A subject this map covers
Antisense oligonucleotides and RNA therapy
Part of: Gene therapy
What belongs here
RNA molecules or their analogues given to change how a gene works after injury.
What does not belong here, however close it looks
MicroRNA as a biomarker without intervention is diagnostics, not therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 262 records · 1997–2026
- Indexed as work in animals: 612 records · 2000–2026
- Indexed as laboratory work: 28 records · 2007–2024
- The source has not said who or what was studied: 173 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1075 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Transplantation of MiR-28-5p-Modified BMSCs Promotes Functional Recovery After Spinal Cord Injury. — PubMed · 2024 · Journal Article
- BMSCs-derived exosomes inhibit macrophage/microglia pyroptosis by increasing autophagy through the miR-21a-5p/PELI1 axis in spinal cord injury. — PubMed · 2024 · Journal Article
- Novel SERS Signal Amplification Strategy for Ultrasensitive and Specific Detection of Spinal Cord Injury-Related miRNA. — PubMed · 2024 · Journal Article
- Small Extracellular Vesicles Released from miR-211-5p-Overexpressed Bone Marrow Mesenchymal Stem Cells Ameliorate Spinal Cord Injuries in Rats. — PubMed · 2024 · Journal Article
- METTL3 promotes microglial inflammation via MEF2C in spinal cord injury. — PubMed · 2024 · Journal Article
- Differential Expression of microRNAs and Target Genes Analysis in Olfactory Ensheathing Cell-derived Extracellular Vesicles Versus Olfactory Ensheathing Cells. — PubMed · 2024 · Journal Article
- Micro electrical fields induced MSC-sEVs attenuate neuronal cell apoptosis by activating autophagy via lncRNA MALAT1/miR-22-3p/SIRT1/AMPK axis in spinal cord injury. — PubMed · 2023 · Journal Article
- A Novel Magnetic Responsive miR-26a@SPIONs-OECs for Spinal Cord Injury: Triggering Neural Regeneration Program and Orienting Axon Guidance in Inhibitory Astrocytic Environment. — PubMed · 2023 · Journal Article
- PEG-SH-GNPs-SAPNS@miR-29a delivery system promotes neural regeneration and recovery of motor function after spinal cord injury. — PubMed · 2023 · Journal Article
- Role of Stem Cell-Derived Exosomes and microRNAs in Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Identification and Validation of Ferroptosis-Related Genes in Patients with Acute Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Emerging role of non-coding RNAs in neuroinflammation mediated by microglia and astrocytes. — PubMed · 2023 · Journal Article
- Iron induces B cell pyroptosis through Tom20-Bax-caspase-gasdermin E signaling to promote inflammation post-spinal cord injury. — PubMed · 2023 · Journal Article
- Differential Expression of Vascular-Related MicroRNA in Circulating Endothelial Microvesicles in Adults With Spinal Cord Injury: A Pilot Study. — PubMed · 2023 · Journal Article
- MiR-135a-5p/SP1 Axis Regulates Spinal Astrocyte Proliferation and Migration. — PubMed · 2023 · Journal Article
- Inflammatory stimulation of astrocytes affects the expression of miRNA-22-3p within NSCs-EVs regulating remyelination by targeting KDM3A. — PubMed · 2023 · Journal Article
- Therapeutic Potential of Combinative shRNA-Encoded Lentivirus-Mediated Gene Silencing to Accelerate Somatosensory Recovery After Spinal Cord Trauma. — PubMed · 2023 · Journal Article
- Research Progress of MicroRNAs in Spinal Cord Injury. — PubMed · 2023 · Journal Article
- circ_0013613 Promotes the recovery of spinal cord injury by regulating mir-370-3p/caspase1 to regulate neuronal pyroptosis. — PubMed · 2023 · Journal Article
- The Importance of Using Exosome-Loaded miRNA for the Treatment of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- The FGF/FGFR system in the microglial neuroinflammation with Borrelia burgdorferi: likely intersectionality with other neurological conditions. — PubMed · 2023 · Journal Article
- Specific Blood RNA Profiles in Individuals with Acute Spinal Cord Injury as Compared with Trauma Controls. — PubMed · 2023 · Journal Article
- Neuroprotective Role of MiRNA-9 in Neurological Diseases: A Mini Review. — PubMed · 2023 · Review
- The protective effects of curcumin on depression: Genes, transcription factors, and microRNAs involved. — PubMed · 2022 · Journal Article
- A functionalized collagen-I scaffold delivers microRNA 21-loaded exosomes for spinal cord injury repair. — PubMed · 2022 · Journal Article
- The Neuroprotection Effects of Exosome in Central Nervous System Injuries: a New Target for Therapeutic Intervention. — PubMed · 2022 · Journal Article
- Dysregulation of miR-301a-3p serves as a non-invasive biomarker and is associated with inflammatory responses in traumatic spinal cord injury. — PubMed · 2022 · Journal Article
- An update to pain management after spinal cord injury: from pharmacology to circRNAs. — PubMed · 2022 · Journal Article
- Clinical significance of miR-142-5p in spinal cord injury caused by spinal trauma and its functional role in the regulation of inflammation. — PubMed · 2022 · Journal Article
- Extracellular vesicles from human umbilical cord mesenchymal stem cells reduce lipopolysaccharide-induced spinal cord injury neuronal apoptosis by mediating miR-29b-3p/PTEN. — PubMed · 2022 · Journal Article
- MicroRNA-451 Attenuates the Inflammatory Response of Activated Microglia by Downregulating Nucleotide Binding Oligomerization Domain-Like Receptor Protein 3. — PubMed · 2022 · Journal Article
- Endothelial progenitor cells promote neural stem cell proliferation in hypoxic conditions through VEGF via the PI3K/AKT pathway. — PubMed · 2022 · Journal Article
- miR-124: A Promising Therapeutic Target for Central Nervous System Injuries and Diseases. — PubMed · 2022 · Journal Article
- MiR-487b suppressed inflammation and neuronal apoptosis in spinal cord injury by targeted Ifitm3. — PubMed · 2022 · Journal Article
- Targeting miR-21 in spinal cord injuries: a game-changer? — PubMed · 2022 · Journal Article
- Correlation between miRNA-124, miRNA-544a, and TNF-α levels in acute spinal cord injury. — PubMed · 2022 · Journal Article
- MicroRNA-148a-3p is a candidate mediator of increased bone marrow adiposity and bone loss following spinal cord injury. — PubMed · 2022 · Journal Article
- CircHIPK3 alleviates inflammatory response and neuronal apoptosis via regulating miR-382-5p/DUSP1 axis in spinal cord injury. — PubMed · 2022 · Journal Article
- MiRNAs as Promising Translational Strategies for Neuronal Repair and Regeneration in Spinal Cord Injury. — PubMed · 2022 · Journal Article
- MiR-181a-5p Alleviates the Inflammatory Response of PC12 Cells by Inhibiting High-Mobility Group Box-1 Protein Expression. — PubMed · 2022 · Journal Article
- The Role of miRNAs in Dexmedetomidine's Neuroprotective Effects against Brain Disorders. — PubMed · 2022 · Journal Article
- Exploring the role of non-coding RNAs in autophagy. — PubMed · 2022 · Journal Article
- Large-scale analysis of MicroRNA expression in motor neuron-like cells derived from human umbilical cord blood mesenchymal stem cells. — PubMed · 2022 · Journal Article
- Spinal cord injury: a study protocol for a systematic review and meta-analysis of microRNA alterations. — PubMed · 2022 · Journal Article
- An update on the roles of circular RNAs in spinal cord injury. — PubMed · 2022 · Journal Article
- Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury. — PubMed · 2022 · Journal Article
- miR-338-5p Levels and Cigarette Smoking are Associated With Neuropathic Pain Severity in Individuals With Spinal Cord Injury: Preliminary Findings From a Genome-Wide microRNA Expression Profiling Screen. — PubMed · 2022 · Journal Article
- Non-coding RNAs in the regulation of blood-brain barrier functions in central nervous system disorders. — PubMed · 2022 · Journal Article
- miR-672-3p Promotes Functional Recovery in Rats with Contusive Spinal Cord Injury by Inhibiting Ferroptosis Suppressor Protein 1. — PubMed · 2022 · Journal Article
- An Overview of Mesenchymal Stem Cell-based Therapy Mediated by Noncoding RNAs in the Treatment of Neurodegenerative Diseases. — PubMed · 2022 · Journal Article
- The Study of Cerebrospinal Fluid microRNAs in Spinal Cord Injury and Neurodegenerative Diseases: Methodological Problems and Possible Solutions. — PubMed · 2021 · Journal Article
- Transcription Factor SP2 Regulates Ski-mediated Astrocyte Proliferation In Vitro. — PubMed · 2021 · Journal Article
- Differentially-expressed mRNAs, microRNAs and long noncoding RNAs in intervertebral disc degeneration identified by RNA-sequencing. — PubMed · 2021 · Journal Article
- Identification of key pathways and RNAs associated with skeletal muscle atrophy after spinal cord injury. — PubMed · 2021 · Journal Article
- Long non-coding RNA TUG1 knockdown prevents neurons from death to alleviate acute spinal cord injury via the microRNA-338/BIK axis. — PubMed · 2021 · Journal Article
- Overexpression of miR-338-5p in exosomes derived from mesenchymal stromal cells provides neuroprotective effects by the Cnr1/Rap1/Akt pathway after spinal cord injury in rats. — PubMed · 2021 · Journal Article
- An update on the role of miR-379 in human disorders. — PubMed · 2021 · Journal Article
- Circ_HIPK3 alleviates CoCl(2)-induced apoptotic injury in neuronal cells by depending on the regulation of the miR-222-3p/DUSP19 axis. — PubMed · 2021 · Journal Article
- Circular RNA Plek promotes fibrogenic activation by regulating the miR-135b-5p/TGF-βR1 axis after spinal cord injury. — PubMed · 2021 · Journal Article
- Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injury. — PubMed · 2021 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 854026 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-05 | the source found 2 · this programme has 1046 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("antisense oligonucleotide" OR "siRNA" OR "microRNA") - Crossref
spinal cord injury antisense oligonucleotide siRNA - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Oligonucleotides, Antisense"[MeSH Terms] OR "RNA, Small Interfering"[MeSH Terms] OR "MicroRNAs"[MeSH Terms] OR "antisense oligonucleotide"[Title/Abstract] OR "siRNA"[Title/Abstract] OR "microRNA"[Title/Abstract])