A subject this map covers
Neurotrophic factors
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Neuron-support proteins delivered by any route: injection, pump, cells or gene.
What does not belong here, however close it looks
Measuring these proteins in blood without delivering them is biomarker work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 446 records · 1976–2026
- Indexed as work in animals: 947 records · 1975–2026
- Indexed as laboratory work: 116 records · 1981–2026
- The source has not said who or what was studied: 221 records · 1997–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1730 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Increased levels of trkB mRNA and trkB protein-like immunoreactivity in the injured rat and cat spinal cord. — PubMed · 1992 · Journal Article
- Changes in nerve growth factor receptor-like immunoreactivity in the spinal cord after ventral funiculus lesion in adult cats. — PubMed · 1992 · Journal Article
- Increase in nerve growth factor-like immunoreactivity and decrease in choline acetyltransferase following contusive spinal cord injury. — PubMed · 1991 · Journal Article
- Increased nerve growth factor receptor mRNA in contused rat spinal cord. — PubMed · 1990 · Journal Article
- Effect of injury on nerve growth factor uptake by sensory ganglia. — PubMed · 1987 · Journal Article
- Neurotrophic activity in the central and peripheral nervous systems of the cat. Effects of injury. — PubMed · 1986 · Journal Article
- Promoting functional plasticity in the damaged nervous system. — PubMed · 1985 · Journal Article
- Progress in facilitating the recovery of function after central nervous system trauma. — PubMed · 1985 · Journal Article
- The influence of denervation and nerve growth factor on dorsal root axonal sprouting. — PubMed · 1985 · Journal Article
- Effects of nerve growth factor and its antibodies on sprouting of sensory axons following spinal cord hemisection. — PubMed · 1984 · Journal Article
- The effects of nerve growth factor and its antiserum on the postnatal development and survival after injury of sensory neurons in rat dorsal root ganglia. — PubMed · 1984 · Journal Article
- Role of thyroid function on CNS regeneration. — PubMed · 1984 · Journal Article
- History of central nervous system regeneration research. — PubMed · 1975 · Journal Article
Indexed as laboratory work
- Engineering integrin αvβ8-targeted extracellular vesicles to deliver BDNF mRNA for motor recovery in spinal cord injury. — PubMed · 2026 · Journal Article
- Functional Bioink and 3D Bioprinting Tissue Scaffold Applications for Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Advances in 3D bioprinting of functional biomaterials for neural tissue engineering. — PubMed · 2025 · Journal Article
- Neuroregenerative and neuroprotective effects of bioengineered scaffolds in spinal cord injury: a systematic review of preclinical and early phase clinical studies. — PubMed · 2025 · Journal Article
- Electric Stimulation Combined with Biomaterials for Repairing Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Development of Tissue-Engineered Model of Fibrotic Scarring after Spinal Cord Injury to Study Astrocyte Activation and Neurite Outgrowth In Vitro. — PubMed · 2024 · Journal Article
- Mussel shell-derived pro-regenerative scaffold with conductive porous multi-scale-patterned microenvironment for spinal cord injury repair. — PubMed · 2024 · Journal Article
- Electroacupuncture facilitates the integration of a grafted TrkC-modified mesenchymal stem cell-derived neural network into transected spinal cord in rats via increasing neurotrophin-3. — PubMed · 2021 · Journal Article
- 4D spatiotemporal modulation of biomolecules distribution in anisotropic corrugated microwrinkles via electrically manipulated microcapsules within hierarchical hydrogel for spinal cord regeneration. — PubMed · 2021 · Journal Article
- Select neurotrophins promote oligodendrocyte progenitor cell process outgrowth in the presence of chondroitin sulfate proteoglycans. — PubMed · 2021 · Journal Article
- 3D printable Sodium alginate-Matrigel (SA-MA) hydrogel facilitated ectomesenchymal stem cells (EMSCs) neuron differentiation. — PubMed · 2021 · Journal Article
- Histological and functional outcomes in a rat model of hemisected spinal cord with sustained VEGF/NT-3 release from tissue-engineered grafts. — PubMed · 2020 · Journal Article
- Docosahexaenoic Acid-Loaded Polylactic Acid Core-Shell Nanofiber Membranes for Regenerative Medicine after Spinal Cord Injury: In Vitro and In Vivo Study. — PubMed · 2020 · Journal Article
- Mechanically strengthened hybrid peptide-polyester hydrogel and potential applications in spinal cord injury repair. — PubMed · 2020 · Journal Article
- A combinatorial approach for spinal cord injury repair using multifunctional collagen-based matrices: development, characterization and impact on cell adhesion and axonal growth. — PubMed · 2020 · Journal Article
- A chitosan-based thermosensitive scaffold loaded with bone marrow-derived mesenchymal stem cells promotes motor function recovery in spinal cord injured mice. — PubMed · 2020 · Journal Article
- A micropatterned conductive electrospun nanofiber mesh combined with electrical stimulation for synergistically enhancing differentiation of rat neural stem cells. — PubMed · 2020 · Journal Article
- Determining Neurotrophin Gradients in Vitro To Direct Axonal Outgrowth Following Spinal Cord Injury. — PubMed · 2020 · Journal Article
- In vitro biocompatibility study of a water-rinsed biomimetic silk porous scaffold with olfactory ensheathing cells. — PubMed · 2019 · Journal Article
- Modeling traumatic injury in organotypic spinal cord slice culture obtained from adult rat. — PubMed · 2019 · Journal Article
- Polycaprolactone electrospun fiber scaffold loaded with iPSCs-NSCs and ASCs as a novel tissue engineering scaffold for the treatment of spinal cord injury. — PubMed · 2018 · Journal Article
- Bioprocessing strategies to enhance the challenging isolation of neuro-regenerative cells from olfactory mucosa. — PubMed · 2018 · Journal Article
- Neurotrophin-3 released from implant of tissue-engineered fibroin scaffolds inhibits inflammation, enhances nerve fiber regeneration, and improves motor function in canine spinal cord injury. — PubMed · 2018 · Journal Article
- Functional Multichannel Poly(Propylene Fumarate)-Collagen Scaffold with Collagen-Binding Neurotrophic Factor 3 Promotes Neural Regeneration After Transected Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Epidermal neural crest stem cell-derived glia enhance neurotrophic elements in an ex vivo model of spinal cord injury. — PubMed · 2018 · Journal Article
- Differently polarized macrophages affect the viability and growth of NSPCs by regulating the expression of PACAP. — PubMed · 2017 · Journal Article
- Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling. — PubMed · 2017 · Journal Article
- Conditioned medium of olfactory ensheathing cells promotes the functional recovery and axonal regeneration after contusive spinal cord injury. — PubMed · 2017 · Journal Article
- Strategies for neurotrophin-3 and chondroitinase ABC release from freeze-cast chitosan-alginate nerve-guidance scaffolds. — PubMed · 2017 · Journal Article
- Transplantation of tissue engineering neural network and formation of neuronal relay into the transected rat spinal cord. — PubMed · 2016 · Journal Article
- Bone marrow-derived mesenchymal stem cells in three-dimensional culture promote neuronal regeneration by neurotrophic protection and immunomodulation. — PubMed · 2016 · Journal Article
- Electrospun Fibers for Drug Delivery after Spinal Cord Injury and the Effects of Drug Incorporation on Fiber Properties. — PubMed · 2016 · Journal Article
- Effects of brain‑derived neurotrophic factor and neurotrophin‑3 on the neuronal differentiation of rat adipose‑derived stem cells. — PubMed · 2015 · Journal Article
- Studying Axonal Outgrowth and Regeneration of the Corticospinal Tract in Organotypic Slice Cultures. — PubMed · 2015 · Journal Article
- VEGF inhibits the inflammation in spinal cord injury through activation of autophagy. — PubMed · 2015 · Journal Article
- Integration of donor mesenchymal stem cell-derived neuron-like cells into host neural network after rat spinal cord transection. — PubMed · 2015 · Journal Article
- Donor mesenchymal stem cell-derived neural-like cells transdifferentiate into myelin-forming cells and promote axon regeneration in rat spinal cord transection. — PubMed · 2015 · Journal Article
- High purity of human oligodendrocyte progenitor cells obtained from neural stem cells: suitable for clinical application. — PubMed · 2015 · Journal Article
- Cellular transplantation-based evolving treatment options in spinal cord injury. — PubMed · 2015 · Journal Article
- Multifunctional therapeutic delivery strategies for effective neuro-regeneration following traumatic spinal cord injury. — PubMed · 2015 · Journal Article
- Effects of different sera conditions on olfactory ensheathing cells in vitro. — PubMed · 2014 · Journal Article
- Interleukin-1 receptor antagonist promotes survival of ventral horn neurons and suppresses microglial activation in mouse spinal cord slice cultures. — PubMed · 2014 · Journal Article
- Neuritogenic surfaces using natural product analogs. — PubMed · 2014 · Journal Article
- Primary olfactory mucosal cells promote axonal outgrowth in a three-dimensional assay. — PubMed · 2014 · Journal Article
- Graft of a tissue-engineered neural scaffold serves as a promising strategy to restore myelination after rat spinal cord transection. — PubMed · 2014 · Journal Article
- [Comparison of therapeutic effects of olfactory ensheathing cells derived from olfactory mucosa or olfactory bulb on spinal cord injury mouse models]. — PubMed · 2014 · Comparative Study
- Genetically modified Schwann cells producing glial cell line-derived neurotrophic factor inhibit neuronal apoptosis in rat spinal cord injury. — PubMed · 2014 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 5 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1558014 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 1726 · accumulated records across collection walks 1726 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neurotrophic factor" OR "BDNF" OR "neurotrophin-3" OR "GDNF") - Crossref
spinal cord injury neurotrophic factor BDNF - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Nerve Growth Factors"[MeSH Terms] OR "Brain-Derived Neurotrophic Factor"[MeSH Terms] OR "neurotrophic factor"[Title/Abstract] OR "BDNF"[Title/Abstract] OR "neurotrophin-3"[Title/Abstract] OR "GDNF"[Title/Abstract])