induces process formation in meningeal cells: implications for scar formation in the injured CNS. — PubMed · 1998 · Journal Article
- Local application of collagen containing brain-derived neurotrophic factor decreases the loss of function after spinal cord injury in the adult rat. — PubMed · 1998 · Journal Article
- Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. — PubMed · 1998 · Journal Article
- Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis. — PubMed · 1998 · Journal Article
- Effect of spinal cord injury on the permeability of the blood-brain and blood-spinal cord barriers to the neurotropin PACAP. — PubMed · 1998 · Journal Article
- Effects of macrophage transplantation in the injured adult rat spinal cord: a combined immunocytochemical and biochemical study. — PubMed · 1998 · Journal Article
- Brain derived neurotrophic factor and insulin like growth factor-1 attenuate upregulation of nitric oxide synthase and cell injury following trauma to the spinal cord. An immunohistochemical study in the rat. — PubMed · 1998 · Journal Article
- Transplants and neurotrophic factors prevent atrophy of mature CNS neurons after spinal cord injury. — PubMed · 1998 · Journal Article
- BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration. — PubMed · 1997 · Journal Article
- Effects of neurotransplants and BDNF on the survival and regeneration of injured adult spinal motoneurons. — PubMed · 1997 · Journal Article
- Neurotrophic factors increase axonal growth after spinal cord injury and transplantation in the adult rat. — PubMed · 1997 · Journal Article
- Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells. — PubMed · 1997 · Journal Article
- Spinal cord injury and anti-NGF treatment results in changes in CGRP density and distribution in the dorsal horn in the rat. — PubMed · 1997 · Journal Article
- BDNF is expressed at the crush site after spinal cord lesion in newborn opossum (Monodelphis domestica). — PubMed · 1997 · Journal Article
- Regeneration of hemisectioned spinal cords with and without supporting materials. — PubMed · 1997 · Journal Article
- Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. — PubMed · 1997 · Journal Article
- A non-invasive transport system for GDNF across the blood-brain barrier. — PubMed · 1997 · Journal Article
- [Changes of BDNF mRNA by molecular hybridization during embryonic spinal cord repairing injury of adult rats]. — PubMed · 1997 · English Abstract
- [Expression of neurotrophin and IL-1 beta mRNAs following spinal cord injury and the effects of methylprednisolone treatment]. — PubMed · 1997 · English Abstract
- BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth. — PubMed · 1997 · Comparative Study
- Changes in expression of ciliary neurotrophic factor (CNTF) and CNTF-receptor alpha after spinal cord injury. — PubMed · 1997 · Journal Article
- [Experimental study on nerve growth factor in protecting injured spinal cord]. — PubMed · 1997 · English Abstract
- Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons. — PubMed · 1997 · Journal Article
- Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats. — PubMed · 1996 · Journal Article
- Increased basic fibroblast growth factor expression following contusive spinal cord injury. — PubMed · 1996 · Journal Article
- The effect of the platelet derived wound healing formula and the nerve growth factor on the experimentally injured spinal cord. — PubMed · 1996 · Journal Article
- Ciliary neurotrophic factor stimulates neurite outgrowth from spinal cord neurons. — PubMed · 1996 · Journal Article
- Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury. — PubMed · 1996 · Journal Article
- [Changes of NGF in injured spinal cord following treatment with a single large dose of methylprednisolone sodium succinate]. — PubMed · 1995 · English Abstract
- [Experimental changes in BDNF- and NT-3-like immunoreactivities in the spinal cord following its transection]. — PubMed · 1995 · English Abstract
- Maintaining the neuronal phenotype after injury in the adult CNS. Neurotrophic factors, axonal growth substrates, and gene therapy. — PubMed · 1995 · Journal Article
- BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons. — PubMed · 1995 · Journal Article
- Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats. — PubMed · 1994 · Journal Article
- Bridging a complete transection lesion of adult rat spinal cord with growth factor-treated nitrocellulose implants. — PubMed · 1994 · Journal Article
- Increased basic fibroblast growth factor mRNA following contusive spinal cord injury. — PubMed · 1994 · Journal Article
- Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. — PubMed · 1994 · Journal Article
- Spinal cord repair. A question of making it work. — PubMed · 1994 · Comment
- Response of rubrospinal and corticospinal neurons to injury and neurotrophins. — PubMed · 1994 · Journal Article
- trkC expression in the injured rat spinal cord. — PubMed · 1993 · Journal Article
- Spinal cord transection in adult rats: effects of local infusion of nerve growth factor on the corticospinal tract axons. — PubMed · 1993 · Journal Article
- Potential regulation by trophic factors of low-affinity NGF receptors in spinal motor neurons. — PubMed · 1993 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 5 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1558014 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 1726 · accumulated records across collection walks 1726 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])