A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Anti-inflammatory treatment confirms rsfMRI and TSPO PET as biomarkers of functional connectivity and neuroinflammation in rat contusion spinal cord injuries. — PubMed · 2026 · Journal Article
- Matrix Metalloproteinase-Activatable Nanodrug Crossing Blood-Spinal Cord Barrier for On-Demand Drug Release in Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- Photobiomodulation Therapy with Zinc Oxide/Pheophorbide-a Nanoflakes Enhances Neurovascular Repair in Spinal Cord Injury Evidenced Using Photoacoustic Imaging. — PubMed · 2026 · Journal Article
- Obacunone Promotes Functional Recovery After Spinal Cord Injury by Attenuating Neuroinflammation by Targeting the TLR4/MyD88/p38 MAPK Pathway. — PubMed · 2026 · Journal Article
- Angiopep-2-engineered extracellular vesicles derived from spinal cord injury-responsive brown adipose tissue for targeted neuroinflammation modulation. — PubMed · 2026 · Journal Article
- NanoScript-Enabled Nonviral Transient Repression of Phosphatase and Tensin Homolog for Axonal Regeneration and Central Nervous System Injury Repair. — PubMed · 2026 · Journal Article
- Anti-inflammatory role of methylprednisolone in the hippocampus prevents depressive-like behavior after spinal cord injury in rats. — PubMed · 2026 · Journal Article
- Cerebrolysin-loaded platelet-rich plasma exosomes: Restoring immune homeostasis via TNF-α/IL-10 modulation and apoptosis targeting for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Intracellular small molecule/ion storm from Ca-phytate nanoparticle synergizes neural stem cell therapy and immunomodulation in spinal cord injury. — PubMed · 2026 · Journal Article
- Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1. — PubMed · 2026 · Journal Article
- Sirtuin1 modulates P53/Nrf2 pathway to promote spinal cord injury repair. — PubMed · 2026 · Journal Article
- Nanoparticle-Assembled Multifaceted Hydrogel Therapy Promotes Functional Recovery After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Glaucocalyxin A Promotes Spinal Cord Repair By Nrf2/HO-1 Pathway Activation to Suppress AIM2 Inflammasome Formation. — PubMed · 2026 · Journal Article
- LPS Pre-Conditioned Olfactory Ensheathing Cells Derived Extracellular Vesicle Regulate Microglia Polarization Through mir-1224/CD44/SLC7A11 Axis Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Multifunctional Diselenide-Based Antioxidative Nanozymes Promote Spinal Cord Repair via Oxidative Stress Alleviation and Immune Modulation. — PubMed · 2026 · Journal Article
- Opuntia ficus-indica (L.) Mill. Extract: From Chemical Characterization to Inflammatory Profiling and Its Potential Effects in a Zebrafish Model of Spinal Cord Injury-A Morphological and Molecular Study. — PubMed · 2026 · Journal Article
- A microenvironment-responsive chitosan based injectable hydrogel with synergistic anti-inflammatory effects of triptolide and copper ions for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Columbianadin improves M1 polarization of microglia after spinal cord injury by stabilizing PTEN and inhibiting the PI3K/AKT pathway. — PubMed · 2026 · Journal Article
- Ganoderma microsporum-derived fungal immunomodulatory protein (GMI) promotes functional recovery after spinal cord injury by modulating anti-inflammation and enhancing regeneration. — PubMed · 2026 · Journal Article
- Liposome-encapsulated clodronate and COX-2 inhibitor treatment impair ventilatory recovery but improve compensatory locomotor function following cervical spinal cord injury in rats. — PubMed · 2026 · Journal Article
- Local release of fibroblast growth factor 21 and cannabidiol promoting spinal cord nerve injury repair through activation of cannabinoid receptor 2. — PubMed · 2026 · Journal Article
- Morusin Alleviates Spinal Cord Injury in Rats by Regulating Macrophage Reprogramming Through Targeting RELA and NRF2. — PubMed · 2026 · Journal Article
- Naringenin alleviates spinal cord injury by ameliorating macrophage/microglia autophagy via progranulin stabilisation. — PubMed · 2026 · Journal Article
- Phillyrin Ameliorates Traumatic Spinal Cord Injury by Inhibiting Inflammation, Oxidative Stress, and Pyroptosis Through Modulation of the Nrf2/HO-1 Signaling Pathway. — PubMed · 2026 · Journal Article
- Tangeretin inhibits ferroptosis through the Nrf2/GPX4 pathway and promotes functional recovery in mice with spinal cord injury. — PubMed · 2026 · Journal Article
- The role of the iron-chelating agent deferoxamine in spinal cord injury: a systematic review and meta-analysis of preclinical studies. — PubMed · 2026 · Journal Article
- Clec7a-targeted Res@GelMA hydrogels regulate macrophage polarization to reduce neuroinflammation and promote spinal cord repair. — PubMed · 2026 · Journal Article
- Silencing of Ifi27l2a Attenuates Inflammation After Spinal Cord Injury by Regulating Microglial Polarization via JAK2/STAT3 Signaling. — PubMed · 2026 · Journal Article
- Exogenous IL-33 mitigates inflammatory responses by suppressing the NF-Κb signaling pathway, promoting blood-spinal cord barrier repair and neural functional recovery. — PubMed · 2026 · Journal Article
- Modulation of inflammatory and regenerative responses by Galectin-3 after spinal cord injury in wild-type and Galectin-3 knockout mice. — PubMed · 2026 · Journal Article
- Dual-engineered Treg-Exosome-IKVAV nanovesicles spatiotemporally sequentially regulate neuro-immune microenvironment to promote spinal cord injury repair. — PubMed · 2026 · Journal Article
- Multimodal electroconductive PLGA-based scaffold orchestrates neuroprotection and regeneration following severe spinal cord injury. — PubMed · 2026 · Journal Article
- Celastrol alleviates acute spinal cord injury by inhibiting microglial pyroptosis via the Neat1/NLRP3 pathway. — PubMed · 2026 · Journal Article
- A translational preclinical strategy for chronic spinal cord injury: neuroprotective and regenerative potential of botulinum neurotoxin type A combined with muscle atrophy prevention via electrostimulation. — PubMed · 2026 · Journal Article
- Biomimetic core-shell GelMA microspheres co-delivering ANXA1, NGF, and fibronectin enable phase-matched immunomodulation and neurorepair after spinal cord injury. — PubMed · 2026 · Journal Article
- Cinnamaldehyde mitigates spinal cord injury in rats through anti-inflammatory and anti-apoptotic pathways. — PubMed · 2026 · Journal Article
- Disrupting CSPG-Driven Microglia-Astrocyte Crosstalk Enables Scar-Free Repair in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism. — PubMed · 2026 · Journal Article
- Lysine-polydopamine nanoparticles for ameliorating acidic microenvironment and neuroprotection in spinal cord injury repair. — PubMed · 2026 · Journal Article
- Molecular Changes in CSPG and Glial Scar Markers in Response to Subpial Chondroitinase ABC Treatment Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Paeoniflorin Ameliorates Spinal Cord Injury by Controlling Apoptosis and Ferroptosis in H(2)O(2)-Damaged PC12 Cells. — PubMed · 2026 · Journal Article
- Schisantherin B exerts therapeutic effects on spinal cord injury via the PI3K/AKT signaling pathway. — PubMed · 2026 · Journal Article
- Silencing miR-134-5p promotes functional recovery after spinal cord injury by activating brain-derived neurotrophic factor (BDNF). — PubMed · 2026 · Journal Article
- USP22 overexpression mitigates spinal cord injury via NLRP3 pathway modulation. — PubMed · 2026 · Journal Article
- Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway. — PubMed · 2025 · Journal Article
- Galantamine-loaded PLGA nanoparticles reduce oxidative stress and inflammation in a rat model of spinal cord injury. — PubMed · 2025 · Journal Article
- Cabazitaxel Sustained-Release Nanoparticles Treat Spinal Cord Injury through Inhibiting Fibrin Deposition and Improving the Microenvironment. — PubMed · 2025 · Journal Article
- Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of IL-10 for Effective Management of Peripheral and Central Neuropathic Pain in Rats. — PubMed · 2025 · Journal Article
- Treg-microglia partnership in the injured spinal cord preserves Treg cell function and regulates microglial cholesterol metabolism. — PubMed · 2025 · Journal Article
- Farrerol confers neuroprotection in spinal cord injury by regulating macrophages/microglia polarization through the JAK2/STAT3 pathway. — PubMed · 2025 · Journal Article
- Monoammonium glycyrrhizinate ameliorates mitochondrial dysfunction-mediated oxidative stress and neuroinflammation via the NRF2/NQO1 axis after spinal cord injury. — PubMed · 2025 · Journal Article
- Synthesis of novel pyrazole derivatives and neuroprotective effect investigation. — PubMed · 2025 · Journal Article
- Mogroside V Ameliorates Spinal Cord Injury by Inhibiting M1 Microglia Polarization. — PubMed · 2025 · Journal Article
- Juglone promotes spinal cord injury recovery by suppressing pyroptosis and necroptosis through FOS/USP53/ubiquitination. — PubMed · 2025 · Journal Article
- Urolithin B promotes the functional recovery of spinal cord injury by alleviating neuroinflammation via the inhibition of NLRP3 signaling pathway. — PubMed · 2025 · Journal Article
- Function of orthologous fibroblast growth factor 11 protein in angiogenesis and immunomodulatory after spinal cord injury. — PubMed · 2025 · Journal Article
- Hyperoside alleviates macrophages and microglia-mediated neuroinflammation and oxidative stress through activating PI3K/AKT and Nrf2/HO-1 signaling pathway post spinal cord injury. — PubMed · 2025 · Journal Article
- Microglial SLC25A28 Knockout Mitigates Spinal Cord Injury in Mice by Inhibiting Heme Synthesis and Subsequent NOX2 Activation. — PubMed · 2025 · Journal Article
- Pantothenic acid-mediated inhibition of microglial inflammation via the JAK2/STAT3 pathway enhances motor function recovery after Spinal cord injury. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 13 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1741999 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 17 · this programme has 2063 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])