A subject this map covers
Antisense oligonucleotides and RNA therapy
Part of: Gene therapy
What belongs here
RNA molecules or their analogues given to change how a gene works after injury.
What does not belong here, however close it looks
MicroRNA as a biomarker without intervention is diagnostics, not therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 262 records · 1997–2026
- Indexed as work in animals: 612 records · 2000–2026
- Indexed as laboratory work: 28 records · 2007–2024
- The source has not said who or what was studied: 173 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1075 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Extracellular vesicles go the extra mile after spinal cord injury. — PubMed · 2021 · Journal Article
- Research progress on the regulatory role of microRNAs in spinal cord injury. — PubMed · 2021 · Journal Article
- The role of exosomal microRNAs in central nervous system diseases. — PubMed · 2021 · Journal Article
- Biomarkers mining for spinal cord injury based on integrated multi-transcriptome expression profile data. — PubMed · 2021 · Journal Article
- MicroRNA-24-3p Inhibits Microglia Inflammation by Regulating MK2 Following Spinal Cord Injury. — PubMed · 2021 · Journal Article
- MiR-122-5p Mitigates Inflammation, Reactive Oxygen Species and SH-SY5Y Apoptosis by Targeting CPEB1 After Spinal Cord Injury Via the PI3K/AKT Signaling Pathway. — PubMed · 2021 · Journal Article
- Preclinical Experimental Applications of miRNA Loaded BMSC Extracellular Vesicles. — PubMed · 2021 · Journal Article
- MiR-665 inhibits inflammatory response in microglia following spinal cord injury by targeting TREM2. — PubMed · 2021 · Journal Article
- MiRNA-194-5p inhibits inflammatory response after spinal cord injury via regulating TRAF6. — PubMed · 2020 · Letter
- Stem-like cells of various origins showed therapeutic effect to improve the recovery of spinal cord injury. — PubMed · 2020 · Journal Article The source marks this record as retracted.
- The effect of periaqueductal gray's metabotropic glutamate receptor subtype 8 activation on locomotor function following spinal cord injury. — PubMed · 2020 · Journal Article
- Identification of a circRNA-miRNA-mRNA network to explore the effects of circRNAs on pathogenesis and treatment of spinal cord injury. — PubMed · 2020 · Journal Article
- [Inhibitory effect of miR-429 on expressions of ZO-1, Occludin, and Claudin-5 proteins to improve the permeability of blood spinal cord barrier in vitro]. — PubMed · 2020 · Journal Article
- Dysregulation in the expression of (lncRNA-TSIX, TP53INP2 mRNA, miRNA-1283) in spinal cord injury. — PubMed · 2020 · Journal Article
- Silencing of Long Non-Coding RNA (lncRNA) Nuclear Paraspeckle Assembly Transcript 1 (NEAT1) Protects PC-12 Cells from LPS-Induced Injury via Targeting miR-29a. — PubMed · 2020 · Journal Article
- TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury. — PubMed · 2020 · Journal Article
- A circRNA derived from linear HIPK3 relieves the neuronal cell apoptosis in spinal cord injury via ceRNA pattern. — PubMed · 2020 · Journal Article
- Transcriptional repression of PTEN in neural cells using CRISPR/dCas9 epigenetic editing. — PubMed · 2020 · Journal Article
- MicroRNA‑138‑5p regulates the development of spinal cord injury by targeting SIRT1. — PubMed · 2020 · Journal Article
- The emerging roles of circular RNAs in CNS injuries. — PubMed · 2020 · Journal Article
- The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation. — PubMed · 2020 · Journal Article
- Upregulation of microRNA-200a in bone marrow mesenchymal stem cells enhances the repair of spinal cord injury in rats by reducing oxidative stress and regulating Keap1/Nrf2 pathway. — PubMed · 2020 · Journal Article
- MicroRNA-21-5p promotes the inflammatory response after spinal cord injury by targeting PLAG1. — PubMed · 2020 · Journal Article
- MiR-429 regulates blood-spinal cord barrier permeability by targeting Krüppel-like factor 6. — PubMed · 2020 · Journal Article
- Central Neuropathic Mechanisms in Pain Signaling Pathways: Current Evidence and Recommendations. — PubMed · 2020 · Journal Article
- Long noncoding RNA PTENP1 affects the recovery of spinal cord injury by regulating the expression of miR-19b and miR-21. — PubMed · 2020 · Journal Article
- MiR-34a may Function as Potential Biomarker for Remission after Traumatic Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Overexpression of miRNA-433-5p protects acute spinal cord injury through activating MAPK1. — PubMed · 2020 · Journal Article
- A proteolytic C-terminal fragment of Nogo-A (reticulon-4A) is released in exosomes and potently inhibits axon regeneration. — PubMed · 2020 · Journal Article
- Exosomes Derived from miR-126-modified MSCs Promote Angiogenesis and Neurogenesis and Attenuate Apoptosis after Spinal Cord Injury in Rats. — PubMed · 2020 · Journal Article
- [Non-coding RNAs as therapeutic targets in spinal cord injury]. — PubMed · 2020 · Journal Article
- UTX/KDM6A Deletion Promotes Recovery of Spinal Cord Injury by Epigenetically Regulating Vascular Regeneration. — PubMed · 2019 · Journal Article
- MiR-21 derived from the exosomes of MSCs regulates the death and differentiation of neurons in patients with spinal cord injury. — PubMed · 2019 · Journal Article
- MiR-325-3p promotes locomotor function recovery in rats with spinal cord injury via inhibiting the expression of neutrophil elastase. — PubMed · 2019 · Journal Article
- MiR-92b-3p promotes neurite growth and functional recovery via the PTEN/AKT pathway in acute spinal cord injury. — PubMed · 2019 · Journal Article
- Sirtuin4 suppresses the anti-neuroinflammatory activity of infiltrating regulatory T cells in the traumatically injured spinal cord. — PubMed · 2019 · Journal Article
- MicroRNA-15a inhibits inflammatory response and apoptosis after spinal cord injury via targeting STAT3. — PubMed · 2019 · Journal Article
- MicroRNA-135a-5p reduces P2X(7) -dependent rise in intracellular calcium and protects against excitotoxicity. — PubMed · 2019 · Journal Article
- Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Bioinformatics analysis of circulating miRNAs related to cancer following spinal cord injury. — PubMed · 2019 · Journal Article
- REPLY: Microrna-based spinal cord protection: The possible side effect cannot be neglected. — PubMed · 2019 · Letter
- Long non-coding RNA Mirt2 relieves lipopolysaccharide-induced injury in PC12 cells by suppressing miR-429. — PubMed · 2019 · Journal Article
- MicroRNA Biomarkers in Cerebrospinal Fluid and Serum Reflect Injury Severity in Human Acute Traumatic Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Cell fate regulation by reticulon-4 in human prostate cancers. — PubMed · 2019 · Journal Article
- miR-21 and miR-19b delivered by hMSC-derived EVs regulate the apoptosis and differentiation of neurons in patients with spinal cord injury. — PubMed · 2019 · Journal Article
- Overexpression of lncRNA TCTN2 protects neurons from apoptosis by enhancing cell autophagy in spinal cord injury. — PubMed · 2019 · Journal Article
- miR-155-5p Promotes Dorsal Root Ganglion Neuron Axonal Growth in an Inhibitory Microenvironment via the cAMP/PKA Pathway. — PubMed · 2019 · Journal Article
- Inhibition of miR-17-5p promotes mesenchymal stem cells to repair spinal cord injury. — PubMed · 2019 · Journal Article
- LINC00969 promotes the degeneration of intervertebral disk by sponging miR-335-3p and regulating NLRP3 inflammasome activation. — PubMed · 2019 · Journal Article
- Acute Spinal Cord Injury: A Systematic Review Investigating miRNA Families Involved. — PubMed · 2019 · Journal Article
- Construction and analysis of a spinal cord injury competitive endogenous RNA network based on the expression data of long noncoding, micro‑ and messenger RNAs. — PubMed · 2019 · Journal Article
- Protective Effects of CISD2 and Influence of Curcumin on CISD2 Expression in Aged Animals and Inflammatory Cell Model. — PubMed · 2019 · Journal Article
- Circulating microRNAs, Vascular Risk, and Physical Activity in Spinal Cord-Injured Subjects. — PubMed · 2019 · Journal Article
- MicroRNAs in contusion spinal cord injury: pathophysiology and clinical utility. — PubMed · 2019 · Journal Article
- The acute phase serum zinc concentration is a reliable biomarker for predicting the functional outcome after spinal cord injury. — PubMed · 2019 · Journal Article
- An in vitro model for studying CNS white matter: functional properties and experimental approaches. — PubMed · 2019 · Journal Article
- Delivery of Antisense Oligonucleotides Mediated by a Hydrogel System: In Vitro and In Vivo Application in the Context of Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Effect of exosomes derived from MiR-133b-modified ADSCs on the recovery of neurological function after SCI. — PubMed · 2019 · Journal Article
- Emerging roles of long non-coding RNAs in neuropathic pain. — PubMed · 2019 · Journal Article
- MiR-219-5p promotes spinal cord injury recovery by inhibiting NEUROD2-regulated inflammation and oxidative stress. — PubMed · 2019 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 854026 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-05 | the source found 2 · this programme has 1046 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("antisense oligonucleotide" OR "siRNA" OR "microRNA") - Crossref
spinal cord injury antisense oligonucleotide siRNA - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Oligonucleotides, Antisense"[MeSH Terms] OR "RNA, Small Interfering"[MeSH Terms] OR "MicroRNAs"[MeSH Terms] OR "antisense oligonucleotide"[Title/Abstract] OR "siRNA"[Title/Abstract] OR "microRNA"[Title/Abstract])