A subject this map covers
Antisense oligonucleotides and RNA therapy
Part of: Gene therapy
What belongs here
RNA molecules or their analogues given to change how a gene works after injury.
What does not belong here, however close it looks
MicroRNA as a biomarker without intervention is diagnostics, not therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 262 records · 1997–2026
- Indexed as work in animals: 612 records · 2000–2026
- Indexed as laboratory work: 28 records · 2007–2024
- The source has not said who or what was studied: 173 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1075 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Mesenchymal stem cell-derived small extracellular vesicles in spinal cord injury: From molecular repair mechanisms to standardized translational development. — PubMed · 2026 · Journal Article
- Engineering MSC-Derived Small Extracellular Vesicles for Targeted Cargo Delivery to the Injured Spinal Cord. — PubMed · 2026 · Journal Article
- LINC00707 Silencing Alleviates Inflammation and Oxidative Stress in LPS-stimulated BV2 Microglia via the miR-145-5p/TRAF6 Axis in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- MicroRNA-Ferroptosis-Spinal Cord Injury: A Complex Interplay in Neurodegeneration and Repair. — PubMed · 2026 · Journal Article
- [Research progress on the role of exosomal miRNA in spinal cord injury and intervention by traditional Chinese medicine]. — PubMed · 2026 · Journal Article
- MicroRNA-582-5p modulation of UBR5 affects inflammatory response and motor recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- MicroRNAs in Spinal Cord Injury: Molecular and Translational Insights. — PubMed · 2026 · Journal Article
- The investigation of human cerebrospinal fluid exosome in spinal cord injury. — PubMed · 2026 · Journal Article
- Association of Serum lncRNA CASC11 with Injury Severity and Inflammation in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- The immune dysregulation landscape and dynamic regulation of competing endogenous RNAs in spinal cord injury. — PubMed · 2026 · Journal Article
- miRNA-Mediated Regulation of Ferroptosis in Neurological Disorders: Mechanisms and Therapeutic Implications. — PubMed · 2026 · Journal Article
- miR-107-5p mitigates spinal cord injury by targeting the PLOD2/HK2 axis. — PubMed · 2026 · Journal Article
- Neuroprotective Role of THBS2 in Experimental Spinal Cord Injury Via its Anti-neuroinflammatory and Anti-apoptotic Properties. — PubMed · 2026 · Journal Article
- Recent advances in the application of engineered extracellular vesicles from mesenchymal stem cells for traumatic central nervous system. — PubMed · 2026 · Journal Article
- Exosome-derived microRNAs from stem cells from human exfoliated deciduous teeth (SHED): Emerging therapeutics for neurodegenerative disorders. — PubMed · 2026 · Journal Article
- Exosomal miR-149 from human umbilical cord mesenchymal stem cells attenuates spinal cord injury-induced blood-spinal cord barrier disruption by suppressing the ET-1/PI3K/Akt signaling pathway. — PubMed · 2025 · Journal Article
- Upregulation of miR-502-5p in traumatic spinal cord injury modulates neuroinflammation and oxidative stress by targeting FBXO28. — PubMed · 2025 · Journal Article
- The clinical significance of miR-18a-3p in traumatic spinal cord injury and its functional role in mediating apoptosis, inflammation and oxidative stress. — PubMed · 2025 · Journal Article
- Mesenchymal Stem Cell-Derived Exosomes: A Promising Therapeutic Strategy for Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Exosome-based therapeutic approach for spinal cord injury: A review. — PubMed · 2025 · Journal Article
- Extracellular vesicle-derived MicroRNAs as potential therapies for spinal cord and peripheral nerve injuries. — PubMed · 2025 · Journal Article
- Circulating microRNA Profiles in Acute Spinal Cord Injury: Evidence for Distinct Plasma Signatures Compared with Polytrauma Patients. — PubMed · 2025 · Journal Article
- Knowledge Structure, Research Hotspots and Emerging Trends in the Role of miRNAs in Neuropathic Pain: a Quantitative Analysis Using Python. — PubMed · 2025 · Journal Article
- Cerebrospinal fluid extracellular vesicle-derived miR-9-3p in spinal cord injury with neuroprotective implications and biomarker development. — PubMed · 2025 · Journal Article
- RNA Interference and Its Key Targets for Spinal Cord Injury Therapy: What Is Known So Far? — PubMed · 2025 · Journal Article
- Cross-linked genes analysis of programmed cell death and network pharmacological validation after spinal cord injury. — PubMed · 2025 · Journal Article
- Unraveling the role of MAG, PTEN, and NOTCH1 in axonal regeneration: a network analysis and molecular dynamics study of siRNA/drugs/nanocarriers interactions. — PubMed · 2025 · Journal Article
- The clinical application potential of miR-1287-5p in spinal cord injury resulting from spinal trauma and its involvement in modulating the inflammatory response. — PubMed · 2025 · Journal Article
- Selenized neural stem cell-derived exosomes: A neotype therapeutic agent for traumatic injuries of the central nervous system. — PubMed · 2025 · Journal Article
- Umbilical cord-derived exosomes alleviate spinal cord injury by regulating microglial polarization through miR-340-5p-mediated modulation of the JAK/STAT3 signaling pathway. — PubMed · 2025 · Journal Article
- Exosomes Derived from Tanshinone IIA-Pretreated Umbilical Cord Mesenchymal Stem Cells Repair Traumatic Spinal Cord Injury by miR-223-5p/USP8/NLRP3 Axis. — PubMed · 2025 · Journal Article
- CircGTF2H2C Regulates NLRP3 Dephosphorylation via Modulating PTPN11 Expression in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- miR-29c-3p downregulation accelerates spinal cord injury progression by targeting BRD4. — PubMed · 2025 · Journal Article
- Identifying pyroptosis- and inflammation-related genes in spinal cord injury based on bioinformatics analysis. — PubMed · 2025 · Journal Article
- Neuronal HDAC3 knockdown promotes propriospinal detour pathway formation and locomotor recovery in a mouse model of spinal cord injury. — PubMed · 2025 · Journal Article
- Administration of hypoxic pretreated adipose-derived mesenchymal stem cell exosomes promotes spinal cord repair after injury via delivery of circ-Astn1 and activation of autophagy. — PubMed · 2025 · Journal Article
- Nanoparticle delivery of CD68 siRNA inhibits neuroimmune responses by inhibiting activation of M1 macrophages. — PubMed · 2025 · Journal Article
- Exosome-shuttled miR-5121 from A2 astrocytes promotes BSCB repair after traumatic SCI by activating autophagy in vascular endothelial cells. — PubMed · 2025 · Journal Article
- Analysis and validation of programmed cell death genes associated with spinal cord injury progression based on bioinformatics and machine learning. — PubMed · 2025 · Journal Article
- Identification of Autophagy-Related Genes in Patients with Acute Spinal Cord Injury and Analysis of Potential Therapeutic Targets. — PubMed · 2025 · Journal Article
- IL-4-primed human umbilical cord mesenchymal stem cells-derived extracellular vesicles facilitate recovery in spinal cord injury via the miR-21-5p/PDCD4-mediated shifting of macrophage M1/M2 polarization. — PubMed · 2025 · Journal Article
- Stem Cell-Derived Extracellular Vesicle-Mediated Therapeutic Signaling in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Ferroptosis-related genes participate in the microglia-induced neuroinflammation of spinal cord injury via NF-κB signaling: evidence from integrated single-cell and spatial transcriptomic analysis. — PubMed · 2025 · Journal Article
- Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Exosomal MiRNA Therapy for Central Nervous System Injury Diseases. — PubMed · 2024 · Journal Article
- Unveiling vital biomarkers and immune infiltration profiles in endoplasmic reticulum stress following spinal cord injury. — PubMed · 2024 · Journal Article
- Identification of a New Role of miR-199a-5p as Factor Implied in Neuronal Damage: Decreasing the Expression of Its Target X-Linked Anti-Apoptotic Protein (XIAP) After SCI. — PubMed · 2024 · Journal Article
- The Ambivalent Role of miRNA-21 in Trauma and Acute Organ Injury. — PubMed · 2024 · Journal Article
- From apoptosis to pyroptosis: A two-decade analysis of spinal cord injury systematic review. — PubMed · 2024 · Journal Article
- Enhanced spinal cord repair using bioengineered induced pluripotent stem cell-derived exosomes loaded with miRNA. — PubMed · 2024 · Journal Article
- Mechanosensitive Piezo1 channels promote neurogenic bladder fibrosis via regulating TGF-β1/smad and Hippo/YAP1 pathways. — PubMed · 2024 · Journal Article
- Identification of coagulation diagnostic biomarkers related to the severity of spinal cord injury. — PubMed · 2024 · Journal Article
- Dysregulated MiR-223-5p Modulates Inflammation and Oxidative Stress in Traumatic Spinal Cord Injury. — PubMed · 2024 · Journal Article
- SNHG3 deficiency restrains spinal cord injury-induced inflammation through sponging miR-139-5p and provides a novel biomarker for disease severity. — PubMed · 2024 · Journal Article
- Spinal Cord Injury: From MicroRNAs to Exosomal MicroRNAs. — PubMed · 2024 · Journal Article
- Research progress of microRNA in spinal cord injury. — PubMed · 2024 · Journal Article
- Multi-platform omics sequencing dissects the atlas of plasma-derived exosomes in rats with or without depression-like behavior after traumatic spinal cord injury. — PubMed · 2024 · Journal Article
- SNHG7 regulates spinal cord injury-induced inflammatory response, oxidative stress, and apoptosis via the miR-199b-5p/TRAF3 axis. — PubMed · 2024 · Letter
- Targeted Repair of Spinal Cord Injury Based on miRNA-124-3p-Loaded Mesoporous Silica Camouflaged by Stem Cell Membrane Modified with Rabies Virus Glycoprotein. — PubMed · 2024 · Journal Article
- Long non-coding RNA H19 mediates osteogenic differentiation of bone marrow mesenchymal stem cells through the miR-29b-3p/DKK1 axis. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 854026 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-05 | the source found 2 · this programme has 1046 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("antisense oligonucleotide" OR "siRNA" OR "microRNA") - Crossref
spinal cord injury antisense oligonucleotide siRNA - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Oligonucleotides, Antisense"[MeSH Terms] OR "RNA, Small Interfering"[MeSH Terms] OR "MicroRNAs"[MeSH Terms] OR "antisense oligonucleotide"[Title/Abstract] OR "siRNA"[Title/Abstract] OR "microRNA"[Title/Abstract])