A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- mTOR pathway: A potential therapeutic target for spinal cord injury. — PubMed · 2022 · Journal Article
- 'Scary' pericytes: the fibrotic scar in brain and spinal cord lesions. — PubMed · 2022 · Journal Article
- The role of aquaporin 4 (AQP4) in spinal cord injury. — PubMed · 2022 · Journal Article
- Transcription Factor SP2 Regulates Ski-mediated Astrocyte Proliferation In Vitro. — PubMed · 2021 · Journal Article
- Neuroinflammation and Scarring After Spinal Cord Injury: Therapeutic Roles of MSCs on Inflammation and Glial Scar. — PubMed · 2021 · Journal Article
- Evaluation of Traumatic Spinal Cord Injury in a Rat Model Using (99m)Tc-GA-5 as a Potential In Vivo Tracer. — PubMed · 2021 · Journal Article
- 3D spheroids of human placenta-derived mesenchymal stem cells attenuate spinal cord injury in mice. — PubMed · 2021 · Journal Article
- Effect of Schwann cell transplantation combined with electroacupuncture on axonal regeneration and remyelination in rats with spinal cord injury. — PubMed · 2021 · Journal Article
- Nkx6.1 enhances neural stem cell activation and attenuates glial scar formation and neuroinflammation in the adult injured spinal cord. — PubMed · 2021 · Journal Article
- Protective Effects of Estrogen via Nanoparticle Delivery to Attenuate Myelin Loss and Neuronal Death after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions. — PubMed · 2021 · Journal Article
- Spinal cord regeneration: A brief overview of the present scenario and a sneak peek into the future. — PubMed · 2021 · Journal Article
- The Structure of the Spinal Cord Ependymal Region in Adult Humans Is a Distinctive Trait among Mammals. — PubMed · 2021 · Comparative Study
- Engineered basic fibroblast growth factor-overexpressing human umbilical cord-derived mesenchymal stem cells improve the proliferation and neuronal differentiation of endogenous neural stem cells and functional recovery of spinal cord injury by activating the PI3K-Akt-GSK-3β signaling pathway. — PubMed · 2021 · Journal Article
- The influence of ApoE4 on the clinical outcomes and pathophysiology of degenerative cervical myelopathy. — PubMed · 2021 · Journal Article
- Plasticity of the Injured Spinal Cord. — PubMed · 2021 · Journal Article
- Current Concepts of Stem Cell Therapy for Chronic Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Neural circuit repair after central nervous system injury. — PubMed · 2021 · Journal Article
- Dual-Cues Laden Scaffold Facilitates Neurovascular Regeneration and Motor Functional Recovery After Complete Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Regionally Specific Human Pre-Oligodendrocyte Progenitor Cells Produce Both Oligodendrocytes and Neurons after Transplantation in a Chronically Injured Spinal Cord Rat Model after Glial Scar Ablation. — PubMed · 2021 · Journal Article
- Inhibition of astrocyte hemichannel improves recovery from spinal cord injury. — PubMed · 2021 · Journal Article
- Optimal Preclinical Conditions for Using Adult Human Multipotent Neural Cells in the Treatment of Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Biomaterials and strategies for repairing spinal cord lesions. — PubMed · 2021 · Journal Article
- Early and sustained improvements in motor function in rats after infusion of allogeneic umbilical cord-derived mesenchymal stem cells following spinal cord injury. — PubMed · 2021 · Journal Article
- Functionalized nanogel for treating activated astrocytes in spinal cord injury. — PubMed · 2021 · Journal Article
- Systematic analysis of purified astrocytes after SCI unveils Zeb2os function during astrogliosis. — PubMed · 2021 · Journal Article
- Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases. — PubMed · 2021 · Journal Article
- The Pathogenesis of Neurotrauma Indicates Targets for Neuroprotective Therapies. — PubMed · 2021 · Journal Article
- The Role of Astrogliosis in Formation of the Syrinx in Spinal Cord Injury. — PubMed · 2021 · Journal Article
- The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury. — PubMed · 2020 · Journal Article
- Bioactive Elastic Scaffolds Loaded with Neural Stem Cells Promote Rapid Spinal Cord Regeneration. — PubMed · 2020 · Journal Article
- TGFβ3 is neuroprotective and alleviates the neurotoxic response induced by aligned poly-l-lactic acid fibers on naïve and activated primary astrocytes. — PubMed · 2020 · Journal Article
- Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma. — PubMed · 2020 · Journal Article
- Subarachnoid transplantation of human umbilical cord mesenchymal stem cell in rodent model with subacute incomplete spinal cord injury: Preclinical safety and efficacy study. — PubMed · 2020 · Journal Article
- Effective Modulation of CNS Inhibitory Microenvironment using Bioinspired Hybrid-Nanoscaffold-Based Therapeutic Interventions. — PubMed · 2020 · Journal Article
- Softening of the chronic hemi-section spinal cord injury scar parallels dysregulation of cellular and extracellular matrix content. — PubMed · 2020 · Journal Article
- Aligned collagen scaffold combination with human spinal cord-derived neural stem cells to improve spinal cord injury repair. — PubMed · 2020 · Journal Article
- Cerebrospinal fluid levels of GFAP and pNF-H are elevated in patients with chronic spinal cord injury and neurological deterioration. — PubMed · 2020 · Journal Article
- Reactive Astrogliosis: Implications in Spinal Cord Injury Progression and Therapy. — PubMed · 2020 · Journal Article
- Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery. — PubMed · 2020 · Journal Article
- Inverse Electron-Demand Diels-Alder Methylcellulose Hydrogels Enable the Co-delivery of Chondroitinase ABC and Neural Progenitor Cells. — PubMed · 2020 · Journal Article
- Chronic Hyperglycemia before Spinal Cord Injury Increases Inflammatory Reaction and Astrogliosis after Injury: Human and Rat Studies. — PubMed · 2020 · Journal Article
- The repair and autophagy mechanisms of hypoxia-regulated bFGF-modified primary embryonic neural stem cells in spinal cord injury. — PubMed · 2020 · Journal Article
- An injectable recombinant human milk fat globule-epidermal growth factor 8-loaded copolymer system for spinal cord injury reduces inflammation through NF-κB and neuronal cell death. — PubMed · 2020 · Journal Article
- Prolonged inflammation leads to ongoing damage after spinal cord injury. — PubMed · 2020 · Journal Article
- Comparison of Regenerative Effects of Transplanting Three-Dimensional Longitudinal Scaffold Loaded-Human Mesenchymal Stem Cells and Human Neural Stem Cells on Spinal Cord Completely Transected Rats. — PubMed · 2020 · Journal Article
- Enhancing myelin repair in experimental model of multiple sclerosis using immobilized chondroitinase ABC I on porous silicon nanoparticles. — PubMed · 2020 · Journal Article
- Exercise in multiple sclerosis and its models: Focus on the central nervous system outcomes. — PubMed · 2020 · Journal Article
- Glial Scar-a Promising Target for Improving Outcomes After CNS Injury. — PubMed · 2020 · Journal Article
- The Neuroprotective Role of Reactive Astrocytes after Central Nervous System Injury. — PubMed · 2020 · Journal Article
- Vascularization of self-assembled peptide scaffolds for spinal cord injury repair. — PubMed · 2020 · Journal Article
- Treatment of rats with spinal cord injury using human bone marrow-derived stromal cells prepared by negative selection. — PubMed · 2020 · Comparative Study
- Targeting Chondroitin Sulfate Proteoglycans: An Emerging Therapeutic Strategy to Treat CNS Injury. — PubMed · 2020 · Journal Article
- Spinal Cord Injury Results in Chronic Mechanical Stiffening. — PubMed · 2020 · Journal Article
- Selective Modulation of A1 Astrocytes by Drug-Loaded Nano-Structured Gel in Spinal Cord Injury. — PubMed · 2020 · Journal Article
- A prevascularized nerve conduit based on a stem cell sheet effectively promotes the repair of transected spinal cord injury. — PubMed · 2020 · Journal Article
- Large-Scale Automated Hollow-Fiber Bioreactor Expansion of Umbilical Cord-Derived Human Mesenchymal Stromal Cells for Neurological Disorders. — PubMed · 2020 · Journal Article
- Elucidating the Role of Apolipoprotein E Isoforms in Spinal Cord Injury-Associated Neuropathology. — PubMed · 2019 · Journal Article
- Multipotent Neurotrophic Effects of Hepatocyte Growth Factor in Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Bibliometric and Visualized Analysis of Stem Cells Therapy for Spinal Cord Injury Based on Web of Science and CiteSpace in the Last 20 Years. — PubMed · 2019 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])