A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Edaravone attenuates ACSL4-dependent ferroptosis in spinal motor neurons following cardiac arrest in rats. — PubMed · 2026 · Journal Article
- Skeletal muscle lysate derived macroporous hydrogel repairs spinal cord injury via immunoregulation and axon regeneration. — PubMed · 2026 · Journal Article
- Thiolated Chitosan-Stearic Acid Thiol-Linked Biomimetic Hydrogels for Axonal Regrowth and Neuronal Tissue Regeneration. — PubMed · 2026 · Journal Article
- Elamipretide (SS-31) promotes recovery by preserving mitochondrial bioenergetics and neural remodeling after spinal cord injury. — PubMed · 2026 · Journal Article
- Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar-Limited Repair in Adult Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Rhynchophylline inhibits cluster of differentiation 36 (CD36) on endothelial cells to reduce fibrotic scar formation and enhance functional recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Silencing Adamts2 attenuates fibroblast-mediated fibrosis and promotes axonal regeneration in an in vitro model. — PubMed · 2026 · Journal Article
- Tetramethylpyrazine promotes spinal cord injury repair by modulating macrophage M1/M2 polarization via inhibition of the IL-6/JAK2/STAT3 pathway. — PubMed · 2026 · Journal Article
- Astrocyte-microglia crosstalk via CSF1 and IFN-β promotes central nervous system repair. — PubMed · 2026 · Journal Article
- Loss of function of Noggin inhibits glial scar formation and motor function recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Multifunctional Nanozyme Hydrogel for Oxidative Stress Scavenging and Mitophagy Activation in Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- Nanozyme-Switched Efferocytosis Initiation Platform Orchestrates Pathological Network Reprogramming to Promote Functional Recovery after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Impeding glial scarring hyperplasia and activating axon neogenesis via immunomodulatory microneedle patch for spinal cord repair. — PubMed · 2026 · Journal Article
- Indole-3-propionic acid inhibits astrocyte inflammation and promotes motor function recovery after spinal cord injury via the AhR/NF-κB/MAPK axis. — PubMed · 2026 · Journal Article
- A novel cannabidiol-derived small molecule ameliorates lower urinary tract dysfunction in mice with spinal cord injury via suppressing neuroinflammation. — PubMed · 2026 · Journal Article
- Imperatorin, a natural furanocoumarin alleviates chronic neuropathic pain by targeting GABAergic tone in an animal model of spinal cord injury. — PubMed · 2026 · Journal Article
- Netrin-1 Therapy Restores Partial Hindlimb Movement in a Rat Model of High-Severity Chronic Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Atractylodin Suppresses Fibrotic Scar Formation and Enhances Functional Recovery Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- [Effect of composite graphene-protein hydrogels on neural regeneration after spinal cord injury in rats]. — PubMed · 2026 · English Abstract
- Metformin-Loaded Schwann Cell Exosomes Reprogram Macrophages and Enhance Neurogenesis in Spinal Cord Injury Through PI3K/AKT Activation. — PubMed · 2026 · Journal Article
- Combination therapy of fingolimod-GelMA hydrogel loaded with neural stem cells and electrical stimulation promotes recovery of spinal cord injury. — PubMed · 2026 · Journal Article
- Identification of repopulated microglia-associated genes in microglia depleted/repopulated mice after spinal cord injury. — PubMed · 2026 · Journal Article
- Targeting Glutamate Excitotoxicity With Memantine Modulates Glial Response and Protects Motoneurons After Spinal Root Lesion. — PubMed · 2026 · Journal Article
- Three-Dimensional Printed Photo-Cross-Linked Gelatin Methacrylate Hydrogel Scaffold-Incorporated Mitochondria-Targeted Hydrogen Sulfide Donor-Loaded Liposomes for Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- Green Synthesis, Chemical Characterization, and Assessment of the Neuroprotective Properties of Zinc Nanoparticles on the Spinal Cord Injury Contusive Model in Rats. — PubMed · 2026 · Journal Article
- Persistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation. — PubMed · 2026 · Journal Article
- Effects of Electroacupuncture Stimulation on Motor Function Recovery in Mice After Spinal Cord Injury by Regulating Astrocyte Activation. — PubMed · 2026 · Journal Article
- Aldh1L1 Lineage Cells Contribute to the Functional Heterogeneity Within the Cells in Glial Scars After Spinal Cord Injury Through YAP Signaling. — PubMed · 2026 · Journal Article
- A microenvironment-responsive chitosan based injectable hydrogel with synergistic anti-inflammatory effects of triptolide and copper ions for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Modulation of inflammatory and regenerative responses by Galectin-3 after spinal cord injury in wild-type and Galectin-3 knockout mice. — PubMed · 2026 · Journal Article
- Multimodal electroconductive PLGA-based scaffold orchestrates neuroprotection and regeneration following severe spinal cord injury. — PubMed · 2026 · Journal Article
- Biomimetic core-shell GelMA microspheres co-delivering ANXA1, NGF, and fibronectin enable phase-matched immunomodulation and neurorepair after spinal cord injury. — PubMed · 2026 · Journal Article
- Disrupting CSPG-Driven Microglia-Astrocyte Crosstalk Enables Scar-Free Repair in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Molecular Changes in CSPG and Glial Scar Markers in Response to Subpial Chondroitinase ABC Treatment Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- NEDD4 promotes reactive astrogliosis by enhancing K63-linked ubiquitination and inhibiting chaperone-mediated autophagy degradation of YAP1. — PubMed · 2026 · Journal Article
- Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Regulatory T cells attenuate astrogliosis via IL-10/STAT3/PKC/vimentin signaling and promote neurological recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- AAD-2004 through clearing H(2)O(2) reduces astrocyte proliferation and promotes neural regeneration after spinal cord injury. — PubMed · 2025 · Journal Article
- Removal or inhibition of transglutaminase 2 decreases cellular stress, supporting tissue preservation, and recovery after SCI. — PubMed · 2025 · Journal Article
- Photobiomodulation Reduces Fibrous Scar Formation After Spinal Cord Injury by Downregulating CXCL3 Expression in Macrophages. — PubMed · 2025 · Journal Article
- Integrating sensitive motor tasks with histopathology detects sex differences in recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- Cellular Distribution of Pyruvate Kinase M2 After Spinal Cord Injury in Adult Rats. — PubMed · 2025 · Journal Article
- Spinal cord injury alters the therapeutic potential of olfactory ensheathing cells harvested in an autologous transplantation model. — PubMed · 2025 · Journal Article
- Cationic Liposome-Mediated Bcl-2 Gene Transfection in Bone Marrow Mesenchymal Stem Cells: A Novel Regenerative Approach for Spinal Cord Injury. — PubMed · 2025 · Journal Article
- The Combination of Sodium Tanshinone IIA Sulfonate and Mesenchymal Stem Cell-derived Exosomes Against Spinal Cord Injury via VEGF Pathway. — PubMed · 2025 · Journal Article
- Characterizing Non-Traumatic Spinal Cord Injury in Neonatal Sprague Dawley Rats. — PubMed · 2025 · Journal Article
- Morphological regulation of wound repair astrocytes by leucine zipper-bearing kinase-AKT signaling after spinal cord injury. — PubMed · 2025 · Journal Article
- Rolipram-Loaded PgP Nanotherapeutics via Intrathecal Administration Reduces Secondary Injury in a Rat Acute Moderate Contusion SCI Model. — PubMed · 2025 · Journal Article
- Targeting Fibrotic Scarring by Mechanoregulation of Il11ra1(+)/Itga11(+) Fibroblast Patterning Promotes Axon Growth after Spinal Cord Injury. — PubMed · 2025 · Journal Article
- 1,8-Cineole alleviates spinal cord injury by inhibiting microglial pyroptosis via the P38 MAPK and PI3K/AKT/NLRP3 signaling pathways to protects neurons. — PubMed · 2025 · Journal Article
- Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway. — PubMed · 2025 · Journal Article
- GLP-1R activation restores Gas6-driven efferocytosis in senescent foamy macrophages to promote neural repair. — PubMed · 2025 · Journal Article
- Investigating the Effects of Epac2 Activation in an In Vitro Cortical Mechanical Injury Model for Central Nervous System Repair. — PubMed · 2025 · Journal Article
- Nanoparticle and epothilone D combinatorial intervention improves motor performance and regeneration in chronic cervical spinal cord injury. — PubMed · 2025 · Journal Article
- Drebrin Upregulation Regulates Astrocyte Polarization and Supports Tissue Recovery After Spinal Cord Injury in Mice. — PubMed · 2025 · Journal Article
- Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization. — PubMed · 2025 · Journal Article
- Tibolone Improves Motor Recovery and Regulates Neuroinflammation and Gliosis in a Model of Traumatic Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Exploring the neuroprotective effects of bevacizumab in a preclinical animal model of spinal cord trauma. — PubMed · 2025 · Journal Article
- The effect of macromolecular crowders on deposition of extracellular matrix in astrocyte cultures. — PubMed · 2025 · Journal Article
- 3D-Bioprinted Scaffolds with Precise Factor Delivery for Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])