A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Neuroprotective effects of tetramethylpyrazine on spinal cord injury-Related neuroinflammation mediated by P2X7R/NLRP3 interaction. — PubMed · 2024 · Journal Article
- Effects of lercanidipine on traumatic spinal cord injury: an experimental study. — PubMed · 2024 · Journal Article
- Erythropoietin alleviates astrocyte pyroptosis by targeting the miR-325-3p/Gsdmd axis in rat spinal cord injury. — PubMed · 2024 · Journal Article
- CD44-targeting hyaluronic acid-selenium nanoparticles boost functional recovery following spinal cord injury. — PubMed · 2024 · Journal Article
- ACY1215 Exerts Anti-inflammatory Effects by Inhibition of NF-κB and STAT3 Signaling Pathway to Repair Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Gallic acid exerts protective effects in spinal cord injured rats through modulating microglial polarization. — PubMed · 2024 · Journal Article
- Synergistic Pharmacological Therapy to Modulate Glial Cells in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Oxygen therapy attenuates neuroinflammation after spinal cord injury. — PubMed · 2023 · Journal Article
- Artificially reprogrammed stem cells deliver transcytosable nanocomplexes for improved spinal cord repair. — PubMed · 2023 · Journal Article
- Catalytic antioxidant nanoparticles mitigate secondary injury progression and promote functional recovery in spinal cord injury model. — PubMed · 2023 · Journal Article
- Comparison of the Anti-Inflammatory Effects of Mouse Adipose- and Bone-Marrow-Derived Multilineage-Differentiating Stress-Enduring Cells in Acute-Phase Spinal Cord Injury. — PubMed · 2023 · Journal Article
- High rapamycin-loaded hollow mesoporous Prussian blue nanozyme targets lesion area of spinal cord injury to recover locomotor function. — PubMed · 2023 · Journal Article
- Resolvin D2 activates anti-inflammatory microglia via restoring autophagy flux and alleviate neuropathic pain following spinal cord injury in rats. — PubMed · 2023 · Journal Article
- Shinbaro2 enhances axonal extension beyond the glial scar for functional recovery in rats with contusive spinal cord injury. — PubMed · 2023 · Journal Article
- Resveratrol improves the prognosis of rats after spinal cord injury by inhibiting mitogen-activated protein kinases signaling pathway. — PubMed · 2023 · Journal Article
- Astaxanthin ameliorates spinal cord edema and astrocyte activation via suppression of HMGB1/TLR4/NF-κB signaling pathway in a rat model of spinal cord injury. — PubMed · 2023 · Journal Article
- Esculentoside A ameliorates BSCB destruction in SCI rat by attenuating the TLR4 pathway in vascular endothelial cells. — PubMed · 2023 · Journal Article
- Evaluation of photobiomodulation therapy (117 and 90s) on pain, regeneration, and epigenetic factors (HDAC 2, DNMT3a) expression following spinal cord injury in a rat model. — PubMed · 2023 · Journal Article
- Encapsulation of Selenium Nanoparticles and Metformin in Macrophage-Derived Cell Membranes for the Treatment of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Treg cells-derived exosomes promote blood-spinal cord barrier repair and motor function recovery after spinal cord injury by delivering miR-2861. — PubMed · 2023 · Journal Article
- An In Vitro and Ex Vivo Analysis of the Potential of GelMA Hydrogels as a Therapeutic Platform for Preclinical Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Phosphodiesterase 4 Inhibitor Roflupram Suppresses Inflammatory Responses Using Reducing Inflammasome in Microglia After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- pH/Temperature Responsive Curcumin-Loaded Micelle Nanoparticles Promote Functional Repair after Spinal Cord Injury in Rats via Modulation of Inflammation. — PubMed · 2023 · Journal Article
- Protective effect of TNIP2 on the inflammatory response of microglia after spinal cord injury in rats. — PubMed · 2023 · Journal Article
- Resveratrol inhibits ferroptosis via activating NRF2/GPX4 pathway in mice with spinal cord injury. — PubMed · 2023 · Journal Article
- Single-Cell Sequencing Reveals the Optimal Time Window for Anti-Inflammatory Treatment in Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Oral administration of procyanidin B2 3,3"-di-O-gallate ameliorates experimental autoimmune encephalomyelitis through immunosuppressive effects on CD4(+) T cells by regulating glycolysis. — PubMed · 2023 · Journal Article
- Curcumin-activated Olfactory Ensheathing Cells Improve Functional Recovery After Spinal Cord Injury by Modulating Microglia Polarization Through APOE/TREM2/NF-κB Signaling Pathway. — PubMed · 2023 · Journal Article
- Effects of albiflorin on oxidative stress and inflammatory responses in rats with acute spinal cord injury. — PubMed · 2023 · Journal Article
- The discovery of the new mechanism: Celastrol improves spinal cord injury by increasing cAMP through VIP-ADCYAP1R1-GNAS pathway. — PubMed · 2023 · Journal Article
- Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF-κB/NLRP3 signalling. — PubMed · 2023 · Journal Article
- Histone Deacetylase 3 Inhibition Ameliorates Microglia-Mediated Neuro-Inflammation Via the SIRT1/Nrf2 Pathway After Traumatic Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Curcumin-Containing polyphosphazene nanodrug for Anti-Inflammation and nerve regeneration to improve functional recovery after spinal cord injury. — PubMed · 2023 · Journal Article
- Long-term changes of Th17 and regulatory T cells in peripheral blood of dogs with spinal cord injury after intervertebral disc herniation. — PubMed · 2023 · Journal Article
- Carrier-Free Nanodrug Based on Co-Assembly of Methylprednisolone Dimer and Rutin for Combined Treatment of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Suppression of microglial Ccl2 reduces neuropathic pain associated with chronic spinal compression. — PubMed · 2023 · Journal Article
- ROS-Scavenging Hydrogels Synergize with Neural Stem Cells to Enhance Spinal Cord Injury Repair via Regulating Microenvironment and Facilitating Nerve Regeneration. — PubMed · 2023 · Journal Article
- Co-Administration of Resolvin D1 and Peripheral Nerve-Derived Stem Cell Spheroids as a Therapeutic Strategy in a Rat Model of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury. — PubMed · 2023 · Journal Article
- Ezetimibe attenuates functional impairment via inhibition of oxidative stress and inflammation in traumatic spinal cord injury. — PubMed · 2023 · Journal Article
- Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation. — PubMed · 2023 · Journal Article
- Lipocalin-2 Deficiency Diminishes Canonical NLRP3 Inflammasome Formation and IL-1β Production in the Subacute Phase of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- "Combo" Multi-Target Pharmacological Therapy and New Formulations to Reduce Inflammation and Improve Endogenous Remyelination in Traumatic Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Architecture-Engineered Electrospinning Cascade Regulates Spinal Microenvironment to Promote Nerve Regeneration. — PubMed · 2023 · Journal Article
- Hesperetin ameliorates spinal cord injury by inhibiting NLRP3 inflammasome activation and pyroptosis through enhancing Nrf2 signaling. — PubMed · 2023 · Journal Article
- Hydralazine plays an immunomodulation role of pro-regeneration in a mouse model of spinal cord injury. — PubMed · 2023 · Journal Article
- Short-chain fatty acids ameliorate spinal cord injury recovery by regulating the balance of regulatory T cells and effector IL-17(+) γδ T cells. — PubMed · 2023 · Journal Article
- The potential effects of polyunsaturated ω-3 fatty acids on spinal cord injury: A systematic review & meta-analysis of preclinical evidence. — PubMed · 2023 · Meta-Analysis
- Impact of intravenously administered cranial bone-derived mesenchymal stem cells on functional recovery in experimental spinal cord injury. — PubMed · 2023 · Journal Article
- Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation. — PubMed · 2023 · Journal Article
- Differential effects of NOX2 and NOX4 inhibition after rodent spinal cord injury. — PubMed · 2023 · Journal Article
- Disruption of the Blood-Spinal Cord Barrier using Low-Intensity Focused Ultrasound in a Rat Model. — PubMed · 2023 · Journal Article
- Composite Fibrin and Carbon Microfibre Implant to Modulate Postraumatic Inflammation after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Double-blinded placebo-controlled clinical trial of prophylactic omeprazole in dogs treated surgically for acute thoracolumbar intervertebral disc extrusion. — PubMed · 2023 · Randomized Controlled Trial, Veterinary
- Eumelanin decorated poly(lactic acid) electrospun substrates as a new strategy for spinal cord injury treatment. — PubMed · 2023 · Journal Article
- Quercetin in combination with hyperbaric oxygen therapy synergistically attenuates damage progression in traumatic spinal cord injury in a rat model. — PubMed · 2023 · Journal Article
- Mesenchymal stem cells in the treatment of spinal cord injury: Mechanisms, current advances and future challenges. — PubMed · 2023 · Journal Article
- Is TGR5 a therapeutic target for the treatment of spinal cord injury? — PubMed · 2023 · Journal Article
- Neuroprotective Effects of Milrinone on Acute Traumatic Brain Injury. — PubMed · 2023 · Journal Article
- S100A1 expression is increased in spinal cord injury and promotes inflammation, oxidative stress and apoptosis of PC12 cells induced by LPS via ERK signaling. — PubMed · 2023 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 13 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1741999 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 17 · this programme has 2063 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])