A subject this map covers
Gene editing
Part of: Gene therapy
What belongs here
Direct change of gene sequence or regulation in cells of the injured cord.
What does not belong here, however close it looks
CRISPR used only as a laboratory screening tool is laboratory work.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 22 records · 2015–2025
- Indexed as work in animals: 16 records · 2017–2026
- Indexed as laboratory work: 2 records · 2023–2025
- The source has not said who or what was studied: 71 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
111 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Addressing the challenges of immunogenicity, heterogeneity and tumorigenicity in the clinical translation of human embryonic stem cells. — PubMed · 2025 · Journal Article
- Spinal Cord Injury 2.0: Bridging the Gap Between Neurobiology, Technology, and Hope in the Era of Precision Medicine. — PubMed · 2025 · Journal Article
- RNA Interference and Its Key Targets for Spinal Cord Injury Therapy: What Is Known So Far? — PubMed · 2025 · Journal Article
- CRISPR and Artificial Intelligence in Neuroregeneration: Closed-Loop Strategies for Precision Medicine, Spinal Cord Repair, and Adaptive Neuro-Oncology. — PubMed · 2025 · Journal Article
- Precision Recovery After Spinal Cord Injury: Integrating CRISPR Technologies, AI-Driven Therapeutics, Single-Cell Omics, and System Neuroregeneration. — PubMed · 2025 · Journal Article
- Enhancing Functional Recovery After Spinal Cord Injury Through Neuroplasticity: A Comprehensive Review. — PubMed · 2025 · Journal Article
- Stem cell therapy: a revolutionary cure or a pandora's box. — PubMed · 2025 · Journal Article
- Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases. — PubMed · 2025 · Journal Article
- Personalized Stem Cell-Based Regeneration in Spinal Cord Injury Care. — PubMed · 2025 · Journal Article
- Revolutionizing medicine: recent developments and future prospects in stem-cell therapy. — PubMed · 2024 · Journal Article
- Stem cell therapies for neurological disorders: current progress, challenges, and future perspectives. — PubMed · 2024 · Journal Article
- Cell Transplantation for Repair of the Spinal Cord and Prospects for Generating Region-Specific Exogenic Neuronal Cells. — PubMed · 2024 · Journal Article
- Spinal cord injury: Olfactory ensheathing cell-based therapeutic strategies. — PubMed · 2024 · Journal Article
- Prevention of Oxidative Damage in Spinal Cord Ischemia Upon Aortic Surgery: First-In-Human Results of Shock Wave Therapy Prove Safety and Feasibility. — PubMed · 2022 · Journal Article
- Spinal cord injury target-immunotherapy with TNF-α autoregulated and feedback-controlled human umbilical cord mesenchymal stem cell derived exosomes remodelled by CRISPR/Cas9 plasmid. — PubMed · 2022 · Journal Article
- Transcriptional repression of PTEN in neural cells using CRISPR/dCas9 epigenetic editing. — PubMed · 2020 · Journal Article
- CRISPR, Prime Editing, Optogenetics, and DREADDs: New Therapeutic Approaches Provided by Emerging Technologies in the Treatment of Spinal Cord Injury. — PubMed · 2020 · Journal Article
- GDNF rescues the fate of neural progenitor grafts by attenuating Notch signals in the injured spinal cord in rodents. — PubMed · 2020 · Journal Article
- Editors' note. — PubMed · 2019 · Editorial
- Recent advances in nanotherapeutic strategies for spinal cord injury repair. — PubMed · 2019 · Journal Article
- Translational Relevance of Swine Models of Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Pluripotent stem cell applications for regenerative medicine. — PubMed · 2015 · Journal Article
Indexed as work in animals
- Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1-Mediated Mechanotransduction. — PubMed · 2026 · Journal Article
- TRIM14 Inhibition Suppresses Microglial Polarization and Pyroptosis Through the NF-κB/NLRP3 Pathway to Enhance Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
- Single-cell analysis of innate spinal cord regeneration identifies intersecting modes of neuronal repair. — PubMed · 2024 · Journal Article
- Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome. — PubMed · 2023 · Journal Article
- Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Hop Mice Display Synchronous Hindlimb Locomotion and a Ventrally Fused Lumbar Spinal Cord Caused by a Point Mutation in Ttc26. — PubMed · 2022 · Journal Article
- Efficient CRISPR/Cas9 mutagenesis for neurobehavioral screening in adult zebrafish. — PubMed · 2021 · Journal Article
- CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury. — PubMed · 2021 · Journal Article
- Localized EMT reprograms glial progenitors to promote spinal cord repair. — PubMed · 2021 · Journal Article
- Direct Gene Knock-out of Axolotl Spinal Cord Neural Stem Cells via Electroporation of CAS9 Protein-gRNA Complexes. — PubMed · 2019 · Journal Article
- An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle. — PubMed · 2019 · Journal Article
- Salamander spinal cord regeneration: The ultimate positive control in vertebrate spinal cord regeneration. — PubMed · 2017 · Journal Article
- Xenopus laevis as a Model Organism for the Study of Spinal Cord Formation, Development, Function and Regeneration. — PubMed · 2017 · Journal Article
- Reduced FAK-STAT3 signaling contributes to ER stress-induced mitochondrial dysfunction and death in endothelial cells. — PubMed · 2017 · Journal Article
- The African clawed frog Xenopus laevis: A model organism to study regeneration of the central nervous system. — PubMed · 2017 · Journal Article
- Learning to swim, again: Axon regeneration in fish. — PubMed · 2017 · Journal Article
Indexed as laboratory work
- Bone Tissue Engineering: From Biomaterials to Clinical Trials. — PubMed · 2025 · Journal Article
- Advancing Spinal Cord Injury Treatment through Stem Cell Therapy: A Comprehensive Review of Cell Types, Challenges, and Emerging Technologies in Regenerative Medicine. — PubMed · 2023 · Journal Article
The source has not said who or what was studied
- Microenvironmental and transcriptional determinants of the robustness of spinal cord regeneration in zebrafish. — PubMed · 2026 · Journal Article
- Neuronal SPI1 suppression enhances axonal regeneration after spinal cord injury through Rassf10 downregulation. — PubMed · 2026 · Journal Article
- ID3 -depleted human induced pluripotent stem cell-derived neural stem/progenitor cells promote neurorepair. — PubMed · 2026 · Journal Article
- Glycosaminoglycans in axon growth and regeneration: molecular mechanisms and therapeutic implications. — PubMed · 2026 · Journal Article
- Current status of neural progenitor/stem cells for spinal cord injury: fundamental research and clinical trials. — PubMed · 2026 · Journal Article
- Current status and future prospects of functionalized mesenchymal stem cells for the treatment of spinal cord injury. — PubMed · 2026 · Journal Article
- Effect of mitochondrial dysfunction on scar formation after spinal cord injury. — PubMed · 2026 · Journal Article
- Cultivation and transplantation of engineered stem cells: A new strategy for promoting repair of central nervous system injury. — PubMed · 2026 · Journal Article
- The role of gene therapy in neural injury repair. — PubMed · 2026 · Journal Article
- Integrating 3D bioprinting and neural stem cell therapy for central nervous system repair: implications for regenerative neurosurgery. — PubMed · 2026 · Journal Article
- Beyond Transplantation: Engineering Neural Cell Therapies and Combination Strategies for Spinal Cord Repair. — PubMed · 2026 · Journal Article
- Innovative approaches in neural stem cell therapy: a comprehensive review of mechanisms and applications. — PubMed · 2025 · Journal Article
- Macrophage Migration Inhibitory Factor Suppresses Natural Killer Cell Response and Promotes Hypoimmunogenic Stem Cell Engraftment Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Macrophage Migration Inhibitory Factor Suppresses Natural Killer Cell Response and Promotes Hypoimmunogenic Stem Cell Engraftment Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Stem Cell-Based Approaches for Spinal Cord Injury: The Promise of iPSCs. — PubMed · 2025 · Journal Article
- The CRISPR Code: Gene Editing, Biotechnology, and the Future of Humanity — Crossref · 2025 · book-chapter
- A Comprehensive Review of the Role of Stem Cells in Neuroregeneration: Potential Therapies for Neurological Disorders. — PubMed · 2024 · Journal Article
- The Current Update of Conventional and Innovative Treatment Strategies for Central Nervous System Injury. — PubMed · 2024 · Journal Article
- Development of a mouse model of chronic ventral spinal cord compression: Neurobehavioral, radiological, and pathological changes. — PubMed · 2024 · Journal Article
- Understanding the pathophysiology of acute critical illness: translational lessons from zebrafish models. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1794933 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 2 · this programme has 65 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("CRISPR" OR "gene editing") - Crossref
spinal cord injury CRISPR gene editing - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gene Editing"[MeSH Terms] OR "CRISPR-Cas Systems"[MeSH Terms] OR "CRISPR"[Title/Abstract] OR "gene editing"[Title/Abstract])