A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Tetramethylpyrazine and Astragaloside IV have synergistic effects against spinal cord injury-induced neuropathic pain via the OIP5-AS1/miR-34a/Sirt1/NF-κB axis. — PubMed · 2023 · Journal Article
- The aOECs Facilitate the Neuronal Differentiation of Neural Stem Cells in the Inflammatory Microenvironment Through Up-Regulation of Bioactive Factors and Activation of Wnt3/β-Catenin Pathway. — PubMed · 2023 · Journal Article
- Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury. — PubMed · 2023 · Journal Article
- Combination of single-cell and bulk RNA seq reveals the immune infiltration landscape and targeted therapeutic drugs in spinal cord injury. — PubMed · 2023 · Journal Article
- Multifunctional hydrogel modulates the immune microenvironment to improve allogeneic spinal cord tissue survival for complete spinal cord injury repair. — PubMed · 2023 · Journal Article
- Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury. — PubMed · 2023 · Journal Article
- Transplantation of olfactory ensheathing cells decreases local and serological monocyte chemoattractant protein 1 level during the acute phase of rat spinal cord injury. — PubMed · 2022 · Journal Article
- Treg cell-derived exosomes miR-709 attenuates microglia pyroptosis and promotes motor function recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Inflammatory Microenvironment-Responsive Nanomaterials Promote Spinal Cord Injury Repair by Targeting IRF5. — PubMed · 2022 · Journal Article
- Melittin regulates iron homeostasis and mediates macrophage polarization in rats with lumbar spinal stenosis. — PubMed · 2022 · Journal Article
- Codelivery of minocycline hydrochloride and dextran sulfate via bionic liposomes for the treatment of spinal cord injury. — PubMed · 2022 · Journal Article
- Neuroprotective effects of lovastatin against traumatic spinal cord injury in rats. — PubMed · 2022 · Journal Article
- Omega-3 fatty acids in the treatment of spinal cord injury: untapped potential for therapeutic intervention? — PubMed · 2022 · Journal Article
- Ulinastatin attenuates spinal cord injury by targeting AMPK/NLRP3 signaling pathway. — PubMed · 2022 · Journal Article
- Selective Calpain Inhibition Improves Functional and Histopathological Outcomes in a Canine Spinal Cord Injury Model. — PubMed · 2022 · Journal Article
- Astaxanthin ameliorates serum level and spinal expression of macrophage migration inhibitory factor following spinal cord injury. — PubMed · 2022 · Journal Article
- Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model. — PubMed · 2022 · Journal Article
- Forsythoside B attenuates neuro-inflammation and neuronal apoptosis by inhibition of NF-κB and p38-MAPK signaling pathways through activating Nrf2 post spinal cord injury. — PubMed · 2022 · Journal Article
- Cannabinoid receptor-2 attenuates neuroinflammation by promoting autophagy-mediated degradation of the NLRP3 inflammasome post spinal cord injury. — PubMed · 2022 · Journal Article
- Genetic deletion of the glucocorticoid receptor in Cx(3)cr1(+) myeloid cells is neuroprotective and improves motor recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Resveratrol suppresses microglial activation and promotes functional recovery of traumatic spinal cord via improving intestinal microbiota. — PubMed · 2022 · Journal Article
- Therapeutic Effects of Azithromycin on Spinal Cord Injury in Male Wistar Rats: A Role for Inflammatory Pathways. — PubMed · 2022 · Journal Article
- Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA(2)), UCM-14216, Ameliorates Spinal Cord Injury in Mice. — PubMed · 2022 · Journal Article
- Inhibition of IL1R1 or CASP4 attenuates spinal cord injury through ameliorating NLRP3 inflammasome-induced pyroptosis. — PubMed · 2022 · Journal Article
- Macrophages Treated with VEGF and PDGF Exert Paracrine Effects on Olfactory Ensheathing Cell Function. — PubMed · 2022 · Journal Article
- Exosome-Shuttled miR-672-5p from Anti-Inflammatory Microglia Repair Traumatic Spinal Cord Injury by Inhibiting AIM2/ASC/Caspase-1 Signaling Pathway Mediated Neuronal Pyroptosis. — PubMed · 2022 · Journal Article
- Graphene-collagen cryogel controls neuroinflammation and fosters accelerated axonal regeneration in spinal cord injury. — PubMed · 2022 · Journal Article
- α-Cyperone Improves Rat Spinal Cord Tissue Damage via Akt/Nrf2 and NF-κB Pathways. — PubMed · 2022 · Journal Article
- WKYMVm/FPR2 Alleviates Spinal Cord Injury by Attenuating the Inflammatory Response of Microglia. — PubMed · 2022 · Journal Article
- Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization. — PubMed · 2022 · Journal Article
- Progranulin Promotes Functional Recovery in Rats with Acute Spinal Cord Injury via Autophagy-Induced Anti-inflammatory Microglial Polarization. — PubMed · 2022 · Journal Article
- LncRNA KCNQ1OT1 promotes the apoptosis and inflammatory response of microglia by regulating the miR-589-5p/NPTN axis after spinal cord injury. — PubMed · 2022 · Journal Article
- BET protein inhibition promotes non-myeloid cell mediated neuroprotection after rodent spinal cord contusion. — PubMed · 2022 · Journal Article
- PBMSCs transplantation facilitates functional recovery after spinal cord injury by regulating microglia/macrophages plasticity. — PubMed · 2022 · Journal Article
- Effect of morroniside on the transcriptome profiles of rat in injured spinal cords. — PubMed · 2022 · Journal Article
- Conducting molybdenum sulfide/graphene oxide/polyvinyl alcohol nanocomposite hydrogel for repairing spinal cord injury. — PubMed · 2022 · Journal Article
- Highly bioactive iridium metal-complex alleviates spinal cord injury via ROS scavenging and inflammation reduction. — PubMed · 2022 · Journal Article
- Ac-SDKP peptide improves functional recovery following spinal cord injury in a preclinical model. — PubMed · 2022 · Journal Article
- CAQK modification enhances the targeted accumulation of metformin-loaded nanoparticles in rats with spinal cord injury. — PubMed · 2022 · Journal Article
- Heat-Shock Proteins Can Potentiate the Therapeutic Ability of Cryopreserved Mesenchymal Stem Cells for the Treatment of Acute Spinal Cord Injury in Dogs. — PubMed · 2022 · Journal Article
- Long non-coding RNA-small nucleolar RNA host gene 7 regulates inflammatory responses following spinal cord injury by regulating the microRNA-449a/TNF-α-induced protein 3-interacting protein 2 axis. — PubMed · 2022 · Journal Article
- Macrophage polarization in vitro and in vivo modified by contact with fragmented chitosan hydrogel. — PubMed · 2022 · Journal Article
- Sustained developmental endothelial locus-1 overexpression promotes spinal cord injury recovery in mice through the SIRT1/SERCA2 signaling pathway. — PubMed · 2022 · Journal Article
- The Effects of the Combination of Mesenchymal Stromal Cells and Nanofiber-Hydrogel Composite on Repair of the Contused Spinal Cord. — PubMed · 2022 · Journal Article
- Effect of Sirtuin-1 and Wnt/β-Catenin Signaling Pathway in Rat Model of Spinal Cord Injury. — PubMed · 2022 · Journal Article The source marks this record as retracted.
- Photobiomodulation Attenuates Neurotoxic Polarization of Macrophages by Inhibiting the Notch1-HIF-1α/NF-κB Signalling Pathway in Mice With Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Ultrasound stimulation improves inflammatory resolution, neuroprotection, and functional recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Melatonin ameliorates bupivacaine-induced spinal neurotoxicity in rats by suppressing neuronal NLRP3 inflammasome activation. — PubMed · 2022 · Journal Article
- Glycyrrhizic Acid Attenuates the Inflammatory Response After Spinal Cord Injury by Inhibiting High Mobility Group Box-1 Protein Through the p38/Jun N-Terminal Kinase Signaling Pathway. — PubMed · 2022 · Journal Article
- Ginsenoside Rg1 inhibits oxidative stress and inflammation in rats with spinal cord injury via Nrf2/HO-1 signaling pathway. — PubMed · 2022 · Journal Article
- Inhalation of dimethyl fumarate-encapsulated solid lipid nanoparticles attenuate clinical signs of experimental autoimmune encephalomyelitis and pulmonary inflammatory dysfunction in mice. — PubMed · 2022 · Journal Article
- In vitro modulation of Schwann cell behavior by VEGF and PDGF in an inflammatory environment. — PubMed · 2022 · Journal Article
- Minocycline-Loaded Poly(α-Lipoic Acid)-Methylprednisolone Prodrug Nanoparticles for the Combined Anti-Inflammatory Treatment of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Inhibition of the NLRP3 inflammasome by OLT1177 induces functional protection and myelin preservation after spinal cord injury. — PubMed · 2022 · Journal Article
- Phoenixin-14 Promotes the Recovery of Neurological Dysfunction After Spinal Cord Injury by Regulating Microglial Polarization via PTEN/Akt Signaling Pathway. — PubMed · 2022 · Journal Article
- The Long-Term Efficacy Study of Multiple Allogeneic Canine Adipose Tissue-Derived Mesenchymal Stem Cells Transplantations Combined With Surgery in Four Dogs With Lumbosacral Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Anti-inflammatory and antioxidant effects of astaxanthin following spinal cord injury in a rat animal model. — PubMed · 2021 · Journal Article
- Cell-adaptable dynamic hydrogel reinforced with stem cells improves the functional repair of spinal cord injury by alleviating neuroinflammation. — PubMed · 2021 · Journal Article
- Exerting the Appropriate Application of Methylprednisolone in Acute Spinal Cord Injury Based on Time Course Transcriptomics Analysis. — PubMed · 2021 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 13 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1741999 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 17 · this programme has 2063 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])