SCI Regeneration MapWhat the world knows about repairing the injured spinal cord

Seven directions of research

Transcutaneous spinal cord stimulation

A list of codes kept in this browser. No name, no medical answer and no account — nothing personal is stored and nothing is registered.

Relationship graph

Class: External device

What this is

The same idea without surgery: electrodes are stuck to the skin of the back and the current passes through the tissue to the spinal cord.

What problem it is trying to solve

An implant is available to few people and carries the risks of surgery. This approach asks whether part of the same effect can be had from outside, and for whom.

How it is supposed to work

The proposed mechanism is the same — raising the excitability of the cord's own networks. The current is more diffuse and weaker at the target, so both the dose and the placement are chosen differently.

Where this is known from: National Institute of Neurological Disorders and Stroke (NIH) · nobody has yet read that source against these sentences

What this acts on

The parts of the body and the phases of an injury this technology is aimed at, in plain words. Each one opens the rest of what is known about it.

Open this plate

The route across the top in five steps, from understanding the body to the evidence. Below it the whole column with the chest region lit and a level line across it, and beside it the cord in section with a bruise and its core, with four directions of research led to it on leaders from both sides.
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Plate 18Atlas of a spinal cord injury18of 19Seven directions,one lesionThe route of this atlasWhat the spinal cord is1What the spinal cord isThe ISNCSCI examination2The ISNCSCI examinationMotor signs3Motor signsThe rehabilitation context4The rehabilitation contextThe ladder of evidence5The ladder of evidenceThe route across the top in five steps, from understanding the body to the evidence. Below it the whole column with the chest region lit and a level line across it, and beside it the cord in section with a bruise and its core, with four directions of research led to it on leaders from both sides.Mapping the injury — The route across the top in five steps, from understanding the body to the evidence. Below it the whole column with the chest region lit and a level line across it, and beside it the cord in section with a bruise and its core, with four directions of research led to it on leaders from both sides.Making fibres grow againMaking fibres grow againBridging the gapBridging the gapBuilding a circuit around the gapBuilding a circuit around the gapTraining what remainsTraining what remainsWhat this map is forWhat this map is forMapping the injuryMapping the injury

What is being changed here, drawn

Seven directions, one lesion

The nervous system can reorganise. This direction is about training that uses the connections that survived, and about how to measure it.

Open this plate · 18 of 19 →

  • Training what remainsThe nervous system can reorganise. This direction is about training that uses the connections that survived, and about how to measure it.

How far this has actually got

No step has been recorded for this approach.

A step is recorded when a study in this corpus moves it. Nothing has, so there is no step to show — which is different from the step being zero.

Claims and their evidence states

Human and preclinical evidence are counted separately and never merged.

Human evidence

Nothing has been recorded here yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

Preclinical evidence

Nothing has been recorded here yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

Studies

No study has been recorded for this technology yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

Limits and known risks

It is less precise than an implant, and the current is limited by what the skin can tolerate. The effect usually lasts only during a session and shortly after it.

Safety signals

No safety signal has been recorded.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

Who researches this, and where

The sites are those the registry record names itself, word for word. A place that is absent was not published by the registry, and no location here is guessed.

Where this work was done

No place is recorded for the studies behind this technology.

A place is kept only where the source published one in the field its basis names. Some registry records do not publish a facility, and nothing is inferred from an address that was never given.

Laboratory

Nothing has been recorded here yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

Clinical trial

Nothing has been recorded here yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

What is still missing

What is missing: a shared standard for dose and electrode placement, and a direct comparison with implanted stimulation in the same people.

Completeness of the literature search

Nothing has been recorded here yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

The originals

Every record behind this page, with a way straight to the publication or the registry entry itself. Nothing here is our text.

No record in this corpus is attributed to this approach.

The searches that were run returned nothing a declared rule could attribute to it. The sources register says what was searched and what each source permits.

Found in the sources and not yet checked

Records the sources hold about this approach that nobody has read yet. They are not evidence and are not counted anywhere on this page.

See what the sources hold — 623 records

In detail: how all of this was measured

Nothing below has been removed or softened — it is the whole evidence model, one screen down, for anybody who wants to check the sentences above rather than take them.

Where this record was first named

The four states

Four separate statements. They are never rolled into one: a technology shown to work in rodents and never tried in people must read as exactly that.

Biologically possible

Not investigated

Nothing has been recorded either way.

Claims and their evidence states

Demonstrated in animals

Not investigated

Nothing has been recorded either way.

Claims and their evidence states

Demonstrated in humans

Not investigated

Nothing has been recorded either way.

Claims and their evidence states

Clinically available

Not investigated

Nothing has been recorded either way.

Claims and their evidence states

Combination · Prognostic value

Combination

No dataNothing has been recorded here yet. This is not a zero.

Prognostic value

No dataNothing has been recorded here yet. This is not a zero.

Readiness by injury phase and impairment band

CompleteSensory incompleteMotor incompleteMixedNot applicableAIS not reportedOutside our vocabulary
AcuteNo dataNo dataNo dataNo dataNo dataNo dataNo data
SubacuteNo dataNo dataNo dataNo dataNo dataNo dataNo data
ChronicNo dataNo dataNo dataNo dataNo dataNo dataNo data
UnknownNo dataNo dataNo dataNo dataNo dataNo dataNo data

Nothing has been recorded here yet. This is not a zero.

The eight evidence dimensions

No dataNothing has been recorded here yet. This is not a zero.

Technologies · Relationships

Nothing has been recorded here yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

Outcome measure

Nothing has been recorded here yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

Cell type, biomaterial or animal model

Nothing has been recorded here yet.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.

Relationships to other technologies

No relationship to another technology has been recorded.

This map holds only what has been read and checked against a source, and nothing has been recorded for this section. Empty here means exactly that — not zero, and not a fault in the page.