SCI Regeneration MapWhat the world knows about repairing the injured spinal cord

Seven directions of research · All six steps

3

Which functions may change

Movement, sensation, autonomic function, breathing — and how the level of an injury relates to what changes. Each function here filters real studies.

This is educational context. It is not a diagnosis, not a prognosis, not a treatment plan and not advice about any individual person. For anything urgent, seek professional help rather than an answer from a website.

9of 19Which functions may change

How a level is found

Open this plate

Three bodies side by side: the front with its strips of skin coloured and named C3 to S1, the back with the sacral strips where they actually are, and a third with the ten key muscles drawn as muscles and labelled by segment. Under them a table of five deep tendon reflexes: a drawing of the hammer on the limb each is tested in, its name, and the segments it answers for.
×
Plate 9Atlas of a spinal cord injury9of 19How a levelis foundDermatomeDermatomeMyotomeMyotomeFrontBackThe ten key musclesC3C4C5C6C7C8T1T2T4T6T8T10T12L1L2L3L4L5S1C2C3C4T2T6T10L1S3S4-5S2L5S1C5C6C7C8T1L2L3L4L5S1Elbow flexors · C5Wrist extensors · C6Elbow extensors · C7Finger flexors · C8Finger abductors · T1Hip flexors · L2Knee extensors · L3Ankle dorsiflexors · L4Long toe extensors · L5Ankle plantar flexors · S1ReflexesBiceps reflex · C5–C6Biceps reflex · C5–C6 — Three bodies side by side: the front with its strips of skin coloured and named C3 to S1, the back with the sacral strips where they actually are, and a third with the ten key muscles drawn as muscles and labelled by segment. Under them a table of five deep tendon reflexes: a drawing of the hammer on the limb each is tested in, its name, and the segments it answers for.Biceps reflex · C5–C6C5–C6Brachioradialis reflex · C6Brachioradialis reflex · C6 — Three bodies side by side: the front with its strips of skin coloured and named C3 to S1, the back with the sacral strips where they actually are, and a third with the ten key muscles drawn as muscles and labelled by segment. Under them a table of five deep tendon reflexes: a drawing of the hammer on the limb each is tested in, its name, and the segments it answers for.Brachioradialis reflex · C6C6Triceps reflex · C7Triceps reflex · C7 — Three bodies side by side: the front with its strips of skin coloured and named C3 to S1, the back with the sacral strips where they actually are, and a third with the ten key muscles drawn as muscles and labelled by segment. Under them a table of five deep tendon reflexes: a drawing of the hammer on the limb each is tested in, its name, and the segments it answers for.Triceps reflex · C7C7Patellar reflex · L3–L4Patellar reflex · L3–L4 — Three bodies side by side: the front with its strips of skin coloured and named C3 to S1, the back with the sacral strips where they actually are, and a third with the ten key muscles drawn as muscles and labelled by segment. Under them a table of five deep tendon reflexes: a drawing of the hammer on the limb each is tested in, its name, and the segments it answers for.Patellar reflex · L3–L4L3–L4Achilles reflex · S1–S2Achilles reflex · S1–S2 — Three bodies side by side: the front with its strips of skin coloured and named C3 to S1, the back with the sacral strips where they actually are, and a third with the ten key muscles drawn as muscles and labelled by segment. Under them a table of five deep tendon reflexes: a drawing of the hammer on the limb each is tested in, its name, and the segments it answers for.Achilles reflex · S1–S2S1–S2
  1. Dermatome

    The patch of skin whose sensation travels through one root. Dermatomes run across the body in bands, which is why testing sensation gives a level.

    What may change after an injuryThe line below which sensation has changed is one of the two things a neurological level is worked out from.

  2. Myotome

    The muscle group driven by one root. Testing the strength of key muscles gives a motor level the way dermatomes give a sensory one.

    What may change after an injuryThe level on the left and on the right can differ, so they are tested separately.

  3. Reflexes

    Automatic responses that close inside the cord without the brain. They report on the state of a pathway, not on effort.

    What may change after an injuryImmediately after an injury reflexes can disappear and return later. That is a distinct state and it has a name.

Also on this plate

  • Biceps reflex · C5–C6

    A tap on the biceps tendon bends the elbow. It answers for the upper cervical segments and tests whether they conduct.

  • Brachioradialis reflex · C6

    A tap over the radius near the wrist bends the forearm. It answers for the sixth cervical segment.

  • Triceps reflex · C7

    A tap on the triceps tendon straightens the elbow. It answers for the seventh cervical segment.

  • Patellar reflex · L3–L4

    A tap below the kneecap straightens the knee. It answers for the middle lumbar segments.

  • Achilles reflex · S1–S2

    A tap on the Achilles tendon points the foot downwards. It answers for the upper sacral segments.

Where this goes in the corpus

Motor function31measurements
Sensory function6measurements
Electrophysiology3measurements

10of 19Which functions may change

The level, and what it decides

Open this plate

The whole column on the left with its bones labelled, and four rows beside it, one per region. Each row carries a small body with everything below that level shaded — and the shading includes the arms only in the neck row, which is the difference the level makes.
×
Plate 10Atlas of a spinal cord injury10of 19The level, andwhat it decidesThe whole column on the left with its bones labelled, and four rows beside it, one per region. Each row carries a small body with everything below that level shaded — and the shading includes the arms only in the neck row, which is the difference the level makes.Injury at a cervical levelInjury at a cervical level — The whole column on the left with its bones labelled, and four rows beside it, one per region. Each row carries a small body with everything below that level shaded — and the shading includes the arms only in the neck row, which is the difference the level makes.1Injury at a cervical levelMovementBoth the arms and the legs are affected. Thehigher the level, the less control remains overshoulder, elbow and hand.SensationSensation is altered from the neck downwards, thearms included.Autonomic functionsControl of blood pressure and pulse, of bodytemperature, and of bladder and bowel isdisturbed.BreathingBreathing is at risk: the diaphragm is driven bysegments C3–C5, and an injury above them requiresventilator support.Injury at a thoracic levelInjury at a thoracic level — The whole column on the left with its bones labelled, and four rows beside it, one per region. Each row carries a small body with everything below that level shaded — and the shading includes the arms only in the neck row, which is the difference the level makes.2Injury at a thoracic levelMovementThe arms work. The legs are affected, and withthem the muscles of the trunk — the more so thehigher the level.SensationSensation is altered from the level downwards; onthe trunk the boundary runs as a band.Autonomic functionsAt T6 and above sudden surges of blood pressureare possible — a state that needs urgent help.Bladder and bowel are controlled differently.BreathingThe diaphragm works. Coughing and deep breathingare weaker, because the intercostal and abdominalmuscles are affected.Injury at a lumbar levelInjury at a lumbar level — The whole column on the left with its bones labelled, and four rows beside it, one per region. Each row carries a small body with everything below that level shaded — and the shading includes the arms only in the neck row, which is the difference the level makes.3Injury at a lumbar levelMovementArms and trunk work. Muscles of the hip, knee andfoot are affected — which ones depends on thelevel.SensationSensation is altered in the leg and the perineumaccording to the level.Autonomic functionsBladder and bowel are often flaccid rather thanspastic: the roots themselves are damaged, not thepathway above them.BreathingBreathing is not affected.Injury at a sacral levelInjury at a sacral level — The whole column on the left with its bones labelled, and four rows beside it, one per region. Each row carries a small body with everything below that level shaded — and the shading includes the arms only in the neck row, which is the difference the level makes.4Injury at a sacral levelMovementWalking is often preserved. The small muscles ofthe foot and the pelvic floor muscles areaffected.SensationSensation is altered in the perineum and the backof the leg — the "saddle" area.Autonomic functionsThis is the level that controls bladder, bowel andsexual function; here they are the most affected.BreathingBreathing is not affected.
  1. Injury at a cervical level

    Affects the arms, the trunk and the legs, and at a high level breathing as well. The higher the level, the more of the body lies below it.

    What may change after an injuryThe hand is what people ask about first. A small change in the hand often matters more to independence than a larger change elsewhere.

  2. Injury at a thoracic level

    The arms are usually spared. The trunk and the legs are affected; the level decides seated balance and trunk control.

  3. Injury at a lumbar level

    Mostly the legs. Bladder and bowel function can change as well.

  4. Injury at a sacral level

    Affects the feet, the bladder, the bowel and sexual function. The lowest sacral segments are what decide whether an injury is called complete.

Where this goes in the corpus

11of 19Which functions may change

Tetraplegia and paraplegia

Open this plate

The same body twice with the level marked across it. On the left the injury is in the neck and all four limbs and the trunk are shaded below it; on the right it is in the chest and the arms are outside the shading. Above each, the range of segments the word covers.
×
Plate 11Atlas of a spinal cord injury11of 19Tetraplegiaand paraplegiaTetraplegiaParaplegiaTetraplegia — The same body twice with the level marked across it. On the left the injury is in the neck and all four limbs and the trunk are shaded below it; on the right it is in the chest and the arms are outside the shading. Above each, the range of segments the word covers.Paraplegia — The same body twice with the level marked across it. On the left the injury is in the neck and all four limbs and the trunk are shaded below it; on the right it is in the chest and the arms are outside the shading. Above each, the range of segments the word covers.VSC1–T1T2–S5BreathingBreathingTetraplegiaTetraplegiaParaplegiaParaplegia
  1. Tetraplegia

    The word for the consequences of a cervical injury: all four limbs and the trunk are involved. It describes where the injury is, not how much function remains.

  2. Paraplegia

    The word for the consequences of a thoracic, lumbar or sacral injury: the arms are spared, the legs and part of the trunk are involved. Again a statement about location, not about amount.

  3. Breathing

    The work of the diaphragm and the intercostal muscles, and the strength of a cough. The diaphragm is driven from the cervical segments C3–C5.

    What may change after an injuryThe higher the cervical level, the more this is about breathing. A weak cough is a problem of its own, no smaller than breathing itself.

Where this goes in the corpus

What is missing at this step

This layer names the axes the corpus is indexed by. Where an axis holds no records, the panel says so and says what would change it — the gap is part of the answer.

What is still missing → · What is covered →

Where to look next

The same corpus, entered a different way: by question, by place, by connection, and by what changed recently. Every one of these reads the records this step has been pointing at.

124 medical statements · 6 authorities · 124 stand on an address that answered · 0 have been read against the source by a person

The last of those numbers is nought, and it is printed rather than left to be assumed. These explanations are ordinary anatomy and ordinary clinical vocabulary, written for this product, and each one names the authority it stands on; nobody has yet sat down and compared them, sentence by sentence, with the text at those addresses.