A subject this map covers
Yamanaka factors and partial reprogramming
Part of: Cell therapy
What belongs here
Delivery of reprogramming factors to living nervous-system cells to change their state short of pluripotency.
What does not belong here, however close it looks
The same factors used in a dish to make iPSC belong to the induced-pluripotent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 20 records · 2013–2026
- Indexed as work in animals: 17 records · 2016–2026
- Indexed as laboratory work: 3 records · 2017–2021
- The source has not said who or what was studied: 32 records · 1977–2025
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
72 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Reprogramming of astrocytes into motoneuron-like cells by a Ascl1-Myt1l-Pou3f2-Isl1 cocktail. — PubMed · 2026 · Journal Article
- Reprogramming the Inflammatory Response to Promote Neural Stem Cell Function After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Decoding TREM2 Signaling Pathways: Linking Macrophage Glycolysis to Inflammatory Diseases in the CNS. — PubMed · 2026 · Journal Article
- Thiorphan reprograms neurons to promote functional recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- Metabolic reprogramming through histone lactylation in microglia and macrophages recruits CD8(+) T lymphocytes and aggravates spinal cord injury. — PubMed · 2025 · Journal Article
- Metabolic Reprogramming in Spinal Cord Injury and Analysis of Potential Therapeutic Targets. — PubMed · 2025 · Journal Article
- Cell reprogramming for oligodendrocytes: A review of protocols and their applications to disease modeling and cell-based remyelination therapies. — PubMed · 2023 · Journal Article
- Spinal Cord Injury Induces Permanent Reprogramming of Microglia into a Disease-Associated State Which Contributes to Functional Recovery. — PubMed · 2021 · Journal Article
- Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1. — PubMed · 2021 · Journal Article
- A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair, generating improved genetically stable human induced pluripotent stem cells. — PubMed · 2021 · Journal Article
- Chromatin Interaction Changes during the iPSC-NPC Model to Facilitate the Study of Biologically Significant Genes Involved in Differentiation. — PubMed · 2020 · Journal Article
- Transplantation of neural scaffolds consisting of dermal fibroblast-reprogrammed neurons and 3D silk fibrous materials promotes the repair of spinal cord injury. — PubMed · 2019 · Journal Article
- Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury. — PubMed · 2018 · Journal Article
- Human neural progenitors derived from integration-free iPSCs for SCI therapy. — PubMed · 2017 · Journal Article
- Therapeutical Strategies for Spinal Cord Injury and a Promising Autologous Astrocyte-Based Therapy Using Efficient Reprogramming Techniques. — PubMed · 2016 · Journal Article
- From demyelination to remyelination: the road toward therapies for spinal cord injury. — PubMed · 2015 · Journal Article
- Efficient reprogramming of mouse fibroblasts to neuronal cells including dopaminergic neurons. — PubMed · 2014 · Journal Article
- The immunogenicity of cells derived from induced pluripotent stem cells. — PubMed · 2014 · Journal Article
- Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. — PubMed · 2013 · Journal Article
- Steps toward safe cell therapy using induced pluripotent stem cells. — PubMed · 2013 · Journal Article
Indexed as work in animals
- Polyamine metabolic reprogramming in ependymal cells promotes endogenous repair after spinal cord injury. — PubMed · 2026 · Journal Article
- A multi-omics atlas reveals spatially resolved sphingolipid metabolic reprogramming after spinal cord injury. — PubMed · 2026 · Journal Article
- Injectable Metal-Free Carbon Dot-Integrated Hydrogel for Regulating Inflammation via Macrophage Metabolic Reprograming in Spinal Cord Injury Therapy. — PubMed · 2026 · Journal Article
- Olfactory Mucosa Mesenchymal Stem Cell-Derived Exosomal lncRNA RMRP Regulates Glial Metabolic Reprogramming to Promote Axonal Regeneration After Spinal Cord Injury by Inhibiting WTAP-Mediated p53 m(6)A. — PubMed · 2026 · Journal Article
- Metabolic reprogramming in astrocytes prevents neuronal death through a UCHL1/PFKFB3/H4K8la positive feedback loop. — PubMed · 2025 · Journal Article
- Biomimetic piezoelectric hydrogel system for energy metabolism reprogramming in spinal cord injury repair. — PubMed · 2025 · Journal Article
- Decellularized tissue matrices hydrogels functionalized with extracellular vesicles promote macrophage reprogramming and neural stem cell differentiation for spinal cord injury repair. — PubMed · 2025 · Journal Article
- Metabolic Reprogramming of Neural Stem Cells by Chiral Nanofiber for Spinal Cord Injury. — PubMed · 2025 · Journal Article
- H4K12 Lactylation Activated-Spp1 in Reprogrammed Microglia Improves Functional Recovery After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice. — PubMed · 2024 · Journal Article
- Small molecules reprogram reactive astrocytes into neuronal cells in the injured adult spinal cord. — PubMed · 2024 · Journal Article
- Astrocytic reprogramming combined with rehabilitation strategy improves recovery from spinal cord injury. — PubMed · 2020 · Journal Article
- Sonic Hedgehog Effectively Improves Oct4-Mediated Reprogramming of Astrocytes into Neural Stem Cells. — PubMed · 2019 · Journal Article
- Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. — PubMed · 2018 · Journal Article
- [Astrocytes as therapeutic targets after spinal cord injury]. — PubMed · 2017 · Journal Article
- The p53 Pathway Controls SOX2-Mediated Reprogramming in the Adult Mouse Spinal Cord. — PubMed · 2016 · Journal Article
- A combination of small molecules directly reprograms mouse fibroblasts into neural stem cells. — PubMed · 2016 · Journal Article
Indexed as laboratory work
- Preparation of Neural Stem Cells and Progenitors: Neuronal Production and Grafting Applications. — PubMed · 2021 · Journal Article
- Engineering new neurons: in vivo reprogramming in mammalian brain and spinal cord. — PubMed · 2018 · Journal Article
- Therapeutic Application of Placental Mesenchymal Stem Cells Reprogrammed Neurospheres in Spinal Cord Injury of SCID. — PubMed · 2017 · Journal Article
The source has not said who or what was studied
- Challenges and Efficacy of Astrocyte-to-Neuron Reprogramming in Spinal Cord Injury: In Vitro Insights and In Vivo Outcomes. — PubMed · 2025 · Journal Article
- Reprogramming stem cells in regenerative medicine. — PubMed · 2022 · Journal Article
- Level of injury is an independent determining factor of gut dysbiosis in people with chronic spinal cord injury: A cross-sectional study — Crossref · 2022 · journal-article
- Cardiometabolic Risk Clustering in Spinal Cord Injury: Results of Exploratory Factor Analysis — Crossref · 2013 · journal-article
- International Spinal Cord Injury Data Sets for non-traumatic spinal cord injury — Crossref · 2013 · journal-article
- Musculoskeletal Aging in Spinal Cord Injury — Crossref · 2010 · journal-article
- Musculoskeletal Aging in Spinal Cord Injury — Crossref · 2010 · journal-article
- Erratum: Low-echoic lesions underneath the skin in subjects with spinal-cord injury — Crossref · 2009 · journal-article
- Platelet-activating factor biosynthesis in spinal cord contributes to neuropathic pain following peripheral nerve injury — Crossref · 2009 · journal-article
- Nontraumatic Spinal Cord Injury/Disease: Etiologies and Outcomes — Crossref · 2008 · journal-article
- Low-echoic lesions underneath the skin in subjects with spinal-cord injury — Crossref · 2008 · journal-article
- The correlation between nitric oxide and vascular endothelial growth factor in spinal cord injury — Crossref · 2007 · journal-article
- Pathophysiology of Obesity After Spinal Cord Injury — Crossref · 2007 · journal-article
- Pelvic somato-visceral reflexes after spinal cord injury: measures of functional loss and partial preservation — Crossref · 2006 · book-chapter
- Epidemiology of Extraspinal Fractures in Acute Spinal Cord Injury: Data from the Model Spinal Cord Injury Care Systems, 1973-1999 — Crossref · 2005 · journal-article
- Spinal Cord Injury Repair Strategies — Crossref · 2005 · journal-article
- Acute Rehabilitation in Cervical Spinal Cord Injury — Crossref · 2004 · journal-article
- Epidemiology of Cervical Spinal Cord Injury — Crossref · 2004 · journal-article
- Osteoporosis in Acute Spinal Cord Injury — Crossref · 2003 · journal-article
- Treatment of Pain in Persons with Spinal Cord Injury: Spinal Cord Stimulation and Intrathecal Drugs — Crossref · 2001 · journal-article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-17 | the source found 1865167 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 43 · this programme has 43 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("Yamanaka factor" OR "partial reprogramming" OR "OSKM" OR "cellular reprogramming") - Crossref
spinal cord injury Yamanaka factor partial reprogramming - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Cellular Reprogramming"[MeSH Terms] OR "Yamanaka factor"[Title/Abstract] OR "partial reprogramming"[Title/Abstract] OR "OSKM"[Title/Abstract] OR "cellular reprogramming"[Title/Abstract])